Mutation specific drug therapy for progressive familial or benign recurrent intrahepatic cholestasis: A new tool in a near future?

Journal of Hepatology

Volumn 53, Issue 2, 2010, Pages 385-387

  Gonzales, Emmanuel ^a,b   Jacquemin, Emmanuel ^a,b  

^a BICÊTRE HOSPITAL   (France)

^b INSERM   (France)

Author keywords

ABCB11; ABCB4; ATP8B1; BRIC; BSEP; Chaperone drug; FIC1; MDR3; Nuclear receptor; PFIC; Stop codon skipping; Treatment

Indexed keywords

4 PHENYLBUTYRIC ACID; GENE PRODUCT; MESSENGER RNA; PROTEASOME; PROTEIN ATP8B1; UNCLASSIFIED DRUG;

AUTOSOMAL RECESSIVE INHERITANCE; BENIGN RECURRENT INTRAHEPATIC CHOLESTASIS TYPE 1; CELL MEMBRANE; DISEASE SEVERITY; DRUG EFFICACY; ENDOPLASMIC RETICULUM; FAMILIAL DISEASE; GENE EXPRESSION; GENE MUTATION; HUMAN; INTRAHEPATIC CHOLESTASIS; MISSENSE MUTATION; NONSENSE MUTATION; NOTE; PRIORITY JOURNAL; PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS TYPE 1; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN LOCALIZATION; RECURRENT DISEASE;

EID: 77955306048     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.03.012     Document Type: Note

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