Flat adenoma in colon: Two decades of debate

Journal of Digestive Diseases

Volumn 11, Issue 4, 2010, Pages 201-207

  Lau, Patrick CP ^a   Sung, Joseph JY ^b  

^a Department of Clinical Oncology ^*  (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Adenoma; Depressed; Flat; Non polypoid; Polyps.

Indexed keywords

CARCINOGENESIS; COLON ADENOMA; COLON POLYP; COLONOSCOPY; COLORECTAL CARCINOMA; COMPUTED TOMOGRAPHIC COLONOGRAPHY; GENE MUTATION; HUMAN; NARROW BAND IMAGING; ONCOGENE K RAS; POLYPECTOMY; PRIORITY JOURNAL; REVIEW; TUMOR SUPPRESSOR GENE; ADENOMA; COLONIC NEOPLASMS; COLONIC POLYPS; GENETICS; PATHOLOGY; RECTAL NEOPLASMS;

ADENOMA; COLONIC NEOPLASMS; COLONIC POLYPS; COLONOSCOPY; HUMANS; RECTAL NEOPLASMS;

EID: 77955032341     PISSN: 17512972     EISSN: 17512980     Source Type: Journal    
DOI: 10.1111/j.1751-2980.2010.00439.x     Document Type: Review

References (50)

