A cloned pig model for examining atherosclerosis induced by high fat, high cholesterol diets

Animal Biotechnology

Volumn 21, Issue 3, 2010, Pages 179-187

  Jensen, Tor W ^a   Mazur, Meredith J ^a   Pettigew, James E ^a   Perez Mendoza, Victor G ^a   Zachary, James ^a   Schook, Lawrence B ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Atherosclerosis; Cholesterol; Cloned pig; Diet

Indexed keywords

ATHEROSCLEROSIS; CHOLESTEROL LEVELS; CLONED PIG; CORONARY HEART DISEASE; EXPERIMENTAL SYSTEM; GENETIC HETEROGENEITIES; METABOLIZABLE ENERGIES; SERUM CHOLESTEROL;

AMINO ACIDS; BLOOD VESSELS; CARDIOLOGY; CHOLESTEROL; DISEASES; MAMMALS; NUTRITION;

CLONING;

CHOLESTEROL; TRIACYLGLYCEROL; CHOLESTEROL INTAKE; FAT INTAKE;

ANIMAL; ANIMAL DISEASE; AORTA; ARTICLE; ATHEROSCLEROSIS; BLOOD; CHOLESTEROL INTAKE; CYTOCHEMISTRY; DISEASE MODEL; FAT INTAKE; FEMALE; METABOLISM; PATHOLOGY; RANDOMIZATION; SWINE; SWINE DISEASE; ADMINISTRATION AND DOSAGE; SWINE DISEASES; VETERINARY;

ANIMALS; AORTA; ATHEROSCLEROSIS; CHOLESTEROL; CHOLESTEROL, DIETARY; DIETARY FATS; DISEASE MODELS, ANIMAL; FEMALE; HISTOCYTOCHEMISTRY; RANDOM ALLOCATION; SWINE; SWINE DISEASES; TRIGLYCERIDES;

SUIDAE;

EID: 77955183496     PISSN: 10495398     EISSN: 15322378     Source Type: Journal    
DOI: 10.1080/10495398.2010.490693     Document Type: Article

References (25)

1. Hughes GC, et al. Translational physiology: Porcine models of human coronary artery disease: implications for preclinical trials of therapeutic angiogenesis. J Appl Physiol. 2003;94(5):1689-1701.
2. Jokinen MP, Clarkson TB, Prichard RW. Recent advances in molecular pathology - animal-models in atherosclerosis research. Exp Mol Path. 1985;42(1):1-28.
3. Hearse DJ. The elusive coypu: The importance of collateral flow and the search for an alternative to the dog. Cardiovascular Res. 2000;45(1):215-219.
4. Maxwell MP, Hearse DJ, Yellon DM. Species variation in the coronary collateral circulation during regional myocardial-ischemia - a critical determinant of the rate of evolution and extent of myocardial-infarction. Cardiovasc Res. 1987;21(10):737-746.
5. Schaper W, Jageneau A, Xhonneux R. The development of collateral circulation in the pig and dog heart. Cardiologia. 1967;51:321-335.
6. Fuchs S, et al. Transendocardial delivery of autologous bone marrow enhances collateral perfusion and regional function in pigs with chronic experimental myocardial ischemia. J Am Coll Cardiol. 2001;37(6):1726-1732.
7. Koch KC, et al. Effect of catheter-based transendocardial delivery of stromal cell-derived factor 1 alpha on left ventricular function and perfusion in a porcine model of myocardial infarction. Basic Res Cardiol. 2006;101(1):69-77.
8. Li RK, et al. Autologous porcine heart cell transplantation improved heart function after a myocardial infarction. J Thorac Cardiovasc Surg. 2000;119(1):62-68.
9. Makkar RR, et al. Intramyocardial injection of allogenic bone marrow-derived mesenchymal stem cells without immunosuppression preserves cardiac function in a porcine model of myocardial infarction. J Cardiovasc Pharmacol Ther. 2005;10(4):225-233.
10. Tomita S, et al. Improved heart function with myogenesis and angiogenesis after autologous porcine bone marrow stromal cell transplantation. J Thorac Cardiovasc Surg. 2002;123(6):1132-1140.
11. Yau TM, et al. Beneficial effect of autologous cell transplantation on infarcted heart function: Comparison between bone marrow stromal cells and heart cells. Ann Thorac Surg. 2003;75(1):169-176.
12. Bell FP, Gerrity RG. Evidence for an altered lipid metabolic state in circulating blood monocytes under conditions of hyperlipemia in swine and its implications in arterial lipid-metabolism. Arterioscler Throm. 1992;12(2):155-162.
13. Dixon JL, et al. Dyslipidemia and vascular dysfunction in diabetic pigs fed an atherogenic diet. Arterioscler Throm Vasc Biol. 1999;19(12):2981-2992.
14. Mahley RW, et al. Swine lipoproteins and atherosclerosis - changes in plasma lipoproteins and apoproteins induced by cholesterol feeding. Biochem. 1975;14(13):2817-2823.
15. Daoud AS, et al. Sequential morphologic studies of regression of advanced atherosclerosis. Arch Path Lab Med. 1981;105(5):233-239.
16. Ratcliff HI, Luginbuh H. Domestic pig - model for experimental atherosclerosis. Atheroscler. 1971;13(1):133-136.
17. Mahley RW. Apolipoprotein-E - cholesterol transport protein with expanding role in cell biology. Sci. 1988;240(4852):622-630.
18. Ramsoondar JJ, et al. Isolation and genetic characterization of the porcine apolipoprotein E gene. Anim Gen. 1998;29(1):43-47.
19. Brzozowska A, et al. The sequence of porcine apolipoprotein-E (Apoe) Cdna. DNA Sequence. 1993;4(3):207-210.
20. Davignon J, et al. Apolipoprotein E and atherosclerosis: Insight from animal and human studies. Clin Chim Acta. 1999;286(1-2):115-143.
21. Lusis AJ, Fogelman AM, Fonarow GC. Genetic basis of atherosclerosis: Part I - new genes and pathways. Circulation. 2004;110(13):1868-1873.
22. Peng DQ, et al. Gene-gene interaction of PPAR gamma and ApoE affects coronary heart disease risk. Int J Cardiol. 2003;92(2-3):257-263.
23. Nutrition Requirements of Swine: 10th Revised Edition. 1998. Subcommittee on Swine Nutrition; Committee on Animal Nutrition; National Research Council.
24. Marcoux C, et al. Plasma remnant-like particle lipid and apolipoprotein levels in normolipidemic and hyperlipidemic subjects. Atheroscler. 1998;139(1):161-171.
25. Royo T, et al. Effect of gemfibrozil on peripheral atherosclerosis and platelet activation in a pig model of hyperlipidemia. Eur J Clin Invest. 2000;30(10):843-852.