Covalently immobilized RGD gradient on PEG hydrogel scaffold influences cell migration parameters

Acta Biomaterialia

Volumn 6, Issue 7, 2010, Pages 2532-2539

  Guarnieri, D ^a   De Capua, A ^a   Ventre, M ^a   Borzacchiello, A ^b   Pedone, C ^c   Marasco, D ^c   Ruvo, M ^c   Netti, P A ^a  

^a ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Biological cues; Cell instructive materials; Cell migration; Hydrogels; Signal gradients

Indexed keywords

BIOMATERIALS; BIOMECHANICS; CELL ADHESION; CELL CULTURE; CELL PROLIFERATION; PEPTIDES; POLYETHYLENE GLYCOLS; SCAFFOLDS (BIOLOGY);

BIOLOGICAL CUE; CELL ACTIVITY; CELL INSTRUCTIVE MATERIAL; CELL MIGRATION; CELL RESPONSE; HYDROGEL SCAFFOLDS; MIGRATION PARAMETERS; RGD PEPTIDE; SIGNAL GRADIENT; UNIFORM DISTRIBUTION;

HYDROGELS;

ACRYLIC ACID DERIVATIVE; ARGINYLGLYCYLASPARTIC ACID; BIOMATERIAL; MACROGOL; ARGINYL-GLYCYL-ASPARTIC ACID; MACROGOL DERIVATIVE; OLIGOPEPTIDE;

ANIMAL CELL; ANIMAL TISSUE; ANISOTROPY; ARTICLE; CELL ACTIVITY; CELL ADHESION; CELL FUNCTION; CELL MIGRATION; CELL POPULATION; CONTROLLED STUDY; COVALENT BOND; HYDROGEL; IMMOBILIZED CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; TISSUE ENGINEERING; CELL MOTION; CHEMISTRY;

CELL MOVEMENT; HYDROGELS; OLIGOPEPTIDES; POLYETHYLENE GLYCOLS;

EID: 77955271320     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2009.12.050     Document Type: Article

References (47)

