Coagulation procofactor activation by factor XIa

Journal of Thrombosis and Haemostasis

Volumn 8, Issue 7, 2010, Pages 1532-1539

  Whelihan, M F ^a   Orfeo, T ^a   Gissel, M T ^a   Mann, K G ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

Activated partial thromboplastin time; Factor V; Factor VIII; Factor XI; Intrinsic pathway

Indexed keywords

BLOOD CLOTTING FACTOR 11A;

ARTICLE; BLOOD CLOTTING; CATALYSIS; HUMAN; KINETICS; PARTIAL THROMBOPLASTIN TIME; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL;

BINDING SITES; BLOOD COAGULATION TESTS; CATALYSIS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; FACTOR V; FACTOR VIII; FACTOR XIA; HUMANS; KINETICS; PARTIAL THROMBOPLASTIN TIME;

EID: 77955034572     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2010.03899.x     Document Type: Article

References (56)

1. Guasch JF, Cannegieter S, Reitsma PH, van't Veer-Korthof ET, Bertina RM. Severe coagulation factor V deficiency caused by a 4 bp deletion in the factor V gene. Br J Haematol 1998, 101:32-9.
2. Nesheim ME, Mann KG. Thrombin-catalyzed activation of single chain bovine factor V. J Biol Chem 1979, 254:1326-34.
3. Suzuki K, Dahlback B, Stenflo J. Thrombin-catalyzed activation of human coagulation factor V. J Biol Chem 1982, 257:6556-64.
4. Eaton D, Rodriguez H, Vehar GA. Proteolytic processing of human factor VIII. Correlation of specific cleavages by thrombin, factor Xa, and activated protein C with activation and inactivation of factor VIII coagulant activity. Biochemistry 1986, 25:505-12.
5. Myles T, Yun TH, Leung LL. Structural requirements for the activation of human factor VIII by thrombin. Blood 2002, 100:2820-6.
6. Keller FG, Ortel TL, Quinn-Allen MA, Kane WH. Thrombin-catalyzed activation of recombinant human factor V. Biochemistry 1995, 34:4118-24.
7. Brummel KE, Paradis SG, Butenas S, Mann KG. Thrombin functions during tissue factor-induced blood coagulation. Blood 2002, 100:148-52.
8. Lawson JH, Kalafatis M, Stram S, Mann KG. A model for the tissue factor pathway to thrombin. I. An empirical study. J Biol Chem 1994, 269:23357-66.
9. Nesheim ME, Taswell JB, Mann KG. The contribution of bovine Factor V and Factor Va to the activity of prothrombinase. J Biol Chem 1979, 254:10952-62.
10. Rawala-Sheikh R, Ahmad SS, Ashby B, Walsh PN. Kinetics of coagulation factor X activation by platelet-bound factor IXa. Biochemistry 1990, 29:2606-11.
11. Renne T, Nieswandt B, Gailani D. The intrinsic pathway of coagulation is essential for thrombus stability in mice. Blood Cells Mol Dis 2006, 36:148-51.
12. Tucker EI, Marzec UM, White TC, Hurst S, Rugonyi S, McCarty OJ, Gailani D, Gruber A, Hanson SR. Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI. Blood 2009, 113:936-44.
13. Schmaier AH. The elusive physiologic role of Factor XII. J Clin Invest 2008, 118:3006-9.
14. Gailani D, Renne T. Intrinsic pathway of coagulation and arterial thrombosis. Arterioscler Thromb Vasc Biol 2007, 27:2507-13.
15. Tripodi A, Mannucci PM. Activated partial thromboplastin time (APTT). New indications for an old test? J Thromb Haemost 2006, 4:750-1.
16. Fujikawa K, Legaz ME, Kato H, Davie EW. The mechanism of activation of bovine factor IX (Christmas factor) by bovine factor XIa (activated plasma thromboplastin antecedent). Biochemistry 1974, 13:4508-16.
17. Kaplan AP, Silverberg M. The coagulation-kinin pathway of human plasma. Blood 1987, 70:1-15.
18. Kaplan AP, Joseph K, Shibayama Y, Reddigari S, Ghebrehiwet B, Silverberg M. The intrinsic coagulation/kinin-forming cascade: assembly in plasma and cell surfaces in inflammation. Adv Immunol 1997, 66:225-72.
19. Macfarlane RG. An enzyme cascade in the blood clotting mechanism, and its function as a biochemical amplifier. Nature 1964, 202:498-9.
20. Osterud B, Bouma BN, Griffin JH. Human blood coagulation factor IX. Purification, properties, and mechanism of activation by activated factor XI. J Biol Chem 1978, 253:5946-51.
21. Fay PJ. Activation of factor VIII and mechanisms of cofactor action. Blood Rev 2004, 18:1-15.
22. Bouma BN, Griffin JH. Human blood coagulation factor XI. Purification, properties, and mechanism of activation by activated factor XII. J Biol Chem 1977, 252:6432-7.
23. Lindquist PA, Fujikawa K, Davie EW. Activation of bovine factor IX (Christmas factor) by factor XIa (activated plasma thromboplastin antecedent) and a protease from Russell's viper venom. J Biol Chem 1978, 253:1902-9.
24. Thompson RE, Mandle R, Kaplan AP. Association of factor XI and high molecular weight kininogen in human plasma. J Clin Invest 1977, 60:1376-80.
25. Katzmann JA, Nesheim ME, Hibbard LS, Mann KG. Isolation of functional human coagulation factor V by using a hybridoma antibody. Proc Natl Acad Sci USA 1981, 78:162-6.
