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Volumn 45, Issue 9, 2010, Pages 1577-1581

Scopolamine, anisodamine and hyoscyamine production by Brugmansia candida hairy root cultures in bioreactors

Author keywords

Anisodamine; Brugmansia candida; Hairy root cultures; Hyoscyamine; Scopolamine; Stirred tank bioreactor

Indexed keywords

ALTERNATIVE PRODUCTION SYSTEMS; ANISODAMINE; BIOREACTOR CULTURES; CANDIDA; CONCENTRATION OF; ERLENMEYER FLASKS; HAIRY ROOT CULTURE; HAIRY ROOTS; PHARMACEUTICAL PRODUCTION; SCALE-UP; SCALING-UP; SOLANACEAE; STIRRED TANK; STIRRED TANK BIOREACTORS; TROPANE ALKALOIDS;

EID: 77955052088     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2010.06.002     Document Type: Article
Times cited : (45)

References (35)
  • 1
    • 0003189106 scopus 로고
    • Acción farmacodinámica de las flores de Brugmansia candida
    • Roses O.E., Miño J., Villamil E.C. Acción farmacodinámica de las flores de Brugmansia candida. Fitoterapia 1988, 59:120-127.
    • (1988) Fitoterapia , vol.59 , pp. 120-127
    • Roses, O.E.1    Miño, J.2    Villamil, E.C.3
  • 2
    • 0027376143 scopus 로고
    • Tropane alkaloid production in transformed root cultures of Brugmansia candida
    • Giulietti A.M., Parr A.J., Rhodes M.J. Tropane alkaloid production in transformed root cultures of Brugmansia candida. Planta Med 1993, 59:428-431.
    • (1993) Planta Med , vol.59 , pp. 428-431
    • Giulietti, A.M.1    Parr, A.J.2    Rhodes, M.J.3
  • 4
    • 0027429924 scopus 로고
    • Anisodamine causes acyl chain interdigitation in phosphatidylglycerol
    • Wang P.Y., Chen J.W., Hwang F. Anisodamine causes acyl chain interdigitation in phosphatidylglycerol. FEBS Lett 1993, 332:193-196.
    • (1993) FEBS Lett , vol.332 , pp. 193-196
    • Wang, P.Y.1    Chen, J.W.2    Hwang, F.3
  • 5
    • 0030969850 scopus 로고    scopus 로고
    • Anisodamine restores bowel circulation in burn shock
    • Sheng C.Y., Gao W.Y., Guo Z.R., He L.X. Anisodamine restores bowel circulation in burn shock. Burns 1997, 23:142-146.
    • (1997) Burns , vol.23 , pp. 142-146
    • Sheng, C.Y.1    Gao, W.Y.2    Guo, Z.R.3    He, L.X.4
  • 6
    • 0037192564 scopus 로고    scopus 로고
    • Anisodamine inhibits cardiac contraction and intracellular Ca(2+) transients in isolated adult rat ventricular myocytes
    • Norby F.L., Ren J. Anisodamine inhibits cardiac contraction and intracellular Ca(2+) transients in isolated adult rat ventricular myocytes. Eur J Pharmacol 2002, 439:21-25.
    • (2002) Eur J Pharmacol , vol.439 , pp. 21-25
    • Norby, F.L.1    Ren, J.2
  • 7
    • 0037527563 scopus 로고    scopus 로고
    • Differentiating effects of anisodamine on cognitive amelioration and peripheral muscarinic side effects induced by pilocarpine in mice
    • Wang H., Lu Y., Chen H.Z. Differentiating effects of anisodamine on cognitive amelioration and peripheral muscarinic side effects induced by pilocarpine in mice. Neurosci Lett 2003, 344:173-176.
    • (2003) Neurosci Lett , vol.344 , pp. 173-176
    • Wang, H.1    Lu, Y.2    Chen, H.Z.3
  • 8
    • 33745022294 scopus 로고    scopus 로고
    • Asymmetric synthesis of anisodine
    • Wu Y.F., Lü W., Lu Q., Zhang W.S. Asymmetric synthesis of anisodine. Chin Chem Lett 2005, 16:1287-1289.
    • (2005) Chin Chem Lett , vol.16 , pp. 1287-1289
    • Wu, Y.F.1    Lü, W.2    Lu, Q.3    Zhang, W.S.4
