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Volumn 12, Issue 3, 2010, Pages 430-437

The effect of increased inspired fraction of oxygen on brain tissue oxygen tension in children with severe traumatic brain injury

Author keywords

Arterial oxygen tension; Brain tissue oxygen tension; Children; Outcome; Traumatic brain injury

Indexed keywords

OXYGEN;

EID: 77955094062     PISSN: 15416933     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12028-010-9344-3     Document Type: Article
Times cited : (52)

References (50)
  • 1
    • 32044450073 scopus 로고    scopus 로고
    • Reduced mortality rate in patients with severe traumatic brain injury treated with brain tissue oxygen monitoring
    • Stiefel MF, Spiotta A, Gracias VH, et al. Reduced mortality rate in patients with severe traumatic brain injury treated with brain tissue oxygen monitoring. J Neurosurg. 2005;103:805-811
    • (2005) J Neurosurg , vol.103 , pp. 805-811
    • Stiefel, M.F.1    Spiotta, A.2    Gracias, V.H.3
  • 4
    • 69949136596 scopus 로고    scopus 로고
    • Brain tissue oxygen tension monitoring in pediatric severe traumatic brain injury: Part 1: Relationship with outcome
    • Figaji AA, Zwane E, Thompson C, et al. Brain tissue oxygen tension monitoring in pediatric severe traumatic brain injury: Part 1: Relationship with outcome. Childs Nerv Syst. 2009;25(10): 1325-1333
    • (2009) Childs Nerv Syst , vol.25 , Issue.10 , pp. 1325-1333
    • Figaji, A.A.1    Zwane, E.2    Thompson, C.3
  • 6
    • 56649084462 scopus 로고    scopus 로고
    • Does adherence to treatment targets in children with severe traumatic brain injury avoid brain hypoxia? A brain tissue oxygenation study
    • discussion 91-92
    • Figaji AA, Fieggen AG, Argent AC, Leroux PD, Peter JC. Does adherence to treatment targets in children with severe traumatic brain injury avoid brain hypoxia? A brain tissue oxygenation study. Neurosurgery. 2008;63:83-91, discussion 91-92.
    • (2008) Neurosurgery , vol.63 , pp. 83-91
    • Figaji, A.A.1    Fieggen, A.G.2    Argent, A.C.3    Leroux, P.D.4    Peter, J.C.5
  • 7
    • 69949144763 scopus 로고    scopus 로고
    • Brain tissue oxygen tension monitoring in pediatric severe traumatic brain injury: Part 2: Relationship with clinical, physiological, and treatment factors
    • Figaji AA, Zwane E, Thompson C, et al. Brain tissue oxygen tension monitoring in pediatric severe traumatic brain injury: Part 2: Relationship with clinical, physiological, and treatment factors. Childs Nerv Syst. 2009;25(10):1335-1343
    • (2009) Childs Nerv Syst , vol.25 , Issue.10 , pp. 1335-1343
    • Figaji, A.A.1    Zwane, E.2    Thompson, C.3
  • 8
    • 45149106869 scopus 로고    scopus 로고
    • Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury
    • Rosenthal G, Hemphill JC III, Sorani M, et al. Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury. Crit Care Med. 2008;36:1917-1924
    • (2008) Crit Care Med , vol.36 , pp. 1917-1924
    • Rosenthal, G.1    Hemphill III, J.C.2    Sorani, M.3
  • 9
    • 0032101792 scopus 로고    scopus 로고
    • Correlations between brain tissue oxygen tension, carbon dioxide tension, pH, and cerebral blood flow-a better way of monitoring the severely injured brain?
    • Doppenberg EM, Zauner A, Bullock R, Ward JD, Fatouros PP, YoungHF. Correlations between brain tissue oxygen tension, carbon dioxide tension, pH, and cerebral blood flow-a better way of monitoring the severely injured brain? Surg Neurol. 1998;49: 650-654
    • (1998) Surg Neurol , vol.49 , pp. 650-654
    • Doppenberg, E.M.1    Zauner, A.2    Bullock, R.3    Ward, J.D.4    Fatouros P.P.Young, H.F.5
  • 11
    • 12444261736 scopus 로고    scopus 로고
    • Correlation of continuously monitored regional cerebral blood flow and brain tissue oxygen
    • discussion 56
    • Jaeger M, Soehle M, Schuhmann MU, Winkler D, Meixensberger J. Correlation of continuously monitored regional cerebral blood flow and brain tissue oxygen. Acta Neurochir (Wien). 2005;147: 51-56, discussion 56.
