-
1
-
-
0242288463
-
Clioquinol effects on tissue chelatable zinc in mice
-
Nitzan YB, Sekler I, Frederickson CJ, Coulter DA, Balaji RV, Liang SL, Margulis A, Hershfinkel M and Silverman WF: Clioquinol effects on tissue chelatable zinc in mice. J Mol Med 81: 637-644, 2003.
-
(2003)
J Mol Med
, vol.81
, pp. 637-644
-
-
Nitzan, Y.B.1
Sekler, I.2
Frederickson, C.J.3
Coulter, D.A.4
Balaji, R.V.5
Liang, S.L.6
Margulis, A.7
Hershfinkel, M.8
Silverman, W.F.9
-
2
-
-
10744224267
-
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: A pilot phase 2 clinical trial
-
Ritchie CW, Bush AI, Mackinnon A, Macfarlane S, Mastwyk M, MacGregor L, Kiers L, Cherny R, Li QX, Tammer A, Carrington D, Mavros C, Volitakis I, Xilinas M, Ames D, Davis S, Beyreuther K, Tanzi RE and Masters CL: Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial. Arch Neurol 60: 1685-1691, 2003.
-
(2003)
Arch Neurol
, vol.60
, pp. 1685-1691
-
-
Ritchie, C.W.1
Bush, A.I.2
Mackinnon, A.3
Macfarlane, S.4
Mastwyk, M.5
MacGregor, L.6
Kiers, L.7
Cherny, R.8
Li, Q.X.9
Tammer, A.10
Carrington, D.11
Mavros, C.12
Volitakis, I.13
Xilinas, M.14
Ames, D.15
Davis, S.16
Beyreuther, K.17
Tanzi, R.E.18
Masters, C.L.19
-
3
-
-
18444399243
-
Treatment of Alzheimer's disease with clioquinol
-
Regland B, Lehmann W, Abedini I, Blennow K, Jonsson M, Karlsson I, Sjögren M, Wallin A, Xilinas M and Gottfries CG: Treatment of Alzheimer's disease with clioquinol. Dement Geriatr Cogn Disord 12: 408-414, 2001.
-
(2001)
Dement Geriatr Cogn Disord
, vol.12
, pp. 408-414
-
-
Regland, B.1
Lehmann, W.2
Abedini, I.3
Blennow, K.4
Jonsson, M.5
Karlsson, I.6
Sjögren, M.7
Wallin, A.8
Xilinas, M.9
Gottfries, C.G.10
-
4
-
-
14844293088
-
Anticancer metal compounds in NCI's tumor-screening database: Putative mode of action
-
DOI 10.1016/j.bcp.2005.01.001
-
Huang R, Wallqvist A and Covell DG: Anticancer metal compounds in NCI's tumor-screening database: putative mode of action. Biochem Pharmacol 69: 1009-1039, 2005. (Pubitemid 40349015)
-
(2005)
Biochemical Pharmacology
, vol.69
, Issue.7
, pp. 1009-1039
-
-
Huang, R.1
Wallqvist, A.2
Covell, D.G.3
-
5
-
-
17144404213
-
Anticancer activity of the antibiotic clioquinol
-
Ding WQ, Liu B, Vaught JL, Yamauchi H and Lind SE: Anticancer activity of the antibiotic clioquinol. Cancer Res 65: 3389-3395, 2005
-
(2005)
Cancer Res
, vol.65
, pp. 3389-3395
-
-
Ding, W.Q.1
Liu, B.2
Vaught, J.L.3
Yamauchi, H.4
Lind, S.E.5
-
6
-
-
62549083952
-
Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma
-
Mao X, Li X, Sprangers R, Wang X, Venugopal A, Wood T, Zhang Y, Kuntz DA, Coe E, Trudel S, Rose D, Batey RA, Kay LE and Schimmer AD: Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma. Leukemia 23: 585-590, 2009.
-
(2009)
Leukemia
, vol.23
, pp. 585-590
-
-
Mao, X.1
Li, X.2
Sprangers, R.3
Wang, X.4
Venugopal, A.5
Wood, T.6
Zhang, Y.7
Kuntz, D.A.8
Coe, E.9
Trudel, S.10
Rose, D.11
Batey, R.A.12
Kay, L.E.13
Schimmer, A.D.14
-
7
-
-
33847746963
-
Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts
-
Chen D, Cui QC, Yang H, Barrea RA, Sarkar FH, Sheng S, Yan B, Reddy GP and Dou QP: Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts. Cancer Res 67: 1636-1644, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 1636-1644
-
-
Chen, D.1
Cui, Q.C.2
Yang, H.3
Barrea, R.A.4
Sarkar, F.H.5
Sheng, S.6
Yan, B.7
Reddy, G.P.8
Dou, Q.P.9
-
8
-
-
58249091525
-
Clioquinol targets zinc to lysosomes in human cancer cells
-
Yu H, Zhou Y, Lind SE and Ding WQ: Clioquinol targets zinc to lysosomes in human cancer cells. Biochem J 417: 133-139, 2009.
