Toxicity of flow line, durafill VS, and Dycal to dental pulp cells: Effects of growth factors

Journal of Endodontics

Volumn 36, Issue 7, 2010, Pages 1149-1153

  Furey, Alyssa ^a   Hjelmhaug, Julie ^a   Lobner, Doug ^a  

^a MARQUETTE UNIVERSITY   (United States)

Author keywords

BMP 2; BMP 7; dental pulp; EGF; FGF 2; IGF I; pulp capping; TGF ; toxicity

Indexed keywords

6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID; ANTIOXIDANT; BENZYLOXYCARBONYLVALYL ALANYL ASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; BIOMEDICAL AND DENTAL MATERIALS; BMP2 PROTEIN, HUMAN; BMP7 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN 2; CALCIUM HYDROXIDE; CASPASE; CHROMAN DERIVATIVE; COLORING AGENT; DIAGNOSTIC AGENT; DYCAL; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; FLOWABLE HYBRID COMPOSITE; MINERAL; OSTEOGENIC PROTEIN 1; PEPTIDE CHLOROMETHYL KETONE; RESIN; SIGNAL PEPTIDE; SOMATOMEDIN C; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE; TRANSFORMING GROWTH FACTOR BETA; TROLOX C;

ADULT; ARTICLE; CELL CULTURE; CELL DEATH; CELL SURVIVAL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG TOLERANCE; DURAFILL; HUMAN; MATERIALS TESTING; OXIDATIVE STRESS; PHYSIOLOGY; TIME; TOOTH PULP;

ADULT; AMINO ACID CHLOROMETHYL KETONES; ANTIOXIDANTS; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 7; CALCIUM HYDROXIDE; CASPASES; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CHROMANS; COLORING AGENTS; COMPOSITE RESINS; DENTAL MATERIALS; DENTAL PULP; DRUG TOLERANCE; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MATERIALS TESTING; MINERALS; OXIDATIVE STRESS; TETRAZOLIUM SALTS; THIAZOLES; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 77955323575     PISSN: 00992399     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joen.2010.03.013     Document Type: Article

References (35)

