Soluble epithin/PRSS14 secreted from cancer cells contains active angiogenic potential

Molecules and Cells

Volumn 29, Issue 6, 2010, Pages 617-623

  Kim, Sang Bum ^a,d   Lee, Deokjae ^e   Jeong, Joo Won ^b   Kim, Chungho ^c   Park, Dongeun ^a   Kim, Moon Gyo ^e  

^a Seoul National University   (South Korea)

^b Kyung Hee University Hospital   (South Korea)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF TEXAS AT DALLAS   (United States)

^e Inha University   (South Korea)

Author keywords

angiogenesis; epithin; hypoxia; matriptase; PRSS14

Indexed keywords

MEMBRANE PROTEIN; PROTEIN EPITHIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CANCER CELL; CELL DIFFERENTIATION; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN SECRETION; THYMOMA; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION;

ANGIOGENESIS INDUCING AGENTS; ANIMALS; ANTIBODIES, MONOCLONAL; BLOOD VESSELS; CARCINOMA; CATTLE; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CHICKENS; CHORIOALLANTOIC MEMBRANE; DISEASE PROGRESSION; ENDOTHELIAL CELLS; HUMANS; MELANOMA, EXPERIMENTAL; MICE; MORPHOGENESIS; NEOPLASM METASTASIS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; NIH 3T3 CELLS; RNA, SMALL INTERFERING; SERINE ENDOPEPTIDASES; TRANSGENES;

BOVINAE;

EID: 77955020372     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10059-010-0077-0     Document Type: Article

References (31)

