Is epicardial fat tissue a marker of metabolic syndrome in obese children?

Atherosclerosis

Volumn 211, Issue 2, 2010, Pages 596-600

  Mazur, Artur ^a   Ostański, Mariusz ^a   Telega, Grzegorz ^b   Malecka Tendera, Ewa ^c  

^a UNIVERSITY OF RZESZÓW   (Poland)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

Children; Epicardial fat; Metabolic syndrome; Obesity

Indexed keywords

GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADOLESCENT; ARTICLE; BODY MASS; CHILD; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; EPICARDIUM; FEMALE; HUMAN; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; OBESITY; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE; WAIST CIRCUMFERENCE;

ADIPOSE TISSUE; ADOLESCENT; BIOLOGICAL MARKERS; BODY MASS INDEX; CHILD; DIASTOLE; FEMALE; HEART VENTRICLES; HUMANS; INSULIN RESISTANCE; MALE; METABOLIC SYNDROME X; OBESITY; PERICARDIUM; SYSTOLE;

EID: 77955278431     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2010.02.036     Document Type: Article

References (30)

1. Matsuzawa Y., Funahashi T., Nakamura T. Molecular mechanism of metabolic syndrome X: contribution of adipocytokines adipocyte-derived bioactive substances. Ann NY Acad Sci 1999, 892:146-154.
2. Marchington J.M., Mattacks C.A., Pond C.M. Adipose tissue in the mammalian heart and pericardium: structure, fetal development and biochemical properties. Comp Biochem Physiol 1989, 94:225-232.
3. Corradi D., Maestri R., Callegari S., et al. The ventricular epicardial fat is related to the myocardial mass in normal, ischemic and hypertrophic hearts. Cardiovasc Pathol 2004, 13:313-316.
4. Manzella D., Barbieri M., Rizzo M.R., et al. Role of free fatty acids on cardiac autonomic nervous system in noninsulin-dependent diabetic patients: effects of metabolic control. J Clin Endocrinol Metab 2001, 86:2769-2774.
5. Mazurek T., Zhang L., Zalewski A., Mannion J.D., et al. Diabetes-induced oxidative stress and low-grade inflammation in porcine coronary arteries. Circulation 2003, 108:2460-2466.
6. Iacobellis G., Pistilli D., Gucciardo M., et al. Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease. Cytokine 2005, 29:251-255.
7. Kalra D.K., Zhu X., Ramchandani M.K., Lawrie G., et al. Increased myocardial gene expression of tumor necrosis factor alpha and nitric oxide synthase-2: a potential mechanism for depressed myocardial function in hibernating myocardium in humans. Circulation 2002, 105:1537-1540.
8. Iacobellis G., Barbaro G., Gerstein H.C. Relationship of epicardial fat thickness and fasting glucose. Int J Cardiol 2008, 128:424-426.
9. Iacobellis G., Gao Y.J., Sharma A.M. Do cardiac and perivascular adipose tissue play a role in atherosclerosis?. Curr Diab Rep 2008, 8:20-24.
10. Bokor S., Frelut M.L., Vania A., et al. Prevalence of metabolic syndrome in European children. Int J Pediatr Obes 2008, (Suppl 2):3-8.
11. Cole T.J., Bellizzi M.C., Flegal K.M., Dietz W.H. Establishing a standard definition for child overweight and obesity worldwide international survey. BMJ 2000, 320:1240-1243.
12. World Health Organization. Physical status: the use and interpretation of anthropometry: a report of a WHO expert committee. Geneva: WHO 1995.
13. European Society of Hypertension Working Group on Blood Pressure MonitoringO'Brien E, Asma R, Beilin L, et al. J Hypertension 2003;21:821-848.
14. Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972, 18:499-502.
15. Matthews D.R., Hosker J.P., Rudenski A.S., et al. Homeostasis model assessment: insulin resistance and ß-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28:412-419.
16. Zimmet P., Alberti K.G., Kaufman F., et al. The metabolic syndrome in children and adolescents - an IDF consensus report. Pediatr Diabetes 2007, 8:299-306.
17. Iacobellis G., Assael F., Ribaudo M.C., et al. Epicardial fat from echocardiography: a new method for visceral adipose tissue prediction. Obes Res 2003, 11:304-310.
18. Iacobellis G., Ribando M.C., Assal F., et al. Epicardial adipose tissue is related to anthropometric and clinical parameters of metabolic syndrome: a new indicator of cardiovascular risk. J Clin Endocrinol Metab 2003, 88:5163-5168.
19. Malavazos A.E., Ermetici F., Coman C., Corsi M.M., Morricone L., Ambrosi B. Influence of epicardia adipose tissue and adipocytokine levels on cardiac abnormalities in visceral obesity. Int J Cardiol 2007, 121:132-134.
20. Kessels K., Cramer M.J., Veldhuis B. Epicardial adipose tissue imaged by magnetic resonance imaging: an important risk marker of cardiovascular disease. Heart 2006, 92:262.
21. Mahabadi A.A., Massaro J.M., Rosito G.A., et al. Association of pericardial fat, intrathoracic fat, and visceral abdominal fat with cardiovascular disease burden: the Framingham Heart Study. Eur Heart J 2009, 30:850-856.
22. Baker A., da Silva N.F., Quinn D.W., et al. Human epicardial tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease. Cardiovas Diabetol 2006, 5:1-7.
23. Fernández J.R., Redden D.T., Pietrobelli A., Allison D.B. Waist circumference percentiles in nationally representative samples of African-American, European-American, and Mexican-American children and adolescents. J Pediatr 2004, 145:439-444.
24. Savva S.C., Tornaritis M., Savva M.E., et al. Waist circumference and waist-to-height ratio are better predictors of cardiovascular disease risk factors in children than body mass index. Int J Obes 2000, 24:1453-1458.
25. Syme C., Abrahamowicz M., Leonard G.T., et al. Intra-abdominal adiposity and individual components of metabolic syndrome in adolescence. Arch Pediatr Adolesc Med 2008, 162:453-461.
26. Abaci A., Tascilar M.E., Sarita T., et al. Threshold value of subepicardial adipose tissue to detect insulin resistance in obese children. Int J Obes 2009, 33:440-446.
27. Lanes R., Soros A., Flores K., et al. Endothelial function, carotid artery intima-media thickness, epicardial adipose tissue and left ventricular mass and function in growth hormone-deficient adolescents: apparent effects of growth hormone treatment on these parameters. J Clin Endocrinol Metab 2005, 90:3978-3982.
28. Ahn S.G., Lim H.S., Joe D.Y., et al. Relationship of epicardial adipose tissue by echocardiography to coronary artery disease. Heart 2008, 94:7-13.
29. Mazurek T., Zhang L., Zalewski A., et al. Human epicardial adipose tissue is a source of inflammatory mediators. Circulation 2003, 108:2460-2466.
30. Okyay K., Balcioglu A.S.A., Tavil Y., Yacoy G., Torkoglu S., Abaci A. A relationship between echocardiographic subepicardial adipose tissue and metabolic syndrome. Int J Cardiac Imaging 2008, 24:577-583.