Case 23-2010: A 49-year-old man with erythrocytosis, perinephric fluid collections, and renal failure

New England Journal of Medicine

Volumn 363, Issue 5, 2010, Pages 463-475

  Bazari, Hasan ^a   Attar, Eyal C ^a,b   Dahl, Douglas M ^a,b   Uppot, Raul N ^a,b   Colvin, Robert B ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYHEMOGLOBIN; ERYTHROPOIETIN; JANUS KINASE 2;

ABDOMINAL RADIOGRAPHY; ABSCESS DRAINAGE; ACUTE KIDNEY FAILURE; ADULT; ARTICLE; BONE MARROW BIOPSY; CASE REPORT; ERYTHROCYTOSIS; GENE MUTATION; HUMAN; LABORATORY TEST; MALE; PERIRENAL ABSCESS; POLYCYTHEMIA VERA; PRIORITY JOURNAL; CLINICAL OBSERVATION; CLINICAL STUDY; CYSTIC LYMPHANGIOMA; DIAGNOSIS; DIFFERENTIAL DIAGNOSIS; EDEMA; HYDRONEPHROSIS; KIDNEY; KIDNEY DISEASE; LYMPHANGIECTASIS; MIDDLE AGED; PARAPROTEINEMIA; PATHOLOGY; POLYCYTHEMIA; RADIOGRAPHY;

DIAGNOSIS, DIFFERENTIAL; EDEMA; HUMANS; HYDRONEPHROSIS; KIDNEY; KIDNEY DISEASES; KIDNEY FAILURE, ACUTE; LYMPHANGIECTASIS; LYMPHANGIOMA, CYSTIC; MALE; MIDDLE AGED; PARAPROTEINEMIAS; POLYCYTHEMIA;

EID: 77955068558     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMcpc1004086     Document Type: Article

References (39)