1. Muto T, Bussey H, Morson B. The evoluation of cancer of the colon and rectum. Cancer 1975, 36:2251-70.
2. Winewer SJ, Zanher AG, Ho MN. Prevention of colorectal cancer by colonoscopic polypectomy. N Engl J Med 1993, 329:1977-81.
3. Muto T, Kamiya J, Sawada T. Small 'flat adenoma' of the large bowel with special reference to its clinicopathologic features. Dis Colon Rectum 1985, 28:847-51.
4. Kudo S, Kashida H, Tamura S, Nakajima T. The problem of flat colonic adenoma. Gastrointest Endosc Clin N Am 1997, 7:87-98.
5. General rules for clinical and pathological studies on cancer of the colon, rectum and anus. Part I. Clinical classification. Jpn J Surg 1983, 13:557-73. Japanese Research Society for Cancer of the Colon and Rectum
6. Diebold MD, Samalin E, Merle C. Colonic flat neoplasia: frequency and concordance between endoscopic appearance and histological diagnosis in a French prospective series. Am J Gastroenterol 2004, 99:1795-800.
7. Matsui T, Yao T, Iwashita A. Natural history of early colorectal cancer. World J Surg 2000, 24:1022-8.
8. Soetikno R, Friedland S, Kaltenbach T, Chayama K, Tanaka S. Nonpolypoid (flat and depressed) colorectal neoplasms. Gastroenterology 2006, 130:566-76.
9. Lynch HT, Smyrk T, Lanspa SJ. Flat adenomas in a colon cancer-prone kindred. J Natl Cancer Inst 1988, 80:278-82.
10. Jaramillo E, Watanabe M, Slezak P, Rubio C. Flat neoplastic lesions of the colon and rectum detected by high-resolution video endoscopy and chromoscopy. Gastrointest Endosc 1995, 42:114-22.
11. Fujii T, Rembacken BJ, Dixon ME, Yoshida S, Axon AT. Flat adenomas in the United Kingdom: are treatable cancers being missed? Endoscopy 1998, 30:437-43.
12. Rembacken BJ, Fujii T, Cairns A. Flat and depressed colonic neoplasms: a prospective study of 1000 colonoscopies in the UK. Lancet 2000, 8(355):1211-14.
13. Saitoh Y, Waxman I, West AB. Prevalence and distinctive biologic features of flat colorectal adenomas in a North American population. Gastroenterology 2001, 120:1657-65.
14. Wong KS, Chua WC, Cheong DM, Sim R, Yap WM. Flat colorectal lesions: colonoscopic detection without dye spray or magnification and clinical significance. Asian J Surg 2004, 27:299-302.
15. Rajendra S, Kutty K, Karim N. Flat colonic adenomas in Malaysia: fact or fancy? J Gastroenterol Hepatol 2003, 18:701-4.
16. Huang PC, Shieh MJ, Liang JT, Chang KJ, Shun CT. Flat adenoma of the colon: 2 cases. J Formos Med Assoc 1997, 96:649-52.
17. Hart AR, Kudo S, Mackay EH, Mayberry JF, Atkin WS. Flat adenomas exist in asymptomatic people: important implications for colorectal cancer screening programmes. Gut 1998, 43:229-31.
18. Waye J, O'Brien M. Cancer in polyps. Cancer of the colon, rectum, and anus 1995, 465-76. Cohen MA, Winawer S. eds., New York, McGraw-Hill
19. Wolber RA, Owen DA. Flat adenomas of the colon. Human Pathol 1991, 21:70-74.
20. O'Brien MJ, Winawer SJ, Zauber AG. National Polyp Study Workgroup. Flat adenomas in the national polyp study: is there increased risk for high-grade dysplasia initially or during surveillance? Clin Gastroenterol Hepatol 2004, 2:905-11.
21. Tsuda S, Veress B, Tóth E, Fork FT. Flat and depressed colorectal tumours in a southern Swedish population: a prospective chromoendoscopic and histopathological study. Gut 2002, 51:550-55.
22. Schlemper RJ, Itabashi M, Kato Y. Differences in the diagnostic criteria for gastric carcinoma between Japanese and western pathologists. Lancet 1997, 349:1725-9.
23. Schlemper RJ, Itabashi M, Kato Y. Differences in the diagnostic criteria used by Japanese and western pathologists to diagnose colorectal carcinoma. Cancer 1998, 82:60-69.
24. Schlemper RJ, Riddell R, Kato Y. The Vienna classification of gastrointestinal epithelial neoplasia. Gut 2000, 47:251-5.
25. Higashidani Y, Tamura S, Morita T. Analysis of K-ras codon 12 mutation in flat and nodular variants of serrated adenoma in the colon. Dis Colon Rectum 2003, 46:327-32.
26. Minamoto T, Sawaguchi K, Mai M, Yamashita N, Sugimura T, Esumi H. Infrequent K-ras activation in superficial-type (flat) colorectal adenomas and adenocarcinomas. Cancer Res 1994, 54:2841-4.
27. Yashiro M, Carethers JM, Laghi L. Genetic pathways in the evolution of morphologically distinct colorectal neoplasms. Cancer Res 2001, 61:2676-83.
28. Morita T, Tomita N, Ohue M. Molecular analysis of diminutive, flat, depressed colorectal lesions: are they precursors of polypoid adenoma or early stage carcinoma? Gastrointest Endosc 2002, 56:663-71.
29. Rubio CA, Rodensjo M. Mutation of p53 tumor suppressor gene in flat neoplastic lesions of the colorectal mucosa. Dis Colon Rectum 1996, 39:143-7.
30. Kinney T, Merel N, Hart J, Joseph L, Waxman I. Microsatellite analysis of sporadic flat and depressed lesions of the colon. Dig Dis Sci 2005, 50:327-30.
31. Bartkova J, Thullberg M, Slezak P. Aberrant expression of G1-phase cell cycle regulators in flat and exophytic adenomas of the human colon. Gastroenterology 2001, 120:1680-88.
32. Minami R, Aoyama N, Honsako Y, Kasuga M, Fujimori T, Maeda S. Codon 201 Arg/Gly polymorphism of DCC (deleted in colorectal cancer) gene in flat-and polypoid-type colorectal tumors. Dig Dis Sci 1997, 42:2446-52.
33. Ajioka Y, Watanabe H, Kazama S. Early colorectal cancer with special reference to the superficial nonpolypoid type from a histopathologic point of view. World J Surg 2000, 24:1075-80.
34. Kudo S, Muto T. Superficial depressed type (IIc) of colorectal carcinoma. Gastroenterol Endosc 1986, 28:2811-13.
35. Kudo S, Tamura S, Hirota Y. The problem of de novo colorectal carcinoma. Eur J Cancer 1995, 31A:1118-20.
36. Nasir A, Boulward D, Kaiser HF. Flat and polypoid adenocarcinomas of the colorectum: a comparative histomorphologic analysis of 47 cases. Hum Pathol 2004, 35:604-11.
37. Shimoda T, Ikegami M, Fujisaki J, Matsui T, Aizawa S, Ishikawa E. Early colorectal carcinoma with special reference to its development de novo. Cancer 1989, 64:1138-46.
38. Mueller J, Bethke B, Stolte M. Colorectal de novo carcinoma: a review of its diagnosis, histopathology, molecular biology, and clinical relevance. Virchows Arch 2002, 440:453-60.
39. Kiesslich R, Von Bergh M, Hahn M, Hermann G, Jung M. Chromoendoscopy with indigocarmine improves the detection of adenomatous and nonadenomatous lesions in the colon. Endoscopy 2001, 33:1001-6.
40. Mitooka H, Fujimori T, Maeda S, Nagasako K. Minute flat depressed neoplastic lesions of the colon detected by contrast chromoscopy using an indigo carmine capsule. Gastrointest Endosc 1995, 41:453-9.
41. Kudo S, Hirota S, Nakajima T. Colorectal tumors and pit pattern. J Clin Pathol 1994, 47:880-85.
42. Brooker J, Saunders B, Shah S. Total colonic dye-spray increases the detection of diminutive adenomas during routine colonoscopy: a randomized controlled trial. Gastrointest Endosc 2002, 56:333-8.
43. Kara M, Peters F, Rosmolen W. High-resolution endoscopy plus chromoendoscopy or narrow-band imaging in Barrett's esophagus: a prospective randomized crossover study. Endoscopy 2005, 37:929-36.
44. Machida H, Sano Y, Hamamoto Y. Narrow-band imaging in the diagnosis of colorectal mucosal lesions: a pilot study. Endoscopy 2004, 36:1094-8.
45. Park SH, Ha HK, Kim MJ. False-negative results at multi-detector row CT colonography: multivariate analysis of causes for missed lesions. Radiology 2005, 235:495-502.
46. Pickhardt PJ, Nugent PA, Choi JR, Schindler WR. Flat colorectal lesions in asymptomatic adults: implications for screening with CT virtual colonoscopy. Am J Roentgenol 2004, 183:1343-7.
47. Kudo S, Tamegai Y, Yamano H, Imai Y, Kogure E, Kashida H. Endoscopic mucosal resection of the colon: the Japanese technique. Gastrointest Endosc Clin N Am 2001, 11:519-35.
48. Su MY, Hsu CM, Ho YP. Endoscopic mucosal resection for colonic non-polypoid neoplasms. Am J Gastroenterol 2005, 100:2174-9.
49. Conio M, Repici A, Demarquay JF, Blanchi S, Demas R, Filiberti R. EMR of large sessile colorectal polyps. Gastrointest Endosc 2004, 60:234-41.
50. Hurlstone DP, Cross SS, Brown B, Sanders DS, Lobo AJ. A prospective evaluation of high-magnification chromoscopic colonoscopy in predicting completeness of EMR. Gastrointest Endosc 2004, 59:642-50.