메뉴 건너뛰기




Volumn 148, Issue 2, 2010, Pages 125-130

Yasutomi Nishizuka: Father of protein kinase C

Author keywords

diacylglycerol; inositol turnover; lipid mediators; phorbol ester; protein kinase C

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; ADENOSINE TRIPHOSPHATE; CALCIUM IONOPHORE; CYCLIC AMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; PROTEIN KINASE C;

EID: 77955180125     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvq066     Document Type: Review
Times cited : (15)

References (39)
  • 2
    • 78651140129 scopus 로고
    • Studies on the biosynthesis of nicotinamide adenine dinucleotide. I. Enzymic synthesis of niacin ribonucleotides from 3-hydroxyanthranic acid in mammalian tissues
    • Nishizuka, Y. and Hayaishi, O. (1963) Studies on the biosynthesis of nicotinamide adenine dinucleotide. I. Enzymic synthesis of niacin ribonucleotides from 3-hydroxyanthranic acid in mammalian tissues. J. Biol. Chem. 238, 3369-3377
    • (1963) J. Biol. Chem. , vol.238 , pp. 3369-3377
    • Nishizuka, Y.1    Hayaishi, O.2
  • 3
    • 0014028950 scopus 로고
    • The interrelationship between guanosine triphosphatase and amino acid polymerization
    • Nishizuka, Y. and Lipmann, F. (1966) The interrelationship between guanosine triphosphatase and amino acid polymerization. Arch. Biochem. Biophys. 116, 344-351
    • (1966) Arch. Biochem. Biophys. , vol.116 , pp. 344-351
    • Nishizuka, Y.1    Lipmann, F.2
  • 4
    • 0014198717 scopus 로고
    • Studies on the polymer of adenosine diphosphate ribose. I. Enzymic formation from nicotinamide adenine dinuclotide in mammalian nuclei
    • Nishizuka, Y., Ueda, K., Nakazawa, K., and Hayaishi, O. (1967) Studies on the polymer of adenosine diphosphate ribose. I. Enzymic formation from nicotinamide adenine dinuclotide in mammalian nuclei. J. Biol. Chem. 242, 3164-3171
    • (1967) J. Biol. Chem. , vol.242 , pp. 3164-3171
    • Nishizuka, Y.1    Ueda, K.2    Nakazawa, K.3    Hayaishi, O.4
  • 5
    • 0014429772 scopus 로고
    • Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis
    • Honjo, T., Nishizuka, Y., Hayaishi, O., and Kato, I. (1968) Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis. J. Biol. Chem. 243, 3553-3555
    • (1968) J. Biol. Chem. , vol.243 , pp. 3553-3555
    • Honjo, T.1    Nishizuka, Y.2    Hayaishi, O.3    Kato, I.4
  • 6
    • 0014409394 scopus 로고
    • An adenosine 30,50-monophosphate-dependant protein kinase from rabbit skeletal muscle
    • Walsh, D.A., Perkins, J.P., and Krebs, E.G. (1968) An adenosine 30,50-monophosphate-dependant protein kinase from rabbit skeletal muscle. J. Biol. Chem. 243, 3763-3765
    • (1968) J. Biol. Chem. , vol.243 , pp. 3763-3765
    • Walsh, D.A.1    Perkins, J.P.2    Krebs, E.G.3
  • 7
    • 0014941715 scopus 로고
    • Adenosine 30,50-cyclic phosphate-dependent and independent histone kinases from rat liver
    • Yamamura, H., Takeda, M., Kumon, A., and Nishizuka, Y. (1970) Adenosine 30,50-cyclic phosphate-dependent and independent histone kinases from rat liver. Biochem. Biophys. Res. Commun. 40, 675-682
    • (1970) Biochem. Biophys. Res. Commun. , vol.40 , pp. 675-682
    • Yamamura, H.1    Takeda, M.2    Kumon, A.3    Nishizuka, Y.4
  • 8
    • 0014938581 scopus 로고
    • Mode of action of adenosine 30,50-cyclic phosphate on protein kinase from rat liver
    • Kumon, A., Yamamura, H., and Nishizuka, Y. (1970) Mode of action of adenosine 30,50-cyclic phosphate on protein kinase from rat liver. Biochem. Biophys. Res. Commun. 41, 1290-1297
    • (1970) Biochem. Biophys. Res. Commun. , vol.41 , pp. 1290-1297
    • Kumon, A.1    Yamamura, H.2    Nishizuka, Y.3
  • 9
    • 0014850393 scopus 로고
    • Mechanism of activation by adenosine 30 : 50-cyclic monophosphate of a protein phosphokinase from rabbit reticulocytes
