Selective determination of homocysteine at physiological pH using nanostructured film of aminothiadiazole modified electrode

Bioelectrochemistry

Volumn 79, Issue 2, 2010, Pages 168-172

  Kalimuthu, Palraj ^a   John, S Abraham ^a  

^a GANDHIGRAM RURAL UNIVERSITY   (India)

Author keywords

2 Amino 1,3,4 thiadiazole; AFM; Amperometry; Ascorbic acid; Electropolymerization; Homocysteine

Indexed keywords

AFM; AMPEROMETRY; ASCORBIC ACID; ASCORBIC ACIDS; HOMOCYSTEINES; THIADIAZOLES;

ATOMIC FORCE MICROSCOPY; ELECTROPOLYMERIZATION; GLASSY CARBON; KETONES; NANOSTRUCTURED MATERIALS; ORGANIC ACIDS; PH EFFECTS;

GLASS MEMBRANE ELECTRODES;

AMINOTHIADIAZOLE; ASCORBIC ACID; HOMOCYSTEINE; NANOMATERIAL;

AMPEROMETRY; ARTICLE; ATOMIC FORCE MICROSCOPY; ELECTRODE; HUMAN; OXIDATION; PH; POLYMERIZATION; SERUM; THICKNESS;

BLOOD CHEMICAL ANALYSIS; CARBON; ELECTROCHEMISTRY; ELECTRODES; GLASS; HOMOCYSTEINE; HUMANS; HYDROGEN-ION CONCENTRATION; LIMIT OF DETECTION; MICROSCOPY, ATOMIC FORCE; NANOSTRUCTURES; OXIDATION-REDUCTION; REPRODUCIBILITY OF RESULTS; THIADIAZOLES;

EID: 77955267396     PISSN: 15675394     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bioelechem.2010.02.006     Document Type: Article

References (21)

1. Medina M.A., Urdiales J.L., Amores-Sanchez M.I. Roles of homocysteine in cell metabolism. Eur. J. Biochem. 2001, 268:3871-3882.
2. Refsum H., Ueland P.M., Bygard O., Vollset S.E. Homo-cysteine and cardiovascular disease. Annu. Rev. Med. 1998, 49:31-62.
3. Nelen W.L.D.M., Blom H.J., Steegers E.A.P., Heijer M.D., Thomas C.M.G., Eskes T.K.A.B. Homocysteine and folate levels as risk factors for recurrent early pregnancy loss. Obstet. Gynecol. 2000, 95:519-524.
4. Biasioli S., Schiavon R. Homocysteine as a cardiovascular risk factor. Blood Purif. 2000, 18:177-182.
5. Falk E., Zhou J., Moller J. Homocysteine and atherothrombosis. Lipids 2001, 36:S3-S11.
6. Rees M.M., Rodgers G.M. Homocysteinemia: association of a metabolic disorder with vascular disease and thrombosis. Thromb. Res. 1993, 71:337-359.
7. Chou S.T., Ko L.E., Yang C.S. High performance liquid chromatography with fluorimetric detection for the determination of total homocysteine in human plasma: method and clinical applications. Anal. Chim. Acta 2001, 429:331-336.
8. Gong K., Zhu X., Zhao R., Xiong S., Mao L., Chen C. Rational attachment of synthetic triptycene orthoquinone onto carbon nanotubes for electrocatalysis and sensitive detection of thiols. Anal. Chem. 2005, 77:8158-8165.
9. Shinohar Y., Hasegawa H.T.K., Kashimoto T. Simultaneous determination of methionine and total homocysteine in human plasma by gas chromatography-mass spectrometry. J. Chromatogr. B 2001, 758:283-288.
10. Lawrence N.S., Davis J., Compton R.G. Electrochemical detection of thiols in biological media. Talanta 2001, 53:1089-1094.
11. Lawrence N.S., Davis J., Jiang L., Jones T.G.J., Davis N.S., Compton R.G. Selective determination of thiols: a novel electroanalytical approach. Analyst 2000, 125:661-663.
12. Nekrassova O., Kershaw J., Wadhawan J.D., Lawrence N.S., Compton R.G. The oxidation of cysteine by electrogenerated octacyanomolybdate (V). Phys. Chem. Chem. Phys. 2004, 6:1316-1320.
13. Chailapakul O., Siangproh W., Sarada B.V., Terashima C., Rao T.N., Tryk D.A., Fujishima A. The electrochemical oxidation of homocysteine at boron-doped diamond electrodes with application to HPLC amperometric detection. Analyst 2002, 127:1164-1168.
14. Chailapakul O., Aksharanandana P., Frelink T., Einaga Y., Fujishima A. The electrooxidation of sulfur-containing compounds at boron-doped diamond electrode. Sens. Actuators B 2001, 80:193-201.
15. Timur S., Odaci D., Dincer A., Zihnioglu F., Telefoncu A., Gorton L. Sulfhydryl oxidase modified composite electrode for the detection of reduced thiolic compounds. Sens. Actuators B 2007, 125:234-239.
16. Xu H., Zhang W., Zhu W., Wang D., Ye J., Yamamoto K., Jin L. Simultaneous determination of total homocysteine, cysteine and methionine in hypothyroid patients' plasma by liquid chromatography using platinum/poly(methyl violet) modified electrode. Anal. Chim. Acta 2005, 545:182-188.
17. Chen Z., Zu Y. Electrochemical recognition of single-methylene difference between cysteine and homocysteine. J. Electroanal. Chem. 2008, 624:9-13.
18. Agui L., Pena-Farfal C., Yanez-Sedeno P., Pingarron J.M. Electrochemical determination of homocysteine at a gold nanoparticle-modified electrode. Talanta 2007, 74:412-420.
19. Lawrence N.S., Deo R.P., Wang J. Detection of homocysteine at carbon nanotube paste electrodes. Talanta 2004, 63:443-449.
20. Kalimuthu P., John S.A. Modification of electrodes with nanostructured functionalized thiadiazole polymer film and its application to the determination of ascorbic acid. Electrochim. Acta 2009, 55:183-189.
21. Inoue T., Kirchhoff J.R. Electrochemical detection of thiols with a coenzyme pyrroloquinoline quinone modified electrode. Anal. Chem. 2000, 72:5755-5760.