Otosclerosis: Disturbed balance between cell survival and apoptosis

Otology and Neurotology

Volumn 31, Issue 6, 2010, Pages 867-874

  Csomor, Péter ^a   Sziklai, István ^a   Liktor, Bálint ^b   Szabó, László Z ^b   Pytel, József ^c   Jóri, József ^d   Karosi, Tamás ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b BAJCSY ZSILINSZKY HOSPITAL   (Hungary)

^c UNIVERSITY OF PÉCS   (Hungary)

^d UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Apoptosis; Cell survival; Granzyme ; hCIAP1 2; Nonotosclerotic stapes fixation; Otosclerosis

Indexed keywords

BIOLOGICAL MARKER; GRANZYME; INHIBITOR OF APOPTOSIS PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANKYLOSIS; APOPTOSIS; ARTICLE; CELL SURVIVAL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MIDDLE AGED; OSTEOLYSIS; OTOSCLEROSIS; PATHOLOGY; PHYSIOLOGY; STAPES; STAPES SURGERY;

ADULT; AGED; ANKYLOSIS; APOPTOSIS; BIOLOGICAL MARKERS; BONE RESORPTION; CELL SURVIVAL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GRANZYMES; HUMANS; IMMUNOHISTOCHEMISTRY; INHIBITOR OF APOPTOSIS PROTEINS; MALE; MIDDLE AGED; OTOSCLEROSIS; STAPES; STAPES SURGERY; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 77955182934     PISSN: 15317129     EISSN: 15374505     Source Type: Journal    
DOI: 10.1097/MAO.0b013e3181e3dedf     Document Type: Article

References (30)

