In vivo measurement of the human epidermal thickness in different localizations by multiphoton laser tomography

Skin Research and Technology

Volumn 16, Issue 3, 2010, Pages 259-264

  Koehler, Martin Johannes ^a   Vogel, Tanja ^a   Elsner, Peter ^a   König, Karsten ^b   Bückle, Rainer ^c   Kaatz, Martin ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c JENLAB GMBH   (Germany)

Author keywords

Corneal layer; Epidermis; Multiphoton laser; Skin aging; Stratum corneum; Thickness

Indexed keywords

COHERENT LIGHT; TOMOGRAPHY;

AGE GROUPS; CONFOCAL LASER MICROSCOPY; CORNEAL LAYER; COSMETIC SCIENCE; DEPTH-RESOLVED; ETHICS COMMITTEE; IN-VIVO; IN-VIVO MEASUREMENT; MORPHOMETRIC PARAMETERS; MULTIPHOTON LASERS; MULTIPHOTONS; OPTICAL COHERENCE TOMOGRAPHY; PAPILLARY DERMIS; SIDE EFFECT; SKIN DISORDERS; STRATUM CORNEUM;

MEASUREMENTS;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DERMIS; EPIDERMIS; FOREARM; GROUPS BY AGE; HAND; HUMAN; IN VIVO STUDY; MORPHOMETRICS; MULTIPHOTON LASER TOMOGRAPHY; MULTIPHOTON MICROSCOPY; NORMAL HUMAN; SKIN EXAMINATION; SKINFOLD THICKNESS; STRATUM CORNEUM; TOMOGRAPHY; ALGORITHM; ANATOMY AND HISTOLOGY; CUTANEOUS PARAMETERS; DEVICES; DIAGNOSTIC USE; EPILUMINESCENCE MICROSCOPY; LASER; MIDDLE AGED; PATHOLOGY; PROCEDURES; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ALGORITHMS; DERMOSCOPY; EPIDERMIS; FOREARM; HAND; HUMANS; LASERS; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; MIDDLE AGED; SKIN AGING; YOUNG ADULT;

EID: 77955141341     PISSN: 0909752X     EISSN: 16000846     Source Type: Journal    
DOI: 10.1111/j.1600-0846.2010.00437.x     Document Type: Article

References (24)

1. Whitton JT, Everall JD. The thickness of the epidermis. Br J Dermatol 1973, 89:467-476.
2. Sandby-Møller J, Poulsen T, Wulf HC. Epidermal thickness at different body sites: relationship to age, gender, pigmentation, blood content, skin type and smoking habits. Acta Derm Venereol 2003, 83:410-413.
3. Histopathologie der Hautkrankheiten 1894, Unna., Berlin, August Hirschwald
4. Miescher G. Das Problem des Lichtschutzes und der Lichtgewöhnung. Strahlentherapie 1930, 35:403-443.
5. Gambichler T, Künzlberger B, Paech V. UVA1 and UVB irradiated skin investigated by optical coherence tomography in vivo: a preliminary study. Clin Exp Dermatol 2005, 30:79-82.
6. Bech-Thomsen N, Wulf HC. Photoprotection due to pigmentation and epidermal thickness after repeated exposure to ultraviolet light and psoralen plus ultraviolet A therapy. Photodermatol Photoimmunol Photomed 1996, 11:213-218.
7. Kambayashi H, Yamashita M, Odake Y. Epidermal changes caused by chronic low-dose UV irradiation induce wrinkle formation in hairless mouse. J Dermatol Sci 2001, 27((Suppl. 1)):S19-S25.
8. Lavker RM, Gerberick GF, Veres D, Irwin CJ, Kaidbey KH. Cumulative effects from repeated exposures to suberythemal doses of UVB and UVA in human skin. J Am Acad Dermatol 1995, 32:53-62.
9. Pearse AD, Gaskell SA, Marks R. Epidermal changes in human skin following irradiation with either UVB or UVA. J Invest Dermatol 1987, 88:83-87.
10. Corcuff P, Bertrand C, Leveque JL. Morphometry of human epidermis in vivo by real-time confocal microscopy. Arch Dermatol Res 1993, 285:475-481.
11. Huzaira M, Rius F, Rajadhyaksha M, Anderson RR, Gonzalez S. Topographic variations in normal skin, as viewed by in vivo reflectance confocal microscopy. J Invest Dermatol 2001, 116:846-852.
12. Nouveau-Richard S, Monot M, Bastien P, de Lacharrière O. In vivo epidermal thickness measurement: ultrasound vs. confocal imaging. Skin Res Technol 2004, 10:136-140.
13. Ormerod AD, Shah SAA, Copeland P, Omar G, Winfield A. Treatment of psoriasis with topical sirolimus: preclinical development and a randomized, double-blind trial. Br J Dermatol 2005, 152:758-764.
14. Cossmann M, Welzel J. Evaluation of the atrophogenic potential of different glucocorticoids using optical coherence tomography, 20-MHz ultrasound and profilometry; a double-blind, placebo-controlled trial. Br J Dermatol 2006, 155:700-706.
15. Desai TD, Desai AD, Horowitz DC, Kartono F, Wahl T. The use of high-frequency ultrasound in the evaluation of superficial and nodular basal cell carcinomas. Dermatol Surg 2007, 33:1220-1227. discussion 1226-1227
16. Gambichler T, Boms S, Stücker M. Epidermal thickness assessed by optical coherence tomography and routine histology: preliminary results of method comparison. J Eur Acad Dermatol Venereol 2006, 20:791-795.
17. Mogensen M, Morsy HA, Thrane L, Jemec GBE. Morphology and epidermal thickness of normal skin imaged by optical coherence tomography. Dermatology (Basel) 2008, 217:14-20.
18. König K, Weinigel M, Hoppert D. Multiphoton tissue imaging using high-NA microendoscopes and flexible scan heads for clinical studies and small animal research. J Biophotonics 2008, 1:506-513.
19. König K. Clinical multiphoton tomography. J Biophotonics 2008, 1:13-23.
20. Koehler MJ, König K, Elsner P, Bückle R, Kaatz M. In vivo assessment of human skin aging by multiphoton laser scanning tomography. Opt Lett 2006, 31:2879-2881.
21. Sellheyer K. Pathogenesis of solar elastosis: synthesis or degradation? J Cutan Pathol 2003, 30:123-127.
22. Koehler MJ, Hahn S, Preller A, Elsner P, Ziemer M, Bauer A, König K, Bückle R, Fluhr JW, Kaatz M. Morphological skin ageing criteria by multiphoton laser scanning tomography: non-invasive in vivo scoring of the dermal fibre network. Exp Dermatol 2008, 17:519-523.
23. Batisse D, Bazin R, Baldeweck T, Querleux B, Lévêque J. Influence of age on the wrinkling capacities of skin. Skin Res Technol 2002, 8:148-154.
24. El-Domyati M, Attia S, Saleh F. Intrinsic aging vs. photoaging: a comparative histopathological, immunohistochemical, and ultrastructural study of skin. Exp Dermatol 2002, 11:398-405.