Development of a 3D human in vitro skin co-culture model for detecting irritants in real-time

Biotechnology and Bioengineering

Volumn 106, Issue 5, 2010, Pages 794-803

  Canton I ^a   Cole, D M ^a   Kemp, E H ^a   Watson, P F ^a   Chunthapong, J ^a   Ryan, A J ^a   MacNeil, S ^a   Haycock, J W ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Fibroblast; In vitro models; Inflammation; Keratinocyte; Skin; Toxicity

Indexed keywords

CELL CULTURE; FIBROBLASTS; MATERIALS TESTING; PATHOLOGY; POTASSIUM; SODIUM; TISSUE; TOXICITY;

3D CULTURE; ANIMAL TESTING; CELL TYPES; COCULTURE; CONDITIONED MEDIUM; DIRECT INCUBATION; ENGINEERED MATERIALS; HUMAN FIBROBLAST; HUMAN KERATINOCYTES; IN-VITRO; IN-VIVO; INFLAMMATORY REACTION; INTERLEUKIN-1; KERATINOCYTE; KERATINOCYTES; MICRO-FIBER; PARACRINE; PARACRINE INTERACTIONS; SKIN TOXICITY; SODIUM DODECYL SULPHATE; TRANSFECTED CELLS;

THREE DIMENSIONAL;

DODECYL SULFATE SODIUM; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; POTASSIUM; POTASSIUM DIFORMATE; UNCLASSIFIED DRUG; IRRITANT AGENT;

3D IN VITRO SKIN COCULTURE; ARTICLE; CELL CULTURE; COCULTURE; CULTURE TECHNIQUE; CYTOTOXICITY; FIBROBLAST; FIBROBLAST CULTURE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INFLAMMATION; KERATINOCYTE; PARACRINE SIGNALING; TISSUE ENGINEERING; DRUG EFFECTS; METABOLISM; ORGAN CULTURE TECHNIQUE; REPORTER GENE; SKIN; TIME; TOXICITY;

CELL CULTURE TECHNIQUES; COCULTURE TECHNIQUES; FIBROBLASTS; GENES, REPORTER; HUMANS; IRRITANTS; KERATINOCYTES; NF-KAPPA B; ORGAN CULTURE TECHNIQUES; SKIN; TIME FACTORS;

EID: 77955351178     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22742     Document Type: Article

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