1. N.I. Affara P. Andreu L.M. Coussens 2009 Delineating protease functions during cancer development Methods Mol. Biol. 539 1 32 10.1007/978-1-60327-003-8- 1 1:CAS:528:DC%2BD1MXlvF2qu74%3D 19377975
2. R.T. Aimes A. Zijlstra J.D. Hooper S.M. Ogbourne M.L. Sit S. Fuchs D.C. Gotley J.P. Quigley T.M. Antalis 2003 Endothelial cell serine proteases expressed during vascular morphogenesis and angiogenesis Thromb. Haemost. 89 561 572 1:CAS:528:DC%2BD3sXitlSktbg%3D 12624642
3. L. Basel-Vanagaite R. Attia A. Ishida-Yamamoto L. Rainshtein D. Ben Amitai R. Lurie M. Pasmanik-Chor M. Indelman A. Zvulunov S. Saban 2007 Autosomal recessive ichthyosis with hypotrichosis caused by a mutation in ST14, encoding type II transmembrane serine protease matriptase Am. J. Hum. Genet 80 467 477 10.1086/512487 1:CAS:528:DC%2BD2sXit1Wksr4%3D 17273967
4. E.G. Cho M.G. Kim C. Kim S.R. Kim I.S. Seong C. Chung R.H. Schwartz D. Park 2001 N-terminal processing is essential for release of epithin, a mouse type II membrane serine protease J. Biol. Chem. 276 44581 44589 10.1074/jbc.M107059200 1:CAS:528:DC%2BD3MXovFegtrg%3D 11567025
5. E.G. Cho R.H. Schwartz M.G. Kim 2005 Shedding of membrane epithin is blocked without LDLRA4 and its protease activation site Biochem. Biophys. Res. Commun. 327 328 334 10.1016/j.bbrc.2004.12.014 1:CAS:528:DC%2BD2MXksFKk 15629466 (Pubitemid 40051388)
6. N. Ferrara R.S. Kerbel 2005 Angiogenesis as a therapeutic target Nature 438 967 974 10.1038/nature04483 1:CAS:528:DC%2BD2MXhtlSksrnI 16355214 (Pubitemid 43093963)
7. C.H. Ha Z.G. Jin 2009 Protein kinase D1, a new molecular player in VEGF signaling and angiogenesis Mol. Cells 28 1 5 10.1007/s10059-009-0109-9 1:CAS:528:DC%2BD1MXhtVCgu7jM 19655095
8. X. Jin M. Yagi N. Akiyama T. Hirosaki S. Higashi C.Y. Lin R.B. Dickson H. Kitamura K. Miyazaki 2006 Matriptase activates stromelysin (MMP-3) and promotes tumor growth and angiogenesis Cancer Sci. 97 1327 1334 10.1111/j.1349-7006. 2006.00328.x 1:CAS:528:DC%2BD28Xht1OgurrI 16999819 (Pubitemid 44614984)
9. J.Y. Kang M. Dolled-Filhart I.T. Ocal B. Singh C.Y. Lin R.B. Dickson D.L. Rimm R.L. Camp 2003 Tissue microarray analysis of hepatocyte growth factor/Met pathway components reveals a role for Met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of nodenegative breast cancer Cancer Res. 63 1101 1105 1:CAS:528:DC%2BD3sXhs1agtLw%3D 12615728
10. C. Kim Y. Cho C.H. Kang M.G. Kim H. Lee E.G. Cho D. Park 2005 Filamin is essential for shedding of the transmembrane serine protease, epithin EMBO Rep. 6 1045 1051 10.1038/sj.embor.7400534 1:CAS:528:DC%2BD2MXhtFKlsLrF 16170303 (Pubitemid 41637649)
11. M.G. Kim C. Chen M.S. Lyu E.G. Cho D. Park C. Kozak R.H. Schwartz 1999 Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains Immunogenetics 49 420 428 10.1007/s002510050515 1:CAS:528:DyaK1MXitVKmtrw%3D 10199918 (Pubitemid 29178825)
12. S.L. Lee R.B. Dickson C.Y. Lin 2000 Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease J. Biol. Chem. 275 36720 36725 10.1074/jbc.M007802200 1:CAS:528:DC%2BD3cXoslWmu7g%3D 10962009 (Pubitemid 32002078)
13. C.Y. Lin J. Anders M. Johnson Q.A. Sang R.B. Dickson 1999 Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity J. Biol. Chem. 274 18231 18236 10.1074/jbc.274.26.18231 1:CAS:528:DyaK1MXktF2qsrs%3D 10373424 (Pubitemid 29293809)
14. C.Y. Lin I.C. Tseng F.P. Chou S.F. Su Y.W. Chen M.D. Johnson R.B. Dickson 2008 Zymogen activation, inhibition, and ectodomain shedding of matriptase Front Biosci. 13 621 635 10.2741/2707 1:CAS:528:DC%2BD1cXhs1Cht7w%3D 17981575 (Pubitemid 351599772)
15. K. List 2009 Matriptase: a culprit in cancer Future Oncol. 5 97 104 10.2217/14796694.5.1.97 1:CAS:528:DC%2BD1MXitlyltb0%3D 19243302
