Radiotherapy for cancer patients aged 80 and older: A study of effectiveness and side effects

International Journal of Radiation Oncology Biology Physics

Volumn 39, Issue 5, 1997, Pages 1125-1129

  Zachariah, Babu ^b   Balducci, Lodovico ^a   Venkattaramanabalaji, G V ^b   Casey, Linda ^b   Greenberg, Harvey M ^a   DelRegato, Juan A ^b  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Cancer; Elderly; Oldest old; Radiotherapy

Indexed keywords

AGED; AGING; ARTICLE; BONE MARROW SUPPRESSION; BREAST CARCINOMA; CANCER CONTROL; CANCER LOCALIZATION; CANCER RADIOTHERAPY; DIARRHEA; DYSPHAGIA; ENTERITIS; FEMALE; HEAD AND NECK CARCINOMA; HUMAN; LUNG CARCINOMA; MAJOR CLINICAL STUDY; MALE; MUCOSA INFLAMMATION; PELVIS TUMOR; PRIORITY JOURNAL; RADIATION DOSE; RADIATION INJURY; WEIGHT REDUCTION;

AGED; AGED, 80 AND OVER; FEMALE; HUMANS; MALE; NEOPLASMS; PATIENT COMPLIANCE; RADIOTHERAPY; RETROSPECTIVE STUDIES;

EID: 0030659062     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(97)00552-X     Document Type: Article

References (25)

1. Balducci, L.; Lyman, G. H. Adjuvant treatment of cancer in the older person. In: Balducci, L.; Lyman, G. H.; Ershler, W. B., eds. Geriatric oncology. Philadelphia: J. B. Lippincott; 1992:284-302.
2. Balducci, L.; Mowrey, K.; Parker, M. Pharmacology of anti-neoplastic agents in older patients. In: Balducci, L.; Lyman, G. H.; Ershler, W. B., eds. Geriatric oncology. Philadelphia: J. B. Lippincott; 1992:169-180.
3. Bardoh, T.; Isoyama, T.; Toyoshima, H. Total gastrectomy for gastric cancer in the elderly. Surgery 109:136-142; 1991.
4. Beghe', C.; Balducci, L. Geriatric Oncology: Perspectives from decision analysis. Arch. Gerontol. Geriatr. 10:141-162; 1990.
5. Chin, R.; Fisher, R. J.; Smee, R. I.; Barton, M. B. Oropharyngeal cancer in the elderly. Int. J. Radiat. Oncol. Biol. Phys. 32:1007-1016; 1995.
6. Cowan, H. J.; Bartolucci, A. Age and the treatment of multiple myeloma. Southeastern Cancer Group experience. Am J. Med. 79:316-324; 1985.
7. Donegan, W. L. Operative treatment of cancer in the older person by general surgeon. In: Balducci, L.; Lyman, G. H.; Ershler, W. B., eds. Geriatric oncology. Philadelphia J. B. Lippincott; 1992:151-159.
8. Fentiman, L. S.; Tirelli, U.; Monfardini, S.; Schneider, M.; Festen, J.; Cognetti, F.; Aapro, M. S. Cancer in the elderly: Why so badly treated. Lancet 335:1020-1022; 1990.
9. Forman, J. D.; Order, S. E.; Zinreich, E. S.; Lee, D. J.; Wharam, M. D. Carcinoma of the prostate in the elderly. The therapeutic ratio of definitive radiation therapy. J. Urol. 136: 1238-1241; 1990.
10. Grant, P. T.; Jeffrey, J. F.; Fraser, R. C.; Tompkins, M. G.; Filbee, J. F.; Wong, O. S. Pelvic radiation therapy for gynecologic malignancies in geriatric patients. Gynecol Oncol. 33:185-188; 1989.
11. Greenberg, H. M.; Trotti, A. M. Radiotherapy of cancer in the older person. In: Balducci, L.; Lyman, G. H.; Ershler, W. B., eds. Geriatric oncology. Philadelphia: J. B. Lippincott: 1992: 160-168.
12. Hishikawa, Y.; Kurisu, K.; Taniguchi, M.; Kamikonya, N.; Miura, T. Radiotherapy for carcinoma of the esophagus in patients aged 80 and older. Int. J. Radiat. Oncol. Biol. Phys. 20:685-688; 1991.
13. Kantorowitz, D. A.; Poulter, C. A.; Sischy, B.; Paterson, E.; Sobel, S. H.; Rubin, P.; Dvoretsky, P. A.; Mishalak, W.; Doane, K. L. Treatment of breast cancer among elderly women with segmental mastectomy or segmental mastectomy plus postoperative radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 15:263-270; 1988.
14. Karnofsky, D. A.; Burchenal, J. L. The clinical evaluation of chemotherapeutic agents in cancer: In: Macleod, C. M., ed. Evaluation of chemotherapeutic agents. New York: Columbia University Press; 1949:199-205.
15. Levrant, S. G.; Fruchter, F. G.; Malman, M. Radical hysterectomy for cervical cancer: Morbidity and survival in relation to weight and age. Gynecol. Oncol. 45:317-322; 1992.
16. Lusinchi, A.; Bourhis, J.; Wibault, P.; Le Ridant, A. M.; Eschwege, F. Radiation therapy for head and neck cancer in the elderly. Int. J. Radiat. Oncol. Biol. Phys. 18:819-823; 1990.
17. Monfardini, S.; Yancik, R. M. Cancer and aging. Meeting the challenges of an aging population. J. Natl. Cancer Inst. 85: 532-539; 1993.
18. Mor, V.; Masterson-Allen, S.; Goldberg, R. J.; Cummings, F. J.; Glicksman, A. S.; Fretwell, M. D. Relationship between age at diagnosis and treatment received by cancer patients. J. Am. Geriatr. Soc. 33:585-589; 1985.
19. Noordijk, E. M.; Clement, E. V. D.; Hermans, J.; Wever, A. M. J. Leer, J. W. H. Radiotherapy as an alternative to surgery in elderly patinets with resectable lung cancer. Radiother. Oncol. 13:83-89; 1988.
20. Scalliet, P. Radiotherapy in the elderly. Eur. J. Cancer 27:3; 1991.
21. Schilcher, B.; Curschmann, J. Clinical results of radiotherapy in 140 elderly patients treated at basel university hospital between 1980 and 1985. Int. J. Radiat. Oncol. Biol. Phys. 33:774; 1995.
22. Swanson, R. S.; Sawicka, J.; Wood, W. C. Treatment of carcinoma of the breast in the older geriatric patient. Surg. Gynecol. Obstet. 173:465-469; 1991.
23. Yansic, R.; Gloeckler, R. L.; Yates, D. W. Ovarian cancer in the elderly: An analysis of surveillance, epidemiology, and end results program data. Am. J. Obstet. Gynecol. 154:639-646; 1986.
24. Zachariah, B.; Casey, L.; Balducci, L. Radiotherapy of the oldest old cancer patients: A study of effectiveness and toxicity. J. Am. Geriatr. Soc. 43:793-795; 1995.
25. Zietman, A. L.; Linggood, R. M.; Brookes, A. R.; Convery, K.; Piro, A. Radiation therapy in the management of early stage hodgkins disease presenting in later life. Cancer 68: 1869-1873; 1991.