Patterns of care and survival in a retrospective analysis of 1059 patients with glioblastoma multiforme treated between 2002 and 2007: A multicenter study by the central nervous system study group of Airo (Italian association of radiation oncology)

Neurosurgery

Volumn 67, Issue 2, 2010, Pages 446-458

  Scoccianti, Silvia ^a   Magrini, Stefano Maria ^b   Ricardi, Umberto ^c   Detti, Beatrice ^a   Buglione, Michela ^a   Sotti, Guido ^d   Krengli, Marco ^e   Maluta, Sergio ^f   Parisi, Salvatore ^g   Bertoni, Filippo ^h   Mantovani, Cristina ^c   Tombolini, Vincenzo ⁱ   De Renzis, Costantino ^j   Lioce, Marco ^k   Fatigante, Lucia ^l   Fusco, Vincenzo ^m   Muto, Paolo ⁿ   Berti, Franco ^d   Rubino, Giovanni ^o   Cipressi, Samantha ^a   Fariselli, Laura ^p   Lupattelli, Marco ^q   Santoni, Riccardo ^r   Pirtoli, Luigi ^o   Biti, Giampaolo ^a   more..

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

^e UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^f UNIVERSITY HOSPITAL OF VERONA   (Italy)

^g CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^h UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

ⁱ UNIVERSITY OF L'AQUILA   (Italy)

^j UNIVERSITY OF MESSINA   (Italy)

^k Radioterapia Oncologica   (Italy)

^l UNIVERSITY HOSPITAL OF PISA   (Italy)

^m REFERRAL CANCER CENTER OF BASILICATA   (Italy)

ⁿ Radioterapia   (Italy)

^o UNIVERSITY OF SIENA   (Italy)

^p DEPARTMENT OF NEUROSURGERY   (Italy)

^q UNIVERSITY OF PERUGIA   (Italy)

^r UNIVERSITY OF ROME TOR VERGATA   (Italy)

more..

Author keywords

Chemotherapy; Database; Glioblastoma; Patterns of care; Radiotherapy

Indexed keywords

ANTICONVULSIVE AGENT; BLEOMYCIN; CARMUSTINE; FOTEMUSTINE; LOMUSTINE; PROCARBAZINE; STEROID; TEMOZOLOMIDE; VINCRISTINE;

ADJUVANT THERAPY; ADULT; AGED; AMINOTRANSFERASE BLOOD LEVEL; ANEMIA; BLOOD TOXICITY; BONE MARROW SUPPRESSION; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER SURVIVAL; CENTRAL NERVOUS SYSTEM; CLINICAL PRACTICE; CLINICAL TRIAL; COMPUTER ASSISTED RADIOTHERAPY; CONGENITAL DYSERYTHROPOIETIC ANEMIA; CRANIOTOMY; DEEP VEIN THROMBOSIS; DRUG DOSE REDUCTION; DRUG INDUCED HEADACHE; DRUG WITHDRAWAL; FATIGUE; FEMALE; GLIOBLASTOMA; HEADACHE; HEALTH CARE ORGANIZATION; HOME CARE; HUMAN; ITALY; KARNOFSKY PERFORMANCE STATUS; LIVER TOXICITY; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MULTIPLE CYCLE TREATMENT; MULTIVARIATE ANALYSIS; NAUSEA; NEUROLOGIC DISEASE; NEUTROPENIA; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE IMAGING; ONCOLOGY; PATIENT CARE; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROGNOSIS; RETROSPECTIVE STUDY; REVIEW; SEIZURE; SIDE EFFECT; SURVIVAL RATE; THROMBOCYTOPENIA; TUMOR BIOPSY; VOMITING;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, ALKYLATING; BRAIN NEOPLASMS; COMBINED MODALITY THERAPY; DACARBAZINE; DATABASES, FACTUAL; FEMALE; GLIOBLASTOMA; HUMANS; ITALY; KAPLAN-MEIER ESTIMATE; KARNOFSKY PERFORMANCE STATUS; MALE; MIDDLE AGED; NEUROSURGICAL PROCEDURES; PATIENT CARE; RADIOTHERAPY; RETROSPECTIVE STUDIES; SALVAGE THERAPY; SURVIVAL ANALYSIS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 77955002912     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.NEU.0000371990.86656.E8     Document Type: Review

References (16)

1. Stupp R, Mason WP, van den Bent MJ, et al. European Organisation for Research and Treatment of Cancer Brain Tumor and Radiotherapy Groups; National Cancer Institute of Canada Clinical Trials Group. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;52(10):987-996.
2. Stupp R, Hegi ME, Mason WP, et al. European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups; National Cancer Institute of Canada Clinical Trials Group. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5 year analysis of the EORTC-NCIC trial. Lancet Oncol. 2009;10(5):459-466.
3. Magrini S, Ricardi U, Santoni R, et al. Patterns of practice and survival in a retrospective analysis of 1722 adult astrocytoma patients treated between 1985 and 2001 in 12 Italian radiation oncology centers. Int J Radiat Oncol Biol Phys. 2006;65(3):788-799.
4. Curran WJ Jr, Scott CB, Horton J, et al. Recursive partitioning analysis of prognostic factors in three Radiation Therapy Oncology Group malignant glioma trials. J Natl Cancer Inst. 1993;85(9):704-710.
5. Chang SM, Parney IF, Huang W, et al. Patterns of care for adults with newly diagnosed malignant glioma. JAMA. 2005;293(5):557-564. (Pubitemid 40171237)
6. Rosenthal MA, Drummond KJ, Dally M, et al. Management of glioma in Victoria (1998-2000): retrospective cohort study. Med J Aust. 2006;184(6):270-273.
7. Cher L, Rosenthal MA, Drummond KJ, et al. The use of chemotherapy in patients with gliomas: patterns of care in Victoria from 1998-2000. J Clin Neurosci. 2008;15(4):398-401.
8. Laws ER, Parney IF, Huang W, et al. Survival following surgery and prognostic factors for recently diagnosed malignant glioma: data from the Glioma Outcomes Project. J Neurosurgery. 2003;99(3):467-473.
9. Lowry JK, Snyder JJ, Lowry PW. Brain tumors in the elderly: recent trends in a Minnesota cohort study. Arch Neurol. 1998;55(7):922-928.
10. Barnholtz-Sloan JS, Williams VL, Maldonado JL, et al. Patterns of care and outcomes among elderly individuals with primary malignant astrocytoma. J Neurosurg. 2008;108(4):642-648.
11. Gorlia T, van den Bent MJ, Hegi ME, et al. Nomograms for predicting survival of patients with newly diagnosed glioblastoma: prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE.3. Lancet Oncol. 2008;9(1):29-38.
12. Lutterbach J, Bartelt S, Momm F, Becker G, Frommhold H, Ostertag C. Is older age associated with a worse prognosis due to different patterns of care? A longterm study of 1346 patients with glioblastomas or brain metastases. Cancer. 2005;103(6):1234-1244.
13. Brandes AA, Vastola F, Basso U, et al. A prospective study on glioblastoma in the elderly. Cancer. 2008;97(3):657-662.
14. Mukerji N, Rodrigues D, Hendry G, Dunlop PR, Warburton F, Kane PJ. Treating high grade gliomas in the elderly: the end of ageism? J Neurooncol. 2008;86(3):329-336.
15. Shaw EG. Nothing ventured, nothing gained: treatment of glioblastoma multiforme in the elderly. J Clin Oncol. 2004;22(9):1540-1541.
16. Hegi ME, Diserens AC, Gorlia T, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med. 2005;352(10):997-1003.