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Volumn 8, Issue 8, 2010, Pages 1079-1090

Pitavastatin for the treatment of primary hyperlipidemia and mixed dyslipidemia

Author keywords

cholesterol; coronary heart disease; dyslipidemia; HMG CoA reductase inhibitors; LDL; pitavastatin

Indexed keywords

ATAZANAVIR; ATORVASTATIN; CERIVASTATIN; COMPACTIN; CYCLOSPORIN; DIGOXIN; ENALAPRIL; ERYTHROMYCIN; EZETIMIBE; FENOFIBRATE; FLUINDOSTATIN; GEMFIBROZIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ITRACONAZOLE; KETOCONAZOLE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEVINOLIN; NICARDIPINE; PITAVASTATIN; PRAVASTATIN; PROTEINASE INHIBITOR; RIFAMPICIN; ROSUVASTATIN; SIMVASTATIN; TRIACYLGLYCEROL; VERAPAMIL; WARFARIN; CYTOCHROME P450; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN RECEPTOR; QUINOLINE DERIVATIVE;

EID: 77955188767     PISSN: 14779072     EISSN: 17448344     Source Type: Journal    
DOI: 10.1586/erc.10.82     Document Type: Review
Times cited : (16)

References (69)
  • 1
    • 3142729178 scopus 로고    scopus 로고
    • Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines
    • Grundy SM, Cleeman JI, Merz CNB et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Circulation 110, 227-239 (2004).
    • (2004) Circulation , vol.110 , pp. 227-239
    • Grundy, S.M.1    Cleeman, J.I.2    Merz, C.N.B.3
  • 2
    • 27644544308 scopus 로고    scopus 로고
    • Pleiotropic effects of statins: Benefit beyond cholesterol reduction? A meta-regression analysis
    • Robinson JG, Smith B, Maheshwari N, Schrott H. Pleiotropic effects of statins: benefit beyond cholesterol reduction? A meta-regression analysis. J. Am. Coll. Cardiol. 46, 1855-1862 (2005).
    • (2005) J. Am. Coll. Cardiol. , vol.46 , pp. 1855-1862
    • Robinson, J.G.1    Smith, B.2    Maheshwari, N.3    Schrott, H.4
  • 3
    • 0035897696 scopus 로고    scopus 로고
    • Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA, 285,2486-2497(2001)
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 4
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
    • Cholesterol Treatment Trialists' Collaborators
    • Cholesterol Treatment Trialists' Collaborators. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet 366, 1267-1278 (2005).
    • (2005) Lancet , vol.366 , pp. 1267-1278
  • 7
    • 0034840928 scopus 로고    scopus 로고
    • Synthesis and biological evaluations of quinoline-based HMG-CoA reductase inhibitors
    • Suzuki M, Iwasaki H, Fujikawa Y et al. Synthesis and biological evaluations of quinoline-based HMG-CoA reductase inhibitors. Bioorg. Med. Chem. 9, 2727-2743 (2001).
    • (2001) Bioorg. Med. Chem. , vol.9 , pp. 2727-2743
    • Suzuki, M.1    Iwasaki, H.2    Fujikawa, Y.3
  • 8
    • 0034570787 scopus 로고    scopus 로고
    • Relative induction of mRNA for HMG CoA reductase and LDL receptor by five different HMG-CoA reductase inhibitors in cultured human cells
    • Morikawa S, Umetani M, Nakagawa S et al. Relative induction of mRNA for HMG CoA reductase and LDL receptor by five different HMG-CoA reductase inhibitors in cultured human cells. J. Atheroscler. Thromb. 7(3), 138-144 (2000).
    • (2000) J. Atheroscler. Thromb. , vol.7 , Issue.3 , pp. 138-144
    • Morikawa, S.1    Umetani, M.2    Nakagawa, S.3
  • 9
    • 0141988934 scopus 로고    scopus 로고
    • Pitavastatin: Efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor
    • Kajinami K, Takekoshi N, Saito Y. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor. Cardiovasc. Drug Rev. 21(3), 199-215 (2003).
    • (2003) Cardiovasc. Drug Rev. , vol.21 , Issue.3 , pp. 199-215
    • Kajinami, K.1    Takekoshi, N.2    Saito, Y.3
  • 10
    • 33745243715 scopus 로고    scopus 로고
    • Drug-drug interaction between pitavastatin and various drugs via OATP1B1
    • Hirano M, Maeda K, Shitara, Sugiyama Y. Drug-drug interaction between pitavastatin and various drugs via OATP1B1. DrugMetab. Dispos. 34(7), 1229-1236 (2006).
