Semen Hoveniae extract protects against acute alcohol-induced liver injury in mice

Pharmaceutical Biology

Volumn 48, Issue 8, 2010, Pages 953-958

  Du, Jian ^a   He, Da ^a   Sun, Lian Na ^a   Han, Ting ^a   Zhang, Hong ^a   Qin, Lu Ping ^a   Rahman, Khalid ^b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

Author keywords

Gastric metabolism; Liver damage; Semen Hoveniae

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ALCOHOL DEHYDROGENASE; ASPARTATE AMINOTRANSFERASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HOVENIAE DULCIS EXTRACT; PLANT EXTRACT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL BLOOD LEVEL; ALCOHOL LIVER DISEASE; ALCOHOL METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; HOVENIAE DULCIS; IN VIVO STUDY; LIPID PEROXIDATION; LIVER INJURY; LIVER PARENCHYMA; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; PLANT SEED; RHAMNACEAE; SINGLE DRUG DOSE; SPECTROPHOTOMETRY; TOXICITY TESTING;

ACUTE DISEASE; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; LIVER DISEASES, ALCOHOLIC; MALE; MICE; PLANT EXTRACTS; RANDOM ALLOCATION; RHAMNACEAE; SEEDS;

HOVENIA DULCIS; MUS; RHAMNACEAE;

EID: 77955190416     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880200903300196     Document Type: Article

References (33)