    • (2005) Acta Neurochir (Wien) , vol.147 , pp. 51-56
    • Jaeger, M.1    Soehle, M.2    Schuhmann, M.U.3    Winkler, D.4    Meixensberger, J.5
  • 13
    • 0028885522 scopus 로고
    • 2 pH and temperature monitoring: Evaluation in the feline brain
    • discussion 1176-1177
    • Zauner A, Bullock R, Di X, Young HF. Brain oxygen, CO2, pH, and temperature monitoring: evaluation in the feline brain. Neurosurgery. 1995;37:1168-76, discussion 1176-1177.
    • (1995) Neurosurgery , vol.37 , pp. 1168-1176
    • Zauner, A.1    Bullock, R.2    Di, X.3    Young, H.F.4
  • 14
    • 29344443755 scopus 로고    scopus 로고
    • Relationship between brain tissue oxygen tension and CT perfusion: Feasibility and initial results
    • Hemphill JC III, Smith WS, Sonne DC, Morabito D, Manley GT. Relationship between brain tissue oxygen tension and CT perfusion: feasibility and initial results. AJNR Am J Neuroradiol. 2005;26:1095-1100
    • (2005) AJNR Am J Neuroradiol , vol.26 , pp. 1095-1100
    • Hemphill III, J.C.1    Smith, W.S.2    Sonne, D.C.3    Morabito, D.4    Manley, G.T.5
  • 15
    • 0036121840 scopus 로고    scopus 로고
    • Measurement of brain tissue oxygenation performed using positron emission tomography scanning to validate a novel monitoring method
    • Gupta AK, Hutchinson PJ, Fryer T, et al. Measurement of brain tissue oxygenation performed using positron emission tomography scanning to validate a novel monitoring method. J Neurosurg. 2002;96:263-268
    • (2002) J Neurosurg , vol.96 , pp. 263-268
    • Gupta, A.K.1    Hutchinson, P.J.2    Fryer, T.3
  • 16
    • 3042823809 scopus 로고    scopus 로고
    • Individual value of brain tissue oxygen pressure, microvascular oxygen saturation, cytochrome redox level, and energy metabolites in detecting critically reduced cerebral energy state during acute changes in global cerebral perfusion
    • Scheufler KM, Lehnert A, Rohrborn HJ, Nadstawek J, Thees C. Individual value of brain tissue oxygen pressure, microvascular oxygen saturation, cytochrome redox level, and energy metabolites in detecting critically reduced cerebral energy state during acute changes in global cerebral perfusion. J Neurosurg Anesthesiol. 2004;16:210-219
    • (2004) J Neurosurg Anesthesiol , vol.16 , pp. 210-219
    • Scheufler, K.M.1    Lehnert, A.2    Rohrborn, H.J.3    Nadstawek, J.4    Thees, C.5
  • 17
    • 0344837722 scopus 로고    scopus 로고
    • Lack of improvement in cerebral metabolism after hyperoxia in severe head injury: A microdialysis study
    • Magnoni S, Ghisoni L, Locatelli M, et al. Lack of improvement in cerebral metabolism after hyperoxia in severe head injury: a microdialysis study. J Neurosurg. 2003;98:952-958
    • (2003) J Neurosurg , vol.98 , pp. 952-958
    • Magnoni, S.1    Ghisoni, L.2    Locatelli, M.3
  • 18
    • 4143109120 scopus 로고    scopus 로고
    • Normobaric hyperoxia-induced improvement in cerebral metabolism and reduction in intracranial pressure in patients with severe head injury: A prospective historical cohort-matched study
    • Tolias CM, Reinert M, Seiler R, Gilman C, Scharf A, Bullock MR. Normobaric hyperoxia-induced improvement in cerebral metabolism and reduction in intracranial pressure in patients with severe head injury: a prospective historical cohort-matched study. J Neurosurg. 2004;101:435-444