    • (2006) DrugMetab. Dispos. , vol.34 , Issue.7 , pp. 1229-1236
    • Hirano, M.1    Maeda, K.2    Shitara Sugiyama, Y.3
  • 11
    • 4644364576 scopus 로고    scopus 로고
    • Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans
    • Hirano M, Maeda K, Shitara Y, Sugiyama Y. Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans. J. Pharmacol. Exp. Ther. 311(1), 139-146 (2004).
    • (2004) J. Pharmacol. Exp. Ther. , vol.311 , Issue.1 , pp. 139-146
    • Hirano, M.1    Maeda, K.2    Shitara, Y.3    Sugiyama, Y.4
  • 12
    • 70349739250 scopus 로고    scopus 로고
    • The SLCO1B15 genetic variant is associated with statin-induced side effects
    • Voora D, Shah SH, Spasojevic I et al. The SLCO1B15 genetic variant is associated with statin-induced side effects. J. Am. Coll. Cardiol. 54(17), 1609-1616 (2009).
    • (2009) J. Am. Coll. Cardiol. , vol.54 , Issue.17 , pp. 1609-1616
    • Voora, D.1    Shah, S.H.2    Spasojevic, I.3
  • 13
    • 49949104757 scopus 로고    scopus 로고
    • SLCO1B1 variants and statin-induced myopathy - a genome-wide study
    • SEARCH Collaborative Group
    • SEARCH Collaborative Group. SLCO1B1 variants and statin-induced myopathy - a genome-wide study. N. Engl. J. Med. 359(8),789-799(2008).
    • (2008) N. Engl. J. Med. , vol.359 , Issue.8 , pp. 789-799
  • 15
    • 35448946484 scopus 로고    scopus 로고
    • SLCO1B1 (OATP1B1, an uptake transporter) and ABCG2 (BCRP, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers
    • Ieiri I, Suwannakul S, Maeda K et al. SLCO1B1 (OATP1B1, an uptake transporter) and ABCG2 (BCRP, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers. Clin. Pharmacol. Ther. 82(5), 541-547 (2007).
    • (2007) Clin. Pharmacol. Ther. , vol.82 , Issue.5 , pp. 541-547
    • Ieiri, I.1    Suwannakul, S.2    Maeda, K.3
  • 16
  • 17
    • 33845420011 scopus 로고    scopus 로고
    • Drug interactions with lipid-lowering drugs: Mechanisms and clinical relevance
    • Neuvonen PJ, Niemi M, Backman JT. Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance.Clin. Pharmacol. Ther. 80(6),565-581(2006).
    • (2006) Clin. Pharmacol. Ther. , vol.80 , Issue.6 , pp. 565-581
    • Neuvonen, P.J.1    Niemi, M.2    Backman, J.T.3
  • 18
    • 33748042671 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3- methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: Drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions
    • Shitara Y, Sugiyama Y. Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions. Pharmacol. Ther. 112(1), 71-105 (2006).
    • (2006) Pharmacol. Ther. , vol.112 , Issue.1 , pp. 71-105
    • Shitara, Y.1    Sugiyama, Y.2
  • 20
    • 27444434929 scopus 로고    scopus 로고
    • Effects of grapefruit juice on the pharmacokinetics of pitavastatin and atorvastatin
    • Ando H, Tsuroka S, Yanagihara H et al. Effects of grapefruit juice on the pharmacokinetics of pitavastatin and atorvastatin. Br. J. Clin. Pharmacol. 60(5), 494-497 (2005).
    • (2005) Br. J. Clin. Pharmacol. , vol.60 , Issue.5 , pp. 494-497
    • Ando, H.1    Tsuroka, S.2    Yanagihara, H.3
  • 21
    • 77749329736 scopus 로고    scopus 로고
    • Pitavastatin: A new HMG-CoA reductase inhibitor
    • Wensel TM, Waldrop BA, Wensel B. Pitavastatin: a new HMG-CoA reductase inhibitor. Ann. Pharmacother. 144, 507-514 (2010).
