Chromosome 9p21.3 polymorphism in a Chinese Han population is associated with angiographic coronary plaque progression in non-diabetic but not in type 2 diabetic patients

Cardiovascular Diabetology

Volumn 9, Issue , 2010, Pages

  Wang, Wei ^a   Peng, Wenhui ^a   Zhang, Xianling ^a   Lu, Lin ^a   Zhang, Ruiyan ^a   Zhang, Qi ^a   Wang, Lingjie ^a   Chen, Qiujing ^a   Shen, Weifeng ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; ORAL ANTIDIABETIC AGENT;

ADULT; ANGIOCARDIOGRAPHY; ARTICLE; CASE CONTROL STUDY; CHINESE; CHROMOSOME 9P; CHROMOSOME 9P21.3; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DISEASE COURSE; FEMALE; FOLLOW UP; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOSITY; HUMAN; INSULIN TREATMENT; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; QUANTITATIVE ANALYSIS; RISK FACTOR; AGED; ASIAN; CHINA; CHROMOSOME 9; ETHNOLOGY; GENETICS; MIDDLE AGED; RADIOGRAPHY; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICS;

AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; CHROMOSOMES, HUMAN, PAIR 9; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; DIABETES MELLITUS, TYPE 2; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 77955222624     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-9-33     Document Type: Article

References (30)