    • Tao, M., Salas, M.L., and Lipmann, F. (1970) Mechanism of activation by adenosine 30 : 50-cyclic monophosphate of a protein phosphokinase from rabbit reticulocytes. Proc. Natl Acad. Sci. USA 67, 408-414
    • (1970) Proc. Natl Acad. Sci. USA , vol.67 , pp. 408-414
    • Tao, M.1    Salas, M.L.2    Lipmann, F.3
  • 10
    • 0015042684 scopus 로고
    • Role of the receptor in the mechanism of action of adenosine 30 : 50- cyclic monophosphate
    • Gill, G.N. and Garren, L.D. (1971) Role of the receptor in the mechanism of action of adenosine 30 : 50- cyclic monophosphate. Proc. Natl Acad. Sci. USA 68, 786-790
    • (1971) Proc. Natl Acad. Sci. USA , vol.68 , pp. 786-790
    • Gill, G.N.1    Garren, L.D.2
  • 11
    • 0015235782 scopus 로고
    • Separation of regulatory and catalytic subunits of the cyclic 30,50-adenosine monophosphate-dependent protein kinase(s) of rabbit skeletal muscle
    • Reimann, E.M., Brostrom, C.O., Corbin, J.D., King, C.A., and Krebs, E.G. (1971) Separation of regulatory and catalytic subunits of the cyclic 30,50-adenosine monophosphate-dependent protein kinase(s) of rabbit skeletal muscle. Biochem. Biophys. Res. Commun. 42, 187-194
    • (1971) Biochem. Biophys. Res. Commun. , vol.42 , pp. 187-194
    • Reimann, E.M.1    Brostrom, C.O.2    Corbin, J.D.3    King, C.A.4    Krebs, E.G.5
  • 12
    • 0017155056 scopus 로고
    • Guanosine 30,50-monophosphate-dependent protein kinase from silk worm, properties of a catalytic fragment obtained by limited proteolysis
    • Inoue, M., Kishimoto, A., Takai, Y., and Nishizuka, Y. (1976) Guanosine 30,50-monophosphate-dependent protein kinase from silk worm, properties of a catalytic fragment obtained by limited proteolysis. J. Biol. Chem. 251, 4476-4478
    • (1976) J. Biol. Chem. , vol.251 , pp. 4476-4478
    • Inoue, M.1    Kishimoto, A.2    Takai, Y.3    Nishizuka, Y.4
  • 13
    • 0017716047 scopus 로고
    • Studies on a cyclic nycleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calciumdependent protease from rat brain
    • Inoue, M., Kishimoto, A., Takai, Y., and Nishizuka, Y. (1977) Studies on a cyclic nycleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calciumdependent protease from rat brain. J. Biol. Chem. 252, 7610-7616
    • (1977) J. Biol. Chem. , vol.252 , pp. 7610-7616
    • Inoue, M.1    Kishimoto, A.2    Takai, Y.3    Nishizuka, Y.4
  • 14
    • 0018803639 scopus 로고
    • Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system
    • Takai, Y., Kishimoto, A., Kikkawa, U., Mori, M., and Nishizuka, Y. (1979) Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system. Biochem. Biophys. Res. Commun. 91, 1218-1224
    • (1979) Biochem. Biophys. Res. Commun. , vol.91 , pp. 1218-1224
    • Takai, Y.1    Kishimoto, A.2    Kikkawa, U.3    Mori, M.4    Nishizuka, Y.5
  • 15
    • 0019332349 scopus 로고
    • Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover
    • Kishimoto, A., Takai, Y., Mori, M., Kikkawa, U., and Nishizuka, Y. (1980) Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover. J. Biol. Chem. 255, 2273-2276
    • (1980) J. Biol. Chem. , vol.255 , pp. 2273-2276
    • Kishimoto, A.1    Takai, Y.2    Mori, M.3    Kikkawa, U.4    Nishizuka, Y.5
  • 16
    • 84960994832 scopus 로고
    • Enzyme secretion and incorporation of 32P into phospholipids of pancreatic slices
    • Hokin, M.R. and Hokin, L.E. (1953) Enzyme secretion and incorporation of 32P into phospholipids of pancreatic slices. J. Biol. Chem. 203, 967-977
    • (1953) J. Biol. Chem. , vol.203 , pp. 967-977
    • Hokin, M.R.1    Hokin, L.E.2
  • 17
    • 0018363176 scopus 로고
    • Production of diacyglyceride from phosphatidylinositol in activated human platelets
    • Rittenhouse-Simmons, R. (1979) Production of diacyglyceride from phosphatidylinositol in activated human platelets. J. Clin. Invest. 63, 580-587
    • (1979) J. Clin. Invest. , vol.63 , pp. 580-587