    • (2010) Ann. Pharmacother. , vol.144 , pp. 507-514
    • Wensel, T.M.1    Waldrop, B.A.2    Wensel, B.3
  • 22
    • 33644913688 scopus 로고    scopus 로고
    • Effects of acid and lactone forms of eight HMG-CoA reductase inhibitors on CYP-mediated metabolism and MDR1- mediated transport
    • Sakaeda T, Fujino H, Komoto C et al. Effects of acid and lactone forms of eight HMG-CoA reductase inhibitors on CYP-mediated metabolism and MDR1- mediated transport. Pharm. Res. 23(3), 502-512 (2005).
    • (2005) Pharm. Res. , vol.23 , Issue.3 , pp. 502-512
    • Sakaeda, T.1    Fujino, H.2    Komoto, C.3
  • 23
    • 0036233667 scopus 로고    scopus 로고
    • Glucuronidation of statins in animals and humans: A novel mechanism of statin lactonization
    • Prueksaritanont T, Subramanian R, Fang X et al. Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization. DrugMetab. Disp. 30(5), 505-512 (2002).
    • (2002) DrugMetab. Disp. , vol.30 , Issue.5 , pp. 505-512
    • Prueksaritanont, T.1    Subramanian, R.2    Fang, X.3
  • 24
    • 0036266987 scopus 로고    scopus 로고
    • Mechanistic studies on metabolic interactions between gemfibrozil and statins
    • Prueksaritanont T, Zhao J, Ma B et al. Mechanistic studies on metabolic interactions between gemfibrozil and statins. J. Pharm. Exp. Ther. 301(3), 1042-1051 (2002).
    • (2002) J. Pharm. Exp. Ther. , vol.301 , Issue.3 , pp. 1042-1051
    • Prueksaritanont, T.1    Zhao, J.2    Ma, B.3
  • 25
    • 0036843479 scopus 로고    scopus 로고
    • Effects of fibrates on metabolism of statins in human hepatocytes
    • Prueksaritanont T, Tang C, Qui Y et al. Effects of fibrates on metabolism of statins in human hepatocytes. Drug Metab. Dispos. 30(11), 1280-1287 (2002).
    • (2002) Drug Metab. Dispos. , vol.30 , Issue.11 , pp. 1280-1287
    • Prueksaritanont, T.1    Tang, C.2    Qui, Y.3
  • 26
    • 3242695305 scopus 로고    scopus 로고
    • Effect of gemfibrozil on the metabolism of pitavastatin - Determining the best animal model for human CYP and UGT activities
    • Fujino H, Saito T, Tsunenari Y, Kojima J. Effect of gemfibrozil on the metabolism of pitavastatin - determining the best animal model for human CYP and UGT activities. DrugMetabol. Drug Interact. 20(1-2), 25-42 (2004).
    • (2004) DrugMetabol. Drug Interact. , vol.20 , Issue.1-2 , pp. 25-42
    • Fujino, H.1    Saito, T.2    Tsunenari, Y.3    Kojima, J.4
  • 27
    • 33750731687 scopus 로고    scopus 로고
    • Role of p-glycoprotein in statin drug interactions
    • Holtzman CW, Wiggins BS, Spinler SA. Role of p-glycoprotein in statin drug interactions. Pharmacotherapy 26(11), 1601-1607 (2006).
    • (2006) Pharmacotherapy , vol.26 , Issue.11 , pp. 1601-1607
    • Holtzman, C.W.1    Wiggins, B.S.2    Spinler, S.A.3
  • 28
    • 0034866642 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors (statins) characterized as direct inhibitors of P-glycoprotein
    • Wang E, Casciano CN, Clement RP, Johnson WW. HMG-CoA reductase inhibitors (statins) characterized as direct inhibitors of P-glycoprotein. Pharm. Res. 18(6), 800-806 (2001).
    • (2001) Pharm. Res. , vol.18 , Issue.6 , pp. 800-806
    • Wang, E.1    Casciano, C.N.2    Clement, R.P.3    Johnson, W.W.4
  • 29
    • 84990240607 scopus 로고    scopus 로고
    • Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase - Effect of cMOAT deficiency on hepatobiliary excretion in rats and of mdr1a/b gene disruption on tissue distribution in mice
    • Fujino H, Yamada I, Shimada S, Kojima J. Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase - effect of cMOAT deficiency on hepatobiliary excretion in rats and of mdr1a/b gene disruption on tissue distribution in mice. Drug Metab. Pharmacokinet. 17(5), 449-456 (2002).
