Autophagy of intracellular microbes and mitochondria: Two sides of the same coin?

F1000 Biology Reports

Volumn 2, Issue 1, 2010, Pages

  Deretic, Vojo ^a  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; AUTOPHAGY; CELL SURVIVAL; EUKARYOTE; IMMUNITY; INTRACELLULAR BACTERIUM; MITOCHONDRION; NONHUMAN; REVIEW;

EUKARYOTA;

EID: 77955077765     PISSN: 17404118     EISSN: 1757594X     Source Type: Journal    
DOI: 10.3410/B2-45     Document Type: Review

References (18)

1. Mizushima N, Levine B, Cuervo AM, Klionsky DJ: Autophagy fights disease through cellular self-digestion. Nature 2008, 451:1069-75. (Pubitemid 351317450)
2. Deretic V, Levine B: Autophagy, immunity, and microbial adaptations. Cell Host Microbe 2009, 5:527-49.
3. Mizushima N, Yoshimori T, Levine B: Methods in mammalian autophagy research. Cell 2010, 140:313-26.
4. Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI, Deretic V: Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 2004, 119:753-66.
5. Nakagawa I, Amano A, Mizushima N, Yamamoto A, Yamaguchi H, Kamimoto T, Nara A, Funao J, Nakata M, Tsuda K, Hamada S, Yoshimori T: Autophagy defends cells against invading group A Streptococcus. Science 2004, 306:1037-40.
6. Nedjic J, Aichinger M, Emmerich J, Mizushima N, Klein L: Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance. Nature 2008, 455:396-400.
7. Jagannath C, Lindsey DR, Dhandayuthapani S, Xu Y, Hunter RL Jr, Eissa NT: Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells. Nat Med 2009, 15:267-76.
8. English L, Chemali M, Duron J, Rondeau C, Laplante A, Gingras D, Alexander D, Leib D, Norbury C, Lippé R, Desjardins M: Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. Nat Immunol 2009, 10:480-7.
9. Sandoval H, Thiagarajan P, Dasgupta SK, Schumacher A, Prchal JT, Chen M, Wang J: Essential role for Nix in autophagic maturation of erythroid cells. Nature 2008, 454:232-5.
10. Pua HH, Guo J, Komatsu M, He YW: Autophagy is essential for mitochondrial clearance in mature T lymphocytes. J Immunol 2009, 182:4046-55.
11. Geisler S, Holmstrom KM, Skujat D, Fiesel FC, Rothfuss OC, Kahle PJ, Springer W: PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol 2010, 12:119-31.
12. Kirkin V, Lamark T, Sou YS, Bjørkøy G, Nunn JL, Bruun JA, Shvets E, McEwan DG, Clausen TH, Wild P, Bilusic I, Theurillat JP, Øvervatn A, Ishii T, Elazar Z, Komatsu M, Dikic I, Johansen T: A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Mol Cell 2009, 33:505-16.
13. Orvedahl A, Macpherson S, Sumpter R Jr, Talloczy Z, Zou Z, Levine B: Autophagy protects against Sindbis virus infection of the central nervous system. Cell Host Microbe 2010, 7:115-27.
14. Yoshikawa Y, Ogawa M, Hain T, Yoshida M, Fukumatsu M, Kim M, Mimuro H, Nakagawa I, Yanagawa T, Ishii T, Kakizuka A, Sztul E, Chakraborty T, Sasakawa C: Listeria monocytogenes ActA-mediated escape from autophagic recognition. Nat Cell Biol 2009, 11:1233-40. Evaluated by 6.0 Must Read Evaluated by Pascale Cossart 28 Oct 2009
15. Dupont N, Lacas-Gervais S, Bertout J, Paz I, Freche B, Van Nhieu GT, van der Goot FG, Sansonetti PJ, Lafont F: Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy. Cell Host Microbe 2009, 6:137-49.
16. Zheng YT, Shahnazari S, Brech A, Lamark T, Johansen T, Brumell JH: The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway. J Immunol 2009, 183:5909-16.
17. Thurston TL, Ryzhakov G, Bloor S, von Muhlinen N, Randow F: The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria. Nat Immunol 2009, 10:1215-21.
18. Ponpuak M, Davis AS, Roberts EA, Delgado MA, Dinkins C, Zhao Z, Virgin HW 4th, Kyei GB, Johansen T, Vergne I, Deretic V: Delivery of cytosolic components by autophagic adapter portein p62 endows autophagosomes with unique antimicrobial properties. Immunity 2010, 32:329-41.