Uterus transplantation in the baboon: Methodology and long-term function after auto-transplantation

Human Reproduction

Volumn 25, Issue 8, 2010, Pages 1980-1987

  Enskog, A ^a,b   Johannesson, L ^a   Chai, D C ^c   Dahm Kahler P ^a   Marcickiewicz, J ^a   Nyachieo, A ^c   Mwenda, J M ^c   Brannstrom M ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c INSTITUTE OF PRIMATE RESEARCH   (Kenya)

Author keywords

baboon; infertility; transplantation; uterus

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY ANASTOMOSIS; ARTICLE; AUTOTRANSPLANTATION; BABOON; DISSECTION; END TO SIDE ANASTOMOSIS; FEMALE; INTERNAL ILIAC ARTERY; ISCHEMIA; LAPAROSCOPY; LAPAROTOMY; MICROSCOPY; NONHUMAN; OPERATION DURATION; ORGAN TRANSPLANTATION; OUTCOME ASSESSMENT; OVARIAN VEIN; PELVIS; SECOND LOOK SURGERY; SIDE TO SIDE ANASTOMOSIS; SURGICAL ANATOMY; SURGICAL TECHNIQUE; UTERINE ARTERY; UTERUS; UTERUS FUNCTION; UTERUS TRANSPLANTATION; VEIN ANASTOMOSIS;

ANIMALIA; PAPIO; PRIMATES;

EID: 77954998007     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/deq109     Document Type: Article

References (43)

