Identification of pathway-biased and deleterious melatonin receptor mutants in autism spectrum disorders and in the general population

PLoS ONE

Volumn 5, Issue 7, 2010, Pages

  Chaste, Pauline ^a,b   Clement, Nathalie ^c   Mercati, Oriane ^a,b   Guillaume, Jean Luc ^c   Delorme, Richard ^a,b,d   Botros, Hany Goubran ^a,b   Pagan, Cécile ^a,b   Périvier, Samuel ^d   Scheid, Isabelle ^a,b   Nygren, Gudrun ^e   Anckarsäter, Henrik ^e,f   Rastam, Maria ^g   Ståhlberg, Ola ^e   Gillberg, Carina ^e   Serrano, Emilie ^a,b   Lemiére, Nathalie ^a,b   Launay, Jean Marie ^h   Mouren Simeoni, Marie Christine ^d   Leboyer, Marion ^i,j   Gillberg, Christopher ^e,k   Jockers, Ralf ^c   Bourgeron, Thomas ^a,b,j,l   more..

^a INSTITUT PASTEUR   (France)

^b Institut Pasteur   (France)

^c INSTITUT COCHIN   (France)

^d HÔPITAL ROBERT DEBRÉ   (France)

^e UNIVERSITY OF GOTHENBURG   (Sweden)

^f LUND UNIVERSITY   (Sweden)

^g LUND UNIVERSITY   (Sweden)

^h HÔPITAL LARIBOISIÈRE   (France)

ⁱ UNIVERSITÉ PARIS EST CRÉTEIL   (France)

^j Fondation Fondamental   (France)

^k ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^l UNIVERSITÉ PARIS DESCARTES   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; HORMONE RECEPTOR; MELATONIN 1 RECEPTOR; MELATONIN 2 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN GPR50; UNCLASSIFIED DRUG; CYCLIC AMP; MAPK1 PROTEIN, HUMAN; MELATONIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

ADULT; ARTICLE; AUTISM; CHILD; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HORMONE BINDING; HUMAN; MAJOR CLINICAL STUDY; MALE; MUTANT; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CELL STRAIN COS1; CERCOPITHECUS; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; MUTATION;

ADULT; ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; CHILD; CHILD DEVELOPMENT DISORDERS, PERVASIVE; COS CELLS; CYCLIC AMP; FEMALE; HUMANS; MALE; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUTATION; RECEPTOR, MELATONIN, MT1; RECEPTOR, MELATONIN, MT2; RECEPTORS, MELATONIN;

EID: 77955389706     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011495     Document Type: Article

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