Early administration of norepinephrine increases cardiac preload and cardiac output in septic patients with life-threatening hypotension

Critical Care

Volumn 14, Issue 4, 2010, Pages

  Hamzaoui, Olfa ^a   Georger, Jean François ^a   Monnet, Xavier ^a   Ksouri, Hatem ^a   Maizel, Julien ^a   Richard, Christian ^a   Teboul, Jean Louis ^a  

^a BICÊTRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

NORADRENALIN;

ADULT; ARTICLE; CARDIAC FUNCTION INDEX; DRUG EFFECT; FEMALE; GLOBAL END DIASTOLIC VOLUME INDEX; HEART INDEX; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FUNCTION; HEART OUTPUT; HEART PRELOAD; HEART STROKE VOLUME; HUMAN; HYPOTENSION; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; PERFUSION PRESSURE; PRIORITY JOURNAL; SEPTIC SHOCK; BLOOD PRESSURE; ELECTROCARDIOGRAPHY; INTENSIVE CARE; METHODOLOGY; MIDDLE AGED; PHYSIOLOGY; SEPSIS;

BLOOD PRESSURE; CARDIAC OUTPUT; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; HYPOTENSION; INTENSIVE CARE; MALE; MIDDLE AGED; NOREPINEPHRINE; SEPSIS; STROKE VOLUME;

EID: 77954968530     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc9207     Document Type: Article

References (29)

1. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med 2008, 34:17-60. 10.1007/s00134-007-0934-2, 2249616, 18058085.
2. Martin C, Papazian L, Perrin G, Saux P, Gouin F. Norepinephrine or dopamine for the treatment of hyperdynamic septic shock?. Chest 1993, 103:1826-1831. 10.1378/chest.103.6.1826, 8404107.
3. De Backer D, Biston P, Devriendt J, Madl C, Chochrad D, Aldecoa C, Brasseur A, Defrance P, Gottignies P, Vincent JL, . SOAP II Investigators Comparison of dopamine and norepinephrine in the treatment of shock. N Engl J Med 2010, 362:779-789. 10.1056/NEJMoa0907118, 20200382, SOAP II Investigators.
4. Datta P, Magder S. Hemodynamic response to norepinephrine with and without inhibition of nitric oxide synthase in porcine endotoxemia. Am J Respir Crit Care Med 1999, 160:1987-1993.
5. Desjars P, Pinaud M, Potel G, Tasseau F, Touze MD. A reappraisal of norepinephrine therapy in human septic shock. Crit Care Med 1987, 15:134-137. 10.1097/00003246-198702000-00011, 3802857.
6. Meadows D, Edwards JD, Wilkins RG, Nightingale P. Reversal of intractable septic shock with norepinephrine therapy. Crit Care Med 1988, 16:663-666. 10.1097/00003246-198807000-00003, 3371042.
7. Martin C, Viviand X, Arnaud S, Vialet R, Rougnon T. Effects of norepinephrine plus dobutamine or norepinephrine alone on left ventricular performance of septic shock patients. Crit Care Med 1999, 27:1708-1713. 10.1097/00003246-199909000-00002, 10507587.
8. Ledoux D, Astiz ME, Carpati CM, Rackow EC. Effects of perfusion pressure on tissue perfusion in septic shock. Crit Care Med 2000, 28:2729-2732. 10.1097/00003246-200008000-00007, 10966242.
9. Albanèse J, Leone M, Garnier F, Bourgoin A, Antonini F, Martin C. Renal effects of norepinephrine in septic and nonseptic patients. Chest 2004, 126:534-539. 10.1378/chest.126.2.534, 15302741.
10. Bourgoin A, Leone M, Delmas A, Garnier F, Albanèse J, Martin C. Increasing mean arterial pressure in patients with septic shock: effects on oxygen variables and renal function. Crit Care Med 2005, 33:780-786. 10.1097/01.CCM.0000157788.20591.23, 15818105.
11. Albanèse J, Leone M, Delmas A, Martin C. Terlipressine or norepinephrine in hyperdynamic septic shock: a prospective randomised study. Crit Care Med 2005, 33:1897-1902. 10.1097/01.CCM.0000178182.37639.D6, 16148457.
12. Deruddre S, Cheisson G, Mazoit JX, Vicaut E, Benhamou D, Duranteau J. Renal arterial resistance in septic shock: effects of increasing mean arterial pressure with norepinephrine on the renal resistive index assessed with Doppler ultrasonography. Intensive Care Med 2007, 33:1557-1562. 10.1007/s00134-007-0665-4, 17486316.
13. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M. Early Goal-Directed Therapy Collaborative Group: Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001, 345:1368-1377. 10.1056/NEJMoa010307, 11794169.
14. Pottecher T, Calvat S, Dupont H, Durand-Gasselin J, Gerbeaux P, . SFAR/SRLF workgroup Hemodynamic management of severe sepsis: recommendations of the French Intensive Care' Societies (SFAR/SRLF) Consensus Conference, 13 October 2005, Paris, France. Crit Care 2006, 10:311. 10.1186/cc4965, 1751016, 16941754, SFAR/SRLF workgroup.
15. Goedje O, Seebauer T, Peyerl M, Pfeiffer UJ, Reichart B. Hemodynamic monitoring by double-indicator dilution technique in patients after orthotopic heart transplantation. Chest 2000, 118:775-781. 10.1378/chest.118.3.775, 10988202.
16. Michard F, Alaya S, Zarka V, Bahloul M, Richard C, Teboul JL. Global end-diastolic volume as an indicator of cardiac preload in patients with septic shock. Chest 2003, 124:1900-1908. 10.1378/chest.124.5.1900, 14605066.
17. Combes A, Berneau JB, Luyt CE, Trouillet JL. Estimation of left ventricular systolic by single transpulmonary thermodilution. Intensive Care Med 2004, 30:1377-1383.
18. Ritter S, Rudiger A, Maggiorini M. Transpulmonary thermodilution-derived cardiac function index identifies cardiac dysfunction in acute heart failure and septic patients: an observational study. Crit Care 2009, 13:R133. 10.1186/cc7994, 2750191, 19671146.
19. Jabot J, Monnet X, Lamia B, Chemla D, Richard C, Teboul JL. Cardiac function index provided by transpulmonary thermodilution behaves as an indicator of left ventricular systolic function. Crit Care Med 2009, 37:2913-2918. 10.1097/CCM.0b013e3181b01fd9, 19866507.
20. Marik PE, Cavallazzi R, Vasu T, Hirani A. Dynamic changes in arterial waveform derived variables and fluid responsiveness in mechanically ventilated patients: a systematic review of the literature. Crit Care Med 2009, 37:2642-2647. 10.1097/CCM.0b013e3181a590da, 19602972.
21. Sennoun N, Montemont C, Gibot S, Lacolley P, Levy B. Comparative effects of early versus delayed use of norepinephrine in resuscitated endotoxic shock. Crit Care Med 2007, 35:1736-1740. 10.1097/01.CCM.0000269028.28521.08, 17522580.
22. Kozieras J, Thuemer O, Sakka SG. Influence of an acute increase in systemic vascular resistance on transpulmonary thermodilution-derived parameters in critically ill patients. Intensive Care Med 2007, 33:1619-1623. 10.1007/s00134-007-0669-0, 17522845.
23. McVeigh GE, Bratteli CW, Morgan DJ, Alinder CM, Glasser SP, Finkelstein SM, Cohn JN. Age related abnormalities in arterial compliance identified by pressure pulse contour analysis: aging and arterial compliance. Hypertension 1999, 33:1392-1398.
24. Martin C, Perrin G, Saux P, Papazian L, Gouin F. Effects of norepinephrine on right ventricular function in septic shock patients. Intensive Care Med 1994, 20:444-447. 10.1007/BF01710657, 7798451.
25. Silverman HJ, Peneranda R, Orens JB, Lee NH. Impaired beta-adrenergic receptor stimulation of cyclic adenosine monophosphate in human septic shock: association with myocardial hyporesponsiveness to catecholamines. Crit Care Med 1993, 21:31-39. 10.1097/00003246-199301000-00010, 8380553.
26. Scarpace PJ, Abrass IB. Desensitization of adenylate cyclase and down regulation of beta adrenergic receptors after in vivo administration of beta agonist. J Pharmacol Exp Ther 1982, 223:327-331.
27. Dubin A, Pozo MO, Casabella CA, Pálizas F, Murias G, Moseinco MC, Kanoore Edul VS, Pálizas F, Estenssoro E, Ince C. Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study. Crit Care 2009, 13:R92. 10.1186/cc7922, 2717464, 19534818.
28. Jhanji S, Stirling S, Patel N, Hinds CJ, Pearse RM. The effect of increasing doses of norepinephrine on tissue oxygenation and microvascular flow in patients with septic shock. Crit Care Med 2009, 37:1961-1966. 10.1097/CCM.0b013e3181a00a1c, 19384212.
29. Vieillard-Baron A, Caille V, Charron C, Belliard G, Page B, Jardin F. Actual incidence of global left ventricular hypokinesia in adult septic shock. Crit Care Med 2008, 36:1701-1706. 10.1097/CCM.0b013e318174db05, 18496368.