The melanin synthesis inhibition and radical scavenging activities of compounds isolated from the aerial part of Lespedeza cyrtobotrya

Journal of Microbiology and Biotechnology

Volumn 20, Issue 6, 2010, Pages 988-994

  Lee, Mi Yeon ^a   Kim, Jin Hee ^a   Choi, Jung Nam ^a   Kim, Jiyoung ^a   Hwang, Geum Sook ^b   Lee, Choong Hwan ^a  

^a Konkuk University   (South Korea)

^b Korea Basic Science Institute (KBSI)   (South Korea)

Author keywords

Human melanoma (MNT 1) cell; Lespedeza cyrtobotrya; Radical scavenging; Tyrosinase

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2 (2,4 DIHYDROXYPHENYL) 6 HYDROXYBENZOFURAN; ASCORBIC ACID; DALBERGIOIDIN; ERIODICTYOL 7 O GLUCOPYRANOSIDE; HAGININ A; HERBACEOUS AGENT; KOJIC ACID; LESPEDEZA CYRTOBOTRYA EXTRACT; MELANIN; MONOPHENOL MONOOXYGENASE; UNCLASSIFIED DRUG; ENZYME INHIBITOR; PLANT EXTRACT; SCAVENGER;

ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; LESPEDEZA; LESPEDEZA CYRTOBOTRYA; MELANOGENESIS; MELANOMA CELL; AGARICALES; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL LINE; CHEMISTRY; ENZYMOLOGY; ISOLATION AND PURIFICATION; PLANT;

AGARICALES; CELL LINE; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; HUMANS; LESPEDEZA; MELANINS; MONOPHENOL MONOOXYGENASE; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS;

EID: 77954988787     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.0905.05054     Document Type: Article

References (28)

