Subdomain 3 of Plasmodium falciparum VAR2CSA DBL3x is identified as a minimal chondroitin sulfate A-binding region

Journal of Biological Chemistry

Volumn 285, Issue 32, 2010, Pages 24855-24862

  Singh, Kavita ^a   Gitti, Rossitza K ^b   Diouf, Ababacar ^a   Zhou, Hong ^a   Gowda, D Channe ^c   Miura, Kazutoyo ^a   Ostazeski, Stanley A ^b   Fairhurst, Rick M ^a   Garboczi, David N ^a   Long, Carole A ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b EDGEWOOD CHEMICAL BIOLOGICAL CENTER   (United States)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLOW CYTOMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

CHONDROITIN SULFATES; FLOW CYTOMETRY ANALYSIS; IN-VITRO; INFECTED ERYTHROCYTES; MOLECULAR BASIS; NMR SPECTROSCOPY; PARASITE-; PLASMODIUM FALCIPARUM; PREGNANT WOMAN; RECOMBINANT MOLECULES; SUB-DOMAINS; SUBDOMAIN;

PROTEINS;

CHONDROITIN 4 SULFATE; DUFFY BINDING PROTEIN; ERYTHROCYTE MEMBRANE PROTEIN 1; UNCLASSIFIED DRUG; VAR2CSA PROTEIN; CHONDROITIN SULFATE; PARASITE ANTIGEN; PROTEIN BINDING; VAR2CSA PROTEIN, PLASMODIUM FALCIPARUM;

ANIMAL CELL; ARTICLE; BINDING SITE; CHO CELL; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENDEMIC DISEASE; FEMALE; FLOW CYTOMETRY; HUMAN; MALARIA; MALARIA FALCIPARUM; MUTATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PLASMODIUM FALCIPARUM; PREGNANCY ASSOCIATED MALARIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; ANIMAL; CHEMISTRY; CHO CELL LINE; CRICETULUS; ERYTHROCYTE; HAMSTER; METABOLISM; PARASITOLOGY; PHYSIOLOGY; PREGNANCY; PREGNANCY COMPLICATION; PROCEDURES; PROTEIN FOLDING;

ANIMALS; ANTIGENS, PROTOZOAN; CHO CELLS; CHONDROITIN SULFATES; CRICETINAE; CRICETULUS; ERYTHROCYTES; FEMALE; FLOW CYTOMETRY; HUMANS; PLASMODIUM FALCIPARUM; PREGNANCY; PREGNANCY COMPLICATIONS, PARASITIC; PROTEIN BINDING; PROTEIN FOLDING;

EID: 77955297219     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.118612     Document Type: Article

References (39)

