Down-regulation of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1), an endogenous allosteric α7 nicotinic acetylcholine receptor modulator, in murine and human asthmatic conditions

Biochemical and Biophysical Research Communications

Volumn 398, Issue 4, 2010, Pages 713-718

  Narumoto, Osamu ^a,b   Horiguchi, Kazuhide ^c   Horiguchi, Satomi ^c   Moriwaki, Yasuhiro ^d   Takano Ohmuro, Hiromi ^a   Shoji, Shunsuke ^e   Misawa, Hidemi ^d   Yamashita, Naohide ^f   Nagase, Takahide ^b   Kawashima, Koichiro ^a   Yamashita, Naomi ^a  

^a MUSASHINO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF FUKUI   (Japan)

^d KEIO UNIVERSITY   (Japan)

^e TOKYO NATIONAL HOSPITAL   (Japan)

^f UNIVERSITY OF TOKYO   (Japan)

Author keywords

Acetylcholine; Asthma; Bronchial epithelial cells; Mucus secreting cells; Nicotinic receptors

Indexed keywords

ALUMINUM HYDROXIDE; BUNGAROTOXIN RECEPTOR; INTERLEUKIN 13; OVALBUMIN; SLURP 1 PROTEIN; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMATIC STATE; BRONCHIOLE; BRONCHUS MUCOSA; CELL CULTURE; CELL LOSS; CILIATED EPITHELIUM; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG PARENCHYMA; METAPLASIA; MOUSE; MUCOUS CELL; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION;

ANIMALS; ANTIGENS, LY; ASTHMA; BIOLOGICAL MARKERS; BRONCHI; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; RECEPTORS, NICOTINIC; RESPIRATORY MUCOSA; RNA, MESSENGER; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

ANIMALIA; MURINAE; MUS;

EID: 77955418129     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.07.006     Document Type: Article

References (34)