    • (2002) Drug Metab. Pharmacokinet. , vol.17 , Issue.5 , pp. 449-456
    • Fujino, H.1    Yamada, I.2    Shimada, S.3    Kojima, J.4
  • 30
    • 84925566035 scopus 로고    scopus 로고
    • Drug-drug interaction study to assess the effects of multiple dose of pitavastatin (Livalo®) on steady-state warfarin in healthy adult volunteers. XV International Symposium on Atherosclerosis 2009
    • 14-18 June 2009, Boston, MA, USA
    • Inagaki Y, Hunt T, Arana B et al. Drug-drug interaction study to assess the effects of multiple dose of pitavastatin (Livalo®) on steady-state warfarin in healthy adult volunteers. XV International Symposium on Atherosclerosis 2009. 14-18 June 2009, Boston, MA, USA. Atheroscler. Suppl. 10(2), P493 (2009).
    • (2009) Atheroscler. Suppl. , vol.10 , Issue.2
    • Inagaki, Y.1    Hunt, T.2    Arana, B.3
  • 31
    • 0033758172 scopus 로고    scopus 로고
    • NK-104: A novel synthetic HMG-CoA reductase inhibitors
    • Kajinami K, Mabushi H, Saito Y. NK-104: a novel synthetic HMG-CoA reductase inhibitors. Exp. Opin. Invest. Drugs 9(11), 2653-2661 (2000).
    • (2000) Exp. Opin. Invest. Drugs , vol.9 , Issue.11 , pp. 2653-2661
    • Kajinami, K.1    Mabushi, H.2    Saito, Y.3
  • 32
    • 0036231636 scopus 로고    scopus 로고
    • Clinical efficacy of pitavastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in patients with hyperlipidemia
    • Saito Y, Yamada N, Teramoto T et al. Clinical efficacy of pitavastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in patients with hyperlipidemia. Arzneimittelforschung 52, 251-255 (2002).
    • (2002) Arzneimittelforschung , vol.52 , pp. 251-255
    • Saito, Y.1    Yamada, N.2    Teramoto, T.3
  • 33
    • 0036234655 scopus 로고    scopus 로고
    • A randomized, double-blind trial comparing the efficacy and safety of pitavastatin versus pravastatin in patients with primary hypercholesterolemia
    • Saito Y, Yamada N, Teramoto T, Itakura H et al. A randomized, double-blind trial comparing the efficacy and safety of pitavastatin versus pravastatin in patients with primary hypercholesterolemia. Atherosclerosis 162(2), 373-379 (2002).
    • (2002) Atherosclerosis , vol.162 , Issue.2 , pp. 373-379
    • Saito, Y.1    Yamada, N.2    Teramoto, T.3    Itakura, H.4
  • 34
    • 0033984189 scopus 로고    scopus 로고
    • Effects of NK-104, a new hydroxymethylglutaryl- coenzyme reductase inhibitor, on low-density lipoprotein cholesterol in heterozygous familial hypercholesterolemia
    • Hokuriku NK-104 study group
    • Kajinami K, Koizumi J, Ueda K et al.; Hokuriku NK-104 study group. Effects of NK-104, a new hydroxymethylglutaryl- coenzyme reductase inhibitor, on low-density lipoprotein cholesterol in heterozygous familial hypercholesterolemia. Am. J. Cardiol. 85(2), 178-183 (2000).
    • (2000) Am. J. Cardiol. , vol.85 , Issue.2 , pp. 178-183
    • Kajinami, K.1    Koizumi, J.2    Ueda, K.3
  • 35
    • 0036015997 scopus 로고    scopus 로고
    • Hokuriku NK-104 study group. Long-term treatment with pitavastatin (NK-104), a new HMG-CoA reductase inhibitor, of patients with heterozygous familial hypercholesterolemia
    • Noji Y, Higashikata T, Inazu A et al.; Hokuriku NK-104 study group. Long-term treatment with pitavastatin (NK-104), a new HMG-CoA reductase inhibitor, of patients with heterozygous familial hypercholesterolemia. Atherosclerosis 163(1), 157-164 (2002).
    • (2002) Atherosclerosis , vol.163 , Issue.1 , pp. 157-164
    • Noji, Y.1    Higashikata, T.2    Inazu, A.3
  • 36
    • 18644373317 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitor decreases small dense low-density lipoprotein and remnant-like particle cholesterol in patients with Type 2 diabetes
    • Sone H, Takahashi A, Shimano H et al. HMG-CoA reductase inhibitor decreases small dense low-density lipoprotein and remnant-like particle cholesterol in patients with Type 2 diabetes. Life Sci. 71(20), 2403-2412 (2002).
