Metabolic imaging in the anesthetized rat brain using hyperpolarized [1-13C] pyruvate and [1-13C] ethyl pyruvate

Magnetic Resonance in Medicine

Volumn 63, Issue 5, 2010, Pages 1137-1143

  Hurd, Ralph E ^a   Yen, Yi Fen ^a   Mayer, Dirk ^b,c   Chen, Albert ^a   Wilson, David ^d   Kohler, Susan ^e   Bok, Robert ^d   Vigneron, Daniel ^d   Kurhanewicz, John ^d   Tropp, James ^a   Spielman, Daniel ^b   Pfefferbaum, Adolf ^b,c  

^a GE HEALTHCARE   (United States)

^b STANFORD UNIVERSITY   (United States)

^c SRI INTERNATIONAL   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNION COLLEGE   (United States)

Author keywords

Brain; Carbon 13; Ethyl pyruvate; Hyperpolarized; Lactate; Pyruvate

Indexed keywords

BRAIN; METABOLISM; RANGE FINDING; RATS;

CARBON-13; ETHYL PYRUVATE; HYPERPOLARIZED; LACTATE; PYRUVATES;

SPIN POLARIZATION;

CARBON 13; ETHYL PYRUVIC ACID; PYRUVIC ACID; PYRUVIC ACID DERIVATIVE; UNCLASSIFIED DRUG; ANESTHETIC AGENT; CARBON; DIAGNOSTIC AGENT; PYRUVIC ACID ETHYL ESTER;

ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN METABOLISM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG UPTAKE; FEASIBILITY STUDY; HYPERPOLARIZATION; MALE; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; RAT; SPECTROSCOPY; ANIMAL; BRAIN; DRUG EFFECT; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TISSUE DISTRIBUTION; WISTAR RAT;

ANESTHETICS, GENERAL; ANIMALS; BRAIN; CARBON ISOTOPES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; PYRUVATES; PYRUVIC ACID; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

EID: 77955294061     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.22364     Document Type: Article

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