The influence of different biotic and abiotic elicitors on the production and profile of tropane alkaloids in hairy root cultures of Brugmansia candida

Enzyme and Microbial Technology

Volumn 26, Issue 2-4, 2000, Pages 252-258

  Pitta Alvarez, Sandra I ^a   Spollansky, Tatiana C ^a   Giulietti, Ana M ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

AgNO3; CaCl2; CdCl2; Hyoscyamine; Salicylic acid; Scopolamine; Stress agent; Yeast extract

Indexed keywords

HYOSCYAMINE; SCOPOLAMINE; TROPANE ALKALOID;

ARTICLE; DRUG SYNTHESIS; METABOLIC ACTIVATION; NONHUMAN; PLANT CELL; PLANT ROOT;

BRUGMANSIA CANDIDA; CANDIDA;

AMINES; BIOSYNTHESIS; BIOTECHNOLOGY; CADMIUM COMPOUNDS; CALCIUM COMPOUNDS; GROWTH KINETICS; METABOLISM; ORGANIC ACIDS; PRODUCTIVITY; SILVER COMPOUNDS; YEAST;

ABIOTIC ELICITORS; ALKALOIDS; BIOTIC ELICITORS; HYOSCYAMINE; SCOPOLAMINE;

PLANT CELL CULTURE;

EID: 0034135614     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0141-0229(99)00137-4     Document Type: Article

References (37)

