A simple, noninvasive test for the diagnosis of liver fibrosis in patients with hepatitis C recurrence after liver transplantation

Journal of Viral Hepatitis

Volumn 17, Issue 9, 2010, Pages 640-649

  Cross, T J S ^a,d   Calvaruso, V ^b   Foxton, M R ^a   Manousou, P ^b   Quaglia, A ^a   Grillo, F ^b   Dhillon, A P ^b   Nolan, J ^a   Chang, T P ^b   O'Grady, J ^a   Heneghan, M A ^a   O'Beirne, J P ^b   Burroughs, A K ^b   Harrison, Phil M ^c  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b ROYAL FREE HOSPITAL   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d DERRIFORD HOSPITAL   (United Kingdom)

Author keywords

fibrosis; hepatitis C; liver transplantation; noninvasive marker

Indexed keywords

ASPARTATE AMINOTRANSFERASE;

ADULT; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; FEMALE; HEPATITIS C; HISTOLOGY; HUMAN; HUMAN TISSUE; INTERNATIONAL NORMALIZED RATIO; LIVER BIOPSY; LIVER FIBROSIS; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; RECURRENT DISEASE; SCORING SYSTEM;

ASPARTATE AMINOTRANSFERASES; BIOPSY; FEMALE; HEPATITIS C, CHRONIC; HISTOCYTOCHEMISTRY; HUMANS; LIVER; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; LONDON; MALE; MIDDLE AGED; PLATELET COUNT; RECURRENCE; RETROSPECTIVE STUDIES; ROC CURVE; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX;

EID: 77955256321     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2009.01222.x     Document Type: Article

References (37)