1. Chole RA, McKenna MJ. Patophysiology of otosclerosis. Otol Neurotol 2001;22:249Y57.
2. Arnold W, Niedermeyer HP, Lehn N, Neubert W, Hof̈ler H. Measles virus in otosclerosis and the specific immune response of the inner ear. Acta Otolaryngol (Stockh) 1996;116:705Y9. (Pubitemid 26332396)
3. McKenna MJ, Kristiansen AG, Haines J. Polymerase chain reaction amplification of measles virus sequence from human temporal bone sections with active otosclerosis. Am J Otol 1996;17:827Y30. (Pubitemid 26379243)
4. Karosi T, Kónya J, Szabó LZ, et al. Codetection of measles virus and tumor necrosis factorYalpha mRNA in otosclerotic stapes footplates. Laryngoscope 2005;115:1291Y7. (Pubitemid 40962373)
5. Karosi T, Jókay I, Kónya J, et al. Detection of osteoprotegerin and TNF-alpha mRNA in ankylotic stapes footplates in connection with measles virus positivity. Laryngoscope 2006;116:1427Y33. (Pubitemid 44181459)
6. Fujioka M, Kanzaki S, Okano HJ, Masuda M, Ogawa K, Okano H. Proinflammatory cytokines expression in noise-induced damaged cochlea. J Neurosci Res 2006;83:575Y83. (Pubitemid 43384851)
7. Papp Z, Rezes S, Jókay I, Sziklai I. Sensorineural hearing loss in chronic otitis media. Otol Neurotol 2003;24:141Y4. (Pubitemid 36337119)
8. Wajant H, Pfizenmaier K, Scheurich P. Tumor necrosis factor signaling. Cell Death Differ 2003;10:45Y65. (Pubitemid 36511832)
9. Chen G, Goeddel DV. TNF-R1 signaling: a beautiful pathway. Science 2002;296:1634Y5. (Pubitemid 34579145)
10. Karin M, Gallagher E. TNFR signaling: ubiquitin-conjugated TRAFfic signals control stop-and-go for MAPK signaling complexes. Immunol Rev 2009;228:225Y40.
11. Csomor P, Sziklai I, Karosi T. TNF-alpha receptor expression correlates with histologic activity of otosclerosis. Otol Neurotol 2009; 30:1131Y7.
12. Wang L, Du F, Wang X. TNF-alpha induces two distinct caspase-8 activation pathways. Cell 2008;133:693Y703. (Pubitemid 351636305)
13. Vince JE, Pantaki D, Feltham R, et al. TRAF2 must bind to cIAPs for TNF to efficiently activate NF-{kappa}B and to prevent TNFinduced apoptosis. J Biol Chem 2009;284:35906Y15.
14. Mahoney DJ, Cheung HH, Mrad RL, et al. Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation. Proc Natl Acad Sci U S A 2008;105:11778Y83.
15. Vischioni B, van der Valk P, Span SW, Kruyt FA, Rodriguez JA, Giaccone G. Expression and localization of inhibitor of apoptosis proteins in normal human tissues. Hum Pathol 2006;37:78Y86. (Pubitemid 41790506)
16. Bertrand MJ, Doiron K, Labbé K, Korneluk RG, Barker PA, Saleh M. Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2. Immunity 2009;30:789Y801.
17. Jin HS, Lee DH, Kim DH, Chung JH, Lee SJ, Lee TH. cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factorYkappaB activation. Cancer Res 2009;69:1782Y91.
18. Reardon C, Mak TW. cIAP proteins: keystones in NOD receptor signal transduction. Immunity 2009;30:755Y6.
19. Conte D, Holcik M, Lefebvre CA, et al. Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival. Mol Cell Biol 2006;26:699Y708. (Pubitemid 43090921)
20. Moumoulidis I, Axon P, Baguley D, Reid E. A review on the genetics of otosclerosis. Clin Otolaryngol 2007;32:239Y47. (Pubitemid 47101170)
21. Van Den Bogaert K, Govaerts PJ, De Leenheer EM, et al. Otosclerosis: a genetically heterogeneous disease involving at least three different genes. Bone 2002;30:624Y30. (Pubitemid 34270502)
22. Thys M, Van Den Bogaert K, Iliadou V, et al. A seventh locus for otosclerosis, OTSC7, maps to chromosome 6q13Y16.1. Eur J Hum Genet 2007;15:362Y8. (Pubitemid 46306533)
23. Bel Hadj Ali I, Thys M, Beltaief N, et al. A new locus for otosclerosis, OTSC8, maps to the pericentromeric region of chromosome 9. Hum Genet 2008;123:267Y72.
24. Karosi T, Szalmás A, Csomor P, Kónya J, Petkó M, Sziklai I. Disease-associated novel CD46 splicing variants and pathologic bone remodeling in otosclerosis. Laryngoscope 2008;118: 1669Y76.
25. Imauchi Y, Lombès M, Lainé P, Sterkers O, Ferrary E, Grayeli AB. Glucocorticoids inhibit diastrophic dysplasia sulfate transporter activity in otosclerosis by interleukin-6. Laryngoscope 2006;116: 1647Y50. (Pubitemid 44368088)
26. Lehnerdt G, Unkel C, Metz KA, Jahnke K, Neumann A. Immunohistochemical evidence of BMP-2, -4 and -7 activity in otospongiosis. Acta Otolaryngol 2008;128:13Y7.
27. Sziklai I. Human otosclerotic bone-derived peptide decreases the gain of the electromotility in isolated outer hair cells. Hear Res 1996;95:100Y7. (Pubitemid 26197914)
28. Satoh H, Firestein GS, Billings PB, Harris JP, Keithley EM. Tumor necrosis factorYalpha, an initiator, and etanercept, an inhibitor of cochlear inflammation. Laryngoscope 2002;112:1627Y34. (Pubitemid 34977568)
29. Cohen S, Shoup A, Weisman MH, Harris JP. Etanercept treatment for autoimmune inner ear disease: results of a pilot placebocontrolled study. Otol Neurotol 2005;26:903Y7. (Pubitemid 41330705)
30. Street I, Jobanputra P, Proops DW. Etanercept, a tumour necrosis factor alpha receptor antagonist, and methotrexate in acute sensorineural hearing loss. J Laryngol Otol 2006;120:1064Y6. (Pubitemid 46132593)