26. Lundblad RL, Kingdon HS, Mann KG. Thrombin. Methods Enzymol 1976, 45:156-76.
27. Higgins DL, Mann KG. The interaction of bovine factor V and factor V-derived peptides with phospholipid vesicles. J Biol Chem 1983, 258:6503-8.
28. Butenas S, DiLorenzo ME, Mann KG. Ultrasensitive fluorogenic substrates for serine proteases. Thromb Haemost 1997, 78:1193-201.
29. Edman P. A method for the determination of amino acid sequence in peptides. Arch Biochem 1949, 22:475-6.
30. Hockin MF, Jones KC, Everse SJ, Mann KG. A model for the stoichiometric regulation of blood coagulation. J Biol Chem 2002, 277:18322-33.
31. Sun Y, Gailani D. Identification of a factor IX binding site on the third apple domain of activated factor XI. J Biol Chem 1996, 271:29023-8.
32. Sinha D, Seaman FS, Walsh PN. Role of calcium ions and the heavy chain of factor XIa in the activation of human coagulation factor IX. Biochemistry 1987, 26:3768-75.
33. Pedicord DL, Seiffert D, Blat Y. Substrate-dependent modulation of the mechanism of factor XIa inhibition. Biochemistry 2004, 43:11883-8.
34. Orfeo T, Brufatto N, Nesheim ME, Xu H, Butenas S, Mann KG. The factor V activation paradox. J Biol Chem 2004, 279:19580-91.
35. Soons H, Janssen-Claessen T, Tans G, Hemker HC. Inhibition of factor XIa by antithrombin III. Biochemistry 1987, 26:4624-9.
36. Butenas S, Parhami-Seren B, Mann KG. The influence of von Willebrand factor on factor VIII activity measurements. J Thromb Haemost 2009, 7:132-7.
37. Fay PJ, Haidaris PJ, Smudzin TM. Human factor VIIIa subunit structure. Reconstruction of factor VIIIa from the isolated A1/A3-C1-C2 dimer and A2 subunit. J Biol Chem 1991, 266:8957-62.
38. Lollar P, Parker CG. pH-dependent denaturation of thrombin-activated porcine factor VIII. J Biol Chem 1990, 265:1688-92.
39. Tracy PB, Eide LL, Bowie EJ, Mann KG. Radioimmunoassay of factor V in human plasma and platelets. Blood 1982, 60:59-63.
40. Mann KG, Nesheim ME, Tracy PB. Molecular weight of undegraded plasma factor V. Biochemistry 1981, 20:28-33.
41. Nesheim ME, Foster WB, Hewick R, Mann KG. Characterization of Factor V activation intermediates. J Biol Chem 1984, 259:3187-96.
42. Krishnaswamy S, Russell GD, Mann KG. The reassociation of factor Va from its isolated subunits. J Biol Chem 1989, 264:3160-8.
43. Odegaard B, Mann K. Proteolysis of factor Va by factor Xa and activated protein C. J Biol Chem 1987, 262:11233-8.
44. Lollar P, Knutson GJ, Fass DN. Activation of porcine factor VIII: by thrombin and factor Xa. Biochemistry 1985, 24:8056-64.
45. Ratnoff OD, Colopy JE. A familial hemorrhagic trait associated with a deficiency of a clot-promoting fraction of plasma. J Clin Invest 1955, 34:602-13.
46. Kleinschnitz C, Stoll G, Bendszus M, Schuh K, Pauer HU, Burfeind P, Renne C, Gailani D, Nieswandt B, Renne T. Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis. J Exp Med 2006, 203:513-18.
47. Castaman G, Ruggeri M, Rodeghiero F. A new Italian family with severe prekallikrein deficiency. Desmopressin-induced fibrinolysis and coagulation changes in homozygous and heterozygous members. Ric Clin Lab 1990, 20:239-44.
48. Cheung PP, Kunapuli SP, Scott CF, Wachtfogel YT, Colman RW. Genetic basis of total kininogen deficiency in Williams' trait. J Biol Chem 1993, 268:23361-5.
49. Rapaport SI, Proctor RR, Patch MJ, Yettra M. The mode of inheritance of PTA deficiency: evidence for the existence of major PTA deficiency and minor PTA deficiency. Blood 1961, 18:149-65.
50. Leiba H, Ramot B, Many A. Heredity and coagulation studies in ten families with Factor XI (plasma thromboplastin antecedent) deficiency. Br J Haematol 1965, 11:654-65.
51. Asakai R, Chung DW, Davie EW, Seligsohn U. Factor XI deficiency in Ashkenazi Jews in Israel. N Engl J Med 1991, 325:153-8.
52. Meijers JC, Davie EW, Chung DW. Expression of human blood coagulation factor XI: characterization of the defect in factor XI type III deficiency. Blood 1992, 79:1435-40.
53. Butenas S, Dee JD, Mann KG. The function of factor XI in tissue factor-initiated thrombin generation. J Thromb Haemost 2003, 1:2103-11.
54. Cawthern KM, van't Veer C, Lock JB, DiLorenzo ME, Branda RF, Mann KG. Blood coagulation in hemophilia A and hemophilia C. Blood 1998, 91:4581-92.
55. Butenas S, Undas A, Gissel MT, Szuldrzynski K, Zmudka K, Mann KG. Factor XIa and tissue factor activity in patients with coronary artery disease. Thromb Haemost 2008, 99:142-9.
56. Cushman M, O'Meara ES, Folsom AR, Heckbert SR. Coagulation factors IX through XIII and the risk of future venous thrombosis: the Longitudinal Investigation of Thromboembolism Etiology. Blood 2009, 114:2878-83.