    • Rittenhouse-Simmons, R.1
  • 18
    • 0016764133 scopus 로고
    • Thrombin-induced protein phosphorylation in human plaetelets
    • Lyons, R.M., Stanford, N., and Majerus, P.W. (1975) Thrombin-induced protein phosphorylation in human plaetelets. J. Clin. Invest. 56, 924-936
    • (1975) J. Clin. Invest. , vol.56 , pp. 924-936
    • Lyons, R.M.1    Stanford, N.2    Majerus, P.W.3
  • 19
    • 0017393127 scopus 로고
    • Relationship between phosphorylations of blood platelet proteins and secretion of platelet granule constituents. I. Effects of different aggregating agents
    • Haslum, R.J. and Lynham, J.A. (1977) Relationship between phosphorylations of blood platelet proteins and secretion of platelet granule constituents. I. Effects of different aggregating agents. Biochem. Biophys. Res. Commun. 77, 714-722
    • (1977) Biochem. Biophys. Res. Commun. , vol.77 , pp. 714-722
    • Haslum, R.J.1    Lynham, J.A.2
  • 20
    • 0019298511 scopus 로고
    • Phospholipid turnover as a possible transmembrane signal for protein phosphorylation during human platelet activation by thrombin
    • Kawahara, Y., Takai, Y., Minakuchi, R., Sano, K., and Nishizuka, Y. (1980) Phospholipid turnover as a possible transmembrane signal for protein phosphorylation during human platelet activation by thrombin. Biochem. Biophys. Res. Commun. 97, 309-317
    • (1980) Biochem. Biophys. Res. Commun. , vol.97 , pp. 309-317
    • Kawahara, Y.1    Takai, Y.2    Minakuchi, R.3    Sano, K.4    Nishizuka, Y.5
  • 21
    • 0020962197 scopus 로고
    • Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation
    • Kaibuchi, K., Takai, Y., Sawamura, M., Hoshijima, M., Fujikura, T., and Nishizuka, Y. (1983) Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation. J. Biol. Chem. 258, 6701-6704
    • (1983) J. Biol. Chem. , vol.258 , pp. 6701-6704
    • Kaibuchi, K.1    Takai, Y.2    Sawamura, M.3    Hoshijima, M.4    Fujikura, T.5    Nishizuka, Y.6
  • 22
    • 0016613531 scopus 로고
    • Inositol phospholipids and cell surface receptor function
    • Michell, R.H. (1975) Inositol phospholipids and cell surface receptor function. Biochim. Biophys. Acta 415, 81-147
    • (1975) Biochim. Biophys. Acta , vol.415 , pp. 81-147
    • Michell, R.H.1
  • 23
    • 0020643801 scopus 로고
    • Release of Ca2+ from a nonmitochodrial intracellular store in pancreatic ascinar cells by inositol-1,4, 5-trisphosphate
    • Streb, H., Irvine, R.F., Berridge, M.J., and Schlutz, I. (1983) Release of Ca2+ from a nonmitochodrial intracellular store in pancreatic ascinar cells by inositol-1,4, 5-trisphosphate. Nature 306, 67-69
    • (1983) Nature , vol.306 , pp. 67-69
    • Streb, H.1    Irvine, R.F.2    Berridge, M.J.3    Schlutz, I.4
  • 24
    • 0020326790 scopus 로고
    • Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters
    • Castagna, M., Takai, Y., Kaibuchi, K., Sano, K., Kikkawa, U., and Nishizuka, Y. (1982) Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J. Biol. Chem. 257, 7847-7851
    • (1982) J. Biol. Chem. , vol.257 , pp. 7847-7851
    • Castagna, M.1    Takai, Y.2    Kaibuchi, K.3    Sano, K.4    Kikkawa, U.5    Nishizuka, Y.6
  • 25
    • 0020634260 scopus 로고
    • Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters
    • Kikkawa, U., Takai, Y., Tanaka, Y., Miyake, R., and Nishizuka, Y. (1983) Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters. J. Biol. Chem. 258, 11442-11445
    • (1983) J. Biol. Chem. , vol.258 , pp. 11442-11445
    • Kikkawa, U.1    Takai, Y.2    Tanaka, Y.3    Miyake, R.4    Nishizuka, Y.5
  • 27
    • 0021227676 scopus 로고
    • The role of protein kinase C in cell surface signal transduction and tumour promotion
    • Nishizuka, Y. (1984) The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature 308, 693-698
    • (1984) Nature , vol.308 , pp. 693-698
