Methylation-specific loop-mediated isothermal amplification for detecting hypermethylated DNA in simplex and multiplex formats

Clinical Chemistry

Volumn 56, Issue 8, 2010, Pages 1287-1296

  Zerilli, Francesco ^a   Bonanno, Cinzia ^b   Shehi, Erlet ^b   Amicarelli, Giulia ^b   Adlerstein, Daniel ^b   Makrigiorgos, G Mike ^c  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b Diasorin SpA   (Italy)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DEATH ASSOCIATED PROTEIN KINASE 1; GENOMIC DNA; PLASMID DNA; PROTEIN KINASE; PROTEIN P16; TRANSCRIPTION FACTOR GATA 5; UNCLASSIFIED DRUG;

ARTICLE; CANCER THERAPY; CARCINOGENESIS; CONTROLLED STUDY; DNA METHYLATION; FLUORESCENCE; GENE AMPLIFICATION; HUMAN; HUMAN TISSUE; LOOP MEDIATED ISOTHERMAL AMPLIFICATION; LUNG ADENOCARCINOMA; MELANOMA; METHYLATION SPECIFIC LOOP MEDIATED ISOTHERMAL AMPLIFICATION; POLYMERASE CHAIN REACTION; PROMOTER REGION; TUMOR SUPPRESSOR GENE; TURBIDIMETRY;

ADENOCARCINOMA; APOPTOSIS REGULATORY PROTEINS; BASE SEQUENCE; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES; CPG ISLANDS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA METHYLATION; DNA PRIMERS; FLUOROMETRY; GATA5 TRANSCRIPTION FACTOR; GENOME, HUMAN; HUMANS; INDICATORS AND REAGENTS; LUNG NEOPLASMS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; NEPHELOMETRY AND TURBIDIMETRY; NUCLEIC ACID AMPLIFICATION TECHNIQUES; PLASMIDS; PROMOTER REGIONS, GENETIC; SENSITIVITY AND SPECIFICITY; SULFITES;

EID: 77955234573     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2010.143545     Document Type: Article

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