1. Armstrong GL, Alter MJ, McQuillan GM, Margolis HS. The past incidence of hepatitis C virus infection: implications for the future burden of chronic liver disease in the United States. Hepatology 2000 31 (3 777 782.
2. Hirashima N, Matsumoto Y, Ohono T, Kimura Y, Hasegawa I, Ueda R. Hepatic Fas protein expression might be a predictive factor for hepatocellular carcinoma development in patients with chronic hepatitis C undergoing interferon therapy. J Clin Gastroenterol 2002 34 (3 263 267.
3. Gretch DR, Bacchi CE, Corey L et al. Persistent hepatitis C virus infection after liver transplantation: clinical and virological features. Hepatology 1995 22 (1 1 9.
4. Gane EJ, Naoumov NV, Qian KP et al. A longitudinal analysis of hepatitis C virus replication following liver transplantation. Gastroenterology 1996 110 (1 167 177.
5. Chazouilleres O, Kim M, Combs C et al. Quantitation of hepatitis C virus RNA in liver transplant recipients. Gastroenterology 1994 106 (4 994 999. (Pubitemid 24109286)
6. Hopf U, Berg T, Konig V, Kuther S, Heuft HG, Lobeck H. Treatment of chronic hepatitis C with interferon alpha: long-term follow-up and prognostic relevance of HCV genotypes. J Hepatol 1996 24 (2 Suppl 67 73.
7. Zekry A, Whiting P, Crawford DH et al. Liver transplantation for HCV-associated liver cirrhosis: predictors of outcomes in a population with significant genotype 3 and 4 distribution. Liver Transpl 2003 9 (4 339 347.
8. Berenguer M, Ferrell L, Watson J et al. HCV-related fibrosis progression following liver transplantation: increase in recent years. J Hepatol 2000 32 (4 673 684.
9. Forman LM, Lewis JD, Berlin JA, Feldman HI, Lucey MR. The association between hepatitis C infection and survival after orthotopic liver transplantation. Gastroenterology 2002 122 (4 889 896.
10. Ortiz V, Berenguer M, Rayon JM, Carrasco D, Berenguer J. Contribution of obesity to hepatitis C-related fibrosis progression. Am J Gastroenterol 2002 97 (9 2408 2414.
11. Gane E. The natural history and outcome of liver transplantation in hepatitis C virus-infected recipients. Liver Transpl 2003 9 (11 S28 S34.
12. Brown Jr. R. Hepatitis C and liver transplantation. Nature 2005 436 : 973 978.
13. Firpi RJ, Abdelmalek MF, Soldevila-Pico Consuelo et al. One-year protocol liver biopsy can stratify fibrosis progression in liver transplant recipients with recurrent hepatitis C infection. Liver Transpl 2004 10 : 1240 1247.
14. Cadranel JF, Rufat P, Degos F. Practices of liver biopsy in France: results of a prospective nationwide survey. For the Group of Epidemiology of the French Association for the Study of the Liver (AFEF). Hepatology 2000 32 (3 477 481.
15. Bedossa P, Dargere D, Paradis V. Sampling variability of liver fibrosis in chronic hepatitis C. Hepatology 2003 38 (6 1449 1457. (Pubitemid 37466971)
16. Regev A, Berho M, Jeffers LJ et al. Sampling error and interobserver variation in liver biopsy in patients with chronic HCV infection. Am J Gastroenterol 2002 97 : 2614 2618.
17. Saadeh S, Cammell G, Carey WD, Younossi Z, Barnes D, Easley K. The role of liver biopsy in chronic hepatitis C. Hepatology 2001 33 (1 196 200.
18. Westin J, Lagging L, Dhillon A, Wejstal R, Norkrans G. Interobserver study of liver histopathology using the Ishak score in patients with chronic hepatitis C infection. Liver 1999 19 : 183 187.
19. Cross TJ, Rizzi P, Bruce M, Berry PA, Portmann B, Harrison PM. King's score: an accurate marker of cirrhosis in chronic hepatitis C. Eur J Gastroenterol Hepatol 2008 21 (7 730 738.
20. Cross TJ, Calvaruso V, Maimone S et al. Prospective Comparison of Fibroscan, King's Score and Liver Biopsy for the Assessment of Cirrhosis in Chronic Hepatitis C infection. J Viral Hepat 2009 In Press).
21. Foxton MR, Quaglia A, Muiesan P et al. The impact of diabetes mellitus on fibrosis progression in patients transplanted for hepatitis C. Am J Transplant 2006 6 (8 1922 1929.
22. Ishak K, Baptista A, Bianchi L et al. Histological grading and staging of chronic hepatitis. J Hepatol 1995 22 : 696 699.
23. Bedossa P, Poynard T. An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group. Hepatology 1996 24 (2 289 293.
24. Poynard T, Halfon P, Castera L et al. Standardization of ROC curve areas for diagnostic evaluation of liver fibrosis markers based on prevalences of fibrosis stages. Clin Chem 2007 53 (9 1615 1622.
25. Wai CT, Greenson JK, Fontana RJ et al. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology 2003 38 (2 518 526.
26. Neumann UP, Berg T, Bahra M et al. Fibrosis progression after liver transplantation in patients with recurrent hepatitis C. J Hepatol 2004 41 (5 830 836.
27. Berenguer M, Aguilera V, Prieto M et al. Effect of calcineurin inhibitors on survival and histologic disease severity in HCV-infected liver transplant recipients. Liver Transpl 2006 12 (5 762 767.
28. Kamimoto Y, Horiuchi S, Tanase S, Morino Y. Plasma clearance of intravenously injected aspartate aminotransferase isozymes: evidence for preferential uptake by sinusoidal liver cells. Hepatology 1985 5 : 367 375. (Pubitemid 15065940)
29. Okuda M, Li K, Beard MR et al. Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology 2002 122 (2 366 375.
30. Nalpas B, Vassault A, Le GuillouA et al. Serum activity of mitochondrial aspartate aminotransferase: a sensitive marker of alcoholism with or without alcoholic hepatitis. Hepatology 1984 4 : 893 896.
31. Bonacini M, Govindarajan S, Blatt LM, Schmid P, Conrad A, Lindsay KL. Patients co-infected with human immunodeficiency virus and hepatitis C virus demonstrate higher levels of hepatic HCV RNA. J Viral Hepat 1999 6 (3 203 208.
32. Poynard T, Bedossa P, Opolon P. Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups. Lancet 1997 9055 : 825 832.
33. Pohl A, Behling C, Oliver D, Kilani M, Monson P, Hassanein T. Serum aminotransferase levels and platelet counts as predictors of degree of fibrosis in chronic hepatitis C virus infection. Am J Gastroenterol 2001 96 (11 3142 3146.
34. Kawasaki T, Takeshita A, Souda K et al. Serum thrombopoietin levels in patients with chronic hepatitis and liver cirrhosis. Am J Gastroenterol 1999 94 (7 1918 1922.
35. Adinolfi LE, Giordano MG, Andreana A et al. Hepatic fibrosis plays a central role in the pathogenesis of thrombocytopenia in patients with chronic viral hepatitis. Br J Haematol 2001 113 (3 590 595.
36. Wali MH, Heydtmann M, Harrison RF, Gunson BK, Mutimer DJ. Outcome of liver transplantation for patients infected by hepatitis C, including those infected by genotype 4. Liver Transpl 2003 9 (8 796 804.
37. Carrion JA, Navasa M, Bosch J, Bruguera M, Gilabert R, Forns X. Transient elastography for diagnosis of advanced fibrosis and portal hypertension in patients with hepatitis C recurrence after liver transplantation. Liver Transpl 2006 12 : 1791 1798.