1. Kanegae T., Kajiya H., Amano Y., Hashimoto T., Yamada Y. Species-dependent expression of the hyoscyamine-6β-hydroxylase gene in the pericycle. Plant Physiol. 105:1994;483-490.
2. Yamada Y., Yun D.J., Hashimoto T. Genetic engineering of medicinal plants for tropane alkaloid production. Ryu D.D.Y., Furusaki S. Advances in Plant Biotechnology. 1994;83-93 Elsevier Science, Amsterdam.
3. Hashimoto T., Yamada Y. Scopolamine production in suspension cultures and redifferentiated roots of Hyoscyamus niger. Planta Med. 47:1983;195-199.
4. Payne J., Hamill J.D., Robins R.J., Rhodes M.J.C. Production of hyoscyamine by hairy root cultures of Datura stramonium. Planta Med. 53:1987;474-478.
5. Maldonado-Mendoza IE, Ayora-Talavera T, Loyola-Vargas VM. Tropane alkaloid production in Datura stramonium root cultures. In Vitro Cell Dev Biol 1992;28P:67-72.
6. Pitta-Alvarez S.I., Giulietti A.M. Advantages and limitations in the use of hairy root cultures for the production of tropane alkaloids use of anti-auxins in the maintenance of normal root morphology . In Vitro Cell Dev Biol Plant. 31:1995;215-220.
7. Robins R.J., Bent E.G., Rhodes M.J.C. Studies on the biosynthesis of tropane alkaloids by Datura stramonium L. transformed root cultures. 3. The relationship between morphological integrity and alkaloid biosynthesis. Planta. 185:1991;385-390.
8. Flores H.E., Hoy M.W., Pickard J.J. Secondary metabolites from root cultures. Trends Biotechnol. 5:1987;64-68.
9. Buitelaar R.M., Tramper J. Strategies to improve the production of secondary metabolites with plant cell cultures a literature review . J Biotechnol. 23:1992;111-141.
10. Darvill A.G., Albersheim P. Phytoalexins and their elicitors - -a defense against microbial infections in plants. Annu Rev Plant Physiol. 35:1984;243-275.
11. Ebel J., Scheel D. Signals in host-parasite interactions. Carroll G.C., Tudzynski P. The mycota plant relationships, part A, vol. V. 1997;85-105 Springer Verlag, Berlin.
12. Eilert U. Elicitation: methodology and aspects of application. In: Constabel F, Vasil IK, editors. Cell culture and somatic cell genetics of plants, vol. 4. San Diego: Academic Press, 1987. p. 153-96.
13. Nishi A. Effect of elicitors on the production of secondary metabolites. In: DDY Ryu, S Furasaki, editors. Advances in plant biotechnology. Amsterdam: Elsevier Science, 1994. p. 135-51.
14. Benhamou N. Elicitor-induced plant defence pathways. Trends Plant Sci. 1:1996;233-240.
15. Shirasu K., Nakajima H., Krishnamachari Rajasekhar V., Dixon R.A., Lamb C. Salicylic acid potentiates an agonist-dependent gain control that amplifies pathogen signals in the activation of defense mechanisms. Plant Cell. 9:1997;261-270.
16. Brodelius P., Collinge M.A., Funk C., Gügler K., Marques I. Studies on alkaloid formation in plant cell cultures after treatment with a yeast elicitor. Kurz W.G.W. Primary and secondary metabolism of plant cell cultures. 1989;190-199 Springer-Verlag, Berlin.
17. Buitelaar R.M., Cesario M.T., Tramper J. Elicitation of thiophene production by hairy roots of Tagetes patula. Enzyme Microb Technol. 14:1992;2-7.
18. Vázquez-Flota F, Moreno-Valenzuela O, Miranda-Ham ML, Coello-Coello J, Loyola-Vargas VM. Catharanthine and ajmalicine synthesis in Catharanthus roseus hairy root cultures. Medium optimization and elicitation. Plant Cell, Tissue Organ Culture 1994;38:273-9.
19. Ciddi V., Srinivasan V., Shuler M.L. Elicitation of Taxus sp. cell culture for production of taxol. Biotechnol Lett. 17:1995;1343-1346.
20. Signs MW, Flores HE. Elicitation of sesquiterpene phytoalexin biosynthesis in transformed root cultures of Hyoscyamus muticus L. Plant Physiol 1989;89S:135.
21. Furze M.J., Rhodes M.J.C., Parr A.J., Robins R.J., Whitehead I.A., Threlfall D.R. Abiotic factors elicit sesquiterpenoid production but not alkaloid production in transformed root cultures of Datura stramonium. Plant Cell Reports. 10:1991;111-114.
22. Sevón N., Hiltunen R., Oksman-Caldentey K.M. Chitosan increases hyoscyamine content in hairy root cultures of Hyoscyamus muticus. Pharm Pharmacol Lett. 2:1992;96-99.
23. Ballica R., Ryu D.D.Y., Kado C.I. Tropane alkaloid production in Datura stramonium suspension cultures elicitor and precursor effects . Biotechnol Bioengin. 41:1993;1075-1081.
24. Gamborg O.L., Miller R.A., Ojima K. Nutrient requirements of suspension cultures of soybean root cells. Exp Cell Res. 50:1968;151-158.
25. Parr A.J., Payne J., Eagle J., Chapman B., Robins R.J., Rhodes M.J.C. Variation in tropane alkaloid accumulation within the Solanaceae and strategies for its exploitation. Phytochemistry. 29:1990;2545-2550.
26. Mano Y., Nabeshima S., Matsui C., Ohkawa H. Production of tropane alkaloids by hairy root cultures of Scopolia japonica. Agric Biol Chem. 50:1986;2715-2722.
27. Tukey J.W. Some selected quick and easy methods of statistical analysis. Trans NY Acad Sci Ser II. 16:1953;88-97.
28. Durner J., Shah J., Klessig D.F. Salicylic acid and disease resistance in plants. Trends Plant Sci. 2:1997;266-274.
29. Shualev V., Leon J., Raskin I. Is salicylic acid a translocated signal of systemic acquired resistance in tobacco? Plant Cell. 7:1995;1691-1701.
30. Malamy J., Sánchez-Casas P., Hennig J., Guo A., Klessig D. Dissection of the salicylic acid signaling pathway in tobacco. Mol Plant-Microbe Interactions. 9:1996;474-482.
31. Dong X. SA, JA, ethylene, and disease resistance in plants. Curr Opin Plant Biol. 1:1998;316-323.
32. O'Donnell P.J., Calvert C., Atzorn R., Wasternack C., Leyser H.M.O., Bowles D.J. Ethylene as a signal mediating the wound response of tomato plants. Science. 274:1996;1914-1917.
33. Suzuki T., Mori H., Yamame T., Shimuzu S. Automatich supplementation of minerals in fed-batch culture to high cell mass concentration. Biotech Bioeng. 27:1985;192-201.
34. Ertola R.J., Hours R. Role of yeast extract components in microbial cultures not associated with amino acids, vitamins and minerals a review . Appl Biol Sci. 4:1998;1-15.
35. Gontier E., Sangwan B.S., Barbotin J.N. Effects of calcium, alginate, and calcium alginate immobilization on growth and tropane alkaloid levels of a stable suspension cell line of Datura innoxia Mill. Plant Cell Reports. 13:1994;533-536.
36. Stroinski A., Floryszak-Wieczorek J. Effects of cadmium on the host-pathogen system. III. Influence of cadmium and Phythophthora infestans on membrane permeability of potato leaves. Biochem Physiol Pflanzen. 186:1990;417-421.
37. Stroinski A., Floryszak-Wieczorek J. Effects of cadmium on the host-pathogen system. IV. Influence of cadmium on membrane permeability of potato tuber-Phythophthora infestans system. Biochem J Plant Physiol. 142:1993;575-578.