-
(2009)
Biochem J
, vol.417
, pp. 133-139
-
-
Yu, H.1
Zhou, Y.2
Lind, S.E.3
Ding, W.Q.4
-
9
-
-
41549133200
-
Proteasome inhibitors in cancer therapy: Lessons from the first decade
-
Orlowski RZ and Kuhn DJ: Proteasome inhibitors in cancer therapy: lessons from the first decade. Clin Cancer Res 14: 1649-1657, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1649-1657
-
-
Orlowski, R.Z.1
Kuhn, D.J.2
-
11
-
-
2442464889
-
Apoptosis defects and chemotherapy resistance: Molecular interaction maps and networks
-
Pommier Y, Sordet O, Antony S, Hayward RL and Kohn KW: Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks. Oncogene 23: 2934-2949, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 2934-2949
-
-
Pommier, Y.1
Sordet, O.2
Antony, S.3
Hayward, R.L.4
Kohn, K.W.5
-
12
-
-
0029858387
-
TNF- And cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
-
Wang CY, Mayo MW and Baldwin AS Jr: TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science 274: 784-787, 1996.
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin Jr., A.S.3
-
13
-
-
0032728949
-
Mechanism of apoptosis induced by a lysosomotropic agent, L-leucyl-L-leucine methyl ester
-
Uchimoto T, Nohara H, Kamehara R, Iwamura M, Watanabe N and Kobayashi Y: Mechanism of apoptosis induced by a lysosomotropic agent, L-leucyl-L-leucine methyl ester. Apoptosis 4: 357-362, 1999.
-
(1999)
Apoptosis
, vol.4
, pp. 357-362
-
-
Uchimoto, T.1
Nohara, H.2
Kamehara, R.3
Iwamura, M.4
Watanabe, N.5
Kobayashi, Y.6
-
14
-
-
0027252876
-
Acridine orange-mediated photodamage to cultured cells
-
Zdolsek JM: Acridine orange-mediated photodamage to cultured cells. APMIS 101: 127-32, 1993.
-
(1993)
APMIS
, vol.101
, pp. 127-132
-
-
Zdolsek, J.M.1
-
15
-
-
33748302272
-
Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells
-
Ding WQ, Liu B, Vaught JL, Palmiter RD and Lind SE: Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells. Mol Cancer Ther 5: 1864-1872, 2006.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1864-1872
-
-
Ding, W.Q.1
Liu, B.2
Vaught, J.L.3
Palmiter, R.D.4
Lind, S.E.5
-
16
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin M: Nuclear factor-kappaB in cancer development and progression. Nature 441: 431-436, 2006.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
17
-
-
3242808193
-
Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity
-
DOI 10.1093/toxsci/kfh121
-
Thibodeau MS, Giardina C, Knecht DA, Helble J and Hubbard AK: Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity. Toxicol Sci 80: 34-48, 2004. (Pubitemid 38967394)
-
(2004)
Toxicological Sciences
, vol.80
, Issue.1
, pp. 34-48
-
-
Thibodeau, M.S.1
Giardina, C.2
Knecht, D.A.3
Helble, J.4
Hubbard, A.K.5
-
18
-
-
0032189348
-
Proteasome inhibitors: Valuable new tools for cell biologists
-
Lee DH and Goldberg AL: Proteasome inhibitors: valuable new tools for cell biologists. Trends Cell Biol 8: 397-403, 1998.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 397-403
-
-
Lee, D.H.1
Goldberg, A.L.2
-
19
-
-
38949096081
-
Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome
-
Ding WX and Yin XM: Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome. Autophagy 4: 141-50, 2008.
-
(2008)
Autophagy
, vol.4
, pp. 141-150
-
-
Ding, W.X.1
Yin, X.M.2
-
20
-
-
12844255134
-
Overcoming limitations of natural anticancer drugs by combining with artificial agents
-
DOI 10.1016/j.tips.2004.12.002, PII S0165614704003165
-
Blagosklonny MV: Overcoming limitations of natural anticancer drugs by combining with artificial agents. Trends Pharmacol Sci 26:77-81, 2005. (Pubitemid 40170169)
-
(2005)
Trends in Pharmacological Sciences
, vol.26
, Issue.2
, pp. 77-81
-
-
Blagosklonny, M.V.1
|