Large conductance Ca2+-activated K+ channels inhibit vagal acetylcholine release at the rabbit sinoatrial node

Autonomic Neuroscience: Basic and Clinical

Volumn 156, Issue 1-2, 2010, Pages 149-151

  Kawada, Toru ^a   Akiyama, Tsuyoshi ^a   Shimizu, Shuji ^a   Kamiya, Atsunori ^a   Uemura, Kazunori ^a   Sata, Yusuke ^a   Shirai, Mikiyasu ^a   Sugimachi, Masaru ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Acetylcholine; Cardiac microdialysis; Rabbits; Vagal stimulation

Indexed keywords

IBERIOTOXIN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; ACETYLCHOLINE; HEXAMETHONIUM; PEPTIDE; POTASSIUM CHANNEL BLOCKING AGENT;

ACETYLCHOLINE RELEASE; ANIMAL CELL; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; EFFERENT NERVE; ELECTROSTIMULATION; HEART RIGHT ATRIUM; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; SINUS NODE; VAGUS NERVE; ANIMAL; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; PHYSIOLOGY; RABBIT; SECRETION;

ACETYLCHOLINE; ANIMALS; HEXAMETHONIUM; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; PEPTIDES; POTASSIUM CHANNEL BLOCKERS; RABBITS; SINOATRIAL NODE; VAGUS NERVE;

EID: 77955277212     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autneu.2010.04.003     Document Type: Article

References (8)

1. Abramochkin D.V., Nurullin L.F., Borodinova A.A., Tarasova N.V., Sukhova G.S., Nikolsky E.E., Rosenshtraukh L.V. Non-quantal release of acetylcholine from parasympathetic nerve terminals in the right atrium of rats. Exp. Physiol. 2010, 95(2):265-273.
2. + channels in catecholamine release from in vivo rat adrenal medulla. Neurochem. Int. 2010, 56:263-269.
3. Akiyama T., Yamazaki T., Ninomiya I. In vivo detection of endogenous acetylcholine release in cat ventricles. Am. J. Physiol. 1994, 266(3 Pt 2):H854-H860.
4. Glantz S.A. Primer of Biostatistics 2002, McGraw-Hill, New York. 5th ed.
5. Ledoux J., Werner M.E., Brayden J.E., Nelson M.T. Calcium-activated potassium channels and the regulation of vascular tone. Physiol. 2006, 21:69-79.
6. Meade C.J. The mechanism by which epinastine stops an adenosine analog from contracting BDE rat airways. Am. J. Respir. Crit. Care Med. 1998, 157:522-530.
7. + channel function in rat dorsal vagal neurones. J. Physiol. 2000, 527:283-290.
8. Shimizu S., Akiyama T., Kawada T., Shishido T., Yamazaki T., Kamiya A., Mizuno M., Sano S., Sugimachi M. In vivo direct monitoring of vagal acetylcholine release to the sinoatrial node. Auton. Neurosci. 2009, 148:44-49.