1. Stanley HR. Pulp capping: conserving the dental pulp-can it be done? is it worth it? Oral Surg Oral Med Oral Pathol 1989;68:628-39.
2. Cox CF, Suzuki S. Re-evaluating pulp protection: calcium hydroxide liners vs cohesive hybridization. J Am Dent Assoc 1994;125:823-31.
3. Barthel CR, Rosenkranz B, Leuenberg A, Roulet JF. Pulp capping of carious exposures: treatment outcome after 5 and 10 years-a retrospective study. J Endod 2000;26:525-8.
4. Ward J. Vital pulp therapy in cariously exposed permanent teeth and its limitations. Aust Endod J 2002;28:29-37.
5. Goracci G, Mori G. Scanning electron microscopic evaluation of resin-dentin and calcium hydroxide-dentin interface with resin composite restorations. Quintessence Int 1996;27:129-35.
6. Weine FS. Alternatives to routine endodontic treatment. In: Weine FS, ed. Endodontic therapy. St Louis: Mosby; 2004:513-45.
7. Tziafas D, Smith AJ, Lesot H. Designing new treatment strategies in vital pulp therapy. J Dent 2000;28:77-92.
8. Tziafas D. The future role of a molecular approach to pulp-dentinal regeneration. Caries Res 2004;38:314-20.
9. Rutherford B, Fitzgerald M. A new biological approach to vital pulp therapy. Crit Rev Oral Biol Med 1995;6:218-29.
10. Bègue-Kirn C, Smith AJ, Loriot M, Kupferle C, Ruch JV, Lesot H. Comparative analysis of TGF beta s, BMPs, IGF1, msxs, fibronectin, osteonectin and bone sialoprotein gene expression during normal and in vitro-induced odontoblast differentiation. Int J Dev Biol 1994;38:405-20.
11. Saito T, Ogawa M, Hata Y, Bessho K. Acceleration effect of human recombinant bone morphogenetic protein-2 on differentiation of human pulp cells into odontoblasts. J Endod 2004;30:205-8.
12. Nadiri A, Kuchler-Bopp S, Haikel Y, Lesot H. Immunolocalization of BMP-2/-4, FGF-4, and WNT10b in the developing mouse first lower molar. J Histochem Cytochem 2004;52:103-12.
13. Nakashima M. Tissue engineering in endodontics. Aust Endod J 2005;31:111-3.
14. Helder MN, Karg H, Bervoets TJ, et al. Bone morphogenetic protein-7 (osteogenic protein-1, OP-1) and tooth development. J Dent Res 1998;77:545-54.
15. Goldberg M, Six N, Decup F, et al. Application of bioactive molecules in pulpcapping situations. Adv Dent Res 2001;15:91-5.
16. Sloan AJ, Rutherford RB, Smith AJ. Stimulation of the rat dentine-pulp complex by bone morphogenetic protein-7 in vitro. Arch Oral Biol 2000;45:173-7.
17. Russo LG, Maharajan P, Maharajan V. Basic fibroblast growth factor (FGF-2) in mouse tooth morphogenesis. Growth Factors 1998;5:125-33.
18. Nakao K, Itoh M, Tomita Y, Tomooka Y, Tsuji T. FGF-2 potently induces both proliferation and DSP expression in collagen type I gel cultures of adult incisor immature pulp cells. Biochem Biophys Res Commun 2004;325:1052-9.
19. Hao J, Wang P, Shi J. The effects of basic fibroblast growth factor on proliferation and differentiation of human dental pulp cells in vitro. Zhonghua kouqiang yixue zazhi (Chinese Journal of Stomatology) 1999;34:239-41.
20. Davideau JL, Sahlberg C, Blin C, Papagerakis P, Thesleff I, Berdal A. Differential expression of the full-length and secreted truncated forms of EGF receptor during formation of dental tissues. Int J Dev Biol 1995;39:39605-15.
21. Cobo J, Hernández LC, del Valle ME, Vijande M, Vega JA. Immunohistochemical localization of epidermal growth factor and its receptor during odontogenesis in the rat. Eur J Orthod 1992;14:333-8.
22. D'Souza RN, Happonen RP, Ritter NM, Butler WT. Temporal and spatial paterns of transforming growth factor-beta 1 expression in developing rat molars. Arch Oral Biol 1990;35:957-65.
23. Nie X, Tian W, Zhang Y, et al. Induction of transforming growth factor-beta 1 on dentine pulp cells in different culture patterns. Cell Biol Int 2006;30:295-300.
24. Onishi T, Kinoshita S, Shintani S, Sobue S, Ooshima T. Stimulation of proliferation and differentiation of dog dental pulp cells in serum-free culture medium by insulinlike growth factor. Arch Oral Biol 1999;44:361-71.
25. Lovschall H, Fejerskov O, Flyvbjerg A. Pulp-capping with recombinant human insulin-like growth factor I (rhIGF-I) in rat molars. Adv Dent Res 2001;15:108-12.
26. Rittenberg B, Moghadam HG, Sandor GKB, Clokie CML. Mandibular reconstruction with BMP-7: a prospective clinical study. Br J Oral Maxillofac Surg 2003;61: 92-3.
27. Khan SN, Lane JM. The use of recombinant human bone morphogenetic protein-2 (rhBMP-2) in orthopaedic applications. Expert Opin Biol Ther 2004;4:741-8.
28. Berlanga-Acosta J, Gavilondo-Cowley J, López-Saura P, et al. Epidermal growth factor in clinical practice-a review of its biological actions, clinical indications and safety implications. Int Wound J 2009;6:331-46.
29. Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Natl Acad Sci U S A 2000;97:13625-30.
30. Cabrera S, Barden D, Wolf M, Lobner D. Effects of growth factors on dental pulp cell sensitivity to amalgam toxicity. Dent Mater 2007;23:1205-10.
31. Lobner D. Comparison of the LDH and MTT assays for quantifying cell death: validity for neuronal apoptosis? J Neurosci Methods 2000;96:147-52.
32. Yasuda Y, Ogawa M, Arakawa T, Kadowaki T, Saito T. The effect of mineral trioxide aggregate on the mineralization ability of rat dental pulp cells: an in vitro study. J Endod 2008;34:1057-60.
33. Asrari M, Lobner D. In vitro neurotoxic evaluation of root-end-filling materials. J Endod 2003;29:743-6.
34. Roberts HW, Toth JM, Berzins DW, Charlton DG. Mineral trioxide aggregate material use in endodontic treatment: a review of the literature. Dent Mater 2008;24:149-64.
35. Mainwaring G, Foster JR, Lund V, Green T. Methyl methacrylate toxicity in rat nasal epithelium: studies of the mechanism of action and comparisons between species. Toxicology 2001;158:109-18.