CESAR: deliverance or just the beginning?

Critical Care and Resuscitation

Volumn 12, Issue 2, 2010, Pages 75-77

  Pellegrino, Vincent A ^a   Davies, Andrew R ^a  

^a ALFRED HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT RESPIRATORY DISTRESS SYNDROME; EXTRACORPOREAL OXYGENATION; HUMAN; MORTALITY; NOTE;

EXTRACORPOREAL MEMBRANE OXYGENATION; HUMANS; RESPIRATORY DISTRESS SYNDROME, ADULT;

EID: 77955065321     PISSN: 14412772     EISSN: 26529335     Source Type: Journal    
DOI: 10.1016/S1441-2772(23)01517-X     Document Type: Editorial

References (21)

1. Gille, J.P., Bagniewski, A.M., Ten years of use of extracorporeal membrane oxygenation (ECMO) in the treatment of acute respiratory insufficiency (ARI). Trans Am Soc Artif Intern Organs 22 (1976), 102–109.
2. Worrall, J., Evidence and ethics in medicine. Perspect Biol Med 51 (2008), 418–431.
3. Hill, J.D., Ratliff, J.L., Fallat, R.J., et al. Prognostic factors in the treatment of acute respiratory insufficiency with long-term extracorporeal oxygenation. J Thorac Cardiovasc Surg 68 (1974), 905–917.
4. Bartlett, R.H., Gazzaniga, A.B., Fong, S.W., Burns, N.E., Prolonged extracorporeal cardiopulmonary support in man. J Thorac Cardiovasc Surg 68 (1974), 918–932.
5. 2 removal in severe acute respiratory failure. JAMA 256 (1986), 881–886.
6. Zapol, W.M., Snider, M.T., Hill, J.D., et al. Extracorporeal membrane oxygenation in severe acute respiratory failure. A randomized prospective study. JAMA 242 (1979), 2193–2196.
7. 2 removal for adult respiratory distress syndrome. Am J Respir Crit Care Med 149 (1994), 295–305.
8. ANZ ECMO Influenza Investigators, Extracorporeal membrane oxygenation for 2009 influenza A(H1N1) acute respiratory distress syndrome. JAMA 302 (2009), 1888–1895.
9. Hastings, S.L., Pellegrino, V.A., Preovolos, A., Salamonsen, R.F., Survey of adult extracorporeal membrane oxygenation (ECMO) practice and attitudes among Australian and New Zealand intensivists. Crit Care Resusc 10 (2008), 42–46.
10. Linden, V.B., Lidegran, M.K., Frisen, G., et al. ECMO in ARDS: a longterm follow-up study regarding pulmonary morphology and function and health-related quality of life. Acta Anaesthesiol Scand 53 (2009), 489–495.
11. Peek, G.J., Mugford, M., Tiruvoipati, R., et al. Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial. Lancet 374 (2009), 1351–1363.
12. Zwischenberger, J.B., Lynch, J.E., Will CESAR answer the adult ECMO debate?. Lancet 374 (2009), 1307–1308.
13. Moran, J.L., Chalwin, R.P., Graham, P.L., Extracorporeal membrane oxygenation (ECMO) reconsidered. Crit Care Resusc 12 (2010), 131–135.
14. LeLorier, J., Gregoire, G., Benhaddad, A., et al. Discrepancies between meta-analyses and subsequent large randomized, controlled trials. N Engl J Med 337 (1997), 536–542.
15. Flather, M.D., Farkouh, M.E., Pogue, J.M., Yusuf, S., Strengths and limitations of meta-analysis: larger studies may be more reliable. Control Clin Trials 18 (1997), 568–579 discussion 661-6.
16. Tomlinson, G., Detsky, A.S., Composite end points in randomized trials: there is no free lunch. JAMA 303 (2010), 267–268.
17. UK collaborative randomised trial of neonatal extracorporeal membrane oxygenation. UK Collaborative ECMO Trial Group. Lancet 348 (1996), 75–82.
18. CESAR: Conventional Ventilation or ECMO for Severe Adult Respiratory Failure, A collaborative randomised controlled trial. Protocol, 2003 February http://cesar.lshtm.ac.uk/protocolapril2004.pdf.
19. Berwick, D.M., The science of improvement. JAMA 299 (2008), 1182–1184.
20. Hillman, K., Chen, J., Cretikos, M., et al. Introduction of the medical emergency team (MET) system: a cluster-randomised controlled trial. Lancet 365 (2005), 2091–2097.
21. Davies, A., Jones, D., Gattas, D., Extracorporeal membrane oxygenation for ARDS due to 2009 influenza A(H1N1) [letter in reply]. JAMA, 303, 2010, 942.