    • (2004) J Neurosurg , vol.101 , pp. 435-444
    • Tolias, C.M.1    Reinert, M.2    Seiler, R.3    Gilman, C.4    Scharf, A.5    Bullock, M.R.6
  • 19
    • 37549043528 scopus 로고    scopus 로고
    • Effect of hyperoxia on regional oxygenation and metabolism after severe traumatic brain injury: Preliminary findings
    • Nortje J, Coles JP, Timofeev I, et al. Effect of hyperoxia on regional oxygenation and metabolism after severe traumatic brain injury: Preliminary findings. Crit Care Med. 2008;36:273-281
    • (2008) Crit Care Med , vol.36 , pp. 273-281
    • Nortje, J.1    Coles, J.P.2    Timofeev, I.3
  • 20
    • 34047239890 scopus 로고    scopus 로고
    • Effect of hyperoxia on cerebral metabolic rate for oxygen measured using positron emission tomography in patients with acute severe head injury
    • Diringer MN, Aiyagari V, Zazulia AR, Videen TO, Powers WJ. Effect of hyperoxia on cerebral metabolic rate for oxygen measured using positron emission tomography in patients with acute severe head injury. J Neurosurg. 2007;106:526-529
    • (2007) J Neurosurg , vol.106 , pp. 526-529
    • Diringer, M.N.1    Aiyagari, V.2    Zazulia, A.R.3    Videen, T.O.4    Powers, W.J.5
  • 21
    • 1342347864 scopus 로고    scopus 로고
    • Alveolar cell death in hyperoxia-induced lung injury
    • Pagano A, Barazzone-Argiroffo C. Alveolar cell death in hyperoxia-induced lung injury. Ann N Y Acad Sci. 2003;1010: 405-416
    • (2003) Ann N Y Acad Sci , vol.1010 , pp. 405-416
    • Pagano, A.1    Barazzone-Argiroffo, C.2
  • 22
    • 0015069633 scopus 로고
    • Pulmonary oxygen toxicity: A review
    • Clark JM, Lambertsen CJ. Pulmonary oxygen toxicity: a review. Pharmacol Rev. 1971;23:37-133.
    • (1971) Pharmacol Rev , vol.23 , pp. 37-133
    • Clark, J.M.1    Lambertsen, C.J.2
  • 23
    • 0020597168 scopus 로고
    • Cerebral vasomotor responsiveness during 100% oxygen inhalation in cerebral ischemia
    • Nakajima S, Meyer JS, Amano T, Shaw T, Okabe T, Mortel KF. Cerebral vasomotor responsiveness during 100% oxygen inhalation in cerebral ischemia. Arch Neurol. 1983;40:271-276 (Pubitemid 13083550)
    • (1983) Archives of Neurology , vol.40 , Issue.5 , pp. 271-276
    • Nakajima, S.1    Meyer, J.S.2    Amano, T.3
  • 24
    • 0344413700 scopus 로고    scopus 로고
    • Independent cerebral vasoconstrictive effects of hyperoxia and accompanying arterial hypocapnia at 1 ATA
    • Floyd TF, Clark JM, Gelfand R, et al. Independent cerebral vasoconstrictive effects of hyperoxia and accompanying arterial hypocapnia at 1 ATA. J Appl Physiol. 2003;95:2453-2461
    • (2003) J Appl Physiol , vol.95 , pp. 2453-2461
    • Floyd, T.F.1    Clark, J.M.2    Gelfand, R.3
  • 25
    • 84893186401 scopus 로고    scopus 로고
    • Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 17. Critical pathway for the treatment of established intracranial hypertension in pediatric traumatic brain injury
    • Adelson PD, Bratton SL, Carney NA, et al. Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 17. Critical pathway for the treatment of established intracranial hypertension in pediatric traumatic brain injury. Pediatr Crit Care Med. 2003;4: S65-7.
