Diabetes-related defects in sarcoplasmic Ca 2+ release are prevented by inactivation of Gα 11 and Gα q in murine cardiomyocytes

Molecular and Cellular Biochemistry

Volumn 341, Issue 1-2, 2010, Pages 235-244

  Hoyer, Dieter Paul ^a   Grönke, Sabine ^a   Frank, Konrad F ^a   Addicks, Klaus ^a   Wettschureck, Nina ^b   Offermanns, Stefan ^b   Erdmann, Erland ^a   Reuter, Hannes ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Annexin A7; Knockout mice; Ryanodine receptor; Sorcin; Type 1 diabetes

Indexed keywords

CALCIUM ION; FK 506 BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; RYANODINE RECEPTOR 2; SORCIN; SYNEXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; ECHOCARDIOGRAPHY; GENE EXPRESSION; HEART FUNCTION; HEART LEFT VENTRICLE ENDDIASTOLIC DIAMETER; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE SIZE; MEMBRANE VESICLE; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; WESTERN BLOTTING; WILD TYPE;

ANIMALS; ANNEXIN A7; CALCIUM; CARDIOMEGALY; DIABETES COMPLICATIONS; DIABETES MELLITUS, EXPERIMENTAL; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HEART DISEASES; MICE; MICE, KNOCKOUT; MYOCYTES, CARDIAC; PROTEINS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; TACROLIMUS BINDING PROTEINS;

ANIMALIA; MURINAE; MUS;

EID: 77955013224     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0454-1     Document Type: Article

References (35)