1. Consortium WTCC. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007, 447(7145):661-678. 10.1038/nature05911, 2719288, 17554300.
2. Newton-Cheh C, Cook NR, VanDenburgh M, Rimm EB, Ridker PM, Albert CM. A common variant at 9p21 is associated with sudden and arrhythmic cardiac death. Circulation 2009, 120(21):2062-2068. 10.1161/CIRCULATIONAHA.109.879049, 19901189.
3. Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B, Dixon RJ, Meitinger T, Braund P, Wichmann HE, Barrett JH, Konig IR, Stevens SE, Szymczak S, Tregouet DA, Iles MM, Pahlke F, Pollard H, Lieb W, Cambien F, Fischer M, Ouwehand W, Blankenberg S, Balmforth AJ, Baessler A, Ball SG, Strom TM, Braenne I, Gieger C, Deloukas P, Tobin MD, Ziegler A, Thompson JR, Schunkert H. Genomewide association analysis of coronary artery disease. N Engl J Med 2007, 357(5):443-453. 10.1056/NEJMoa072366, 2719290, 17634449.
4. Wang Q. Molecular genetics of coronary artery disease. Curr Opin Cardiol 2005, 20(3):182-188. 10.1097/01.hco.0000160373.77190.f1, 1579824, 15861005.
5. McPherson R. Chromosome 9p21 and coronary artery disease. N Engl J Med 2010, 362(18):1736-1737. 10.1056/NEJMcibr1002359, 20445187.
6. Palomaki GE, Melillo S, Bradley LA. Association between 9p21 genomic markers and heart disease: a meta-analysis. JAMA 2010, 303(7):648-656. 10.1001/jama.2010.118, 20159873.
7. Shunkert H, Gotz A, Braund P, McGinnis R, Tregouet DA, Mangino M, Linsel-Nitschke P, Cambien F, Hengstenberg C, Stark K, Blankenberg S, Tiret L, Ducimetiere P, Keniry A, Ghori MJ, Schreiber S, El Mokhtari NE, Hall AS, Dixon RJ, Goodall AH, Liptau H, Pollard H, Schwarz DF, Hothorn LA, Wichmann HE, Konig IR, Fischer M, Meisinger C, Ouwehand W, Deloukas P, Thompson JR, Erdmann J, Ziegler A, Samani NJ. Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation 2008, 117(13):1675-1684. 10.1161/CIRCULATIONAHA.107.730614, 2689930, 18362232.
8. Doria A, Wojcik J, Xu R, Gervino EV, Hauser TH, Johnstone MT, Nolan D, Hu FB, Warram JH. Interaction between poor glycemic control and 9p21 locus on risk of coronary artery disease in type 2 diabetes. JAMA 2008, 300(20):2389-2397. 10.1001/jama.2008.649, 2762126, 19033589.
9. Schunkert H, Gotz A, Braund P, McGinnis R, Tregouet DA, Mangino M, Linsel-Nitschke P, Cambien F, Hengstenberg C, Stark K, Blankenberg S, Tiret L, Ducimetiere P, Keniry A, Ghori MJ, Schreiber S, El Mokhtari NE, Hall AS, Dixon RJ, Goodall AH, Liptau H, Pollard H, Schwarz DF, Hothorn LA, Wichmann HE, Konig IR, Fischer M, Meisinger C, Ouwehand W, Deloukas P, Thompson JR, Erdmann J, Ziegler A, Samani NJ. Coronary artery disease-associated locus on chromosome 9p21 and early markers of atherosclerosis. Arterioscler Thromb Vasc Biol 2008, 28(9):1679-1683. 10.1161/ATVBAHA.108.170332, 18599798.
10. Silander K, Tang H, Myles S, Jakkula E, Timpson NJ, Cavalli-Sforza L, Peltonen L. Worldwide patterns of haplotype diversity at 9p21.3, a locus associated with type 2 diabetes and coronary heart disease. Genome Med 2009, 1(5):51. 10.1186/gm51, 2689443, 19463184.
11. Gori F, Specchia C, Pietri S, Crociati L, Barlera S, Franciosi M, Nicolucci A, Signorini S, Brambilla P, Franzosi MG. Common genetic variants on chromosome 9p21 are associated with myocardial infarction and type 2 diabetes in an Italian population. BMC Med Genet 2010, 11:60. 10.1186/1471-2156-11-60, 2871267, 20403154.
12. Aronson D, Rayfield EJ. How hyperglycemia promotes atherosclerosis: molecular mechanisms. Cardiovasc Diabetol 2002, 1:1. 10.1186/1475-2840-1-1, 116615, 12119059.
13. Pu LJ, Lu L, Xu XW, Zhang RY, Zhang Q, Zhang JS, Hu J, Yang ZK, Ding FH, Chen QJ, Lou S, Shen J, Fang DH, Shen WF. Value of serum glycated albumin and high-sensitivity C-reactive protein levels in the prediction of presence of coronary artery disease in patients with type 2 diabetes. Cardiovasc Diabetol 2006, 5:27. 10.1186/1475-2840-5-27, 1764721, 17178005.
14. Andersson C, Gislason GH, Weeke P, Hoffmann S, Hansen PR, Torp-Pedersen C, Sogaard P. Diabetes is associated with impaired myocardial performance in patients without significant coronary artery disease. Cardiovasc Diabetol 2010, 9:3. 10.1186/1475-2840-9-3, 2818623, 20082690.
