Llama heavy-chain antibody fragments efficiently remove toxic shock syndrome toxin 1 from plasma in vitro but not in experimental porcine septic shock

Shock

Volumn 34, Issue 2, 2010, Pages 125-132

  Brummelhuis, Walter J ^a   Joles, Jaap A ^a   Stam, Jord C ^b   Adams, Hendrik ^c   Goldschmeding, Roel ^a   Detmers, Frank J ^c   El Khattabi, Mohamed ^b   Maassen, Bram T ^c   Verrips, C Theo ^b   Braam, Branko ^a,d,e  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c Bio Affinity Company BV   (Netherlands)

^d UNIVERSITY OF ALBERTA HOSPITAL   (Canada)

^e UNIVERSITY OF ALBERTA   (Canada)

Author keywords

hemofiltration; Llama heavy chain antibody fragments; septic shock; toxic shock syndrome toxin

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN HEAVY CHAIN; LLAMA HEAVY CHAIN ANTIBODY; TOXIC SHOCK SYNDROME TOXIN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BACTERIAL TOXIN; ENTEROTOXIN; ENTEROTOXIN F, STAPHYLOCOCCAL; PEPTIDE FRAGMENT; SUPERANTIGEN;

ADSORPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CELL ADHESION; CELL COMPARTMENTALIZATION; CELL SURFACE; CONTINUOUS HEMOFILTRATION; CONTINUOUS INFUSION; CONTROLLED STUDY; CYTAPHERESIS; CYTOKINE PRODUCTION; DISEASE COURSE; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; RESUSCITATION; SEPTIC SHOCK; SURVIVAL RATE; SWINE; ANIMAL; CELL CULTURE; HEMOFILTRATION; IMMUNOLOGY; METABOLISM; MONONUCLEAR CELL; NEW WORLD CAMELID; PIG; PROCEDURES; SHOCK, SEPTIC;

ANIMALS; BACTERIAL TOXINS; CAMELIDS, NEW WORLD; CELLS, CULTURED; ENTEROTOXINS; FEMALE; HEMOFILTRATION; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; LEUKOCYTES, MONONUCLEAR; PEPTIDE FRAGMENTS; SHOCK, SEPTIC; SUPERANTIGENS; SUS SCROFA;

EID: 77954998434     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181cdc556     Document Type: Article

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