1. TW Riggs D Transue 1990 Doppler echocardiographic evaluation of left ventricular diastolic function in adolescents with diabetes mellitus Am J Cardiol 65 899 902 10.1016/0002-9149(90)91433-7 1:STN:280:DyaK3c3gvFyruw%3D%3D 2321540 (Pubitemid 20114527)
2. ZA Lababidi DE Goldstein 1983 High prevalence of echocardiographic abnormalities in diabetic youths Diabetes Care 6 18 22 10.2337/diacare.6.1.18 1:STN:280:DyaL3s7otF2lsA%3D%3D 6220877
3. DD Belke WH Dillmann 2004 Altered cardiac calcium handling in diabetes Curr Hypertens Rep 6 424 429 10.1007/s11906-004-0035-3 15527685
4. H Reuter S Gronke C Adam M Ribati J Brabender C Zobel KF Frank J Wippermann RH Schwinger K Brixius J Muller-Ehmsen 2008 Sarcoplasmic Ca(2+) release is prolonged in nonfailing myocardium of diabetic patients Mol Cell Biochem 308 141 149 10.1007/s11010-007-9622-3 1:CAS:528:DC%2BD1cXhtFWqt7g%3D 17952561 (Pubitemid 351167855)
5. Y Teshima N Takahashi T Saikawa M Hara S Yasunaga S Hidaka T Sakata 2000 Diminished expression of sarcoplasmic reticulum Ca(2+)-ATPase and ryanodine sensitive Ca(2+)Channel mRNA in streptozotocin-induced diabetic rat heart J Mol Cell Cardiol 32 655 664 10.1006/jmcc.2000.1107 1:CAS:528:DC%2BD3cXit12hsr0%3D 10756121 (Pubitemid 30658934)
6. EF Farrell A Antaramian A Rueda AM Gomez HH Valdivia 2003 Sorcin inhibits calcium release and modulates excitation-contraction coupling in the heart J Biol Chem 278 34660 34666 10.1074/jbc.M305931200 1:CAS:528:DC%2BD3sXmvVCqtLk%3D 12824171 (Pubitemid 37553315)
7. C Herr N Smyth S Ullrich F Yun P Sasse J Hescheler B Fleischmann K Lasek K Brixius RH Schwinger R Fassler R Schroder AA Noegel 2001 Loss of annexin A7 leads to alterations in frequency-induced shortening of isolated murine cardiomyocytes Mol Cell Biol 21 4119 4128 10.1128/MCB.21.13.4119-4128.2001 1:CAS:528:DC%2BD3MXksVOrtr8%3D 11390641 (Pubitemid 32565294)
8. XH Wehrens SE Lehnart AR Marks 2005 Intracellular calcium release and cardiac disease Annu Rev Physiol 67 69 98 10.1146/annurev.physiol.67.040403. 114521 1:CAS:528:DC%2BD2MXjsFelu7w%3D 15709953 (Pubitemid 40404486)
9. SO Marx S Reiken Y Hisamatsu T Jayaraman D Burkhoff N Rosemblit AR Marks 2000 PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts Cell 101 365 376 10.1016/S0092-8674(00)80847-8 1:CAS:528:DC%2BD3cXjsFekurY%3D 10830164
10. N Yaras M Ugur S Ozdemir H Gurdal N Purali A Lacampagne G Vassort B Turan 2005 Effects of diabetes on ryanodine receptor Ca release channel (RyR2) and Ca2+ homeostasis in rat heart Diabetes 54 3082 3088 10.2337/diabetes.54.11.3082 1:CAS:528:DC%2BD2MXht1Siu7bO 16249429 (Pubitemid 43334359)
11. J Suarez DD Belke B Gloss T Dieterle PM McDonough YK Kim LL Brunton WH Dillmann 2004 In vivo adenoviral transfer of sorcin reverses cardiac contractile abnormalities of diabetic cardiomyopathy Am J Physiol Heart Circ Physiol 286 H68 H75 10.1152/ajpheart.00245.2003 1:CAS:528:DC%2BD2cXotF2rsA%3D%3D 12958030
12. KR Bidasee K Nallani Y Yu RR Cocklin Y Zhang M Wang UD Dincer HR Besch Jr 2003 Chronic diabetes increases advanced glycation end products on cardiac ryanodine receptors/calcium-release channels Diabetes 52 1825 1836 10.2337/diabetes.52.7.1825 1:CAS:528:DC%2BD3sXltlWhuro%3D 12829653
13. NS Dhalla X Liu V Panagia N Takeda 1998 Subcellular remodeling and heart dysfunction in chronic diabetes Cardiovasc Res 40 239 247 10.1016/S0008-6363(98) 00186-2 1:CAS:528:DyaK1cXnsFKksro%3D 9893715 (Pubitemid 28506032)
14. H Reuter C Adam S Gronke C Zobel KF Frank J Muller-Ehmsen J Brabender RH Schwinger 2006 The increased angiotensin II (type 1) receptor density in myocardium of type 2 diabetic patients is prevented by blockade of the renin-angiotensin system Diabetologia 49 3067 3074 10.1007/s00125-006-0444-8 1:CAS:528:DC%2BD28XhtFylt7bF 17051401 (Pubitemid 44730311)
15. D Koya GL King 1998 Protein kinase C activation and the development of diabetic complications Diabetes 47 859 866 10.2337/diabetes.47.6.859 1:CAS:528:DyaK1cXjsFSgtrw%3D 9604860 (Pubitemid 28255657)
16. DT Eurich SR Majumdar RT Tsuyuki JA Johnson 2004 Reduced mortality associated with the use of ACE inhibitors in patients with type 2 diabetes Diabetes Care 27 1330 1334 10.2337/diacare.27.6.1330 1:CAS:528: DC%2BD2cXlt1yltbg%3D 15161784 (Pubitemid 38679979)