    • (2002) Life Sci. , vol.71 , Issue.20 , pp. 2403-2412
    • Sone, H.1    Takahashi, A.2    Shimano, H.3
  • 37
    • 24344456373 scopus 로고    scopus 로고
    • A randomized, open-label study to evaluate the efficacy and safety of pitavastatin compared with simvastatin in Korean patients with hypercholesterolemia
    • Park S, Kang HJ, Rim SJ et al. A randomized, open-label study to evaluate the efficacy and safety of pitavastatin compared with simvastatin in Korean patients with hypercholesterolemia. Clin. Ther. 27, 1074-1082 (2005).
    • (2005) Clin. Ther. , vol.27 , pp. 1074-1082
    • Park, S.1    Kang, H.J.2    Rim, S.J.3
  • 38
    • 67249088838 scopus 로고    scopus 로고
    • Pitavastatin compared with atorvastatin in primary hypercholesterolemia or combined dyslipidemia
    • Budinski D, Arneson V, Hounslow N, Gratsiansky N. Pitavastatin compared with atorvastatin in primary hypercholesterolemia or combined dyslipidemia. Clin. Lipidol. 4(3), 291-302 (2009).
    • (2009) Clin. Lipidol. , vol.4 , Issue.3 , pp. 291-302
    • Budinski, D.1    Arneson, V.2    Hounslow, N.3    Gratsiansky, N.4
  • 39
    • 72549107976 scopus 로고    scopus 로고
    • Comparison of pitavastatin with simvastatin in primary hypercholesterolemia or combined dyslipidemia
    • Ose L, Budinski D, Hounslow N, Arneson V. Comparison of pitavastatin with simvastatin in primary hypercholesterolemia or combined dyslipidemia. Curr. Med. Res. Opin. 25(10), 2755-2764 (2009).
    • (2009) Curr. Med. Res. Opin. , vol.25 , Issue.10 , pp. 2755-2764
    • Ose, L.1    Budinski, D.2    Hounslow, N.3    Arneson, V.4
  • 40
    • 52949154682 scopus 로고    scopus 로고
    • A large-scale, long-term, prospective post-marketing surveillance of pitavastatin: LIVALO effectiveness and safety (LIVES) study
    • Kurihara Y, Douzono T, Kawakita K. A large-scale, long-term, prospective post-marketing surveillance of pitavastatin: LIVALO effectiveness and safety (LIVES) study. Jpn Pharmacol. Ther. 36(8), 709-731 (2008).
    • (2008) Jpn Pharmacol. Ther. , vol.36 , Issue.8 , pp. 709-731
    • Kurihara, Y.1    Douzono, T.2    Kawakita, K.3
  • 41
    • 77949479227 scopus 로고    scopus 로고
    • New evidence on pitavastatin: Efficacy and safety in clinical studies
    • Teramoto T, Shimano H, Yokote K, Urashima M. New evidence on pitavastatin: efficacy and safety in clinical studies. Expert Opin. Pharmacother. 11(5), 817-828 (2010).
    • (2010) Expert Opin. Pharmacother. , vol.11 , Issue.5 , pp. 817-828
    • Teramoto, T.1    Shimano, H.2    Yokote, K.3    Urashima, M.4
  • 42
    • 56649111325 scopus 로고    scopus 로고
    • Multicenter collaborative randomized parallel group comparative study of pitavastatin and atorvastatin in Japanese hypercholesterolemic patients. Collaborative study on hypercholesterolemia drug intervention and their benefits for atherosclerosis prevention (CHIBA study)
    • Yokote K, Bujo H, Hanaoka H et al. Multicenter collaborative randomized parallel group comparative study of pitavastatin and atorvastatin in Japanese hypercholesterolemic patients. Collaborative study on hypercholesterolemia drug intervention and their benefits for atherosclerosis prevention (CHIBA study). Atherosclerosis 201, 345-352 (2008).
