Lower limb osteoarthritis: Biomechanical alterations and implications for therapy

Current Opinion in Rheumatology

Volumn 22, Issue 5, 2010, Pages 544-550

  Block, Joel A ^a   Shakoor, Najia ^a  

^a RUSH MEDICAL COLLEGE   (United States)

Author keywords

biomechanics; joint loading; osteoarthritis

Indexed keywords

ANALGESIC AGENT;

BIOMECHANICS; DISEASE COURSE; GAIT; HUMAN; KNEE OSTEOARTHRITIS; PHYSIOTHERAPY; PRIORITY JOURNAL; REVIEW; BRACE; KINESIOTHERAPY; ORTHOSIS; OSTEOARTHRITIS, KNEE; PATHOPHYSIOLOGY; PHYSIOLOGY; WEIGHT BEARING;

BIOMECHANICS; BRACES; EXERCISE THERAPY; GAIT; HUMANS; ORTHOTIC DEVICES; OSTEOARTHRITIS, KNEE; WEIGHT-BEARING; BIOMECHANICAL PHENOMENA;

EID: 77955177011     PISSN: 10408711     EISSN: None     Source Type: Journal    
DOI: 10.1097/BOR.0b013e32833bd81f     Document Type: Review

References (75)

1. Slemenda C, Brandt KD, Heilman DK, et al. Quadriceps weakness and osteoarthritis of the knee. Ann Intern Med 1997; 127:97-104.
2. Pai YC, Rymer WZ, Chang RW, Sharma L. Effect of age and osteoarthritis on knee proprioception. Arthritis Rheum 1997; 40:2260-2265.
3. Hurley MV, Rees J, Newham DJ. Quadriceps function, proprioceptive acuity and functional performance in healthy young, middle-aged and elderly subjects. Age Aging 1998; 27:55-62.
4. Shakoor N, Agrawal A, Block JA. Reduced lower extremity vibratory perception in osteoarthritis of the knee. Arthritis Rheum 2008; 59:117-121.
5. Shakoor N, Lee KJ, Fogg LF, Block JA. Generalized vibratory deficits in osteoarthritis of the hip. Arthritis Care Res 2008; 59:1237-1240.
6. Segal NA, Glass NA, Torner J, et al. Quadriceps weakness predicts risk for knee joint space narrowing in women in the MOST cohort. Osteoarthritis and Cartilage 2010; 18:769-775.
7. Brandt KD. Neuromuscular aspects of osteoarthritis: a perspective. Novartis Found Symp 2004; 260:49-58.
8. Mikesky AE, MeyerA, ThompsonKL.Relationshipbetweenquadricepsstrength and rate of loading during gait in women. J Orthop Res 2000; 18:171-175.
9. Thorp LE, Wimmer MA, Block JA, et al. Bone mineral density in the proximal tibia varies as a function of static alignment and knee adduction angular momentum in individuals with medial knee osteoarthritis. Bone 2006; 39:1116-1122.
10. Hurwitz DE, Ryals AR, Case JP, et al. The knee adduction moment during gait in subjects with knee osteoarthritis is more closely correlated with static alignment than radiographic disease severity, toe out angle and pain. J Orthop Res 2002; 20:101-107.
11. Goker B, Block JA. Improved precision in quantifying knee alignment angle. Clin Orthop 2007; 458:145-149.
12. Tanamas S, Hanna FS, Cicuttini FM, et al. Does knee malalignment increase the risk of development and progression of knee osteoarthritis? A systematic review. Arthritis Rheum 2009; 61:459-467.
13. Sharma L, Song J, Felson DT, et al. The role of knee alignment in disease progression and functional decline in knee osteoarthritis. J Am Med Asoc 2001; 286:188-195.
14. Sharma L, Lou C, Felson DT, et al. Laxity in healthy and osteoarthritic knees. Arthritis Rheum 1999; 42:861-870.
15. Felson DT, Anderson JJ, Naimark A, et al. Obesity and knee osteoarthritis. The Framingham Study. Ann Intern Med 1988; 109:18-24.
16. Niu J, Zhang YQ, Torner J, et al. Is obesity a risk factor for progressive radiographic knee osteoarthritis? Arthritis Rheum 2009; 61:329-335.