    • Nishizuka, Y.1
  • 28
    • 0023052241 scopus 로고
    • Studies and perspectives of protein kinase C
    • Nishizuka, Y. (1986) Studies and perspectives of protein kinase C. Science 233, 305-312
    • (1986) Science , vol.233 , pp. 305-312
    • Nishizuka, Y.1
  • 29
    • 0036773777 scopus 로고    scopus 로고
    • Protein kinase C isotypes and their specific functions: Prologue
    • Ohno, S. and Nishizuka, Y. (2002) Protein kinase C isotypes and their specific functions: prologue. J. Biochem. 132, 509-511
    • (2002) J. Biochem. , vol.132 , pp. 509-511
    • Ohno, S.1    Nishizuka, Y.2
  • 30
    • 0032104245 scopus 로고    scopus 로고
    • The extended protein kinase C superfamily
    • Mellor, H. and Parker, P.J. (1998) The extended protein kinase C superfamily. Biochem. J. 332, 281-292
    • (1998) Biochem. J. , vol.332 , pp. 281-292
    • Mellor, H.1    Parker, P.J.2
  • 32
    • 0027332733 scopus 로고
    • Expression of an oncogenic rasHa gene in murine keratinocytes induces tyrosine phosphorylation and reduced activity of protein kinase C delta
    • Denning, M.F., Dlugosz, A.A., Howett, M.K., and Yuspa, S.H. (1993) Expression of an oncogenic rasHa gene in murine keratinocytes induces tyrosine phosphorylation and reduced activity of protein kinase C delta. J. Biol. Chem. 268, 26079-26081
    • (1993) J. Biol. Chem. , vol.268 , pp. 26079-26081
    • Denning, M.F.1    Dlugosz, A.A.2    Howett, M.K.3    Yuspa, S.H.4
  • 33
    • 0031466995 scopus 로고    scopus 로고
    • Direct visualization of the translocation of the gamma-subspecies of protein kinase C in living cells using fusion proteins with green fluorescent protein
    • Sakai, N., Sasaki, K., Ikegaki, N., Shirai, Y., Ono, Y., and Saito, N. (1997) Direct visualization of the translocation of the gamma-subspecies of protein kinase C in living cells using fusion proteins with green fluorescent protein. J. Cell Biol 139, 1465-1476
    • (1997) J. Cell Biol , vol.139 , pp. 1465-1476
    • Sakai, N.1    Sasaki, K.2    Ikegaki, N.3    Shirai, Y.4    Ono, Y.5    Saito, N.6
  • 34
    • 1542757525 scopus 로고    scopus 로고
    • Animal models in the study of protein kinase C isozymes
    • Choi, D.S. and Messing, R.O. (2003) Animal models in the study of protein kinase C isozymes. Methods Mol. Biol. 233, 455-473
    • (2003) Methods Mol. Biol. , vol.233 , pp. 455-473
    • Choi, D.S.1    Messing, R.O.2
  • 36
    • 27844539756 scopus 로고    scopus 로고
    • Protein kinase C and the regulation of the actin cytoskeleton
    • Larsson, C. (2006) Protein kinase C and the regulation of the actin cytoskeleton. Cell. Signal. 18, 276-284
    • (2006) Cell. Signal. , vol.18 , pp. 276-284
    • Larsson, C.1
  • 37
    • 62849107572 scopus 로고    scopus 로고
    • Neuroprotective versus tumorigenic protein kinase C activators
    • Nelson, T.J. and Alkon, D.L. (2009) Neuroprotective versus tumorigenic protein kinase C activators. Trends Biochem. Sci. 34, 136-145
    • (2009) Trends Biochem. Sci. , vol.34 , pp. 136-145
    • Nelson, T.J.1    Alkon, D.L.2
  • 38
    • 0028260497 scopus 로고
    • Lipid mediator and protein kinase C activation for the intracellular signaling network
    • Nakamura, S. and Nishizuka, Y. (1994) Lipid mediator and protein kinase C activation for the intracellular signaling network. J. Biochem. 115, 1029-1034.
    • (1994) J. Biochem. , vol.115 , pp. 1029-1034
    • Nakamura, S.1    Nishizuka, Y.2
  • 39
    • 56949105142 scopus 로고    scopus 로고
    • Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system
    • Okada, T., Kajimoto, T., Jahangeer, S., and Nakamura, S. (2009) Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system. Cell. Signal. 21, 7-13
    • (2009) Cell. Signal. , vol.21 , pp. 7-13
    • Okada, T.1    Kajimoto, T.2    Jahangeer, S.3    Nakamura, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.