1. Aasmoe L, Winberg J, Aarbakke J (1998): The role of liver alcohol dehydrogenase isoenzymes in the oxidation of glycolethers in male and female rats. Toxicol Appl Pharmacol 150: 86-90.
2. Aoa ZH, Xua ZH, Lub ZM, Xua HY, Zhanga XM, Doua WF (2009): Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases. J Ethnopharmacol 121: 194-212.
3. Arteel G, Marsano I, Mendea C, Bentley F, McLain CJ (2003): Advances in alcoholic liver diseases. Best Pract Res Clin Gastoenterol 17: 625-647.
4. Arteel GE, Uesugi T, Bevan LN, Gabele E, Wheeler MD, McKim SE, Thurman RG (2002): Protective effects of antioxidant raxofe- last in alcohol-induced liver disease in mice. Biol Chem 383: 663-670.
5. Bergmeyer HU (1998): Methods of Enzymatic Analysis. New York, Academic Press, pp. 261-265.
6. Beuge JA, Aust SD (1978): Microsomal lipid peroxidation. Methods Enzymol 52: 302-311.
7. Bors W, Michel C (1999): Antioxidant capacity of flavanols and gal- late esters: Pulse radiolysis studies. Free Radic Biol Med 27: 1413-1426.
8. Cederbaum AI (2001): Alcohol oxidative stress and cell injury. Free Radic Biol Med 31: 1524-1526.
9. Dey A, Cederbaum AI (2006): Alcohol and oxidative liver injury. Hepatology 43: S63-S74.
10. Diluzio NR (1964): Prevention of the acute ethanol-induced fatty liver by the simultaneous administration of antioxidants. Life Sci 3: 113-118.
11. Diluzio NR, Hartman AD (1967): Role of lipid peroxidation in the pathogenesis of the ethanol-induced fatty liver. Fed Proc 26: 1436-1442.
12. Ellman GL (1959): Tissue sulfhydryl groups. Arch Biochem Biophys 82: 70-77.
13. Goldberg DM, Watts C (1965): Serum enzyme changes as evidence of liver reaction to oral alcohol. Gastroenterology 49: 256-261.
14. Gross A, Ong TR, Grant R, Hoffmann T, Gregory DD, Sreerama L (2009): Human aldehyde dehydrogenase-catalyzed oxidation of ethylene glycol ether aldehydes. Chem Biol Interact 178: 56-63.
15. Habig WH, Pabst MJ, Jakoby WB (1974): Glutathione S-transferases the first step in mercapturic acid formation. J Biol Chem 249: 7130-7139.
16. Hase K, Ohsugi M, Xiong Q, Basnet P, Kadata S, Namba T (1997): Hepatoprotective effect of Hovenia dulcis Thunb on experimental liver injuries induced by carbon tetrachloride or D-galactos- amine/lipopolysaccharide. Biol Pharm Bull 20: 381-385.
17. Haslam E (1998): Practical Polyphenolics: From Structure to Molecular Recognition and Physiological Action. Cambridge, Cambridge University Press, pp. 356-365.
18. Iimuro Y, Bradford BU, Forman DT, Thurman RG (1996): Glycine prevents alcohol-induced liver injury by decreasing alcohol in the rat stomach. Gastroenterology 110: 1536-1542.
19. Lang CH, Pruznak AM, Nystrom GJ, Vary TC (2009): Alcohol-induced decrease in muscle protein synthesis associated with increased binding of mTOR and raptor: Comparable effects in young and mature rats. Nutr Metab (Lond) 6: 4.
20. Li G, Min BS, Zheng C, Lee J, Oh SR, Ahn KS, Lee HK (2005): Neuroprotective and free radical scavenging activities ofphenolic compounds from Hovenia dulcis. Arch Pharm Res 28: 804-809.
21. Lieber CS (1997): Ethanol metabolism cirrhosis and alcoholism. Clin Chim Acta 257: 59-84.
22. Livy DJ, Parnell SE, West JR (2003): Blood ethanol concentration profiles: A comparison between rats and mice. Alcohol 29: 165-171.
23. Martin JP, Dailey M, Sugarman E (1987): Negative and positive assays of superoxide dismutase based on hematoxylin autoxidation. Arch Biochem Biophys 255: 329-336.
24. Matsuda H, Hiroshi S, Ninomiya K, Yoshikawa M (2002): Inhibitory mechanism of costunolide, a sesquiterpene lactone isolated from Laurus Nobilis, on blood-ethanol elevation in rats: Involvement of inhibition of gastric emptying and increase in gastric juice secretion. Alcohol 37: 121-127.
25. Meagher EA, Barry OP, Burke A, Lucey MR, Lawson JA, Rokach J (1999): Alcohol-induced generation of lipid peroxidation products in humans. J Clin Invest 104: 805-813.
26. Niemela O, Parkkila S, Yla-Herttuala S, Villanueva J, Ruebner B, Halsted CH (1995): Sequential acetaldehyde production lipid peroxidation and fibrogenesis in micropig model of alcohol- induced liver disease. Hepatology 22: 1208-1212.
27. Rej R (1978): Aspartate aminotransferase activity and isoenzymes proportions in human liver tissue. Clin Chem 24: 1971-1979.
28. Shaw S, Jayatilleke E (1990): The role of aldehyde oxidase in ethanol induced hepatic lipid peroxidation in the rat. Biochemistry 268: 579-583.
29. Teli MR, Day CP, Burt AD, Bennett MK, James OFW (1995): Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver. Lancet 346: 987-990.
30. Tinoco MT, Ramos P, Candeias MF (2009): Effects of a hexane extract from Laurus novocanariensis leaves on the ethanol metabolism of Wistar rats. Fitoterapia 80: 130-133.
31. Wanless IR, Shiota K (2004): The pathogenesis of nonalcoholic steato- hepatitis and other fatty liver diseases: a four-step model including the role of lipid release and hepatic venular obstruction in the progression to cirrhosis. Semin Liver Dis 24: 99-106.
32. Wu D, Cederbaum AI (2003): Alcohol oxidative stress and free radical damage. Alcohol Res Health 27: 277-284.
33. Yoshikawa M, Ueda T, Muraoka O, Aoyama H, Matsuda H, Shimoda H, Yamahara J, Murakami N (1995): Absolute stereostructures of hovenidulciosides A1 and A2 bioactive novel triterpene glyco- sides from hoveniae semen seu fructus, the seeds and fruit of Hovenia dulcis Thunb. Chem Pharm Bull 43: 532-534.