Patients co-infected with human immunodeficiency virus and hepatitis C virus demonstrate higher levels of hepatic HCV RNA

Journal of Viral Hepatitis

Volumn 6, Issue 3, 1999, Pages 203-208

  Bonacini, M ^a,d   Govindarajan, S ^a   Blatt, L M ^c   Schmid, P ^c   Conrad, A ^c   Lindsay, K L ^b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c National Genetics Institute   (United States)

^d RANCHO LOS AMIGOS NATIONAL REHABILITATION CENTER   (United States)

Author keywords

HCV; Hepatitis; HIV; Liver HCV RNA; RT PCR; Serum HCV RNA

Indexed keywords

VIRUS RNA;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; COMORBIDITY; CYTOPATHOGENIC EFFECT; DISEASE DURATION; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HISTOPATHOLOGY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIVER BIOPSY; LIVER LEVEL; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; VIRUS LOAD;

ADULT; AGED; HEPACIVIRUS; HEPATITIS C; HIV INFECTIONS; HIV-1; HUMANS; LIVER; MIDDLE AGED; RNA, VIRAL;

EID: 0033010901     PISSN: 13520504     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2893.1999.00153.x     Document Type: Article

References (27)

1. Yano M, Kumada M, Kage M et al. The long-tem pathological evolution of chronic hepatitis C. Hepatology 1996; 23: 1334-1340.
2. Simonetti RG, Camma' C, Fiorello F et al. Hepatitis C virus infection as a risk factor for hepatocellular carcinoma in patients with cirrhosis. A case-control study. Ann Intern Med 1992; 116: 97-102.
3. Pawlotsky JM. Measuring hepatitis C viremia: can we trust the assays? Hepatology 1997; 26: 1-4.
4. McGuinness PH, Bishop GA, Painter DM, Chan R, McCaughan GW. Hepatic hepatitis C RNA do not correlate with degree of liver injury in patients with chronic hepatitis C. Hepatology 1996; 23: 676-687.
5. Sakamoto N, Enomoto N, Kurosaki M, Marumo F, Sato C. Detection and quantification of hepatic C virus RNA replication in the liver. J Hepatol 1994; 20: 593-597.
6. Nakagawa H, Shimomura H, Hasui T, Tsuji H, Tsuji T. Quantitative detection of hepatitis C virus genome in liver tissue and circulation by competitive reverse transcription-polymerase chain reaction. Dig Dis Sci 1994; 39: 225-233.
7. Haydon GH, Jarvis LM, Blair CS et al. Clinical significance of intrahepatic hepatitis C virus levels in patients with chronic HCV infection. Gut 1998; 42: 570-575.
8. Gretch D, Corey L, Wilson J et al. Assessment of HCV RNA levels by quantitative competitive RNA PCR: high titer viremia correlates with advanced stage of disease. J Infect Dis 1994; 169: 1219-1225.
9. Sherman KE, O'Brien J, Gutierrez AG et al. Quantitative evaluation of HCV RNA in patients with concurrent human immunodeficiency virus infections. J Clin Microbiol 1993; 31: 2679-2682.
10. Eyster ME, Fried MW, DiBisceglie AM et al. Increasing hepatitis C virus RNA levels in hemophiliacs: relationship to HIV infection and liver disease. Blood 1994; 84: 1020-1023.
11. Tong MJ, Hwang SJ, Lefkowitz M ey al. Correlation of serum HCV RNA and alanine aminotransferase levels in chronic hepatitis C patients during treatment with ribavirin. J Gastroenterol Hepatol 1994; 9: 587-591.
12. Chomczinski P, Sacchi N. Single-step method of RNA isolation by acidic guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-159.
13. Knodell R, Ishak K, Black W et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic hepatitis. Hepatology 1981; 1: 431-435.
14. Poynard T, Bedossa P, Opolon P, for the OBSVIRC, METAVIR, CLINIVIR, and DOSIVIRC groups. Natural history of liver fibrosis progression in patients with chronic hepatitis C. Lancet 1997; 349: 825-832.
15. Marcellin P, Boyer N, Gervais A et al. Long-term histologic improvement and loss of detectable intrahepatic HCV RNA in patients with chronic hepatitis C and sustained response to interferon-alfa therapy. Ann Intern Med 1997; 127: 875-881.
16. Shindo M, Arai K, Sokawa Y, Okuno T. Hepatic HCV RNA as a predictor of a long-term response to alfa-interferon therapy. Ann Intern Med 1995; 122: 586-591.
17. Saleh MG, Tibbs CJ, Koskinas J et al. Hepatic and extrahepatic hepatitis C virus replication in relation to response to interferon therapy. Hepatology 1994; 20: 1399-1404.
18. Tong MJ, Blatt LM, McHutchison JG, Co R. Prediction of response during interferon α-2b therapy in chronic hepatitis C patients using viral and biochemical characteristics: a comparison. Hepatology 1997; 26: 1640-1645.
19. De Moliner L, Pontisso P, De Salvo GL, Cavalletto L, Chemello L, Alberti A. Serum and liver HCV RNA levels in patients with chronic hepatitis C: correlation with clinical and histological features. Gut 1998; 42: 856-860.
20. Waite J, Gilson RJC, Weller IVD et al. Hepatitis B virus reactivation or reinfection associated with HIV-1 infection. AIDS 1988; 2: 443-448.
21. Barbara G, DiLorenzo G, Soldini M et al. Hepatic glutathione deficiency in chronic hepatitis C; quantitative evaluation in patients who are HIV positive and HIV negative and correlations with plasmatic and lymphocytic concentrations and with the activity of the liver disease. Am J Gastroenterol 1996; 12: 2569-2573.
22. Garcia-Samaniego J, Soriano V, Castilla J et al. Influence of hepatitis C virus genotypes and HIV infection on histological severity of chronic hepatitis C. Am J Gastroenterol 1997; 92: 1130-1134.
23. DiMartino V, Saurini F, Samuel D et al. Long-term longitudinal study of intrahepatic hepatitis C virus replication after liver transplantation. Hepatology 1997; 26: 1343-1350.
24. Jarvis LM, Watson HG, McOmish F, Peutherer JF, Ludlam CA, Simmonds P. Frequent reinfection and reactivation of hepatitis C virus genotypes in multitransfused hemophiliacs. J Infect Dis 1994; 170: 1018-1022.
25. Lau JYN, Davis GL, Prescott LE et al. Distribution of hepatitis C virus genotypes determined by line probe assay in patients with chronic hepatitis C seen at tertiary referral centers in the United States. Ann Intern Med 1996; 124: 868-876.
26. Cathomas G, McGandy CE, Terracciano LM, Gudat F, Bianchi L. Detection and typing of hepatitis C RNA in liver biopsies and its relation to histopathology. Virchows Arch 1996; 429: 353-358.
27. Laskus T, Radkowski M, Wang LF, Vargas H, Rakela J. The presence of active hepatitis C virus replication in lymphoid tissue and various organs in patients coinfected with human immunodeficiency virus type 1. Hepatology 1998; 28: A276 (abstr).