  • 9
    • 33846696351 scopus 로고    scopus 로고
    • Diastereomeric and enantiomeric high-performance liquid chromatographic separation of synthetic anisodamine
    • Yang L.M., Xie Y.F., Chen H.Z., Lu Y. Diastereomeric and enantiomeric high-performance liquid chromatographic separation of synthetic anisodamine. J Pharm Biomed Anal 2007, 43:905-909.
    • (2007) J Pharm Biomed Anal , vol.43 , pp. 905-909
    • Yang, L.M.1    Xie, Y.F.2    Chen, H.Z.3    Lu, Y.4
  • 10
    • 0032428739 scopus 로고    scopus 로고
    • Effects of chemicals on alkaloid production by transformed roots of Belladonna
    • Lee K.T., Yamakawa T., Kodama T., Shimomura K. Effects of chemicals on alkaloid production by transformed roots of Belladonna. Phytochemistry 1998, 49:2343-2347.
    • (1998) Phytochemistry , vol.49 , pp. 2343-2347
    • Lee, K.T.1    Yamakawa, T.2    Kodama, T.3    Shimomura, K.4
  • 11
    • 34547817167 scopus 로고    scopus 로고
    • Simultaneous electrochemiluminiscence detection of anisodamine, atropine and scopolamine in Flos daturae by capillary electrophoresis using b-cyclodextrin as additive
    • Li J., Chun Y., Jua H. Simultaneous electrochemiluminiscence detection of anisodamine, atropine and scopolamine in Flos daturae by capillary electrophoresis using b-cyclodextrin as additive. Electroanalysis 2007, 19:1569-1574.
    • (2007) Electroanalysis , vol.19 , pp. 1569-1574
    • Li, J.1    Chun, Y.2    Jua, H.3
  • 13
    • 0000025904 scopus 로고
    • Hyoscyamine 6beta-hydroxylase, a 2-oxoglutarate-dependent dioxygenase, in alkaloid-producing root cultures
    • Hashimoto T., Yamada Y. Hyoscyamine 6beta-hydroxylase, a 2-oxoglutarate-dependent dioxygenase, in alkaloid-producing root cultures. Plant Physiol 1986, 81:619-625.
    • (1986) Plant Physiol , vol.81 , pp. 619-625
    • Hashimoto, T.1    Yamada, Y.2
  • 15
    • 24944474802 scopus 로고    scopus 로고
    • Simultaneous analysis of hyoscyamine, scopolamine, 6beta-hydroxyhyoscyamine and apoatropine in Solanaceous hairy roots by reversed-phase high-performance liquid chromatography
    • Kursinszki L., Hank H., Laszlo I., Szoke E. Simultaneous analysis of hyoscyamine, scopolamine, 6beta-hydroxyhyoscyamine and apoatropine in Solanaceous hairy roots by reversed-phase high-performance liquid chromatography. J Chromatogr A 2005, 1091:32-39.
    • (2005) J Chromatogr A , vol.1091 , pp. 32-39
    • Kursinszki, L.1    Hank, H.2    Laszlo, I.3    Szoke, E.4
  • 16
    • 33947581846 scopus 로고    scopus 로고
    • The pharmacological properties of anisodamine
    • Poupko J.M., Baskin S.I., Moore E. The pharmacological properties of anisodamine. J Appl Toxicol 2006, 27:116-121.
    • (2006) J Appl Toxicol , vol.27 , pp. 116-121
    • Poupko, J.M.1    Baskin, S.I.2    Moore, E.3
  • 17
    • 34247631684 scopus 로고    scopus 로고
    • Hairy root type plant in vitro systems as sources of bioactive substances
    • Georgiev M.I., Pavlov A.I., Bley T. Hairy root type plant in vitro systems as sources of bioactive substances. Appl Microbiol Biotechnol 2007, 74:1175-1185.
    • (2007) Appl Microbiol Biotechnol , vol.74 , pp. 1175-1185
    • Georgiev, M.I.1    Pavlov, A.I.2    Bley, T.3
  • 18
    • 44049093323 scopus 로고    scopus 로고
    • Novel technique for scaling up of micropropagated Ruta graveolens shoots using liquid culture systems: a step towards commercialization