1. Lutolf MP, Hubbell JA. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat Biotechnol 2005;23(1):47-55 [Review].
2. Sands RW, Mooney DJ. Polymers to direct cell fate by controlling the microenvironment. Curr Opin Biotechnol 2007;18(5):448-53 [Review].
3. Cao L, Mooney DJ. Spatiotemporal control over growth factor signaling for therapeutic neovascularization. Adv Drug Deliv Rev 2007;59(13):1340-50 [Review].
4. Plummer ST, Wang Q, Bohn PW, Stockton R, Schwartz MA. Electrochemically derived gradients of the extracellular matrix protein fibronectin on gold. Langmuir 2003;19:7528-36.
5. Singhvi R, Kumar A, Lopez GP, Stephanopoulous GN, Wang DI, Whitesides GM, et al. Engineering cell shape and function. Science 1994;264:696-8.
6. Mrksich M. A surface chemistry approach to studying cell adhesion. Chem Soc Rev 2000;29:267-73.
7. Chen G, Ito Y. Gradient micropattern immobilization of EGF to investigate the effect of artificial juxtacrine stimulation. Biomaterials 2001;22:2453-7.
8. Ito Y, Hayashi M, Imanish Y. Gradient micropattern immobilization of heparin and its interaction with cells. J Biomater Sci Polym Ed 2001;12:367-78.
9. Zhu B, Eurell T, Gunawan R, Leckband D. Chain-length dependence of the protein and cell resistance of oligo (ethylene glycol)-terminated self-assembled monolayers on gold. J Biomed Mater Res 2001;56(3):406-16.
10. Adams DN, Kao EYC, Hypolite CL, Distefano MD, Hu WS, Letourneau PC. Growth cones turn and migrate up an immobilized gradient of the laminin IKVAV peptide. J Neurobiol 2005;62:134-47.
11. Kang CE, Gemeinhart EJ, Gemeinhart RA. Cellular alignment by grafted adhesion peptide surface density gradients. J Biomed Mater Res A 2004;71:403-11.
12. Bhangale SM, Tjong V, Wu L, Yakovlev N, Moran PM. Biologically active protein gradients via microstamping. Adv Mater 2005;17:809-13.
13. Jeon NL, Dertinger SKW, Chiu DT, Choi IS, Stroock AD, Whitesides GM. Generation of solution and surface gradients using microfluidic systems. Langmuir 2000;16:8311-6.
14. Burdick JA, Khademhosseini A, Langer R. Fabrication of gradient hydrogels using a microfluidics/photopolymerization process. Langmuir 2004;20(13):5153-6.
15. Boyden S. The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes. J Exp Med 1962;115:453-66.
16. Nelson RD, Quie PG, Simmons RL. Chemotaxis under agarose: a new and simple method for measuring chemotaxis and spontaneous migration of human polymorphonuclear leucocytes and monocytes. J Immunol 1975;115:1650-6.
17. Moghe PV, Nelson RD, Tranquillo RT. Cytokine-stimulated chemotaxis of human neutrophils in a 3-D conjoined fibrin gel assay. J Immunol Methods 1995;180:193-211.
18. Knapp DM, Helou EF, Tranquillo RT. A fibrin or collagen gel assay for tissue cell chemotaxis: assessment of fibroblast chemotaxis to RGDSP. Exp Cell Res 1999;247:543-53.
19. Smith JT, Tomfohr JK, Wells MC, Beebe TP, Kepler TB, Reichert WM. Measurement of cell migration on surface-bound fibronectin gradients. Langmuir 2004;20:8279-86.
20. De Long SA, Moon JJ, West JL. Covalently immobilized gradients of bFGF on hydrogel scaffolds for directed cell migration. Biomaterials 2005;26(16):3227-34.
21. De Long SA, Gobin AS, West JL. Covalent immobilization of RGDS on hydrogel surfaces to direct cell alignment and migration. Journal of Controlled Release 2005;109:139-48.
22. Smith JT, Elkin JT, Reichert WM. Directed cell migration on fibronectin gradients: effect of gradient slope. Exp Cell Res 2006;312(13):2424-32.
23. Kipper MJ, Kleinman HK, Wang FW. Covalent surface chemistry gradients for presenting bioactive peptides. Anal Biochem 2007;363(2):175-84.
24. Brandley BK, Schnaar RL. Tumor cell haptotaxis on covalently immobilized linear and exponential gradients of a cell adhesion peptide. Dev Biol 1989;135(1):74-86.
25. Mosesson MW, Siebenlist KR, Meh DA. The structure and biological features of fibrinogen and fibrin. Ann NY Acad Sci 2001;936:11-30.
26. Van Hinsbergh VW, Collen A, Koolwijk P. Role of the fibrin matrix in angiogenesis. Ann NY Acad Sci 2001;936:426-37.
27. Hubbell JA. Bioactive biomaterials. Curr Opin Biotechnol 1999;10(2):123-9 [Review].
28. Elbert DL, Hubbell JA. Conjugate addition reactions combined with free-radical cross-linking for the design of materials for tissue engineering. Biomacromolecules 2001;2(2):430-41.
29. Lutolf MP, Hubbell JA. Synthesis and physicochemical characterization of endlinked poly (ethylene glycol)-co-peptide hydrogels formed by Michael-type addition. Biomacromolecules 2003;4(3):713-22.
30. Bryant SJ, Nicodemus GD, Villanueva I. Designing 3D photopolymer hydrogels to regulate biomechanical cues and tissue growth for cartilage tissue engineering. Pharm Res 2008;25(10):2379-86.
31. Hern DL, Hubbell JA. Incorporation of adhesion peptides into nonadhesive hydrogels useful for tissue resurfacing. J Biomed Mater Res 1998;39:266-76.
32. Stokes CL, Lauffenburger DA, Williams SK. Migration of individual microvessel endothelial cells: stochastic model and parameter measurement. J Cell Sci 1991;99:419-30.
33. Tranquillo RT. Chemotactic movement of single cells. ASGSB Bull 1991;4(2):75-85 [Review].
34. Kipper MJ, Kleinman HK, Wang FW. New method for modeling connectivetissue cell migration: improved accuracy on motility parameters. Biophys J 2007;93(5):1797-808.
35. Sarvestani AS, Jabbari E. Analysis of cell locomotion on ligand gradient substrates. Biotechnol Bioeng 2009;103:424-9.
36. Fields GB, Noble RL. Solid phase peptide synthesis utilizing 9-fluorenylmethoxy-carbonil amino acids. Int J Pept Protein Res 1990;35:161-214.
37. Dickinson RB, Tranquillo RT. Optimal estimation of cell movement indices from the statistical analysis of cell tracking data. AIChE J 1993;39:1995-2010.
38. Walmod PS, Hartmann-Petersen R, Berezin A, Prag S, Kiselyov VV, Berezin V, et al. Evaluation of individual-cell motility. Methods Mol Biol 2001;161:59-83.
39. Brandley BK, Schnaar RL. Covalent attachment of an Arg-Gly-Asp sequence peptide to derivatizable polyacrylamide surfaces: support of fibroblast adhesion and long-term growth. Anal Biochem 1988;172(1):270-8.
40. Mann BK, Gobin AS, Tsai AT, Schmedlen RH, West JL. Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: synthetic ECM analogs for tissue engineering. Biomaterials 2001;22:3045-51.
41. Massia SP, Hubbell JA. An RGD spacing of 440 nm is sufficient for integrin alpha V beta 3 mediated fibroblast spreading and 140 nm for focal contact and stress fiber formation. J Cell Biol 1991;114(5):1089-100.
42. Irvine DJ, Hue KA, Mayes AM, Griffith LG. Simulations of cell-surface integrin binding to nanoscale-clustered adhesion ligands. Biophys J 2002;82:120-32.
43. Dunn GA. Characterising a kinesis response: time averaged measures of cell speed and directional persistence. Agents Actions Suppl 1983;12:14-33.
44. Codling EA, Plank MJ, Benhamou S. Random walk models in biology. J R Soc Interface 2008;5:813-34.
45. Di Milla PA, Barbee K, Lauffenburger DA. Mathematical model for the effects of adhesion and mechanics on cell migration speed. Biophys J 1991;60(1):15-37.
46. Maheshwari G, Lauffenburger DA. Deconstructing (and reconstructing) cell migration. Microsc Res Tech 1998;43:358-68.
47. Distasi C, Ariano P, Zamburlin P, Ferraro M. In vitro analysis of neuron-glial cell interactions during cellular migration. Eur Biophys J 2002;31:81-8.