Uterus transplantation in the rat: Model development, surgical learning and morphological evaluation of healing

Acta Obstetricia et Gynecologica Scandinavica

Volumn 87, Issue 11, 2008, Pages 1239-1247

  Wranning, Caiza A ^a   Akhi, Shamina N ^a   Kurlberg, Göran ^a   Brännström, Mats ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Inflammation; Lewis rats; Neutrophilic granulocytes; Uterus transplantation

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GRAFT SURVIVAL; IMMUNOSUPPRESSIVE TREATMENT; MICROSURGERY; NEUTROPHIL; NONHUMAN; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; RAT; SURGICAL RISK; SURGICAL TRAINING; UTERUS; UTERUS FUNCTION;

ANIMALS; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; GRANULOCYTES; GYNECOLOGIC SURGICAL PROCEDURES; HUMANS; INFERTILITY, FEMALE; MODELS, ANIMAL; RATS; RATS, INBRED LEW; REGIONAL BLOOD FLOW; TIME FACTORS; TRANSPLANTATION, HOMOLOGOUS; UTERUS;

EID: 56649115579     PISSN: 00016349     EISSN: 16000412     Source Type: Journal    
DOI: 10.1080/00016340802484966     Document Type: Article

References (31)

1. Oppelt P, Renner SP, Kellermann A, Brucker S, Hauser GA, Ludwig KS, et al. Clinical aspects of Mayer-Rokitansky-Kuester-Hauser syndrome: recommendations for clinical diagnosis and staging. Hum Reprod. 2006;21(3):792-7.
2. Merrill RM. Hysterectomy surveillance in the United States, 1997 through 2005. Med Sci Monit. 2008;14(1):CR24-31.
3. Yu D, Wong YM, Cheong Y, Xia E, Li TC. Asherman syndrome - one century later. Fertil Steril. 2008;89(4):759-79.
4. Taylor E, Gomel V. The uterus and fertility. Fertil Steril. 2008;89(1):1-16.
5. Sieunarine K, Zakaria FB, Boyle DC, Corless DJ, Noakes DE, Lindsay I, et al. Possibilities for fertility restoration: a new surgical technique. Int Surg. 2005;90(5):249-56.
6. Nair A, Stega J, Smith JR, Del Priore G. Uterus transplant: evidence and ethics. Ann N Y Acad Sci. 2008;1127:83-91.
7. Cohen J, Jones HW. Worldwide legislation. In: Gardner DK, Weissman A, Howles CM, editors. Textbook of assisted reproductive techniques: laboratory and clinical perspectives, 1st edn. London: Martin Dunitz Ltd.; 2001. p. 731-51.
8. Lanzetta M, Pozzo M, Bottin A, Merletti R, Farina D. Reinnervation of motor units in intrinsic muscles of a transplanted hand. Neurosci Lett. 2005;373(2):138-43.
9. Devauchelle B, Badet L, Lengele B, Morelon E, Testelin S, Michallet M, et al. First human face allograft: early report. Lancet. 2006;368(9531):203-9.
10. Brannstrom M, Wranning CA. Uterus transplantation: where do we stand today and where should we go? Expert Opin Biol Ther. 2007;7(4):427-9.
11. Fageeh W, Raffa H, Jabbad H, Marzouki A. Transplantation of the human uterus. Int J Gynaecol Obstet. 2002;76(3):245-51.
12. Racho El-Akouri R, Kurlberg G, Dindelegan G, Molne J, Wallin A, Brannstrom M. Heterotopic uterine transplantation by vascular anastomosis in the mouse. J Endocrinol. 2002;174(2):157-66.
13. Racho El-Akouri R, Kurlberg G, Brannstrom M. Successful uterine transplantation in the mouse: pregnancy and postnatal development of offspring. Hum Reprod. 2003;18(10):2018-23.
14. Racho El-Akouri R, Wranning CA, Molne J, Kurlberg G, Brannstrom M. Pregnancy in transplanted mouse uterus after long-term cold ischaemic preservation. Hum Reprod. 2003;18(10):2024-30.