1. Meurs H., Gosens R., Zaagsma J. Airway hyperresponsiveness in asthma: lessons from in vitro model systems and animal models. Eur. Respir. J. 2008, 32:487-502.
2. Gwilt C.R., Donnelly L.E., Rogers D.F. The non-neuronal cholinergic system in the airways: an unappreciated regulatory role in pulmonary inflammation?. Pharmacol. Ther. 2007, 115:208-222.
3. Barnes P.J. Distribution of receptor targets in the lung. Proc. Am. Thorac. Soc. 2004, 1:345-351.
4. Kummer W., Lips K.S., Pfeil U. The epithelial cholinergic system of the airways. Histochem. Cell Biol. 2008, 130:219-234.
5. Kawashima K., Fujii T. Extraneuronal cholinergic system in lymphocytes. Pharmacol. Ther. 2000, 86:29-48.
6. Kawashima K., Fujii T. Expression of non-neuronal acetylcholine in lymphocytes and its contribution to the regulation of immune function. Front. Biosci. 2004, 9:2063-2085.
7. Fujii T., Takada-Takatori Y., Kawashima K. Basic and clinical aspects of non-neuronal acetylcholine: expression of an independent, non-neuronal cholinergic system in lymphocytes and its clinical significance in immunotherapy. J. Pharmacol. Sci. 2008, 106:186-192.
8. Grando S.A., Kawashima K., Kirkpatrick C.J., Wessler I. Recent progress in understanding the non-neuronal cholinergic system in humans. Life Sci. 2007, 80:2181-2185.
9. Grando S.A., Kawashima K., Wessler I. Introduction: the non-neuronal cholinergic system in humans. Life Sci. 2003, 72:2009-2012.
10. Grando S.A. Basic and clinical aspects of non-neuronal acetylcholine: biological and clinical significance of non-canonical ligands of epithelial nicotinic acetylcholine receptors. J. Pharmacol. Sci. 2008, 106:174-179.
11. Borovikova L.V., Ivanova S., Zhang M., Yang H., Botchkina G.I., Watkins L.R., Wang H., Abumrad N., Eaton J.W., Tracey K.J. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 2000, 405:458-462.
12. Saeed R.W., Varma S., Peng-Nemeroff T., Sherry B., Balakhaneh D., Huston J., Tracey K.J., Al-Abed Y., Metz C.N. Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation. J. Exp. Med. 2005, 201:1113-1123.
13. Wang H., Yu M., Ochani M., Amella C.A., Tanovic M., Susarla S., Li J.H., Yang H., Ulloa L., Al-Abed Y., Czura C.J., Tracey K.J. Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation. Nature 2003, 421:384-388.
14. Maouche K., Polette M., Jolly T., Medjber K., Cloez-Tayarani I., Changeux J.P., Burlet H., Terryn C., Coraux C., Zahm J.M., Birembaut P., Tournier J.M. {α}7 Nicotinic acetylcholine receptor regulates airway epithelium differentiation by controlling basal cell proliferation. Am. J. Pathol. 2009, 175:1868-1882.
15. Adermann K., Wattler F., Wattler S., Heine G., Meyer M., Forssmann W.G., Nehls M. Structural and phylogenetic characterization of human SLURP-1, the first secreted mammalian member of the Ly-6/uPAR protein superfamily. Protein Sci. 1999, 8:810-819.
16. Chimienti F., Hogg R.C., Plantard L., Lehmann C., Brakch N., Fischer J., Huber M., Bertrand D., Hohl D. Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda. Hum. Mol. Genet. 2003, 12:3017-3024.
17. Horiguchi K., Horiguchi S., Yamashita N., Irie K., Masuda J., Takano-Ohmuro H., Himi T., Miyazawa M., Moriwaki Y., Okuda T., Misawa H., Ozaki H., Kawashima K. Expression of SLURP-1, an endogenous alpha7 nicotinic acetylcholine receptor allosteric ligand, in murine bronchial epithelial cells. J. Neurosci. Res. 2009, 87:2740-2747.
18. Doherty T., Broide D. Cytokines and growth factors in airway remodeling in asthma. Curr. Opin. Immunol. 2007, 19:676-680.
19. Mitchell J., Dimov V., Townley R.G. IL-13 and the IL-13 receptor as therapeutic targets for asthma and allergic disease. Curr. Opin. Investig. Drugs 2010, 11:527-534.
20. Moriwaki Y., Watanabe Y., Shinagawa T., Kai M., Miyazawa M., Okuda T., Kawashima K., Yabashi A., Waguri S., Misawa H. Primary sensory neuronal expression of SLURP-1, an endogenous nicotinic acetylcholine receptor ligand. Neurosci. Res. 2009, 64:403-412.
21. Mastrangeli R., Donini S., Kelton C.A., He C., Bressan A., Milazzo F., Ciolli V., Borrelli F., Martelli F., Biffoni M., Serlupi-Crescenzi O., Serani S., Micangeli E., El Tayar N., Vaccaro R., Renda T., Lisciani R., Rossi M., Papoian R. A.R.S. Component B: structural characterization, tissue expression and regulation of the gene and protein (SLURP-1) associated with Mal de Meleda. Eur. J. Dermatol. 2003, 13:560-570.
22. Matsuo Y., Ishihara T., Ishizaki J., Miyamoto K., Higaki M., Yamashita N. Effect of betamethasone phosphate loaded polymeric nanoparticles on a murine asthma model. Cell Immunol. 2009, 260:33-38.
23. Yamashita N., Tashimo H., Matsuo Y., Ishida H., Yoshiura K., Sato K., Kakiuchi T., Ohta K. Role of CCL21 and CCL19 in allergic inflammation in the ovalbumin-specific murine asthmatic model. J. Allergy Clin. Immunol. 2006, 117:1040-1046.
24. Kondo M., Tamaoki J., Takeyama K., Nakata J., Nagai A. Interleukin-13 induces goblet cell differentiation in primary cell culture from Guinea pig tracheal epithelium. Am. J. Respir. Cell Mol. Biol. 2002, 27:536-541.
25. Ross A.J., Dailey L.A., Brighton L.E., Devlin R.B. Transcriptional profiling of mucociliary differentiation in human airway epithelial cells. Am. J. Respir. Cell Mol. Biol. 2007, 37:169-185.
26. You Y., Richer E.J., Huang T., Brody S.L. Growth and differentiation of mouse tracheal epithelial cells: selection of a proliferative population. Am. J. Physiol. Lung Cell. Mol. Physiol. 2002, 283:L1315-L1321.
27. Laoukili J., Perret E., Willems T., Minty A., Parthoens E., Houcine O., Coste A., Jorissen M., Marano F., Caput D., Tournier F. IL-13 alters mucociliary differentiation and ciliary beating of human respiratory epithelial cells. J. Clin. Invest. 2001, 108:1817-1824.
28. Medoff B.D., Thomas S.Y., Luster A.D. T cell trafficking in allergic asthma: the ins and outs. Annu. Rev. Immunol. 2008, 26:205-232.
29. Arredondo J., Chernyavsky A.I., Webber R.J., Grando S.A. Biological effects of SLURP-1 on human keratinocytes. J. Invest. Dermatol. 2005, 125:1236-1241.
30. Kikuchi H., Itoh J., Fukuda S. Chronic nicotine stimulation modulates the immune response of mucosal T cells to Th1-dominant pattern via nAChR by upregulation of Th1-specific transcriptional factor. Neurosci. Lett. 2008, 432:217-221.
31. Mishra N.C., Rir-Sima-Ah J., Langley R.J., Singh S.P., Pena-Philippides J.C., Koga T., Razani-Boroujerdi S., Hutt J., Campen M., Kim K.C., Tesfaigzi Y., Sopori M.L. Nicotine primarily suppresses lung Th2 but not goblet cell and muscle cell responses to allergens. J. Immunol. 2008, 180:7655-7663.
32. Vassallo R., Tamada K., Lau J.S., Kroening P.R., Chen L. Cigarette smoke extract suppresses human dendritic cell function leading to preferential induction of Th-2 priming. J. Immunol. 2005, 175:2684-2691.
33. Fujii Y.X., Fujigaya H., Moriwaki Y., Misawa H., Kasahara T., Grando S.A., Kawashima K. Enhanced serum antigen-specific IgG1 and proinflammatory cytokine production in nicotinic acetylcholine receptor alpha7 subunit gene knockout mice. J. Neuroimmunol. 2007, 189:69-74.
34. Favre B., Plantard L., Aeschbach L., Brakch N., Christen-Zaech S., de Viragh P.A., Sergeant A., Huber M., Hohl D. SLURP1 is a late marker of epidermal differentiation and is absent in Mal de Meleda. J Invest Dermatol 2007, 127:301-308.