1. Abdel-Malek, Z. A., J. Knittel, A. L. Kadekaro, V. B. Swope, and R. Starrier. 2008. The melanocortin 1 receptor and the UV response of human melanocytes - a shift in paradigm. Photochem. Photobiol. 84: 501-508.
2. Baek, S. H., J. H. Kim, D. H. Kim, C. Y. Lee, J. Y. Kim, D. K. Chung, and C. H. Lee. 2008. Inhibitory effect of dalbergioidin isolated from the trunk of Lespedeza cyrtobotrya on melanin biosynthesis. J. Microbiol. Biotechnol. 18: 874-879.
3. Duncan, C. L. and E. M. Foster. 1968. Effect of sodium nitrite, sodium chloride, and sodium nitrate on germination and outgrowth of anaerobic spores. Appl. Microbiol. 16: 406-411.
4. Fitton, A. and K. L. Goa. 1991. Azelaic acid. A review of its pharmacological properties and therapeutic efficacy in acne and hyperpigmentary skin disorders. Drugs 41: 780-798.
5. Garrett, R. and C. Grisham. 2005. Biochemistry, pp. 421-432. 3rd Ed. Thomson Brooks/Cole, Belmont, CA.
6. Ha, Y. M., S. W. Chung, S. Song, H. Lee, H. Suh, and H. Y. Chung. 2007. 4-(6-Hydroxy-2-naphthyl)-1,3-bezendiol: A potent, new tyrosinase inhibitor. Biol. Pharm. Bull. 30: 1711-1715.
7. Kim, J. H., S. H. Baek, D. H. Kim, T. Y. Choi, T. J. Yoon, J. S. Hwang, M. R. Kim, H. J. Kwon, and C. H. Lee. 2008. Downregulation of melanin synthesis by haginin A and its application to in vivo lightening model. J. Invest. Dermatol. 128: 1227-1235.
8. Kim, Y. J. 2007. Antimelanogenic and antioxidant properties of gallic acid. Biol. Pharm. Bull. 30: 1052-1055.
9. Kubo, I., I. Kinst-Hori, S. K. Chaudhuri, Y. Kubo, Y. Sanchez, and T. Ogura. 2000. Flavonols from Heterotheca inuloides: Tyrosinase inhibitory activity and structural criteria. Bioorg. Med. Chem. 8: 1749-1755.
10. Lee, C. H., M. C. Chung, H. J. Lee, K. S. Bae, and Y. H. Kho. 1997. MR566A and MR566B, new melanin synthesis inhibitors produced by Trichoderma harzianum. I. Taxonomy, fermentation, isolation and biological activities. J. Antibiot. 50: 469-473.
11. Lee, Y. S., J. H. Park, M. H. Kim, S. H. Seo, and H. J. Kim. 2006. Synthesis of tyrosinase inhibitory kojic acid derivative. Arch. Pharm. 339: 111-114.
12. Maeda, K. and M. Fukuda. 1996. Arbutin: Mechanism of its depigmenting action in human melanocyte culture. J. Pharmacol. Exp. Ther. 276: 765-769.
13. 1Q. I. The structures of a new chalcone and two new isoflav-3-ens. Chem. Pharm. Bull. 28: 1172-1177.
14. 1Q. II. The structures of haginin C, haginin D and lespedol C. Chem. Pharm. Bull. 29: 2205-2209.
15. Mori-Hongo, M., H. Yamaguchi, T. Warashina, and T. Miyase. 2009. Melanin synthesis inhibitors from Lespedeza cyrtobotrya. J. Nat. Prod 72: 63-71.
16. Pan, J., S. Zhang, L. Yan, J. Tai, Q. Xiao, K. Zou, Y. Zhou, and J. Wu. 2008. Separation of flavanone enantiomers and flavanone glucoside diastereomers from Balanophora involucrata Hook. f. by capillary electrophoresis and reversed-phase high-performance liquid chromatography on a C18 column. J. Chromatogr. A 1185: 117-129.
17. Park, D. J. and J. C. Lee. 2008. A study on the antioxidative and depigmentation activities of the ethanol extract of Saururus herba. Kor. J. Herbology 23: 193-102.
18. Park, S. H., D. S. Kim, W. G. Kim, I. J. Ryoo, D. H. Lee, C. H. Huh, S. W. Youn, I. D. Yoo, and K. C. Park. 2004. Terrein: A new melanogenesis inhibitor and its mechanism. Cell Mol. Life Sci. 61: 2878-2885.
19. Parvez, S., M. Kang, H. S. Chung, C. Cho, M. C. Hong, M. K. Shin, and H. Bae. 2006. Survey and mechanism of skin depigmenting and lightening agents. Phytother. Res. 20: 921-934.
20. Parvez, S., M. Kang, H. S. Chung, and H. Bae. 2007. Naturally occurring tyrosinase inhibitors: Mechanism and applications in skin health, cosmetics and agriculture industries. Phytother. Res. 21: 805-816.
21. Perluigi, M., F. De Marco, C. Foppoli, R. Coccia, C. Blarzino, M. L. Marcante, and C. Cini. 2003. Tyrosinase protects human melanocytes from ROS-generating compounds. Biochem. Biophys. Res. Commun. 305: 250-256.
22. Prota, G. 1988. Progress in the chemistry of melanins and related metabolites. Med. Res. Rev. 8: 525-556.
23. Re, R., N. Pellegrini, A. Proteggente, A. Pannala, M. Yang, and C. Rice-Evans. 1999. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radio. Biol. Med. 26: 1231-1237.
24. Solano, F., S. Briganti, M. Picardo, and G. Ghanem. 2006. Hypopigmenting agents: An updated review on biological, chemical and clinical aspects. Pigment Cell Res. 19: 550-571.
25. Valverde, P., P. Manning, C. Todd, C. J. McNeil, and A. J. Thody. 1996. Tyrosinase may protect human melanocytes from the cytotoxic effects of the superoxide anion. Exp. Dermatol. 5: 247-253.
26. Vielhaber, G., G. Schmaus, K. Jacobs, H. Franke, S. Lange, M. Herrmann, H. Joppe, and O. Koch. 2007. 4-(1-Phenylethyl)1,3-benzenediol: A new, highly efficient lightening agent. Int. J. Cosmet. Sci. 29: 65-66.
27. Yasui, H. and H. Sakurai. 2003. Age-dependent generation of reactive oxygen species in the skin of live hairless rats exposed to UVA light. Exp. Dermatol. 12: 655-661.
28. Yoshida, T., K. Mori, T. Hatano, T. Okumura, I. Uehara, K. Komagoe, Y. Fujita and T. Okuda. 1989. Studies on inhibition mechanism of autoxidation by tannins and flavonoids. V. Radical-scavenging effects of tannins and related polyphenols on 1,1-diphenyl-2-picrylhydrzyl radical. Chem. Pharm. Bull. 37: 1919-1921.