15. El-Akouri RR, Molne J, Groth K, Kurlberg G, Brannstrom M. Rejection patterns in allogeneic uterus transplantation in the mouse. Hum Reprod. 2006;21(2):436-42.
16. Wranning CA, El-Akouri RR, Groth K, Molne J, Parra AK, Brannstrom M. Rejection of the transplanted uterus is suppressed by cyclosporine A in a semi-allogeneic mouse model. Hum Reprod. 2007;22(2):372-9.
17. Vessie EL, Hirsch GM, Lee TD. Aortic allograft vasculopathy is mediated by CD8(+) T cells in Cyclosporin A immuno-suppressed mice. Transpl Immunol. 2005;15(1):35-44.
18. Fein A, Vechoropoulos M, Nebel L. Cyclosporin-induced embryotoxicity in mice. Biol Neonate. 1989;56(3):165-73.
19. Martins PN. Learning curve, surgical results and operative complications for kidney transplantation in mice. Microsurgery. 2006;26(8):590-3.
20. Siemionow M, Demir Y, Mukherjee A, Klimczak A. Development and maintenance of donor-specific chimerism in semi-allogenic and fully major histocompatibility complex mismatched facial allograft transplants. Transplantation. 2005;79(5):558-67.
21. Muramatsu K, Suzuki H, You-Xin S, Hashimoto T, Matsunaga T, Taguchi T. Donor cell repopulation of whole-limb allografts in the rat: detection with green fluorescent protein. Plast Reconstr Surg. 2007;120(1):100-7.
22. Wanzel KR, Hamstra SJ, Caminiti MF, Anastakis DJ, Grober ED, Reznick RK. Visual-spatial ability correlates with effi-ciency of hand motion and successful surgical performance. Surgery. 2003;134(5):750-7.
23. Ilie V, Ilie V, Ghetu N, Popescu S, Grosu O, Pieptu D. Assessment of the microsurgical skills: 30 minutes versus 2 weeks patency. Microsurgery. 2007;27(5):451-4.
24. Howard TK, Klintmalm GB, Cofer JB, Husberg BS, Goldstein RM, Gonwa TA. The influence of preservation injury on rejection in the hepatic transplant recipient. Transplantation. 1990;49(1):103-7.
25. Totsuka E, Fung JJ, Hakamada K, Ohashi M, Takahashi K, Nakai M, et al. Synergistic effect of cold and warm ischemia time on postoperative graft function and outcome in human liver transplantation. Transplant Proc. 2004;36(7):1955-8.
26. Schwarz A, Mengel M, Gwinner W, Radermacher J, Hiss M, Kreipe H, et al. Risk factors for chronic allograft nephropathy after renal transplantation: a protocol biopsy study. Kidney Int. 2005;67(1):341-8.
27. Vinten-Johansen J. Involvement of neutrophils in the pathogenesis of lethal myocardial reperfusion injury. Cardiovasc Res. 2004;61(3):481-97.
28. Wranning CA, Molne J, El-Akouri RR, Kurlberg G, Brannstrom M. Short-term ischaemic storage of human uterine myometrium - basic studies towards uterine transplantation. Hum Reprod. 2005;20(10):2736-44.
29. Tanaka M, Mokhtari GK, Terry RD, Gunawan F, Balsam LB, Hoyt G, et al. Prolonged cold ischemia in rat cardiac allografts promotes ischemia-reperfusion injury and the development of graft coronary artery disease in a linear fashion. J Heart Lung Transplant. 2005;24(11):1906-14.
30. Wehner S, Behrendt FF, Lyutenski BN, Lysson M, Bauer AJ, Hirner A, et al. Inhibition of macrophage function prevents intestinal inflammation and postoperative ileus in rodents. Gut. 2007;56(2):176-85.
31. Turler A, Moore BA, Pezzone MA, Overhaus M, Kalff JC, Bauer AJ. Colonic postoperative inflammatory ileus in the rat. Ann Surg. 2002;236(1):56-66.