Intraepidermal nerve fiber density reduction as a marker of preclinical asymptomatic small-fiber sensory neuropathy in hypothyroid patients

European Journal of Endocrinology

Volumn 163, Issue 2, 2010, Pages 279-284

  Magri, Flavia ^a   Buonocore, Michelangelo ^b   Oliviero, Antonio ^c   Rotondi, Mario ^a   Gatti, Anna ^b   Accornero, Silvia ^a   Camera, Antonella ^a   Chiovato, Luca ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b IRCCS   (Italy)

^c HOSPITAL NACIONAL DE PARAPLÉJICOS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

THYROGLOBULIN ANTIBODY; THYROID PEROXIDASE ANTIBODY; THYROTROPIN; THYROXINE;

ADULT; AGED; ARTICLE; BASEMENT MEMBRANE; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTRONEUROGRAPHY; FEMALE; HUMAN; HUMAN TISSUE; HYPOTHYROIDISM; IMMUNOFLUORESCENCE; LEG; MALE; NERVE FIBER; PERONEUS NERVE; PRIORITY JOURNAL; SCIATIC NERVE; SENSORY NERVE; SENSORY NERVE CONDUCTION; SENSORY NEUROPATHY; SKIN BIOPSY; SKIN NERVE; THIGH;

ADULT; AGED; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; HYPOTHYROIDISM; MALE; MIDDLE AGED; NERVE FIBERS; NEURAL CONDUCTION; PERIPHERAL NERVOUS SYSTEM DISEASES; SEVERITY OF ILLNESS INDEX; SKIN; STATISTICS, NONPARAMETRIC; THYROTROPIN; THYROXINE;

EID: 77955404735     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-10-0285     Document Type: Article

References (27)