    • (2008) Atherosclerosis , vol.201 , pp. 345-352
    • Yokote, K.1    Bujo, H.2    Hanaoka, H.3
  • 43
    • 59149099204 scopus 로고    scopus 로고
    • Effects of pitavastatin on lipid profiles and high-sensitivity CRP in Japanese subjects with hypercholesterolemia: Kansai investigation of statin for hyperlipidemic intervention in metabolism and endocrinology (KISHIMEN) investigators
    • Koshiyama H, Taniguchi A, Tanaka K et al.;Effects of pitavastatin on lipid profiles and high-sensitivity CRP in Japanese subjects with hypercholesterolemia: Kansai investigation of statin for hyperlipidemic intervention in metabolism and endocrinology (KISHIMEN) investigators. J. Atheroscler. Thromb. 15, 345-350(2008)
    • (2008) J. Atheroscler. Thromb. , vol.15 , pp. 345-350
    • Koshiyama, H.1    Taniguchi, A.2    Tanaka, K.3
  • 44
    • 47149104736 scopus 로고    scopus 로고
    • A 52-week, randomized, open-label, parallel-group comparison of the tolerability and effects of pitavastatin and atorvatatin on high-density lipoprotein cholesterol levels and glucose metabolism in Japanese patients with elevated levels of low-density lipoprotein cholesterol and glucose intolerance
    • Sasaki J, Ikeda Y, Kuribayashi T et al. A 52-week, randomized, open-label, parallel-group comparison of the tolerability and effects of pitavastatin and atorvatatin on high-density lipoprotein cholesterol levels and glucose metabolism in Japanese patients with elevated levels of low-density lipoprotein cholesterol and glucose intolerance. Clin. Ther. 30, 1089-1101 (2008).
    • (2008) Clin. Ther. , vol.30 , pp. 1089-1101
    • Sasaki, J.1    Ikeda, Y.2    Kuribayashi, T.3
  • 45
    • 67650095320 scopus 로고    scopus 로고
    • Effect of intensive statin therapy on regression of coronary atherosclerosis in patients with acute coronary syndrome
    • Hiro T, Kimura T, Morimoto T et al. Effect of intensive statin therapy on regression of coronary atherosclerosis in patients with acute coronary syndrome. J. Am. Coll. Cardiol. 54(4), 293-302 (2009).
    • (2009) J. Am. Coll. Cardiol. , vol.54 , Issue.4 , pp. 293-302
    • Hiro, T.1    Kimura, T.2    Morimoto, T.3
  • 46
    • 42449116679 scopus 로고    scopus 로고
    • Rapid stabilization of vulnerable carotid plaque within 1 month of pitavastatin treatment in patients with acute coronary syndrome
    • Nakamura T, Obata JE, Kitta Y et al. Rapid stabilization of vulnerable carotid plaque within 1 month of pitavastatin treatment in patients with acute coronary syndrome. J. Cardiovasc. Pharmacol. 51(4), 365-371 (2008).
    • (2008) J. Cardiovasc. Pharmacol. , vol.51 , Issue.4 , pp. 365-371
    • Nakamura, T.1    Obata, J.E.2    Kitta, Y.3
  • 47
    • 17344385356 scopus 로고    scopus 로고
    • The effect of statins on mRNA levels of genes related to inflammation, coagulation, and vascular constriction in HUVEC
    • Morikawa S, Takabe W, Mataki C et al. The effect of statins on mRNA levels of genes related to inflammation, coagulation, and vascular constriction in HUVEC. J. Atheroscler. Thromb. 9(4), 178-183 (2002).
    • (2002) J. Atheroscler. Thromb. , vol.9 , Issue.4 , pp. 178-183
    • Morikawa, S.1    Takabe, W.2    Mataki, C.3
  • 48
    • 33747884357 scopus 로고    scopus 로고
    • Pitavastatin attenuates the PDGF-induced LR11/uPA receptor-mediated migration of smooth muscle cells
    • Jiang M, Bujo H, Zhu Y et al. Pitavastatin attenuates the PDGF-induced LR11/uPA receptor-mediated migration of smooth muscle cells. Biochem. Biophys. Res. Commun. 348, 1367-1377 (2006).
    • (2006) Biochem. Biophys. Res. Commun. , vol.348 , pp. 1367-1377
    • Jiang, M.1    Bujo, H.2    Zhu, Y.3
  • 49
    • 33846276947 scopus 로고    scopus 로고
    • Pitavastatin inhibits lysophosphatidic acid-induced proliferation and monocyte chemoattractant protein-1 expression in aortic smooth muscle cells by suppressing Rac-1-mediated reactive oxygen species generation
    • Kaneyuki U, Ueda S, Yamagishi S et al. Pitavastatin inhibits lysophosphatidic acid-induced proliferation and monocyte chemoattractant protein-1 expression in aortic smooth muscle cells by suppressing Rac-1-mediated reactive oxygen species generation. Vascul. Pharmacol. 46, 286-292 (2007).
