A novel synthesis of 3-aryl-2,6-dicyano-5-methylanilines via reaction between nitrostyrenes and malononitrile

Synthesis

Volumn , Issue 9, 2010, Pages 1526-1530

  Adib, Mehdi ^a   Mohammadi, Bagher ^a   Ansari, Samira ^a   Bijanzadeh, Hamid R ^b   Zhu, Long Guan ^c  

^a UNIVERSITY OF TEHRAN   (Iran)

^b TARBIAT MODARES UNIVERSITY   (Iran)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

2, 6 dicyanoanilines; Aromatics; Cyclizations; Nitrostyrenes; Regio selective

Indexed keywords

2 ,6-DICYANOANILINES; CYCLIZATIONS; GOOD YIELD; MALONONITRILES; REGIO-SELECTIVE; ROOM TEMPERATURE; SODIUM CARBONATE;

CYCLIZATION; ETHANOL; SODIUM; SYNTHESIS (CHEMICAL);

AROMATIZATION;

3 ARYL 2,6 DICYANO 5 METHYLANILINE DERIVATIVE; ALCOHOL; ANILINE DERIVATIVE; MALONONITRILE; NITROSTYRENE DERIVATIVE; SODIUM CARBONATE; STYRENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CYCLIZATION; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; PURIFICATION; REACTION TIME; ROOM TEMPERATURE; X RAY ANALYSIS;

EID: 77955356948     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/S-0029-1218717     Document Type: Article

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37. 1, 1579 observed reflections, final R1 = 0.058, wR2 = 0.150 and for all data R1 = 0.085, wR2 = 0.163. Crystallographic data for compound 2a have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication number CCDC 734566. Copies of these data can be obtained free of charge from the CCDC via www.ccdc.cam.ac.uk/data-request/cif.