    • (2003) Pediatr Crit Care Med , vol.4
    • Adelson, P.D.1    Bratton, S.L.2    Carney, N.A.3
  • 26
    • 84893180076 scopus 로고    scopus 로고
    • Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 6. Threshold for treatment of intracranial hypertension
    • Adelson PD, Bratton SL, Carney NA, et al. Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 6. Threshold for treatment of intracranial hypertension. Pediatr Crit Care Med. 2003; 4:S25-7.
    • (2003) Pediatr Crit Care Med , vol.4
    • Adelson, P.D.1    Bratton, S.L.2    Carney, N.A.3
  • 27
    • 0141642132 scopus 로고    scopus 로고
    • Assessment of cerebrovascular autoregulation in head-injured patients: A validation study
    • Steiner LA, Coles JP, Johnston AJ, et al. Assessment of cerebrovascular autoregulation in head-injured patients: a validation study. Stroke. 2003;34:2404-2409
    • (2003) Stroke , vol.34 , pp. 2404-2409
    • Steiner, L.A.1    Coles, J.P.2    Johnston, A.J.3
  • 28
    • 0022449467 scopus 로고
    • Transcranial Doppler measurement of middle cerebral artery blood flow velocity: A validation study
    • Bishop CC, Powell S, Rutt D, Browse NL. Transcranial Doppler measurement of middle cerebral artery blood flow velocity: a validation study. Stroke. 1986;17:913-915
    • (1986) Stroke , vol.17 , pp. 913-915
    • Bishop, C.C.1    Powell, S.2    Rutt, D.3    Browse, N.L.4
  • 29
    • 38149072217 scopus 로고    scopus 로고
    • The role of lung function in brain tissue oxygenation following traumatic brain injury
    • Rosenthal G, Hemphill JC, Sorani M, et al. The role of lung function in brain tissue oxygenation following traumatic brain injury. J Neurosurg. 2008;108:59-65.
    • (2008) J Neurosurg , vol.108 , pp. 59-65
    • Rosenthal, G.1    Hemphill, J.C.2    Sorani, M.3
  • 30
    • 2942565793 scopus 로고    scopus 로고
    • Diffusion limited oxygen delivery following head injury
    • Menon DK, Coles JP, Gupta AK, et al. Diffusion limited oxygen delivery following head injury. Crit Care Med. 2004;32:1384-1390
    • (2004) Crit Care Med , vol.32 , pp. 1384-1390
    • Menon, D.K.1    Coles, J.P.2    Gupta, A.K.3
  • 31
    • 0037405083 scopus 로고    scopus 로고
    • Hyperoxia: Good or bad?
    • discussion 944
    • Bullock MR. Hyperoxia: good or bad? J Neurosurg. 2003;98: 943-944, discussion 944.
    • (2003) J Neurosurg , vol.98 , pp. 943-944
    • Bullock, M.R.1
  • 32
    • 38149113378 scopus 로고    scopus 로고
    • Brain tissue oxygen tension response to induced hyperoxia reduced in hypoperfused brain
    • Hlatky R, Valadka AB, Gopinath SP, Robertson CS. Brain tissue oxygen tension response to induced hyperoxia reduced in hypoperfused brain. J Neurosurg. 2008;108:53-58
    • (2008) J Neurosurg , vol.108 , pp. 53-58
    • Hlatky, R.1    Valadka, A.B.2    Gopinath, S.P.3    Robertson, C.S.4
  • 34
    • 36749077498 scopus 로고    scopus 로고
    • Oxygen administration, cerebral blood flow velocity, and dynamic cerebral autoregulation
    • Nishimura N, Iwasaki K, Ogawa Y, Shibata S. Oxygen administration, cerebral blood flow velocity, and dynamic cerebral autoregulation. Aviat Space Environ Med. 2007;78:1121-1127
    • (2007) Aviat Space Environ Med , vol.78 , pp. 1121-1127
    • Nishimura, N.1    Iwasaki, K.2    Ogawa, Y.3    Shibata, S.4
  • 35
    • 34250862014 scopus 로고    scopus 로고
    • Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits periinfarct depolarizations in experimental focal ischaemia