15. Chen SN, Ballantyne CM, Gotto AM, Marian AJ. The 9p21 susceptibility locus for coronary artery disease and the severity of coronary atherosclerosis. BMC Cardiovasc Disord 2009, 9:3. 10.1186/1471-2261-9-3, 2637231, 19173706.
16. Peng WH, Lu L, Hu J, Yan XX, Zhang Q, Zhang RY, Chen QJ, Shen WF. Decreased serum esRAGE level is associated with angiographically determined coronary plaque progression in diabetic patients. Clin Biochem 2009, 42(12):1252-1259. 10.1016/j.clinbiochem.2009.04.017, 19439163.
17. Zheng JL, Lu L, Hu J, Zhang RY, Zhang Q, Chen QJ, Shen WF. Increased serum YKL-40 and C-reactive protein levels are associated with angiographic lesion progression in patients with coronary artery disease. Atherosclerosis 2009, 210(2):590-595. 10.1016/j.atherosclerosis.2009.12.016, 20056225.
18. Lansky AJ, Desai K, Leon MB. Quantitative coronary angiography in regression trials: a review of methodologic considerations, endpoint selection, and limitations. Am J Cardiol 2002, 89(4A):4B-9B. 10.1016/S0002-9149(01)02326-8, 11879660.
19. Berry C, L'Allier PL, Gregoire J, Lesperance J, Levesque S, Ibrahim R, Tardif JC. Comparison of intravascular ultrasound and quantitative coronary angiography for the assessment of coronary artery disease progression. Circulation 2007, 115(14):1851-1857. 10.1161/CIRCULATIONAHA.106.655654, 17389269.
20. Peng WH, Lu L, Zhang Q, Zhang RY, Wang LJ, Yan XX, Chen QJ, Shen WF. Chromosome 9p21 polymorphism is associated with myocardial infarction but not with clinical outcome in Han Chinese. Clin Chem Lab Med 2009, 47(8):917-922. 10.1515/CCLM.2009.215, 19548844.
21. Ye S, Willeit J, Kronenberg F, Xu Q, Kiechl S. Association of genetic variation on chromosome 9p21 with susceptibility and progression of atherosclerosis: a population-based, prospective study. Journal of the American College of Cardiology 2008, 52(5):378-384. 10.1016/j.jacc.2007.11.087, 18652946.
22. Hoppmann P, Erl A, Turk S, Tiroch K, Mehilli J, Schomig A, Kastrati A, Koch W. No association of chromosome 9p21.3 variation with clinical and angiographic outcomes after placement of drug-eluting stents. JACC Cardiovasc Interv 2009, 2(11):1149-1155. 10.1016/j.jcin.2009.08.021, 19926059.
23. Buysschaert I, Carruthers KF, Dunbar DR, Peuteman G, Rietzschel E, Belmans A, Hedley A, De Meyer T, Budaj A, Van de Werf F, Lambrechts D, Fox KA. A variant at chromosome 9p21 is associated with recurrent myocardial infarction and cardiac death after acute coronary syndrome: The GRACE Genetics Study. Eur Heart J 2010, 31(9):1132-1141. 10.1093/eurheartj/ehq053, 20231156.
24. Liu KY, Muehlschlegel JD, Perry TE, Fox AA, Collard CD, Body SC, Shernan SK. Common genetic variants on chromosome 9p21 predict perioperative myocardial injury after coronary artery bypass graft surgery. J Thorac Cardiovasc Surg 2010, 139(2):483-488. 488 e481-482, 10.1016/j.jtcvs.2009.06.032, 19819472.
25. Broadbent HM, Peden JF, Lorkowski S, Goel A, Ongen H, Green F, Clarke R, Collins R, Franzosi MG, Tognoni G, Seedorf U, Rust S, Eriksson P, Hamsten A, Farrall M, Watkins H. Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p. Human molecular genetics 2008, 17(6):806-814. 10.1093/hmg/ddm352, 18048406.
26. Holdt LM, Beutner F, Scholz M, Gielen S, Gabel G, Bergert H, Schuler G, Thiery J, Teupser D. ANRIL Expression Is Associated With Atherosclerosis Risk at Chromosome 9p21. Arterioscler Thromb Vasc Biol 2010, 30(3):620-627. 10.1161/ATVBAHA.109.196832, 20056914.
27. Jarinova O, Stewart AF, Roberts R, Wells G, Lau P, Naing T, Buerki C, McLean BW, Cook RC, Parker JS, McPherson R. Functional Analysis of the Chromosome 9p21.3 Coronary Artery Disease Risk Locus. Arterioscler Thromb Vasc Biol 2009, 29(10):1671-1677. 10.1161/ATVBAHA.109.189522, 19592466.
28. Cunnington MS, Santibanez Koref M, Mayosi BM, Burn J, Keavney B. Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression. PLoS Genet 2010, 6(4):e1000899. 10.1371/journal.pgen.1000899, 2851566, 20386740.
29. Visel A, Zhu Y, May D, Afzal V, Gong E, Attanasio C, Blow MJ, Cohen JC, Rubin EM, Pennacchio LA. Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice. Nature 2010, 464(7287):409-412. 10.1038/nature08801, 20173736.
30. Manolio TA, Bailey-Wilson JE, Collins FS. Genes, environment and the value of prospective cohort studies. Nat Rev Genet 2006, 7(10):812-820. 10.1038/nrg1919, 16983377.