Changes in oncomiR expression in CTCL cell lines during apoptosis induced by Notch inhibition

Leukemia Research

Volumn 34, Issue 9, 2010, Pages

  Manfè, Valentina ^a   Holst, Line Marie ^a   Rosbjerg, Anne ^a   Kamstrup, Maria R ^a   Kaczkowski, Bogumil ^b   Gniadecki, Robert ^a  

^a BISPEBJERG HOSPITAL   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA SECRETASE INHIBITOR; MICRORNA; MICRORNA 181A; MICRORNA 27A; NOTCH RECEPTOR; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

APOPTOSIS; CONTROLLED STUDY; CUTANEOUS T CELL LYMPHOMA; DOWN REGULATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LETTER; LYMPHOMA CELL; MYCOSIS FUNGOIDES; PRIORITY JOURNAL; SEZARY SYNDROME;

EID: 77955233086     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2010.03.035     Document Type: Letter

References (15)

1. Pui J.C., Allman D., Xu L., DeRocco S., Karnell F.G., Bakkour S., et al. Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity 1999, 11:299-308.
2. Weng A.P., Ferrando A.A., Lee W., Morris J.P., Silverman L.B., Sanchez-Irizarry C., et al. Activating mutations of Notch1 in human T cell acute lymphoblastic leukaemia. Science 2004, 306:269-271.
3. Kamstrup M.R., Ralfkiaer E., Skovgaard G.L., Gniadecki R. Potential involvement of Notch1 signalling in the pathogenesis of primary cutaneous CD30-positive lymphoproliferative disorders. Br J Dermatol 2008, 158:747-753.
4. Kamstrup MR, Gjerdrum LMR, Biskup E, Lauenborg BT, Ralfkiaer E, Woetmann A et al. Notch as a potential therapeutic target in cutaneous T-cell lynphoma. Submitted for publication.
5. Willemze R., Jaffe E.S., Burg G., Cerroni L., Berti E., Swerdlow S.H., et al. WHO-EORTC classification for cutaneous lymphomas. Blood 2005, 105:3768-3785.
6. Deangelo D.J., Stone R.M., Silverman L.B., Stock W., Attar E.C., Fearen I., et al. A phase I clinical trial of the Notch inhibitor MK-0752 in patients with T-cell acute lymphoblastic leukaemia/lymphoma (T-ALL) and other leukaemias. J Clin Oncol 2006 ASCO Annu Meet Proc Part I 2006, 24:6585.
7. Garzon R., Calin G.A., Croce C.M. MicroRNAs in cancer. Annu Rev Med 2009, 60:167-179.
8. Wang Y., Lee C.G.L. MicroRNA and cancer - focus on apoptosis. J Cell Mol 2008, 13:12-23.
9. Holst LM, Kaczkowski B, Gniadecki R. Reproducible pattern of microRNA in normal human skin. Exp Dermatol [in press].
10. Navarro A., Gaya A., Martinez A., Urbano-Ispizua A., Pons A., Balagué O., et al. MicroRNA expression profiling in classic Hodgkin lymphoma. Blood 2008, 111:2825-2832.
11. Yu J., Wang F., Yang G.H., Wang F.L., Ma Y.N., Du Z.W., et al. Human microRNA clusters: genomic organization and expression profile in leukaemia cell lines. Biochem Biophys Res Commun 2006, 349:59-68.
12. Ji J., Zhang J., Huang G., Qian J., Wang X., Mei S. Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation. FEBS Lett 2009, 583:759-766.
13. Zhang H, Li M, Han Y, Hong L, Gong T, Sun L et al. Down-Regulation of miR-27a might reverse multidrug resistance of esophageal squamous cell carcinoma. Dig Dis Sci 4.[in press].
14. Neilson J.R., Zheng G.X.Y., Burge C.B., Sharp P.A. Dynamic regulation of microRNAs expression in ordered stages of cellular development. Genes Dev 2007, 21:578-589.
15. Shi L., Cheng Z., Zhang J., Li R., Zhao P., Fu Z., et al. Hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells. Brain Res 2008, 1236:185-193.