17. Blagojevic M, Jinks C, Jeffery A, Jordan KP. Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis. Osteoarthritis Cartilage 2010; 18:24-33.
18. Sharma L, Lou C, Cahue S, Dunlop DD. The mechanism of the effect of obesity in knee osteoarthritis: the mediating role of malalignment. Arthritis Rheum 2000; 43:568-575.
19. Morrison JB. Bioengineering analysis of force actions transmitted by the knee joint. Bio-Med Engin 1968; 3:164.
20. Radin EL, Burr DB, Caterson B, et al. Mechanical determinants of osteoar-throsis. Semin Arthritis Rheum 1991; 21:12-21.
21. Andriacchi TP, Natarajan RN, Hurwitz DE. Musculoskeletal dynamics, locomotion, and clinical applications. In: Mow VC, Wilson CH, editors. Basic orthopaedic biomechanics, 2nd ed Philadelphia: Lippincott-Raven Publishers; 1997. pp. 37-68.
22. Harrington IJ. Static and dynamic loading patterns in knee joints with deformities. J Bone Joint Surg Am 1983; 65:247-259.
23. Schipplein OD, Andriacchi TP. Interaction between active and passive knee stabilizers during level walking. J Orthop Res 1991; 9:113-119.
24. Sharma L, Hurwitz DE, Thonar EJ, et al. Knee adduction moment, serum hyaluronan level, and disease severity in medial tibiofemoral osteoarthritis. Arthritis Rheum 1998; 41:1233-1240.
25. Prodromos CC, Andriacchi TP, Galante JO. A relationship between gait and clinical changes following high tibial osteotomy. J Bone Joint Surg Am 1985; 67:1188-1194.
26. Wang JW, Kuo KN, Andriacchi TP, Galante JO. The influence of walking mechanics and time on the results of proximal tibial osteotomy. J Bone Joint Surg Am 1990; 72:905-909.
27. Andrews M, Noyes FR, Hewett TE, Andriacchi TP. Lower limb alignment and foot angle are related to stance phase knee adduction in normal subjects: a critical analysis of the reliability of gait analysis data. J Orthop Res 1996; 14:289-295.
28. Thorp LE, Sumner DR, Wimmer MA, Block JA. Relationship between pain and medial knee joint loading in mild radiographic knee osteoarthritis. Arthritis Rheum 2007; 57:1254-1260.
29. Amin S, Luepongsak N, McGibbon CA, et al. Knee adduction moment and development of chronic knee pain in elders. Arthritis Rheum 2004; 51:371-376.
30. Miyazaki T, Wada M, Kawahara H, et al. Dynamic load at baseline can predict radiographic disease progression in medial compartment knee osteoarthritis. Ann Rheum Dis 2002; 61:617-622.
31. Thorp LE, Sumner DR, Block JA, et al. Knee joint loading differs in individuals with mild compared with moderate medial knee osteoarthritis. Arthritis Rheum 2006; 54:3842-3849.
32. Felson DT, Hannan MT, Naimark A, et al. Occupational physical demands, knee bending, and knee osteoarthritis: results from the Framingham Study. J Rheumatol 1991; 18:1587-1592.
33. Croft P, Cooper C, Wickham C, Coggon D. Osteoarthritis of the hip and occupational activity. Scand J Work Environ Health 1992; 18:59-63.
34. Shakoor N, Block JA, Shott S, Case JP. Nonrandom evolution of end-stage osteoarthritis of the lower limbs. Arthritis Rheum 2002; 46:3185-3189.
35. Shakoor N, Hurwitz DE, Block JA, etal. Asymmetric knee loading in advanced unilateral hip osteoarthritis. Arthritis Rheum 2003; 48:1556-1561.
36. Harvey WF, Yang M, Cooke TD, et al. Association of leg-length inequality with knee osteoarthritis: a cohort study. Ann Intern Med 2010; 152:287-295