1. Nemni R, Bottacchi E, Fazio R, Mamoli A, Corbo M, Camerlingo M, Galardi G, Erenbourg L & Canal N. Polyneuropathy in hypothyroidism: clinical, electrophysiological and morphological findings in four cases. Journal of Neurology, Neurosurgery, and Psychiatry 1987 50 1454-1460.
2. Beghi E, Delodovici ML, Bogliun G, Crespi V, Paleari F, Gamba P, Capra M & Zarrelli M. Hypothyroidism and polyneuropathy. Journal of Neurology, Neurosurgery, and Psychiatry 1989 52 1420-1423.
3. Lin KP, Kwan SY, Chen SY, Chen SS, Yeung KB, Chia LG & Wu ZA. Generalized neuropathy in Taiwan: an etiologic survey. Neuroepidemiology 1993 12 257-261.
4. Rudolph T & Farbu E. Hospital-referred polyneuropathies - causes, prevalences, clinical- and neurophysiological findings. European Journal of Neurology 2007 14 603-608.
5. 4 replacement therapy. Clinical Endocrinology 1999 51 237-242.
6. Crevasse LE & Logue RB. Peripheral neuropathy in myxedema. Annals of Internal Medicine 1959 50 1433-1437.
7. Somay G, Oflazoǧlu B, Us O & Surardamar A. Neuromuscular status of thyroid diseases: a prospective clinical and electrodiagnostic study. Electromyography and Clinical Neurophysiology 2007 47 67-78. (Pubitemid 46566878)
8. Penza P, Lombardi R, Camozzi F, Ciano C & Lauria G. Painful neuropathy in subclinical hypothyroidism: clinical and neuropathological recovery after hormone replacement therapy. Neurological Sciences 2009 30 149-151.
9. Devigili G, Tugnoli V, Penza P, Camozzi F, Lombardi R, Melli G, Broglio L, Granieri E & Lauria G. The diagnostic criteria for small fiber neuropathy: from symptoms to neuropathology. Brain 2008 131 1912-1925.
10. England JD, Gronseth GS, Franklin G, Carter GT, Kinsella LJ, Cohen JA, Asbury AK, Szigeti K, Lupski JR, Latov N, Lewis RA, Low PA, Fisher MA, Herrmann DN, Howard JF Jr, Lauria G, Miller RG, Polydefkis M, Sumner AJ & American Academy of Neurology. Practice parameter: evaluation of distal symmetric polyneuropathy: role of autonomic testing, nerve biopsy, and skin biopsy (an evidence-based review). Report of the American Academy of Neurology, American Association of Neuromuscular and Electrodiagnostic Medicine, and American Academy of Physical Medicine and Rehabilitation. Neurology 2009 72 177-184.
11. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2009 32 S62-S67.
12. Lauria G, Cornblath DR, Johansson O, McArthur JC, Mellgren SI, Nolano M, Rosenberg N, Sommer C & European Federation of Neurological Societies. EFNS guidelines on the use of skin biopsy in the diagnosis of peripheral neuropathy. European Journal of Neurology 2005 12 747-758.
13. Hollowell JG, Staehling NW, Flanders WD, Hannon WH, Gunter EW, Spencer CA & Braverman LE. Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). Journal of Clinical Endocrinology and Metabolism 2002 87 489-499.
14. Canaris GJ, Manowitz NR, Mayor G & Ridgway EC. The Colorado thyroid disease prevalence study. Archives of Internal Medicine 2000 160 526-534. (Pubitemid 30112276)
15. Duyff RF, Van den Bosch J, Laman DM, van Loon BJ & Linssen WH. Neuromuscular findings in thyroid dysfunction: a prospective clinical and electrodiagnostic study. Journal of Neurology, Neurosurgery, and Psychiatry 2000 68 750-755.
16. El-Salem K & Ammari F. Neurophysiological changes in neurologically asymptomatic hypothyroid patients: a prospective cohort study. Journal of Clinical Neurophysiology 2006 23 568-572.
17. Ørstavik K, Norheim I & Jørum E. Pain and small-fiber neuropathy in patients with hypothyroidism. Neurology 2006 67 786-791.
18. Hlubocky A, Wellik K, Ross MA, Smith BE, Hoffman-Snyder C, Demaerschalk BM & Wingerchuk DM. Skin biopsy for diagnosis of small fiber neuropathy: a critically appraised topic. Neurologist 2010 16 61-63.
19. Nebuchennykh M, Løseth S & Mellgren SI. Aspects of peripheral nerve involvement in patients with treated hypothyroidism. European Journal of Neurology 2010 17 67-72.
20. Magri F, Oliviero A, Rotondi M & Chiovato L. Comments on 'aspects of peripheral nerve involvement in patients with treated hypothyroidism'. European Journal of Neurology 2010 17 e13.
21. Khedr EM, El Toony LF, Tarkhan MN & Abdella G. Peripheral and central nervous system alterations in hypothyroidism: electrophysiological findings. Neuropsychobiology 2000 41 88-94. (Pubitemid 30058129)
22. Sommer C & Lauria G. Skin biopsy in the management of peripheral neuropathy. Lancet Neurology 2007 6 632-642. (Pubitemid 46921057)
23. Nodera H, Barbano RL, Henderson D & Herrmann DN. Epidermal reinnervation concomitant with symptomatic improvement in a sensory neuropathy. Muscle & Nerve 2003 27 507-509.
24. Gøransson LG, Herigstad A, Tjensvoll AB, Harboe E, Mellgren SI & Omdal R. Peripheral neuropathy in primary Sjogren syndrome: a population-based study. Archives of Neurology 2006 63 1612-1615.
25. Ringel MD & Mazzaferri EL. Subclinical thyroid dysfunction - can there be a consensus about the consensus? Journal of Clinical Endocrinology and Metabolism 2005 90 588-590.
26. Cooper DS. Subclinical thyroid disease: consensus or conundrum? Clinical Endocrinology 2004 60 410-412.
27. Biondi B & Cooper DS. The clinical significance of subclinical thyroid dysfunction. Endocrine Reviews 2008 29 76-131. (Pubitemid 351252748)