    • Diwan R., Malpathak N. Novel technique for scaling up of micropropagated Ruta graveolens shoots using liquid culture systems: a step towards commercialization. Nat Biotechnol 2008, 25:85-91.
    • (2008) Nat Biotechnol , vol.25 , pp. 85-91
    • Diwan, R.1    Malpathak, N.2
  • 22
    • 48449087525 scopus 로고    scopus 로고
    • Design of bioreactors suitable for plant cell and tissue cultures
    • Eibl R., Eibl D. Design of bioreactors suitable for plant cell and tissue cultures. Phytochem Rev 2008, 7:593-598.
    • (2008) Phytochem Rev , vol.7 , pp. 593-598
    • Eibl, R.1    Eibl, D.2
  • 23
    • 33746066347 scopus 로고    scopus 로고
    • Tailoring tropane alkaloid accumulation in transgenic hairy roots of Atropa baetica by over-expressing the gene encoding hyoscyamine 6beta-hydroxylase
    • Zarate R., el Jaber-Vazdekis N., Medina B., Ravelo A.G. Tailoring tropane alkaloid accumulation in transgenic hairy roots of Atropa baetica by over-expressing the gene encoding hyoscyamine 6beta-hydroxylase. Biotechnol Lett 2006, 28:1271-1277.
    • (2006) Biotechnol Lett , vol.28 , pp. 1271-1277
    • Zarate, R.1    el Jaber-Vazdekis, N.2    Medina, B.3    Ravelo, A.G.4
  • 24
    • 0001120062 scopus 로고
    • Variation in tropane alkaloid accumulation within the Solanaceae and strategies for its exploitation
    • Parr A.J., Payne J., Eagles J., Chapman B.T., Robins R.J., Rhodes M.J.C. Variation in tropane alkaloid accumulation within the Solanaceae and strategies for its exploitation. Phytochemistry 1990, 29:2545-2550.
    • (1990) Phytochemistry , vol.29 , pp. 2545-2550
    • Parr, A.J.1    Payne, J.2    Eagles, J.3    Chapman, B.T.4    Robins, R.J.5    Rhodes, M.J.C.6
  • 25
    • 33749946901 scopus 로고
    • Colorimetric method for determination of sugars and related substances
    • Dubois M., Gilles K.A., Hamilton J.K., Rebers P.A., Smith F. Colorimetric method for determination of sugars and related substances. Anal Chem 1956, 28:350-356.
    • (1956) Anal Chem , vol.28 , pp. 350-356
    • Dubois, M.1    Gilles, K.A.2    Hamilton, J.K.3    Rebers, P.A.4    Smith, F.5
  • 26
    • 46049083246 scopus 로고    scopus 로고
    • Expression of Brugmansia candida hyoscyamine 6beta-hydroxylase gene in Saccharomyces cerevisiae and its potential use as biocatalyst
    • Cardillo A.B., Rodriguez Talou J., Giulietti A.M. Expression of Brugmansia candida hyoscyamine 6beta-hydroxylase gene in Saccharomyces cerevisiae and its potential use as biocatalyst. Microb Cell Fact 2008, 7:17.
    • (2008) Microb Cell Fact , vol.7 , pp. 17
    • Cardillo, A.B.1    Rodriguez Talou, J.2    Giulietti, A.M.3
  • 27
    • 0029201418 scopus 로고
    • Advantage and limitations in the use of hairy roots cultures for the production of tropane alkaloids: use of anti-auxins in the maintenance of normal root morphology
    • Pitta-Alvarez S.A., Giulietti A.M. Advantage and limitations in the use of hairy roots cultures for the production of tropane alkaloids: use of anti-auxins in the maintenance of normal root morphology. In Vitro Cell Dev Biol Plant 1995, 31:215-220.
    • (1995) In Vitro Cell Dev Biol Plant , vol.31 , pp. 215-220
    • Pitta-Alvarez, S.A.1    Giulietti, A.M.2
  • 28
    • 0034135614 scopus 로고    scopus 로고