    • Shin HK, Dunn AK, Jones PB, et al. Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits periinfarct depolarizations in experimental focal ischaemia. Brain. 2007;130:1631-1642
    • (2007) Brain , vol.130 , pp. 1631-1642
    • Shin, H.K.1    Dunn, A.K.2    Jones, P.B.3
  • 37
    • 0033053241 scopus 로고    scopus 로고
    • Measuring brain tissue oxygenation compared with jugular venous oxygen saturation for monitoring cerebral oxygenation after traumatic brain injury
    • Gupta AK, Hutchinson PJ, Al-Rawi P, et al. Measuring brain tissue oxygenation compared with jugular venous oxygen saturation for monitoring cerebral oxygenation after traumatic brain injury. Anesth Analg. 1999;88:549-553
    • (1999) Anesth Analg , vol.88 , pp. 549-553
    • Gupta, A.K.1    Hutchinson, P.J.2    Al-Rawi, P.3
  • 39
    • 66449125373 scopus 로고    scopus 로고
    • Brain tissue oxygen and outcome after severe traumatic brain injury: a systematic review
    • Maloney-Wilensky E, Gracias V, Itkin A, et al. Brain tissue oxygen and outcome after severe traumatic brain injury: a systematic review. Crit Care Med. 2009;37:2057-2063
    • (2009) Crit Care Med , vol.37 , pp. 2057-2063
    • Maloney-Wilensky, E.1    Gracias, V.2    Itkin, A.3
  • 40
    • 49949096866 scopus 로고    scopus 로고
    • The impact of development of acute lung injury on hospital mortality in critically ill trauma patients
    • Shah CV, Localio AR, Lanken PN, et al. The impact of development of acute lung injury on hospital mortality in critically ill trauma patients. Crit Care Med. 2008;36:2309-2315
    • (2008) Crit Care Med , vol.36 , pp. 2309-2315
    • Shah, C.V.1    Localio, A.R.2    Lanken, P.N.3
  • 41
    • 0031968901 scopus 로고    scopus 로고
    • Increased free radical production due to subdural hematoma in the rat: Effect of increased inspired oxygen fraction
    • Doppenberg EM, Rice MR, Di X, Young HF, Woodward JJ, Bullock R. Increased free radical production due to subdural hematoma in the rat: effect of increased inspired oxygen fraction. J Neurotrauma. 1998;15:337-347
    • (1998) J Neurotrauma , vol.15 , pp. 337-347
    • Doppenberg, E.M.1    Rice, M.R.2    Di, X.3    Young, H.F.4    Woodward, J.J.5    Bullock, R.6
  • 42
    • 68349104085 scopus 로고    scopus 로고
    • Effect of short periods of normobaric hyperoxia on local brain tissue oxygenation and cerebrospinal fluid oxidative stress markers in severe traumatic brain injury
    • doi:10.1089/neu.2008-0624
    • Puccio AM, Hoffman LA, Bayir H, et al. Effect of short periods of normobaric hyperoxia on local brain tissue oxygenation and cerebrospinal fluid oxidative stress markers in severe traumatic brain injury. J Neurotrauma. 2009. doi:10.1089/neu.2008-0624.
    • (2009) J Neurotrauma
    • Puccio, A.M.1    Hoffman, L.A.2    Bayir, H.3
  • 43
    • 0037757623 scopus 로고    scopus 로고
    • Effects of cerebral perfusion pressure and increased fraction of inspired oxygen on brain tissue oxygen, lactate and glucose in patients with severe head injury
    • discussion 349-350
    • Reinert M, Barth A, Rothen HU, Schaller B, Takala J, Seiler RW. Effects of cerebral perfusion pressure and increased fraction of inspired oxygen on brain tissue oxygen, lactate and glucose in patients with severe head injury. Acta Neurochir (Wien). 2003;145:341-9. discussion 349-350.