1. Ashraf K, Raza SS, Ashraf O, Memon W, Memon A, Zubairi TA. Renal lymphangiectasia. Br J Radiol 2007;80(954):e117-e118.
2. Levine E. Renal lymphangiectasia. Radiology 1992;182:582. abstract.
3. Llorente JG, Garcia AD, Sacristan JS, Chicharro GN. Renal lymphangiectasia: radiologic diagnosis and evolution. Abdom Imaging 2002;27:637-9.
4. Meredith WT, Levine E, Ahlstrom NG, Grantham JJ. Exacerbation of familial renal lymphangiomatosis during pregnancy. AJR Am J Roentgenol 1988;151:965-6.
5. Murray KK, McLellan GL. Renal peripelvic lymphangiectasia: appearance at CT. Radiology 1991;180:455-6.
6. Upreti L, Dev A, Kumar Puri S. Imaging in renal lymphangiectasia: report of two cases and review of literature. Clin Radiol 2008;63:1057-62.
7. Younathan CM, Kaude JV. Renal peripelvic lymphatic cysts (lymphan giomas) associated with generalized lymphangiomatosis. Urol Radiol 1992;14:161-4.
8. Tefferi A, Vardiman JW. Classification and diagnosis of myeloproliferative neoplasms: the 2008 World Health Organization criteria and point-of-care diagnostic algorithms. Leukemia 2008;22:14-22.
9. Greer J, ed. Wintrobe's clinical hematology. 11th ed. Philadelphia: Lippincott Williams & Wilkins, 2004.
10. Ang SO, Chen H, Hirota K, et al. Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia. Nat Genet 2002;32:614-21. (Pubitemid 35435173)
11. Swerdlow SH, Campo E, Harris NL, et al., eds. WHO classification of tumours of haematopoietic and lymphoid tissues. 4th ed. Geneva: World Health Organization, 2008.
12. Krishnan SG, Valderrama E, Wagner JD, et al. Monoclonal gammopathy presenting as recurrent nephrotic syndrome: therapeutic implications. Am J Med Sci 2007;333:313-6. (Pubitemid 46787965)
13. Sanders PW. Renal involvement in plasma cell dyscrasias. Curr Opin Nephrol Hypertens 1993;2:246-52.
14. Gandhi GY, Basu R, Dispenzieri A, Basu A, Montori VM, Brennan MD. Endocrinopathy in POEMS syndrome: the Mayo Clinic experience. Mayo Clin Proc 2007;82:836-42. (Pubitemid 47015463)
15. Lee H, Meier FA, Ma CK, Ormsby AH, Lee MW. Eosinophilic globules in 3 cases of glomeruloid hemangioma of the head and neck: a characteristic offering more evidence for thanatosomes with or without POEMS. Am J Dermatopathol 2008;30:539-44.
16. Caglioti A, Esposito C, Fuiano G, et al. Prevalence of symptoms in patients with simple renal cysts. BMJ 1993;306:430-1. (Pubitemid 23045554)
17. Bisceglia M, Galliani CA, Senger C, Stallone C, Sessa A. Renal cystic diseases: a review. Adv Anat Pathol 2006;13:26-56.
18. Minor TX, Yeh BM, Horvai AE, Abrahams HM, Meng MV, Stoller ML. Symptomatic perirenal serous cysts of mullerian origin mimicking renal cysts on CT. AJR Am J Roentgenol 2004;183:1393-6.
19. Cadnapaphornchai MA, Ford DM, Tyson RW, Lum GM. Cystic renal lymphangiectasia presenting as renal insufficiency in childhood. Pediatr Nephrol 2000;15:129-31.
20. Meltzer E, Goshen E, Fridman E, Sidi Y. Diffuse lymphangiomatosis - a fatal case with atypical skeletal features. Am J Med Sci 2008;336:445-8.
21. Colucci S, Taraboletti G, Primo L, et al. Gorham-Stout syndrome: a monocyte-mediated cytokine propelled disease. J Bone Miner Res 2006;21:207-18.
22. Sarikaya B, Akturk Y, Bekar U, Topaloglu S. Bilateral renal lymphangiomatosis mimicking hydronephrosis: multi-detector CT urographic findings. Abdom Imaging 2006;31:732-4.
23. Burton IE, Sambrook P, McWilliam LJ. Secondary polycythaemia associated with bilateral renal lymphocoeles. Postgrad Med J 1994;70:515-7. (Pubitemid 24213359)
24. Mani NB, Sodhi KS, Singh P, Katariya S, Poddar U, Thapa BR. Renal lymph angiomatosis: a rare cause of bilateral nephromegaly. Australas Radiol 2003;47:184-7.
25. Shaheen M, Hilgarth KA, Hawes D, Badve S, Antony AC. A Mexican man with "too much blood." Lancet 2003;362:806.
26. Zapzalka DM, Krishnamurti L, Manivel JC, DiSandro MJ. Lymphangioma of the renal capsule. J Urol 2002;168:220.
27. Fakhouri F, Grunfeld JP, Hermine O, Delarue R. Angiotensin-converting enzyme inhibitors for secondary erythrocytosis. Ann Intern Med 2004;140:492-3.
28. Eisner BH, Tanrikut C, Dahl DM. Chyluria secondary to lymphorenal fistula. Kidney Int 2009;76:126.
29. Schacht V, Dadras SS, Johnson LA, Jackson DG, Hong YK, Detmar M. Upregulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors. Am J Pathol 2005;166:913-21.
30. Colvin RB. Emphatically lymphatic. J Am Soc Nephrol 2004;15:827-9.
31. Ishikawa Y, Akasaka Y, Kiguchi H, et al. The human renal lymphatics under normal and pathological conditions. Histopathology 2006;49:265-73.
32. Kerjaschki D, Regele HM, Moosberger I, et al. Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates. J Am Soc Nephrol 2004;15:603-12.
33. Rivalta F. Su due casi di cisti nel tessuto adiposo dell'ilo del rene. Arch Sci Med (Torino) 1889;13:73-85.
34. Henthorne JC. Peripelvic lymphatic cysts of the kidney. A review of the literature on peripelvic cysts. Am J Clin Pathol 1938;8:28-38.
35. Ueda S, Yanagida H, Sugimoto K, et al. Chronic renal insufficiency in a boy with cystic renal lymphangiectasia: morphological findings and long-term follow-up. Clin Nephrol 2007;68:416-21. (Pubitemid 350258772)
36. Wadhwa P, Kumar A, Sharma S, Dogra PN, Hemal AK. Renal lymphangiomatosis: imaging and management of a rare renal anomaly. Int Urol Nephrol 2007;39:365-8.
37. Mattoo TK, Giangreco AB, Afzal M, Akhtar M. Cystic lymphangiectasia of the kidneys in an infant with nephrotic syndrome. Pediatr Nephrol 1990;4:228-32.
38. Sollinger HW, Starling JR, Oberley T, Glass NR, Belzer FO. Severe "weeping" kidney disease after transplantation: a case report. Transplant Proc 1983;15:2157-60.
39. Langer RM, Kahan BD. Incidence, therapy, and consequences of lymphocele after sirolimus-cyclosporine-prednisone immunosuppression in renal transplant recipients. Transplantation 2002;74:804-8.