37. American College of Rheumatology Subcommittee on Osteoarthritis Guidelines. Recommendations for the medical management of osteoarthritis of the hip and knee. 2000 update. Arthritis Rheum 2000; 43:1905-1915.
38. Dieppe PA, Lohmander LS. Pathogenesis and management of pain in osteoarthritis. Lancet 2005; 365:965-973.
39. Hurwitz DE, Ryals AR, Block JA, etal. Knee pain and joint loading in subjects with osteoarthritis of the knee. J Orthop Res 2000; 18:572-579.
40. Marius H, Thomas G, Jens A, et al. Gait changes in patients with knee osteoarthritis are replicated by experimental knee pain. Arthritis Care Res 2010; 62:501-509.
41. Schnitzer TJ, Popovich JM, Andersson GB, Andriacchi TP. Effect of piroxicam on gait in patients with osteoarthritis of the knee. Arthritis Rheum 1993; 36:1207-1213.
42. KempG, Crossley KM, WrigleyTV, etal. Reducing joint loading in medial knee osteoarthritis: shoes and canes. Arthritis Rheum 2008; 59:609-614.
43. Fregly BJ, D'Lima DD, Colwell CW Jr. Effective gait patterns for offloading the medial compartment of the knee. J Orthop Res 2009; 27:1016-1021.
44. Mundermann A, Dyrby CO, Hurwitz DE, etal. Potential strategies to reduce medial compartment loading in patients with knee osteoarthritis of varying severity: reduced walking speed. Arthritis Rheum 2004; 50:1172-1178.
45. Chang A, Hurwitz D, Dunlop D, et al. The relationship between toe-out angle during gait and progression of medial tibiofemoral osteoarthritis. Ann Rheum Dis 2007; 66:1271-1275.
46. Jenkyn TR, Hunt MA, Jones IC, et al. Toe-out gait in patients with knee osteoarthritis partially transforms external knee adduction moment into flexion moment during early stance phase of gait: a tri-planar kinetic mechanism. J Biomech 2008; 41:276-283.
47. Mundermann A, Asay JL, Mundermann L, Andriacchi TP. Implications of increased medio-lateral trunk sway for ambulatory mechanics. J Biomech 2008; 41:165-170.
48. Self BP, Greenwald RM, Pflaster DS. A biomechanical analysis of a medial unloading brace for osteoarthritis in the knee. Arthritis Care Res 2000; 13:191-197.
49. Lindenfeld TN, Hewett TE, Andriacchi TP. Joint loading with valgus bracing in patients with varus gonarthrosis. Clin Orthop Rel Res 1997; 344:290-297.
50. Brouwer RW, van Raaij TM, Verhaar JA, et al. Brace treatment for osteoarthritis of the knee: a prospective randomized multicentre trial. Osteoarthritis Cartilage 2006; 14:777-783.
51. Kirkley A, Webster-BogaertS, Litchfield R, etal. The effect of bracing on varus gonarthrosis. J Bone Joint Surg Am 1999; 81:539-548.
52. Pollo FE, Jackson RW. Knee bracing for unicompartmental osteoarthritis. J Am Acad Orthop Surg 2006; 14:5-11.
53. Beaudreuil J, BendayaS, Faucher M, etal. Clinical practice guidelines for rest orthosis, knee sleeves, and unloading knee braces in knee osteoarthritis. Joint, Bone, Spine: Revue du Rhum 2009; 76:629-636.
54. Stamenovic D, Kojic M, Stojanovic B, Hunter D. Pneumatic osteoarthritis knee brace. J Biomech Engin 2009; 131:045001.
55. Yasuda K, Sasaki T. The mechanics of treatment of the osteoarthritic knee with a wedged insole. Clin Orthop Rel Res 1987; 215:162-172.
56. Ogata K, Yasunaga M, Nomiyama H. The effect of wedged insoles on the thrust of osteoarthritic knees. Intern Orthop 1997; 21:308-312.
57. Kerrigan DC, Lelas JL, Goggins J, etal. Effectiveness of a lateral-wedge insole on knee varus torque in patients with knee osteoarthritis. Arch Phys Med Rehabil 2002; 83:889-893.