    • (2003) Acta Neurochir (Wien) , vol.145 , pp. 341-349
    • Reinert, M.1    Barth, A.2    Rothen, H.U.3    Schaller, B.4    Takala, J.5    Seiler, R.W.6
  • 44
    • 3242758983 scopus 로고    scopus 로고
    • Influence of oxygen therapy on glucose-lactate metabolism after diffuse brain injury
    • Reinert M, Schaller B, Widmer HR, Seiler R, Bullock R. Influence of oxygen therapy on glucose-lactate metabolism after diffuse brain injury. J Neurosurg. 2004;101:323-329
    • (2004) J Neurosurg , vol.101 , pp. 323-329
    • Reinert, M.1    Schaller, B.2    Widmer, H.R.3    Seiler, R.4    Bullock, R.5
  • 45
    • 33746972929 scopus 로고    scopus 로고
    • Electron paramagnetic resonance-guided normobaric hyperoxia treatment protects the brain by maintaining penumbral oxygenation in a rat model of transient focal cerebral ischemia
    • Liu S, Liu W, Ding W, Miyake M, Rosenberg GA, Liu KJ. Electron paramagnetic resonance-guided normobaric hyperoxia treatment protects the brain by maintaining penumbral oxygenation in a rat model of transient focal cerebral ischemia. J Cereb Blood Flow Metab. 2006;26:1274-1284
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 1274-1284
    • Liu, S.1    Liu, W.2    Ding, W.3    Miyake, M.4    Rosenberg, G.A.5    Liu, K.J.6
  • 46
    • 33745684624 scopus 로고    scopus 로고
    • Normoxic resuscitation after cardiac arrest protects against hippocampal oxidative stress, metabolic dysfunction, and neuronal death
    • Vereczki V, Martin E, Rosenthal RE, Hof PR, Hoffman GE, Fiskum G. Normoxic resuscitation after cardiac arrest protects against hippocampal oxidative stress, metabolic dysfunction, and neuronal death. J Cereb Blood Flow Metab. 2006;26:821-835
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 821-835
    • Vereczki, V.1    Martin, E.2    Rosenthal, R.E.3    Hof, P.R.4    Hoffman, G.E.5    Fiskum, G.6
  • 47
    • 0035115403 scopus 로고    scopus 로고
    • Brain oxygen tension, oxygen supply, and oxygen consumption during arterial hyperoxia in a model of progressive cerebral ischemia
    • Rossi S, Stocchetti N, Longhi L, et al. Brain oxygen tension, oxygen supply, and oxygen consumption during arterial hyperoxia in a model of progressive cerebral ischemia. J Neurotrauma. 2001;18:163-174
    • (2001) J Neurotrauma , vol.18 , pp. 163-174
    • Rossi, S.1    Stocchetti, N.2    Longhi, L.3
  • 48
    • 0036784843 scopus 로고    scopus 로고
    • Does tissue oxygentension reliably reflect cerebral oxygen delivery and consumption?
    • Scheufler KM, Rohrborn HJ, Zentner J. Does tissue oxygentension reliably reflect cerebral oxygen delivery and consumption? Anesth Analg. 2002;95:1042-1048
    • (2002) Anesth Analg , vol.95 , pp. 1042-1048
    • Scheufler, K.M.1    Rohrborn, H.J.2    Zentner, J.3
  • 49
    • 3042657048 scopus 로고    scopus 로고
    • The influence of allogeneic red blood cell transfusion compared with 100% oxygen ventilation on systemic oxygen transport and skeletal muscle oxygen tension after cardiac surgery
    • Suttner S, Piper SN, Kumle B, et al. The influence of allogeneic red blood cell transfusion compared with 100% oxygen ventilation on systemic oxygen transport and skeletal muscle oxygen tension after cardiac surgery. Anesth Analg. 2004;99:2-11.
    • (2004) Anesth Analg , vol.99 , pp. 2-11
    • Suttner, S.1    Piper, S.N.2    Kumle, B.3
  • 50
    • 6844242308 scopus 로고    scopus 로고
    • Effects of hyperoxic ventilation on hemodilution-induced changes in anesthetized dogs
    • Habler OP, Kleen MS, Hutter JW, et al. Effects of hyperoxic ventilation on hemodilution-induced changes in anesthetized dogs. Transfusion. 1998;38:135-144
    • (1998) Transfusion , vol.38 , pp. 135-144
    • Habler, O.P.1    Kleen, M.S.2    Hutter, J.W.3


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