1. Al-Inany H. Intrauterine adhesions. An update. Acta Obstet Gynecol Scand 2001;80:986-993.
2. Altchek A. Uterus transplantation. Mount Sinai J Med 2003;70:154-162.
3. Avison DL, DeFaria W, Tryphonopoulos P, Tekin A, Attia GR, Takahashi H, Jin Y, Palaois N, Pararas N, Carreno MR et al. Heterotopic uterus transplantation in a swine model. Transplantation 2009;88:465-469.
4. Baird DT, Webb R, Campbell BK, Harkness LM, Gosden RG. Long-term ovarian function in the sheep after ovariectomy and transplantation of autografts stored at-1968C. Endocrinology 1999;140:462-471.
5. Barzilai A, Paldi E, Gal D, Hampel N. Autotransplantation of the uterus and ovaries in dogs. Israel J Med Sci 1973;9:49-52.
6. Brännström M, Wranning CA. Uterus transplantation-where do we stand today and where should we go? Expert Opin Biol Ther 2007; 7:427-429.
7. Brännström M, Wranning CA, El-Akouri RR. Transplantation of the uterus. Mol Cell Endocrinol 2003;202:177-184.
8. Dahm-Kähler P, Wranning CA, Lundmark C, Enskog A, Mölne J, Marcickiewicz J, El-Akouri RR, McCracken J, Brännström M. Transplantation of the uterus in the sheep: methodology and early reperfusion events. J Obstet Gynaecol Res 2008;34:784-793.
9. Del Priore G, Schlatt S, Malanowska-Stega J. Uterus transplant technique in primates: 10 years's experience. Exp Clin Transplant 2008;6:87-94.
10. Devauchelle B, Badet L, Lengele B, Morelon E, Testelin S, Michallet M, D'Hauthuille C, Dubernard JM. First human face allograft: early report. Lancet 2006;368:203-209.
11. Donnez J, Dolmans MM, Demylle D, Jadoul P, Pirard C, Squifflet J, Martinez-Madrid B, van Langendonckt A. Livebirth after orthotopic transplantation of cryopreserved ovarian tissue. Lancet 2004; 364:1405-1410. (Pubitemid 39370715)
12. Dubernard JM, Owen E, Herzberg G, Lanzetta M, Martin X, Kapila H, Dawahra M, Hakim NS. Human hand allograft: report on first 6 months. Lancet 1999;353:1315-1320.
13. Eraslan S, Hamernik RJ, Hardy JD. Replantation of uterus and ovaries in dogs, with successful pregnancy. Archs Surg 1966;92:9-12.
14. Fageeh W, Raffa H, Jabbad H, Marzouki A. Transplantation of the human uterus. Int J Gynecol Obstet 2002;76:245-251.
15. Grimbizis GF, Camus M, Tarlatzis BC, Bontis JN, Devroey P. Clinical implications of uterine malformations and hysteroscopic treatment results. Hum Reprod Update 2001;7:161-174.
16. Groth K, Akouri R, Wranning CA, Mölne J, Brännström M. Rejection of allogenic uterus transplant in the mouse: time-dependent and site-specific infiltration of leukocyte subtypes. Hum Reprod 2009; 24:2746-2754.
17. Guerrier D, Mouchel T, Pasquier L, Pellerin I. The Mayer-Rokitansky- Küster-Hauser syndrome (congenital absence of the uterus and vagina)-phenotypic manifestations and genetic approaches. J Negat Results Biomed 2006;5:1-8.
18. Jiga LP, Lupu CM, Zoica BS, Ionac M. Experimental model of heterotopic uterus transplantation in the laboratory rat. Microsurgery 2003; 23:246-250. (Pubitemid 36835592)
19. Kwee A, Bots ML, Visser GH, Bruinse HW. Emergency peripartum hysterectomy: a prospective study in the Netherlands. Eur J Obstet Gynecol Reprod Biol 2006;124:187-192.
20. Milliez J. FIGO committee report: uterine transplantation. Int J Gynecol Obstet 2009;106:207.
21. Nakash H, Herdiman J. Surrogacy. J Obstet Gynaecol 2007;27:246-251.
22. Nyachieo A, Chai DC, Deprest J, Mwenda JM, D Hooghe TM. The baboonasa research model for the study of endometrial biology, uterine receptivity and embryo implantation. Gynecol Obstet Invest 2007;64:149-155.
23. Oliveira FG, Abdelmassih VG, Diamond MP, Dozortsev D, Melo NR, Abdelmassih R. Impact of subserosal and intramural fibroids that do not distort the endometrial cavity on the outcome of in vitro fertilization-intracytoplasmic sperm injection. Fertil Steril 2004; 81:582-587.
24. Paldi E, Gal D, Barzilai A, Hampel N, Malberger E. Genital organs. Auto-and homo-transplantation in forty dogs. Int J Fertil 1975;20:5-12.
25. Racho El-Akouri R, Kurlberg G, Dindelegan G, Mölne J, Wallin A, Brännström M. Heterotopic uterine transplantation by vascular anastomosis in the mouse. J Endocrinol 2002;174:157-166.
26. Racho El-Akouri R, Kurlberg G, Brännström M. Successful uterine transplantation in the mouse: pregnancy and post-natal development of offspring. Hum Reprod 2003;18:2018-2023.
27. Ramirez ER, Ramirez DK, Pillari VT, Vasquez H, Ramirez HA. Modified uterine transplant procedure in the sheep model. J Min Inv Surg 2008; 15:311-314.
28. Scott JR, Pitkin RM, Yannone ME. Transplantation of the primate uterus. Surg Gynecol Obstet 1971;133:414-418.
29. Sieunarine K, Zakaria FBP, Boyle DCM, Corless DJ, Noakes DE, Lindsay I, Lawson A, Ungar L, Del Priore G, Smith JR. Possibilities for fertility restoration: a new surgical technique. Int Surg 2005;90:249-256.
30. Silber SJ, Lenahan KM, Levine DJ, Pineda JA, Gorman KS, Friez MJ, Crawford EC, Gosden RG. Ovarian transplantation between monozygotic twins discordant for premature ovarian failure. N Engl J Med 2005;353:58-63.
31. Sonoda Y, Abu-Rustum NR, Gemignani ML, Chi DS, Brown CL, Poynor EA, Barakat RR. A fertility-sparing alternative to radical hysterectomy: how many patients may be eligible? Gynecol Oncol 2004;95:534-538.
32. Stevens VC. Some reproductive studies in the baboon. Hum Reprod Update 1997;3:533-540.
33. Wranning CA, El-Akouri R, Lundmark C, Dahm-Kähler P, Mölne J, Enskog A, Brännström M. Autotransplantation of the uterus in the domestic pig: surgical technique and early reperfusion events. J Obstet Gynaecol Res 2006;32:358-367.
34. Wranning CA, Akhi SN, Kurlberg G, Brännström M. Uterus transplantation in the rat: model development, surgical learning and morphological evaluation of healing. Acta Obstet Gynecol Scand 2008a; 87:1239-1247.
35. Wranning CA, Dahm-Kähler P, Mölne J, Nilsson UA, Enskog A, Brännström M. Transplantation of the uterus in the sheep: oxidative stress and reperfusion injury after short-time cold storage. Fertil Steril 2008b;90:817-826.
36. Wranning CA, Marcickiewicz J, Enskog A, Dahm-Kähler P, Hanafy A, Brännström M. Fertility after autologous ovine uterine-tubal-ovarian transplantation by vascular anastomosis to the external iliac vessels. Hum Reprod 2010; in press.
37. Zelinski-Wooten MB, Alexander M, Christensen CL, Wolf DP, Hess DL, Stouffer RL. Individualized gonadotropin regimens for follicular stimulation in macaques during in vitro fertilization (IVF) cycles. J Med Primatol 1994;23:367-374.
38. Almeida SA, Teofilo JM, Anselmo Franci JA, Brentegani LG, Lamano-Carvalho TL. Antireproductive effect of the calcium channel blocker amlodipine in male rats. Exp Toxicol Pathol 2000;52:353-356.
39. Aquila S, Guido C, Perrotta I, Tripepi S, Nastro A, Ando S. Human sperm anatomy: ultrastructural localization of 1alpha,25-dihydroxyvitamin D receptor and its possible role in the human male gamete. J Anat 2008;213:555-564.
40. Blomberg Jensen M, Nielsen JE, Jorgensen A, Rajpert-De Meyts E, Kristensen DM, Jorgensen N, Skakkebaek NE, Juul A, Leffers H. Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract. Hum Reprod 2010; 25:1303-1311.
41. Hong CY, Chiang BN, Turner P. Calcium ion is the key regulator of human sperm function. Lancet 1984;2:1449-1451.
42. Menegaz D, Rosso A, Royer C, Leite LD, Santos AR, Silva FR. Role of 1alpha,25(OH)2 vitamin D3 on alpha-[1-(14)C]MeAIB accumulation in immature rat testis. Steroids 2009;74:264-269.
43. Uhland AM, Kwiecinski GG, DeLuca HF. Normalization of serum calcium restores fertility in vitamin D-deficient male rats. J Nutr 1992; 122:1338-1344.