Osteoclastogenesis in peripheral blood mononuclear cell cultures of periprosthetic osteolysis patients and the phenotype of T cells localized in periprosthetic tissues

Biomaterials

Volumn 31, Issue 29, 2010, Pages 7519-7525

  Roato, Ilaria ^a   Caldo, Davide ^a,b   D'Amico, Lucia ^a   D'Amelio, Patrizia ^c   Godio, Laura ^a   Patanè, Salvatore ^a   Astore, Franco ^d   Grappiolo, Guido ^d   Boggio, Maurizio ^e   Scagnelli, Roberto ^f   Molfetta, Luigi ^b   Ferracini, Riccardo ^a  

^a AOU San Giovanni Battista   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^e UNIVERSITY OF GENOA   (Italy)

^f Saluzzo Hospital Saluzzo   (Italy)

Author keywords

Arthroplasty; Osteoclast; Periprosthetic osteolysis; Spontaneous osteoclastogenesis; T cell

Indexed keywords

ARTHROPLASTIES; ASEPTIC LOOSENING; CITOMETRY; HEALTHY CONTROLS; IMMUNOHISTOCHEMISTRY; MEDICAL PROCEDURES; OSTEOCLASTOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELLS; PERIPROSTHETIC OSTEOLYSIS; T CELLS;

ABERRATIONS; BLOOD; CELLS; HISTOLOGY; TISSUE;

CELL CULTURE;

RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B;

AGED; ARTICLE; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL CULTURE; CELL INTERACTION; CELL ISOLATION; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; PROSTHESIS; T CELL DEPLETION;

ARTHROPLASTY, REPLACEMENT, HIP; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LEUKOCYTES, MONONUCLEAR; OSTEOCLASTS; OSTEOLYSIS; T-LYMPHOCYTES;

EID: 77955270888     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.06.027     Document Type: Article

References (26)

