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Volumn 30, Issue 6, 2010, Pages 2087-2092

Clioquinol independently targets NF-κB and lysosome pathways in human cancer cells

Author keywords

Cancer; Clioquinol; DU 145; Lysosome; NF B

Indexed keywords

AMMONIA; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CLIOQUINOL; DNA; TRANSCRIPTION FACTOR RELA; ZINC CHLORIDE;

EID: 77955074869     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (30)

References (20)
  • 4
    • 14844293088 scopus 로고    scopus 로고
    • Anticancer metal compounds in NCI's tumor-screening database: Putative mode of action
    • DOI 10.1016/j.bcp.2005.01.001
    • Huang R, Wallqvist A and Covell DG: Anticancer metal compounds in NCI's tumor-screening database: putative mode of action. Biochem Pharmacol 69: 1009-1039, 2005. (Pubitemid 40349015)
    • (2005) Biochemical Pharmacology , vol.69 , Issue.7 , pp. 1009-1039
    • Huang, R.1    Wallqvist, A.2    Covell, D.G.3
  • 7
    • 33847746963 scopus 로고    scopus 로고
    • Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts
    • Chen D, Cui QC, Yang H, Barrea RA, Sarkar FH, Sheng S, Yan B, Reddy GP and Dou QP: Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts. Cancer Res 67: 1636-1644, 2007.
    • (2007) Cancer Res , vol.67 , pp. 1636-1644
    • Chen, D.1    Cui, Q.C.2    Yang, H.3    Barrea, R.A.4    Sarkar, F.H.5    Sheng, S.6    Yan, B.7    Reddy, G.P.8    Dou, Q.P.9
  • 8
    • 58249091525 scopus 로고    scopus 로고
    • Clioquinol targets zinc to lysosomes in human cancer cells
    • Yu H, Zhou Y, Lind SE and Ding WQ: Clioquinol targets zinc to lysosomes in human cancer cells. Biochem J 417: 133-139, 2009.
    • (2009) Biochem J , vol.417 , pp. 133-139
    • Yu, H.1    Zhou, Y.2    Lind, S.E.3    Ding, W.Q.4
  • 9
    • 41549133200 scopus 로고    scopus 로고
    • Proteasome inhibitors in cancer therapy: Lessons from the first decade
    • Orlowski RZ and Kuhn DJ: Proteasome inhibitors in cancer therapy: lessons from the first decade. Clin Cancer Res 14: 1649-1657, 2008.
    • (2008) Clin Cancer Res , vol.14 , pp. 1649-1657
    • Orlowski, R.Z.1    Kuhn, D.J.2
  • 11
    • 2442464889 scopus 로고    scopus 로고
    • Apoptosis defects and chemotherapy resistance: Molecular interaction maps and networks
    • Pommier Y, Sordet O, Antony S, Hayward RL and Kohn KW: Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks. Oncogene 23: 2934-2949, 2004.
    • (2004) Oncogene , vol.23 , pp. 2934-2949
    • Pommier, Y.1    Sordet, O.2    Antony, S.3    Hayward, R.L.4    Kohn, K.W.5
  • 12
    • 0029858387 scopus 로고    scopus 로고
    • TNF- And cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
    • Wang CY, Mayo MW and Baldwin AS Jr: TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science 274: 784-787, 1996.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin Jr., A.S.3
  • 13
    • 0032728949 scopus 로고    scopus 로고
    • Mechanism of apoptosis induced by a lysosomotropic agent, L-leucyl-L-leucine methyl ester
    • Uchimoto T, Nohara H, Kamehara R, Iwamura M, Watanabe N and Kobayashi Y: Mechanism of apoptosis induced by a lysosomotropic agent, L-leucyl-L-leucine methyl ester. Apoptosis 4: 357-362, 1999.
    • (1999) Apoptosis , vol.4 , pp. 357-362
    • Uchimoto, T.1    Nohara, H.2    Kamehara, R.3    Iwamura, M.4    Watanabe, N.5    Kobayashi, Y.6
  • 14
    • 0027252876 scopus 로고
    • Acridine orange-mediated photodamage to cultured cells
    • Zdolsek JM: Acridine orange-mediated photodamage to cultured cells. APMIS 101: 127-32, 1993.
    • (1993) APMIS , vol.101 , pp. 127-132
    • Zdolsek, J.M.1
  • 15
    • 33748302272 scopus 로고    scopus 로고
    • Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells
    • Ding WQ, Liu B, Vaught JL, Palmiter RD and Lind SE: Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells. Mol Cancer Ther 5: 1864-1872, 2006.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1864-1872
    • Ding, W.Q.1    Liu, B.2    Vaught, J.L.3    Palmiter, R.D.4    Lind, S.E.5
  • 16
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • Karin M: Nuclear factor-kappaB in cancer development and progression. Nature 441: 431-436, 2006.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 17
    • 3242808193 scopus 로고    scopus 로고
    • Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity
    • DOI 10.1093/toxsci/kfh121
    • Thibodeau MS, Giardina C, Knecht DA, Helble J and Hubbard AK: Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity. Toxicol Sci 80: 34-48, 2004. (Pubitemid 38967394)
    • (2004) Toxicological Sciences , vol.80 , Issue.1 , pp. 34-48
    • Thibodeau, M.S.1    Giardina, C.2    Knecht, D.A.3    Helble, J.4    Hubbard, A.K.5
  • 18
    • 0032189348 scopus 로고    scopus 로고
    • Proteasome inhibitors: Valuable new tools for cell biologists
    • Lee DH and Goldberg AL: Proteasome inhibitors: valuable new tools for cell biologists. Trends Cell Biol 8: 397-403, 1998.
    • (1998) Trends Cell Biol , vol.8 , pp. 397-403
    • Lee, D.H.1    Goldberg, A.L.2
  • 19
    • 38949096081 scopus 로고    scopus 로고
    • Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome
    • Ding WX and Yin XM: Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome. Autophagy 4: 141-50, 2008.
    • (2008) Autophagy , vol.4 , pp. 141-150
    • Ding, W.X.1    Yin, X.M.2
  • 20
    • 12844255134 scopus 로고    scopus 로고
    • Overcoming limitations of natural anticancer drugs by combining with artificial agents
    • DOI 10.1016/j.tips.2004.12.002, PII S0165614704003165
    • Blagosklonny MV: Overcoming limitations of natural anticancer drugs by combining with artificial agents. Trends Pharmacol Sci 26:77-81, 2005. (Pubitemid 40170169)
    • (2005) Trends in Pharmacological Sciences , vol.26 , Issue.2 , pp. 77-81
    • Blagosklonny, M.V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.