1. Brabin, B. J., Romagosa, C., Abdelgalil, S., Menéndez, C., Verhoeff, F. H., McGready, R., Fletcher, K. A., Owens, S., D'Alessandro, U., Nosten, F., Fischer, P. R., and Ordi, J. (2004) Placenta 25, 359-378
2. Salanti, A., Staalsoe, T., Lavstsen, T., Jensen, A. T., Sowa, M. P., Arnot, D. E., Hviid, L., and Theander, T. G. (2003) Mol. Microbiol. 49, 179-191
3. Trimnell, A. R., Kraemer, S. M., Mukherjee, S., Phippard, D. J., Janes, J. H., Flamoe, E., Su, X. Z., Awadalla, P., and Smith, J. D. (2006) Mol. Biochem. Parasitol. 148, 169-180
4. Rowe, J. A., Kyes, S. A., Rogerson, S. J., Babiker, H. A., and Raza, A. (2002) J. Infect. Dis. 185, 1207-1211
5. Fried, M., Hixson, K. K., Anderson, L., Ogata, Y., Mutabingwa, T. K., and Duffy, P. E. (2007) Mol. Biochem. Parasitol. 155, 57-65
6. Viebig, N. K., Gamain, B., Scheidig, C., Lépolard, C., Przyborski, J., Lanzer, M., Gysin, J., and Scherf, A. (2005) EMBO Rep. 6, 775-781
7. Duffy, M. F., Maier, A. G., Byrne, T. J., Marty, A. J., Elliott, S. R., O'Neill, M. T., Payne, P. D., Rogerson, S. J., Cowman, A. F., Crabb, B. S., and Brown, G. V. (2006) Mol. Biochem. Parasitol. 148, 117-124
8. Fried, M., and Duffy, P. E. (1998) J. Mol. Med. 76, 162-171
9. Maubert, B., Fievet, N., Tami, G., Cot, M., Boudin, C., and Deloron, P. (1999) Infect. Immun. 67, 5367-5371
10. Beeson, J. G., Mann, E. J., Byrne, T. J., Caragounis, A., Elliott, S. R., Brown, G. V., and Rogerson, S. J. (2006) J. Infect. Dis. 193, 721-730
11. Ricke, C. H., Staalsoe, T., Koram, K., Akanmori, B. D., Riley, E. M., Theander, T. G., and Hviid, L. (2000) J. Immunol. 165, 3309-3316
12. Hviid, L. (2010) Hum. Vaccin. 6, 84-89
13. Gamain, B., Trimnell, A. R., Scheidig, C., Scherf, A., Miller, L. H., and Smith, J. D. (2005) J. Infect Dis. 191, 1010-1013
14. Avril, M., Gamain, B., Lépolard, C., Viaud, N., Scherf, A., and Gysin, J. (2006) Microbes Infect. 8, 2863-2871
15. Singh, K., Gittis, A. G., Nguyen, P., Gowda, D. C., Miller, L. H., and Garboczi, D. N. (2008) Nat. Struct. Mol. Biol. 15, 932-938
16. Higgins, M. K. (2008) J. Biol. Chem. 283, 21842-21846
17. Achur, R. N., Valiyaveettil, M., and Gowda, D. C. (2003) J. Biol. Chem. 278, 11705-11713
18. Alkhalil, A., Achur, R. N., Valiyaveettil, M., Ockenhouse, C. F., and Gowda, D. C. (2000) J. Biol. Chem. 275, 40357-40364
19. Fried, M., Lauder, R. M., and Duffy, P. E. (2000) Exp. Parasitol. 95, 75-78
20. Chai, W., Beeson, J. G., and Lawson, A. M. (2002) J. Biol. Chem. 277, 22438-22446
21. Sodeoka, M., Larson, C. J., Chen, L., LeClair, K. P., and Verdine, G. L. (1993) Bioorg. Med. Chem. Lett. 3, 1089-1094
22. Gamain, B., Miller, L. H., and Baruch, D. I. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 2664-2669
23. Mayer, M., and Meyer, B. (2001) J. Am. Chem. Soc. 123, 6108-6117
24. Clore, G. M., Gronenborn, A. M., Mitchinson, C., and Green, N. M. (1982) Eur. J. Biochem. 128, 113-117
25. Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J., and Bax, A. (1995) J. Biomol. NMR 6, 277-293
26. Toida, T., Toyoda, H., and Imanari, T. (1993) Analytical Sciences 9, 53-58
27. Miura, K., Orcutt, A. C., Muratova, O. V., Miller, L. H., Saul, A., and Long, C. A. (2008) Vaccine 26, 193-200
28. Tan, K., Duquette, M., Liu, J. H., Zhang, R., Joachimiak, A., Wang, J. H., and Lawler, J. (2006) Structure 14, 33-42
29. Tan, K., Duquette, M., Liu, J. H., Shanmugasundaram, K., Joachimiak, A., Gallagher, J. T., Rigby, A. C., Wang, J. H., and Lawler, J. (2008) J. Biol. Chem. 283, 3932-3941
30. Khunrae, P., Philip, J. M., Bull, D. R., and Higgins, M. K. (2009) J. Mol. Biol. 393, 202-213
31. Dahlbäck, M., Rask, T. S., Andersen, P. H., Nielsen, M. A., Ndam, N. T., Resende, M., Turner, L., Deloron, P., Hviid, L., Lund, O., Pedersen, A. G., Theander, T. G., and Salanti, A. (2006) PLoS Pathog. 2, e124
32. Blanchard, V., Chevalier, F., Imberty, A., Leeflang, B. R., Basappa, Sugahara, K., and Kamerling, J. P. (2007) Biochemistry 46, 1167-1175
33. Glaudemans, C. P., Lerner, L., Daves, G. D., Jr., Kovác, P., Venable, R., and Bax, A. (1990) Biochemistry 29, 10906-10911
34. Scherf, T., and Anglister, J. (1993) Biophys. J. 64, 754-761
35. Cosman, M., Krishnan, V. V., and Balhorn, R. (2005) Methods Mol. Biol. 300, 141-163
36. Khunrae, P., Dahlbäck, M., Nielsen, M. A., Andersen, G., Ditlev, S. B., Resende, M., Pinto, V. V., Theander, T. G., Higgins, M. K., and Salanti, A. (2010) J. Mol. Biol. 397, 826-834
37. Srivastava, A., Gangnard, S., Round, A., Dechavanne, S., Juillerat, A., Raynal, B., Faure, G., Baron, B., Ramboarina, S., Singh, S. K., Belrhali, H., England, P., Lewit-Bentley, A., Scherf, A., Bentley, G. A., and Gamain, B. (2010) Proc. Natl. Acad. Sci. U.S.A. 107, 4884-4889
38. Salanti, A., Resende, M., Ditlev, S. B., Pinto, V. V., Dahlbäck, M., Andersen, G., Manczak, T., Theander, T. G., and Nielsen, M. A. (2010) Malar. J. 9, 11
39. Nielsen, M. A., Pinto, V. V., Resende, M., Dahlbäck, M., Ditlev, S. B., Theander, T. G., and Salanti, A. (2009) Infect. Immun. 77, 2482-2487