Neuromuscular symptoms and dysfunction in subclinical hypothyroid patients: Beneficial effect of L-T4 replacement therapy

Clinical Endocrinology

Volumn 51, Issue 2, 1999, Pages 237-242

  Monzani, Fabio ^a   Caraccio, Nadia ^a   Del Guerra, Paolo ^a   Casolaro, Arturo ^a   Ferrannini, Eleuterio ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; PARATHYROID HORMONE;

ADULT; ARTICLE; CALCIUM BALANCE; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROMYOGRAM; FOLLOW UP; HUMAN; HYPOTHYROIDISM; NEUROMUSCULAR DISEASE; PRIORITY JOURNAL; QUESTIONNAIRE;

ADOLESCENT; ADULT; AGED; CALCIUM; CASE-CONTROL STUDIES; ELECTROMYOGRAPHY; FEMALE; HORMONE REPLACEMENT THERAPY; HUMANS; HYPOTHYROIDISM; MALE; MIDDLE AGED; NEUROMUSCULAR DISEASES; THYROTROPIN; THYROXINE;

EID: 0032775440     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.1999.00790.x     Document Type: Article

References (28)

1. Althaus, B.U., Staub, J.J., Ryff-De Leche, A., Oberhansli, A. & Stahelin, H.B. (1988) LDL/HDL changes in subclinical hypothyroidism: possible risk factors for coronary heart disease. Clinical Endocrinology, 28, 157-163.
2. Auwerx, J. & Bouillon, R. (1986) Mineral and bone metabolism in thyroid disease: a review. Quartery Journal Medicine, 232, 737-752.
3. Bastron, J.A. (1984) Neuropathy in diseases of the thyroid and pituitary glands. In: Peripheral neuropathy. (Eds. P.J. Dyck, P.K. Thomas, E.H. Lambert & R.P. Bunge). pp. 1833-1846. Saunders, Philadelphia.
4. Beghi, E., Defodovici, M.L., Bogfiun, G., Crespi, V., Paleari, F., Gamba, P., Capra, M. & Zarrelli, M. (1989) Hypothyroidism and polyneuropathy. Journal of Neurology, Neurosurgery and Psychiatry, 52, 1420-1423.
5. Bouillon, R. & De Moor, P. (1974) Parathyroid function in patients with hyper-and hypothyroidism. Journal of Clinical Endocrinology and Metabolism, 38, 999-1002.
6. Brodtkorb, E., Gimse, R., Antonaci, F., Ellertsen, B., Sand, T., Sulg, I., & Sjaastad, O. (1990) Hyperventilation syndrome: clinical, ventilatory, and personality characteristics as observed in neurological practice. Acta Neurologica Scandinavica, 81, 307-313.
7. Burnett, J.R., Crooke, M.J., Delahunt, J.W. & Feek, C.M. (1994) Serum enzymes in hypothyroidism. New Zeland Medical Journal, 107, 355-358.
8. 4 therapy. Clinical Endocrinology, 33, 519-523.
9. Chu, D.T.W., Shikama, H., Khatra, B.S. & Exton, J.H. (1985) Effect of altered thyroid status on Beta-adrenergic action of skeletal muscle metabolism. Journal of Biological Chemistry, 250, 994-1000.
10. Cooper, D.S., Halpern, R., Wood, L.C., Levin, A.A. & Ridgway, B.C. (1984) L-thyroxine therapy in subclinical hypothyroidism: a double-blind, placebo-controlled trial. Annals of Internal Medicine, 101, 18-24.
11. Fritzel, D., Malleson, A. & Marks, V. (1967) Plasma levels of ionized calcium and magnesium in thyroid disease. Lancet, 1, 1360-1361.
12. 2+ channels and β-receptors during short-and long-term hyper-and hypothyroidism. European Journal of Endocrinology, 130, 171-179.
13. Helfand, M. & Crapo, L.M. (1990) Screening for thyroid disease. Annals of Internal Medicine, 112, 840-849.
14. Khaleeli, A.A., Gohil, K., McPhail, G., Round, J.M. & Edwards, R.H.T. (1983) Muscle morphology and metabolism in hypothyroid myopathy: effects of treatment. Journal of Clinical Pathology, 36, 519-526.
15. Khaleeli, A.A. & Edwards, R.H. (1984) Effect of treatment on skeletal muscle dysfunction in hypothyroidism. Clinical Science, 66, 63-67.
16. Klein, I., Parker, M., Shebert, R., Ayyar, D.R. & Levey, G.S. (1981) Hypothyroidism presenting as muscle stiffness and pseudohypertrophy: Hoffmann's syndrome. The American Journal of Medicine, 70, 891-894.
17. Kukumberg, P. (1991) Side-specific electromyographic differences in tetany. Lancet, 337, 1607.
18. Leijendekker, W.J., van Hardeveld, C. & Kassenaar, A.H. (1985) Coupled diminished energy turnover and phosphorilase a formation in contracting hypothyroid rat muscle. Metabolism, 34, 437-441.
19. Miller, R.G., Boska, M.D., Moussavi, R..S., Carson, P.J. & Weiner, M.W. (1988) P-nuclear magnetic resonance studies of high energy phosphates and pH in human muscle fatigue. Comparison of aerobic and anaerobic exercise. Journal of Clinical Investigation, 81, 1190-1196.
20. Monzani, F., Pruneti, C.A., De Negri, F., Simoncini, M., Neri, S., Di Bello, V., Baracchini Muratorio, G. & Baschicri, L. (1991) Preclinical hypothyroidism: early involvement of memory function, behavioural responsiveness and myocardial contractility. Minerva Endocrinologica, 16, 113-118.
21. Monzani, F., Del Guerra, P., Caraccio, N., Pruneti, C.A., Pucci, E., Luisi, M. & Baschieri, L. (1993) Subclinical hypothyroidism: neurobehavioral features and beneficial effect of L-thyroxine treatment. The Clinical Investigator, 71, 367-371.
22. Monzani, F., Caraccio, N., Siciliano, G., Manca, L., Murri, L. & Ferrannini, E. (1997) Clinical and biochemical features of muscle dysfunction in subclinical hypothyroidism. Journal of Clinical Endocrinology and Metabolism, 82, 3315-3318.
23. Nystrom, E., Caidahl, K. & Fager, G. (1988) A double-blind cross-over 12-month study of L-thyroxine treatment of women with 'sub clinical' hypothyroidism. Clinical Endocrinology, 29, 63-75.
24. Paci, A., Sartucci, F., Rossi, B., Migliaccio, P. & Pallesi, R. (1984) The clinical signs of spasmophilia in children. Medical and Surgical Pediatry, 6, 823-829.
25. Ross, D. (1995) Subclinical hypothyroidism. In: Werner and Ingbar's The Thyroid (Eds. R.D. Utiger & L.E. Braverman), pp. 1010-1015. Lippincot-Raven, New York.
26. Rossi, B., Sartucci, F. & Starita, A. (1984) Automatic analysis of the spontaneous EMG activity during ischaemic test in tetany. Electromyography and Clinical Neurophysiology, 24, 75-80.
27. Tonner, D.R. & Schlechte, J.A. (1993) Neurologic complications of thyroid and parathyroid disease. Medical Clinics of North America, 77, 251-262.
28. Waldstein, S.S., Bronsky, D., Shrifter, H.B. & Oester, Y.T. (1958) The electromyogram in myxedema. Archives of Internal Medicine, 101, 97-102.