58. Hinman RS, Bowles KA, Bennell KL Laterally wedged insoles in knee osteoarthritis: do biomechanical effects decline after one month of wear? BMC Musculoskel Dis 2009; 10:146.
59. PhamT, Maillefert JF, Hudry C, etal. Laterally elevated wedged insoles in the treatment of medial knee osteoarthritis: a two-year prospective randomized controlled study. Osteoarthritis Cartilage 2004; 12:46-55.
60. Maillefert JF, Hudry C, Baron G, etal. Laterally elevated wedged insoles in the treatment of medial knee osteoarthritis: a prospective randomized controlled study. Osteoarthritis Cartilage 2001; 9:738-745.
61. Baker K, Goggins J, Xie H, et al. A randomized crossover trial of a wedged insole for treatment of knee osteoarthritis. Arthritis Rheum 2007; 56:1198-1203.
62. Toda Y, Tsukimura N, Kato A. The effects of different elevations of laterally wedged insoles with subtalar strapping on medial compartment osteoarthritis of the knee. Arch Phys Med Rehabil 2004; 85:673-677.
63. Shakoor N, Block JA. Walking barefoot decreases loading on the lower extremity joints in knee osteoarthritis. Arthritis Rheum 2006; 54:2923-2927.
64. Shakoor N, Sengupta M, Foucher KC, et al. The effects of common footwear on joint loading in osteoarthritis of the knee. Arthritis Care Res 2010 [Epub ahead of print, PMID: 20191571].
65. Kerrigan DC, Todd MK, Riley PO. Knee osteoarthritis and high-heeled shoes. Lancet 1998; 35:1399-1401.
66. Shakoor N, Lidtke RH, Sengupta M, et al. Effects of specialized footwear on joint loads in osteoarthritis of the knee. Arthritis Rheum 2008; 59:1214-1220.
67. Erhart JC, Mundermann A, Elspas B, et al. A variable-stiffness shoe lowers the knee adduction moment in subjects with symptoms of medial compartment knee osteoarthritis. J Biomech 2008; 41:2720-2725.
68. Erhart JC, Mundermann A, Elspas B, et al. Changes in knee adduction moment, pain, and functionality with a variable-stiffness walking shoe after 6 months. J Orthop Res 2010 [Epub ahead of print, PMID: 20058261].
69. Fransen M. Exercise for osteoarthritis of the knee. Cochrane Database Syst Rev 2009. doi: 10.1002/14651858. D004376. ub2.
70. Roddy E, Zhang W, Doherty M, et al. Evidence-based recommendations for the role of exercise in the management of osteoarthritis of the hip or knee: the MOVE consensus. Rheumatol 2005; 44:67-73.
71. Mundermann A, Dyrby CO, Andriacchi TP. Secondary gait changes in patients with medial compartment knee osteoarthritis: increased load at the ankle, knee, and hip during walking. Arthritis Rheum 2005; 52:2835-2844.
72. Mundermann A, Dyrby CO, Andriacchi TP. Hip abductor strength may be critical for successful gait compensation in patients with medial compartment knee osteoarthritis [abstract]. Intern J Biomech 2005. http://www.isb2005.org/ program/abstracts/0932. df.
73. Chang A, Hayes K, Dunlop D, et al. Hip abduction moment and protection against medial tibiofemoral osteoarthritis progression. Arthritis Rheum 2005; 52:3515-3519.
74. Thorp LE, Wimmer MA, Foucher KC, et al. The biomechanical effects of focused muscle training on medial knee loads in OA of the knee: a pilot, proof of concept study. JMNI 2010 (in press).
75. Bennell KL, Hunt MA, WrigleyTV, etal. Hip strengthening reduces symptoms but not knee load in people with medial knee osteoarthritis and varus malalignment: a randomised controlled trial. Osteoarthritis Cartilage 2010 [Epub ahead of print, PMID: 20175973].