    • (2007) Vascul. Pharmacol. , vol.46 , pp. 286-292
    • Kaneyuki, U.1    Ueda, S.2    Yamagishi, S.3
  • 50
    • 40449094135 scopus 로고    scopus 로고
    • Effect of pitavastatin on macrophage cholesterol metabolism
    • Akisato Y, Ishii I. Effect of pitavastatin on macrophage cholesterol metabolism. Yakugaku Zasshi 128, 357-363 (2008).
    • (2008) Yakugaku Zasshi , vol.128 , pp. 357-363
    • Akisato, Y.1    Ishii, I.2
  • 51
    • 42149193750 scopus 로고    scopus 로고
    • Effects of statins on adipose tissue inflammation: Their inhibitory effect on M YD 8 8 -indep endent IRF3/IFN b pathway in macrophages
    • Abe M, Matsuda M, Kobayashi H et al. Effects of statins on adipose tissue inflammation: their inhibitory effect on M YD 8 8 -indep endent IRF3/IFN b pathway in macrophages. Arterioscler. Thromb. Vasc. Biol. 28, 871-877 (2008).
    • (2008) Arterioscler. Thromb. Vasc. Biol. , vol.28 , pp. 871-877
    • Abe, M.1    Matsuda, M.2    Kobayashi, H.3
  • 52
    • 0035929257 scopus 로고    scopus 로고
    • Pitavastatin enhanced BMP-2 and osteocalcin expression by inhibition of Rho-associated kinase in human osteoblasts
    • Ohnaka K, Shimoda S, Nawata H et al. Pitavastatin enhanced BMP-2 and osteocalcin expression by inhibition of Rho-associated kinase in human osteoblasts. Biochem. Biophys. Res. Commun. 287(2), 337-342 (2001).
    • (2001) Biochem. Biophys. Res. Commun. , vol.287 , Issue.2 , pp. 337-342
    • Ohnaka, K.1    Shimoda, S.2    Nawata, H.3
  • 53
    • 1242336795 scopus 로고    scopus 로고
    • Pitavastatin downregulates expression of the macrophage type B scavenger receptor, CD36
    • Han J, Zhou X, Yokoyama T, Hajjar DP, Gotto AM, Nicholson AC. Pitavastatin downregulates expression of the macrophage type B scavenger receptor, CD36. Circulation 109, 790-796 (2004).
    • (2004) Circulation , vol.109 , pp. 790-796
    • Han, J.1    Zhou, X.2    Yokoyama, T.3    Hajjar, D.P.4    Gotto, A.M.5    Nicholson, A.C.6
  • 54
    • 10044279170 scopus 로고    scopus 로고
    • Functional interplay between the macrophage scavenger receptor class B type i and pitavastatin (NK-104)
    • Han J, Parsons M, Zhou X, Nicholson AC, Gotto AM, Hajjar DP. Functional interplay between the macrophage scavenger receptor class B type I and pitavastatin (NK-104). Circulation 110, 3472-3479 (2004).
    • (2004) Circulation , vol.110 , pp. 3472-3479
    • Han, J.1    Parsons, M.2    Zhou, X.3    Nicholson, A.C.4    Gotto, A.M.5    Hajjar, D.P.6
  • 55
    • 61449119630 scopus 로고    scopus 로고
    • Pitavastatin suppresses mitogen activated protein kinase-mediated Erg-1 induction in human vascular smooth muscle cells
    • Lamon BD, Summers BD, Gotto AM, Hajjar DP. Pitavastatin suppresses mitogen activated protein kinase-mediated Erg-1 induction in human vascular smooth muscle cells. Eur. J. Pharmacol. 606, 72-76 (2009).
    • (2009) Eur. J. Pharmacol. , vol.606 , pp. 72-76
    • Lamon, B.D.1    Summers, B.D.2    Gotto, A.M.3    Hajjar, D.P.4
  • 56
    • 0041319490 scopus 로고    scopus 로고
    • Pitavastatin alters the expression of thrombotic and fibrinolytic proteins in human vascular cells
    • Markle RA, Han J, Summers BD. Pitavastatin alters the expression of thrombotic and fibrinolytic proteins in human vascular cells. J. Cell. Biochem. 90, 23-32 (2003).
