Modeling the bifurcating flow in a CT-scanned human lung airway

Journal of Biomechanics

Volumn 41, Issue 12, 2008, Pages 2681-2688

  Luo, H Y ^a   Liu, Y ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

CT scan; Human lung; Inspiratory flow; Numerical simulation

Indexed keywords

AERODYNAMICS; BIOLOGICAL ORGANS; CHLORINE COMPOUNDS; ELECTRIC INSTRUMENT TRANSFORMERS; FLOW PATTERNS; KETONES; MIXED CONVECTION; REYNOLDS NUMBER; RHENIUM;

AIR FLOWS; AIR-BREATHING; AXIAL VELOCITY; CT SCAN; FLOW CHARACTERISTICS; FLOW-RATE; HUMAN LUNG; HUMAN LUNGS; INLET VELOCITIES; INSPIRATORY FLOW; LOW-REYNOLDS-NUMBER; NUMERICAL SIMULATION; REYNOLDS; SECONDARY VELOCITY; TURBULENT MODELS;

TURBULENCE MODELS;

ADULT; AIRFLOW; AIRWAY; ARTICLE; BREATHING; BRONCHUS; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; FLOW RATE; HUMAN; INSPIRATORY CAPACITY; LARYNX; LUNG LOBE; LUNG MODEL; MALE; MATHEMATICAL MODEL; PRIORITY JOURNAL; SIMULATION; TRACHEA;

BRONCHI; BRONCHOGRAPHY; COMPUTER SIMULATION; HUMANS; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; PULMONARY VENTILATION; RESPIRATORY MECHANICS; RHEOLOGY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 49449087914     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2008.06.018     Document Type: Article

References (24)

1. Balashazy I., and Hofmann W. Deposition of aerosols in asymmetric airway bifurcations. Journal of Aerosol Science 26 (1995) 273-292
2. Balashazy I., Hofmann W., and Martonen T.B. Inspiratory particle deposition in airway bifurcation models. Journal of Aerosol Science 22 (1991) 15-30
3. Beachey W. Respiratory Care Anatomy and Physiology (1998), Mosby, St Louis
4. Comer J.K., Kleinstreuer C., and Zhang Z. Flow structures and particle deposition patterns in double-bifurcation airway models. Part 1. Air flow fields. Journal of Fluid Mechanics 435 (2001) 25-54
5. Ertbruggen C.V., Hirsch C., and Paiva M. Anatomically based three-dimensional model of airways to simulate flow and particle transport using computational fluid dynamics. Journal of Applied Physiology 98 (2005) 970-980
6. Farkas A., and Balashazy I. Simulation of the effect of local obstructions and blockage on airflow and aerosol deposition in central human airways. Journal of Aerosol Science 38 (2007) 865-884
7. Isabey D., and Chang H.K. Steady and unsteady pressure-flow relationships in central airways. Journal of Applied Physiology 51 (1981) 1338-1348
8. Kim C.S., and Iglesias A.J. Deposition of inhaled particles in bifurcating airway models: I. Inspiratory deposition. Journal of Aerosol Medicine 2 (1989) 1-14
9. Kim C.S., Iglesias A.J., and Garcia L. Deposition of inhaled particles in bifurcating airway models: II. Expiratory deposition. Journal of Aerosol Medicine 2 (1989) 15-27
10. Li Z., Kleinstreuer C., and Zhang Z. Simulation of airflow fields and microparticle deposition in realistic human lung airway models. Part I: Airflow patterns. European Journal of Mechanics B/Fluids 26 (2007) 650-668
11. Lin C.L., Tawhai M.H., McLennan G., and Hoffman E.A. Characteristics of the turbulent laryngeal jet and its effect on airflow in the human intra-thoracic airways. Respiratory Physiology and Neurobiology 157 (2007) 295-309
12. Liu Y., So R.M.C., and Zhang C.H. Modeling the bifurcating flow in a human lung airway. Journal of Biomechanics 35 (2002) 477-485
13. Liu Y., So R.M.C., and Zhang C.H. Modeling the bifurcating flow in an asymmetric human lung airway. Journal of Biomechanics 36 (2003) 951-959
14. Luo H.Y., Liu Y., and Yang X.L. Particle deposition in obstructed airways. Journal of Biomechanics 40 (2007) 3096-3104
15. Pedley T.J. Pulmonary fluid dynamics. Annual Review of Fluid Mechanics 9 (1977) 229-274
16. 3He magnetic resonance phase-contrast velocimetry. Journal of Applied Physiology 102 (2007) 2012-2023
17. Schroter R.C., and Sudlow M.F. Flow patterns in models of the human bronchial airways. Respiratory Physiology 7 (1969) 341-355
18. Snyder B., and Olson D.E. Flow development in a model airway bronchus. Journal of Fluid Mechanics 207 (1989) 378-392
19. Weibel E.R. Morphometry of the Human Lung (1963), Springer, Academic Press, New York
20. Yang X.L., Liu Y., and Luo H.Y. Respiratory flow in obstructed airways. Journal of Biomechanics 39 (2006) 2743-2751
21. Zhang Z., and Kleinstreuer C. Low-Reynolds-Number turbulent flows in locally constricted conduits: a comparison study. AIAA Journal 41 (2003) 831-837
22. Zhang Z., and Kleinstreuer C. Airflow structures and nano-particle deposition in a human upper airway model. Journal of Computational Physics 198 (2004) 178-210
23. Zhang Z., Kleinstreuer C., and Kim C.S. Flow structure and particle transport in a triple bifurcation airway model. ASME Journal of Fluids Engineering 123 (2001) 320-330
24. Zhao Y., and Lieber B.B. Steady inspiratory flow in a model symmetric bifurcation. ASME Journal of Biomechanical Engineering 116 (1994) 488-496