Cancer in nonagenarians: Profile, treatments and outcomes

Critical Reviews in Oncology/Hematology

Volumn 75, Issue 2, 2010, Pages 160-164

  Extermann, Martine ^a,b   Crane, Edward J ^c   Boulware, David ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^c Oncology Hematology Care   (United States)

Author keywords

Cancer; Chemo radiation therapy; Chemotherapy; Nonagenarians; Radiation therapy; Second cancers; Surgery; Survival; Treatment tolerance

Indexed keywords

ANTINEOPLASTIC AGENT; ARSENIC TRIOXIDE; BLEOMYCIN; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; CYTARABINE; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; FOLINIC ACID; MITOXANTRONE; NAVELBINE; PACLITAXEL; PREDNISONE; RETINOIC ACID; TOPOTECAN; TRASTUZUMAB; VINCRISTINE; VINCRISTINE SULFATE;

ACUTE GRANULOCYTIC LEUKEMIA; ADVANCED CANCER; AGED; ALTERNATIVE MEDICINE; BLADDER CANCER; CANCER CHEMOTHERAPY; CANCER HORMONE THERAPY; CANCER MORTALITY; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CHRONIC LYMPHATIC LEUKEMIA; CONGESTIVE HEART FAILURE; DRUG DOSE REDUCTION; ELDERLY CARE; FEMALE; FRAIL ELDERLY; HOSPICE CARE; HUMAN; INFECTION; LIP CARCINOMA; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; PATIENT CARE; PHOTODYNAMIC THERAPY; PNEUMONIA; RECTUM CANCER; REVIEW; SECOND CANCER; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE; SURVIVAL TIME; TREATMENT RESPONSE; COMORBIDITY; MORTALITY; MULTIMODALITY CANCER THERAPY; NEOPLASMS; PROGNOSIS; REGISTER; SICKNESS IMPACT PROFILE; SURVIVAL; TREATMENT OUTCOME; VERY ELDERLY;

AGED, 80 AND OVER; COMBINED MODALITY THERAPY; COMORBIDITY; FEMALE; HUMANS; MALE; NEOPLASMS; PROGNOSIS; REGISTRIES; SICKNESS IMPACT PROFILE; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 77955021449     PISSN: 10408428     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2010.06.011     Document Type: Review

References (16)

1. Andersen S.L., Terry D.F., Wilcox M.A., et al. Cancer in the oldest old. Mech Ageing Dev 2005, 126:263-267.
2. Zeber J.E., Copeland L.A., Hosek B.J., et al. Cancer rates, medical comorbidities, and treatment modalities in the oldest patients. Crit Rev Oncol Hematol 2008, 67:237-242.
3. Bouchardy C., Rapiti E., Fioretta G., et al. Undertreatment strongly decreases prognosis of breast cancer in elderly women. J Clin Oncol 2003, 21:3580-3587.
4. Evron E., Goldberg H., Kuzmin A., et al. Breast cancer in octogenarians. Cancer 2006, 106:1664-1668.
5. Zachariah B., Balducci L., Venkattaramanabalaji G.V., et al. Radiotherapy for cancer patients aged 80 and older: a study of effectiveness and side effects. Int J Radiat Oncol Biol Phys 1997, 39:1125-1129.
6. Cloven N.G., Manetta A., Berman M.L., et al. Management of ovarian cancer in patients older than 80 years of Age. Gynecol Oncol 1999, 73:137-139.
7. Bairey O., Benjamini O., Blickstein D., et al. Non-Hodgkin's lymphoma in patients 80 years of age or older. Ann Oncol 2006, 17:928-934.
8. Hesketh P.J., Lilenbaum R.C., Chansky K., et al. Chemotherapy in patients > or =80 with advanced non-small cell lung cancer: combined results from SWOG 0027 and LUN 6. J Thorac Oncol 2007, 2:494-498.
9. Kawashima M., Kagami Y., Toita T., et al. Prospective trial of radiotherapy for patients 80 years of age or older with squamous cell carcinoma of the thoracic esophagus. Int J Radiat Oncol Biol Phys 2006, 64:1112-1121.
10. Ruol A., Portale G., Castoro C., et al. Management of esophageal cancer in patients aged over 80 years. Eur J Cardiothorac Surg 2007, 32:445-448.
11. Extermann M., Overcash J., Lyman G.H., et al. Comorbidity and functional status are independent in older cancer patients. J Clin Oncol 1998, 16:1582-1587.
12. Corcoran M.E. Polypharmacy in the older patient with cancer. Cancer Control 1997, 4:419-428.
13. Saltzstein S.L., Behling C.A. 5- and 10-year survival in cancer patients aged 90 and older: a study of 37, 318 patients from SEER. J Surg Oncol 2002, 81:113-116. (dicussion 117).
14. Extermann M., Boler I., Blair J., et al. Prevalence of multiple cancers in Floridian patients aged 70 years and older. Crit Rev Oncol Hematol 2006, 60:S27.
15. Adkins R.B., Scott H.W. Surgical procedures in patients aged 90 years and older. South Med J 1984, 77:1357-1364.
16. Konttinen N., Rosenberg P.H. Outcome after anaesthesia and emergency surgery in patients over 100 years old. Acta Anaesthesiol Scand 2006, 50:283-289.