17. LH Lindholm H Ibsen B Dahlof RB Devereux G Beevers U de Faire F Fyhrquist S Julius SE Kjeldsen K Kristiansson O Lederballe-Pedersen MS Nieminen P Omvik S Oparil H Wedel P Aurup J Edelman S Snapinn 2002 Cardiovascular morbidity and mortality in patients with diabetes in the losartan intervention for endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol Lancet 359 1004 1010 10.1016/S0140-6736(02)08090-X 1:CAS:528: DC%2BD38XisV2htr0%3D 11937179 (Pubitemid 34286537)
18. S Ozdemir M Ugur H Gurdal B Turan 2005 Treatment with AT(1) receptor blocker restores diabetes-induced alterations in intracellular Ca(2+) transients and contractile function of rat myocardium Arch Biochem Biophys 435 166 174 10.1016/j.abb.2004.11.027 1:CAS:528:DC%2BD2MXos1GrsA%3D%3D 15680918 (Pubitemid 40170027)
19. G Wolkart X Pang H Stessel M Kirchengast F Brunner 2007 Chronic endothelin-A receptor antagonism is as protective as angiotensin converting enzyme inhibition against cardiac dysfunction in diabetic rats Br J Pharmacol 151 1187 1197 10.1038/sj.bjp.0707325 1:STN:280:DC%2BD2svnvVGjug%3D%3D 17572700 (Pubitemid 47255896)
20. S Offermanns LP Zhao A Gohla I Sarosi MI Simon TM Wilkie 1998 Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice EMBO J 17 4304 4312 10.1093/emboj/17.15.4304 1:CAS:528:DyaK1cXlsFOltLo%3D 9687499 (Pubitemid 28362621)
21. N Wettschureck H Rutten A Zywietz D Gehring TM Wilkie J Chen KR Chien S Offermanns 2001 Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Galphaq/Galpha11 in cardiomyocytes Nat Med 7 1236 1240 10.1038/nm1101-1236 1:CAS:528:DC%2BD3MXotlKks74%3D 11689889 (Pubitemid 33063779)
22. P Chomczynski N Sacchi 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal Biochem 162 156 159 10.1016/0003-2697(87)90021-2 1:CAS:528:DyaL2sXitFSns7Y%3D 2440339
23. CA Heid J Stevens KJ Livak PM Williams 1996 Real time quantitative PCR Genome Res 6 986 994 10.1101/gr.6.10.986 1:CAS:528:DyaK28XmsVWru7w%3D 8908518
24. 2+, adenine nucleotide, and calmodulin J Biol Chem 262 3065 3073 1:CAS:528:DyaL2sXhsFWksLs%3D 2434495
25. M Meyer W Schillinger B Pieske C Holubarsch C Heilmann H Posival G Kuwajima K Mikoshiba H Just G Hasenfuss, et al. 1995 Alterations of sarcoplasmic reticulum proteins in failing human dilated cardiomyopathy Circulation 92 778 784 1:CAS:528:DyaK2MXnsFGlsLk%3D 7641356
26. MM Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254 10.1016/0003-2697(76)90527-3 1:CAS:528: DyaE28XksVehtrY%3D 942051
27. W Luo IL Grupp J Harrer S Ponniah G Grupp JJ Duffy T Doetschman EG Kranias 1994 Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation Circ Res 75 401 409 1:CAS:528:DyaK2cXmsFWlu70%3D 8062415
28. KR Bidasee K Nallani HR Besch Jr UD Dincer 2003 Streptozotocin-induced diabetes increases disulfide bond formation on cardiac ryanodine receptor (RyR2) J Pharmacol Exp Ther 305 989 998 10.1124/jpet.102.046201 1:CAS:528: DC%2BD3sXkt1Snsbo%3D 12606683 (Pubitemid 36617976)
29. AB Brillantes K Ondrias A Scott E Kobrinsky E Ondriasova MC Moschella T Jayaraman M Landers BE Ehrlich AR Marks 1994 Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein Cell 77 513 523 10.1016/0092-8674(94)90214-3 1:CAS:528:DyaK2cXktlWltLs%3D 7514503 (Pubitemid 24153992)
30. 2+ release channels (ryanodine receptors) Science 281 818 821 10.1126/science.281.5378.818 1:CAS:528:DyaK1cXlt1Sntb4%3D 9694652 (Pubitemid 28376041)
31. 2+ release in myocytes from streptozotocin-induced diabetic rats J Mol Cell Cardiol 42 234 246 10.1016/j.yjmcc.2006.08.018 1:CAS:528: DC%2BD2sXht1Cltg%3D%3D 17027851 (Pubitemid 44958613)
32. SE Lehnart C Terrenoire S Reiken XH Wehrens LS Song EJ Tillman S Mancarella J Coromilas WJ Lederer RS Kass AR Marks 2006 Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias Proc Natl Acad Sci USA 103 7906 7910 10.1073/pnas.0602133103 1:CAS:528: DC%2BD28XlsVGksbg%3D 16672364
33. M Stange L Xu D Balshaw N Yamaguchi G Meissner 2003 Characterization of recombinant skeletal muscle (Ser-2843) and cardiac muscle (Ser-2809) ryanodine receptor phosphorylation mutants J Biol Chem 278 51693 51702 10.1074/jbc.M310406200 1:CAS:528:DC%2BD3sXpslOgsLc%3D 14532276 (Pubitemid 38020415)
34. M Galderisi KM Anderson PW Wilson D Levy 1991 Echocardiographic evidence for the existence of a distinct diabetic cardiomyopathy (the Framingham Heart Study) Am J Cardiol 68 85 89 10.1016/0002-9149(91)90716-X 1:STN:280: DyaK3M3otFKqsw%3D%3D 2058564
35. 2+ response amplitude and duration Nature 386 855 858 10.1038/386855a0 1:CAS:528:DyaK2sXivVGhsL4%3D 9126747