Neutralizing TIMP1 restores fecundity in a rat model of endometriosis and treating control rats with TIMP1 causes anomalies in ovarian function and embryo development

Biology of Reproduction

Volumn 83, Issue 2, 2010, Pages 185-194

  Stilley, Julie A W ^a,b   Birt, Julie A ^a,b   Nagel, Susan C ^a   Sutovsky, Miriam ^b   Sutovsky, Peter ^a,b   Sharpe Timms, Kathy L ^a,b  

^a University of Missouri   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

Embryo; Endometriosis; Infertility; Ovary; TIMP1

Indexed keywords

TISSUE INHIBITOR OF METALLOPROTEINASE 1; ANTIBODY; MATRIX METALLOPROTEINASE INHIBITOR; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS LUTEUM; DEVELOPMENTAL DISORDER; EMBRYO; EMBRYO DEVELOPMENT; ENDOMETRIOSIS; FEMALE; FEMALE INFERTILITY; FERTILITY; NONHUMAN; OVARY FOLLICLE; OVARY INSUFFICIENCY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; RAT; ANIMAL; ANTAGONISTS AND INHIBITORS; ASCITES FLUID; CHEMISTRY; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; EMBRYO CULTURE; INFERTILITY, FEMALE; METABOLISM; OVARY; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; ZYGOTE;

ANIMALS; ANTIBODIES; ASCITIC FLUID; CORPUS LUTEUM; DISEASE MODELS, ANIMAL; EMBRYO CULTURE TECHNIQUES; EMBRYONIC DEVELOPMENT; ENDOMETRIOSIS; FEMALE; INFERTILITY, FEMALE; MATRIX METALLOPROTEINASE INHIBITORS; OVARIAN FOLLICLE; OVARY; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TISSUE INHIBITOR OF METALLOPROTEINASE-1; ZYGOTE;

EID: 77955348912     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.109.083287     Document Type: Article

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