    • (2003) J. Cell. Biochem. , vol.90 , pp. 23-32
    • Markle, R.A.1    Han, J.2    Summers, B.D.3
  • 57
    • 34447563762 scopus 로고    scopus 로고
    • Anti-adipogenic action of pitavastatin occurs through the coordinate regulation of PPARg and Pref-1 expression
    • Nicholson AC, Hajjar DP, Zhou X, He W, Gotto AM, Han J. Anti-adipogenic action of pitavastatin occurs through the coordinate regulation of PPARg and Pref-1 expression. Br. J. Pharmacol. 151, 807-815 (2007).
    • (2007) Br. J. Pharmacol. , vol.151 , pp. 807-815
    • Nicholson, A.C.1    Hajjar, D.P.2    Zhou, X.3    He, W.4    Gotto, A.M.5    Han, J.6
  • 58
    • 35748962429 scopus 로고    scopus 로고
    • The safety of statins in clinical practice
    • Armitage J. The safety of statins in clinical practice. Lancet 370(9601), 1781-1790 .
    • Lancet , vol.370 , Issue.9601 , pp. 1781-1790
    • Armitage, J.1
  • 59
    • 77549087054 scopus 로고    scopus 로고
    • Statins and risk of incident diabetes: A collaborative meta-analysis of randomized statin trials
    • Sattar N, Preiss D, Murray HM et al. Statins and risk of incident diabetes: a collaborative meta-analysis of randomized statin trials. Lancet 375(9716), 735-742 (2010).
    • (2010) Lancet , vol.375 , Issue.9716 , pp. 735-742
    • Sattar, N.1    Preiss, D.2    Murray, H.M.3
  • 60
    • 38049033935 scopus 로고    scopus 로고
    • Collaborators. Efficacy of cholesterol- lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: A meta-analysis
    • Cholesterol Treatment Trialists' (CTT)
    • Cholesterol Treatment Trialists' (CTT) Collaborators. Efficacy of cholesterol- lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis. Lancet 371, 117-125 .
    • Lancet , vol.371 , pp. 117-125
  • 61
    • 77952420085 scopus 로고    scopus 로고
    • Long-term treatment with pitavastatin is effective and well tolerated by patients with primary hypercholesterolemia or combined dyslipidemia
    • Ose L, Budinski D, Hounslow N, Arneson V. Long-term treatment with pitavastatin is effective and well tolerated by patients with primary hypercholesterolemia or combined dyslipidemia. Atherosclerosis 210(1), 202-208 (2010).
    • (2010) Atherosclerosis , vol.210 , Issue.1 , pp. 202-208
    • Ose, L.1    Budinski, D.2    Hounslow, N.3    Arneson, V.4
  • 62
    • 56749106312 scopus 로고    scopus 로고
    • JUPITER Study Group. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
    • Ridker PM, Danileson E, Fonseca FA et al.; JUPITER Study Group. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N. Engl. J. Med. 359(21), 2195-2207 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , Issue.21 , pp. 2195-2207
    • Ridker, P.M.1    Danileson, E.2    Fonseca, F.A.3
  • 63
    • 77955216937 scopus 로고    scopus 로고
    • Product information Pfizer, NY, USA
    • Product information. Lipitor (atorvastatin). Pfizer, NY, USA( 2009).
    • (2009) Lipitor (Atorvastatin)
  • 64
    • 77955207178 scopus 로고    scopus 로고
    • Product information Novartis Pharmaceuticals Corporation, NJ, USA
    • Product information. Lescol, Lescol XL (fluvastatin). Novartis Pharmaceuticals Corporation, NJ, USA (2006).
    • (2006) Lescol, Lescol XL (Fluvastatin)
  • 66
    • 77955213230 scopus 로고    scopus 로고
    • Product information Bristol-Myers Squibb, NJ, USA
    • Product information. Pravachol (pravastatin). Bristol-Myers Squibb, NJ, USA(2007).
    • (2007) Pravachol (Pravastatin)
  • 67
    • 77955215681 scopus 로고    scopus 로고
    • Product information AstraZeneca, DE, USA
    • Product information. Crestor (rosuvastatin). AstraZeneca, DE, USA (2010).
    • (2010) Crestor (Rosuvastatin)
  • 68
    • 77955179984 scopus 로고    scopus 로고
    • Product information Merck, NJ, USA
    • Product information. Zocor (simvastatin). Merck, NJ, USA(2008).
    • (2008) Zocor (Simvastatin)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.