    • The influence of different biotic and abiotic elicitors on the production and profile of tropane alkaloids in hairy root cultures of Brugmansia candida
    • Pitta-Alvarez S.I., Spollansky T.C., Giulietti A.M. The influence of different biotic and abiotic elicitors on the production and profile of tropane alkaloids in hairy root cultures of Brugmansia candida. Enzyme Microb Technol 2000, 26:252-258.
    • (2000) Enzyme Microb Technol , vol.26 , pp. 252-258
    • Pitta-Alvarez, S.I.1    Spollansky, T.C.2    Giulietti, A.M.3
  • 30
    • 64049099060 scopus 로고    scopus 로고
    • Methyl jasmonate effect on diterpenoid accumulation in Salvia sclarea hairy root culture in shake flasks and sprinkle bioreactor
    • Kuźma Ł., Bruchajzer E., Wysokińska H. Methyl jasmonate effect on diterpenoid accumulation in Salvia sclarea hairy root culture in shake flasks and sprinkle bioreactor. Enzyme Microb Technol 2009, 44:406-410.
    • (2009) Enzyme Microb Technol , vol.44 , pp. 406-410
    • Kuźma, Ł.1    Bruchajzer, E.2    Wysokińska, H.3
  • 31
    • 0025700262 scopus 로고
    • Determination of growth rate for plant cell cultures: comparative studies
    • Ryu D.D., Lee S.O., Romani R.J. Determination of growth rate for plant cell cultures: comparative studies. Biotechnol Bioeng 1990, 35:305-311.
    • (1990) Biotechnol Bioeng , vol.35 , pp. 305-311
    • Ryu, D.D.1    Lee, S.O.2    Romani, R.J.3
  • 32
    • 0037615212 scopus 로고    scopus 로고
    • Growth and ginsenoside production in hairy root cultures of Panax ginseng using a novel bioreactor
    • Palazón J., Mallol A., Eibl R., Lettenbauer C., Cusidó R.M., Piñol M.T. Growth and ginsenoside production in hairy root cultures of Panax ginseng using a novel bioreactor. Planta Med 2003, 69:344-349.
    • (2003) Planta Med , vol.69 , pp. 344-349
    • Palazón, J.1    Mallol, A.2    Eibl, R.3    Lettenbauer, C.4    Cusidó, R.M.5    Piñol, M.T.6
  • 33
    • 13844266844 scopus 로고    scopus 로고
    • Comparative evaluation of bioreactor design using Tagetes patula L. hairy roots as a model system
    • Suresh B., Bais H.P., Raghavarao K.S.M.S., Ravishankar G.A., Ghildyal N.P. Comparative evaluation of bioreactor design using Tagetes patula L. hairy roots as a model system. Process Biochem 2005, 40:1509-1515.
    • (2005) Process Biochem , vol.40 , pp. 1509-1515
    • Suresh, B.1    Bais, H.P.2    Raghavarao, K.S.M.S.3    Ravishankar, G.A.4    Ghildyal, N.P.5
  • 34
    • 33845767078 scopus 로고    scopus 로고
    • Production of iridoids and phenolics by transformed Harpagophytum procumbens root cultures
    • Georgiev M.I., Heinrich M., Kerns G., Pavlov A.I., Bley T. Production of iridoids and phenolics by transformed Harpagophytum procumbens root cultures. Eng Life Sci 2006, 6:593-596.
    • (2006) Eng Life Sci , vol.6 , pp. 593-596
    • Georgiev, M.I.1    Heinrich, M.2    Kerns, G.3    Pavlov, A.I.4    Bley, T.5
  • 35
    • 0025325736 scopus 로고
    • Growth and hyoscyamine production of 'hairy root' cultures of Datura stramonium in a modified stirred tank reactor
    • Hilton M.G., Rhodes M.J. Growth and hyoscyamine production of 'hairy root' cultures of Datura stramonium in a modified stirred tank reactor. Appl Microbiol Biotechnol 1990, 33:132-138.
    • (1990) Appl Microbiol Biotechnol , vol.33 , pp. 132-138
    • Hilton, M.G.1    Rhodes, M.J.2


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