16. K. List R. Szabo A. Molinolo V. Sriuranpong V. Redeye T. Murdock B. Burke B.S. Nielsen J.S. Gutkind T.H. Bugge 2005 Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation Genes Dev. 19 1934 1950 10.1101/gad.1300705 1:CAS:528: DC%2BD2MXpsFCqs74%3D 16103220 (Pubitemid 41186993)
17. K. List T.H. Bugge R. Szabo 2006 Matriptase: potent proteolysis on the cell surface Mol. Med. 12 1 7 10.2119/2006-00022.List 1:CAS:528: DC%2BD28Xos1yqtLs%3D 16838070
18. M.M. Mohamed B.F. Sloane 2006 Cysteine cathepsins: multifunctional enzymes in cancer Nat. Rev. Cancer 6 764 775 10.1038/nrc1949 1:CAS:528:DC%2BD28XpvVCmu7Y%3D 16990854 (Pubitemid 44450465)
19. T. Mosmann 1983 Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays J. Immunol. Methods 5 55 63 10.1016/0022-1759(83)90303-4
20. S. Netzel-Arnett J.D. Hooper R. Szabo E.L. Madison J.P. Quigley T.H. Bugge T.M. Antalis 2003 Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer Cancer Metastasis Rev. 22 237 258 10.1023/A:1023003616848 1:CAS:528: DC%2BD3sXis1CjtL0%3D 12784999 (Pubitemid 36561060)
21. M.D. Oberst M.D. Johnson R.B. Dickson C.Y. Lin B. Singh M. Stewart A. Williams A. al-Nafussi J.F. Smyth H. Gabra 2002 Expression of the serine protease matriptase and its inhibitor HAI-1 in epithelial ovarian cancer: correlation with clinical outcome and tumor clinicopathological parameters Clin. Cancer Res. 8 1101 1107 1:CAS:528:DC%2BD38XjsF2ltrk%3D 11948120
22. C.M. Overall O. Kleifeld 2006 Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy Nat. Rev. Cancer 6 227 239 10.1038/nrc1821 1:CAS:528: DC%2BD28Xhslelt70%3D 16498445 (Pubitemid 43292566)
23. M.T. Park H.J. Cha J.W. Jeong S.I. Kim H.Y. Chung N.D. Kim O.H. Kim K.W. Kim 1999 Glucocorticoid receptor-induced down-regulation of MMP-9 by ginseng components, PD and PT contributes to inhibition of the invasive capacity of HT1080 human fibrosarcoma cells Mol. Cells 9 476 483 1:CAS:528: DyaK1MXntlOls7c%3D 10597035
24. R. Roy B. Zhang M.A. Moses 2006 Making the cut: protease-mediated regulation of angiogenesis Exp. Cell Res. 312 608 622 10.1016/j.yexcr.2005.11. 022 1:CAS:528:DC%2BD28XhvVWltbc%3D 16442099 (Pubitemid 43290337)
25. M. Saleem V.M. Adhami W. Zhong B.J. Longley C.Y. Lin R.B. Dickson S. Reagan-Shaw D.F. Jarrard H. Mukhtar 2006 A novel biomarker for staging human prostate adenocarcinoma: overexpression of matriptase with concomitant loss of its inhibitor, hepatocyte growth factor activator inhibitor-1 Cancer Epidemiol. Biomarkers Prev. 15 217 227 10.1158/1055-9965.EPI-05-0737 1:CAS:528: DC%2BD28Xhs1WrsL8%3D 16492908 (Pubitemid 43342167)
26. M. Seiki I. Yana 2003 Roles of pericellular proteolysis by membrane type-1 matrix metalloproteinase in cancer invasion and angiogenesis Cancer Sci. 94 569 574 10.1111/j.1349-7006.2003.tb01484.x 1:CAS:528:DC%2BD2cXhs1Kgs7k%3D 12841863 (Pubitemid 36975009)
27. R. Szabo J.P. Hobson K. Christoph P. Kosa K. List T.H. Bugge 2009 Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice Development 136 2653 2663 10.1242/dev.038430 1:CAS:528:DC%2BD1MXhtVGhtbbI 19592578
28. T. Takeuchi M.A. Shuman C.S. Craik 1999 Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue Proc. Natl. Acad. Sci. USA 96 11054 11061 10.1073/pnas.96.20.11054 1:CAS:528:DyaK1MXmvVCntb4%3D 10500122 (Pubitemid 29487326)
29. T. Takeuchi J.L. Harris W. Huang K.W. Yan S.R. Coughlin C.S. Craik 2000 Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates J. Biol. Chem. 275 26333 26342 10.1074/jbc.M002941200 1:CAS:528:DC%2BD3cXmt1Okt74%3D 10831593
30. K. Uhland 2006 Matriptase and its putative role in cancer Cell. Mol. Life Sci. 63 2968 2978 10.1007/s00018-006-6298-x 1:CAS:528:DC%2BD2sXht1egtbk%3D 17131055 (Pubitemid 46072302)
31. Q. Wu 2003 Type II transmembrane serine proteases Curr. Top Dev. Biol. 54 167 206 10.1016/S0070-2153(03)54009-1 1:CAS:528:DC%2BD3sXjslygtbY%3D 12696750 (Pubitemid 137639469)