1. Felson D.T., Lawrence R.C., Dieppe P.A., Hirsch R., Helmick C.G., Jordan J.M., et al. Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med 2000, 133:635-646.
2. Arthursson A.J., Furnes O., Espehaug B., Havelin L.I., Soreide J.A. Prosthesis survival after total hip arthroplasty-does surgical approach matter? analysis of 19,304 Charnley and 6,002 exeter primary total hip arthroplasties reported to the Norwegian Arthroplasty Register. Acta Orthop 2007, 78:719-729.
3. Fehring T.K., Christie M.J., Lavernia C., Mason J.B., McAuley J.P., MacDonald S.J., et al. Revision total knee arthroplasty: planning, management, and controversies. Instr Course Lect 2008, 57:341-363.
4. Maloney W.J., Smith R.L. Periprosthetic osteolysis in total hip arthroplasty: the role of particulate wear debris. Instr Course Lect 1996, 45:171-182.
5. Goodman S.B. Wear particles, periprosthetic osteolysis and the immune system. Biomaterials 2007, 28:5044-5048.
6. Abu-Amer Y., Darwech I., Clohisy J.C. Aseptic loosening of total joint replacements: mechanisms underlying osteolysis and potential therapies. Arthritis Res Ther 2007, 9(Suppl. 1):S6.
7. Roato I., Grano M., Brunetti G., Colucci S., Mussa A., Bertetto O., et al. Mechanisms of spontaneous osteoclastogenesis in cancer with bone involvement. Faseb J 2005, 19:228-230.
8. Arora A., Song Y., Chun L., Huie P., Trindade M., Smith R.L., et al. The role of the TH1 and TH2 immune responses in loosening and osteolysis of cemented total hip replacements. J Biomed Mater Res A 2003, 64:693-697.
9. Baldwin L., Flanagan B.F., McLaughlin P.J., Parkinson R.W., Hunt J.A., Williams D.F. A study of tissue interface membranes from revision accord knee arthroplasty: the role of T lymphocytes. Biomaterials 2002, 23:3007-3014.
10. Farber A., Chin R., Song Y., Huie P., Goodman S. Chronic antigen-specific immune-system activation may potentially be involved in the loosening of cemented acetabular components. J Biomed Mater Res 2001, 55:433-441.
11. Li T.F., Santavirta S., Waris V., Lassus J., Lindroos L., Xu J.W., et al. No lymphokines in T-cells around loosened hip prostheses. Acta Orthop Scand 2001, 72:241-247.
12. Granchi D., Ciapetti G., Savarino L., Stea S., Filippini F., Sudanese A., et al. Expression of the CD69 activation antigen on lymphocytes of patients with hip prosthesis. Biomaterials 2000, 21:2059-2065.
13. Hallab N.J., Anderson S., Stafford T., Glant T., Jacobs J.J. Lymphocyte responses in patients with total hip arthroplasty. J Orthop Res 2005, 23:384-391.
14. Kiesel J.R., Buchwald Z.S., Aurora R. Cross-presentation by osteoclasts induces FoxP3 in CD8+ T cells. J Immunol 2009, 182:5477-5487.
15. Brianza S., D'Amelio P., Cerrato M., Bignardi C., Grimaldi A., Pescarmona G., et al. A dedicated image analysis software tool for the evaluation of the resorption activity of cultured osteoclasts. JIST 2008, 52. 030508-1030508-9.
16. Colucci S., Brunetti G., Rizzi R., Zonno A., Mori G., Colaianni G., et al. T cells support osteoclastogenesis in an in vitro model derived from human multiple myeloma bone disease: the role of the OPG/TRAIL interaction. Blood 2004, 104:3722-3730.
17. D'Amelio P., Grimaldi A., Di Bella S., Brianza S.Z., Cristofaro M.A., Tamone C., et al. Estrogen deficiency increases osteoclastogenesis up-regulating T cells activity: a key mechanism in osteoporosis. Bone 2008, 43:92-100.
18. Roato I., Brunetti G., Gorassini E., Grano M., Colucci S., Bonello L., et al. IL-7 up-regulates TNF-alpha-dependent osteoclastogenesis in patients affected by solid tumor. PLoS One 2006, 1:e124.
19. Purdue P.E., Koulouvaris P., Potter H.G., Nestor B.J., Sculco T.P. The cellular and molecular biology of periprosthetic osteolysis. Clin Orthop Relat Res 2007, 454:251-261.
20. Williams D.F. Titanium: epitome of biocompatibility or cause for concern. J Bone Joint Surg Br 1994, 76:348-349.
21. Landgraeber S., von Knoch M., Loer F., Brankamp J., Tsokos M., Grabellus F., et al. Association between apoptotis and CD4(+)/CD8(+) T-lymphocyte ratio in aseptic loosening after total hip replacement. Int J Biol Sci 2009, 5:182-191.
22. Gravallese E.M., Harada Y., Wang J.T., Gorn A.H., Thornhill T.S., Goldring S.R. Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis. Am J Pathol 1998, 152:943-951.
23. Taubman M.A., Valverde P., Han X., Kawai T. Immune response: the key to bone resorption in periodontal disease. J Periodontol 2005, 76:2033-2041.
24. Hercus B., Saeed S., Revell P.A. Expression profile of T cell associated molecules in the interfacial tissue of aseptically loosened prosthetic joints. J Mater Sci Mater Med 2002, 13:1153-1156.
25. Sutherland K.A., Rogers H.L., Tosh D., Rogers M.J. RANKL increases the level of Mcl-1 in osteoclasts and reduces bisphosphonate-induced osteoclast apoptosis in vitro. Arthritis Res Ther 2009, 11:R58.
26. Zhang Q., Badell I.R., Schwarz E.M., Boulukos K.E., Yao Z., Boyce B.F., et al. Tumor necrosis factor prevents alendronate-induced osteoclast apoptosis in vivo by stimulating Bcl-xL expression through Ets-2. Arthritis Rheum 2005, 52:2708-2718.