Relationship of intraoperative cerebral oxygen saturation to neurodevelopmental outcome and brain magnetic resonance imaging at 1 year of age in infants undergoing biventricular repair

Circulation

Volumn 122, Issue 3, 2010, Pages 245-254

  Kussman, Barry D ^a,e   Wypij, David ^b,f,h   Laussen, Peter C ^a,b,e   Soul, Janet S ^c   Bellinger, David C ^c   Dinardo, James A ^a,e   Robertson, Richard ^d,f   Pigula, Frank A ^a,g   Jonas, Richard A ^a,g   Newburger, Jane W ^b,f  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b Departments of Cardiology   (United States)

^c Boston University Medical Campus   (United States)

^d Radiology   (United States)

^e Departments of Anaesthesia   (United States)

^f Department of Pediatrics ^*  (United States)

^g HARVARD MEDICAL SCHOOL   (United States)

^h HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

brain; heart defects, congenital; magnetic resonance imaging; oxygen; spectroscopy, near infrared

Indexed keywords

HEMOSIDERIN;

AORTIC ARCH SURGERY; ARTICLE; BIVENTRICULAR REPAIR; BRAIN DEVELOPMENT; CARDIOPULMONARY BYPASS; CLINICAL TRIAL; FEMALE; HEAD CIRCUMFERENCE; HEART SURGERY; HUMAN; INFANT; INTRAOPERATIVE PERIOD; MAJOR CLINICAL STUDY; MALE; NEAR INFRARED SPECTROSCOPY; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN SATURATION; PRIORITY JOURNAL; RATING SCALE; WARMING;

BRAIN; CARDIOPULMONARY BYPASS; CEREBROVASCULAR CIRCULATION; CHILD DEVELOPMENT; DEVELOPMENTAL DISABILITIES; FEMALE; FOLLOW-UP STUDIES; HEART DEFECTS, CONGENITAL; HEMODILUTION; HEMOSIDERIN; HUMANS; HYPOTHERMIA, INDUCED; INFANT; INFANT, NEWBORN; LINEAR MODELS; MAGNETIC RESONANCE IMAGING; MALE; MONITORING, INTRAOPERATIVE; OXIMETRY; OXYGEN; PSYCHOMOTOR DISORDERS; SPECTROSCOPY, NEAR-INFRARED;

EID: 77954957188     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.109.902338     Document Type: Article

References (45)

1. Bellinger DC, Wypij D, du Plessis AJ, Rappaport LA, Jonas RA, Wer-novsky G, Newburger JW. Neurodevelopmental status at eight years in children with dextro-transposition of the great arteries: the Boston Circulatory Arrest Trial. J Thorac Cardiovasc Surg. 2003;126:1385-1396.
2. Mahle WT, Wernovsky G. Neurodevelopmental outcomes in hypoplastic left heart syndrome. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2004;7:39-47.
3. Newburger JW, Bellinger DC. Brain injury in congenital heart disease. Circulation. 2006;113:183-185.
4. Dent CL, Spaeth JP, Jones BV, Schwartz SM, Glauser TA, Hallinan B, Pearl JM, Khoury PR, Kurth CD. Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral per-fusion. J Thorac Cardiovasc Surg. 2005;130:1523-1530.
5. Goldberg CS, Bove EL, Devaney EJ, Mollen E, Schwartz E, Tindall S, Nowak C, Charpie J, Brown MB, Kulik TJ, Ohye RG. A randomized clinical trial of regional cerebral perfusion versus deep hypothermic circulatory arrest: outcomes for infants with functional single ventricle. J Thorac Cardiovasc Surg. 2007;133:880-887.
6. Hoffman GM, Mussatto KA, Brosig CL, Ghanayem NS, Musa N, Fedderly RT, Jaquiss RD, Tweddell JS. Systemic venous oxygen saturation after the Norwood procedure and childhood neurodevelopmental outcome. J Thorac Cardiovasc Surg. 2005;130:1094-1100.
7. Kinney HC, Panigrahy A, Newburger JW, Jonas RA, Sleeper LA. Hypoxic-ischemic brain injury in infants with congenital heart disease dying after cardiac surgery. Acta Neuropathol. 2005;110:563-578.
8. Mahle WT, Tavani F, Zimmerman RA, Nicolson SC, Galli KK, Gaynor JW, Clancy RR, Montenegro LM, Spray TL, Chiavacci RM, Wernovsky G, Kurth CD. An MRI study of neurological injury before and after congenital heart surgery. Circulation. 2002;106(suppl 1):I-109-I-114.
9. McQuillen PS, Barkovich AJ, Hamrick SE, Perez M, Ward P, Glidden DV, Azakie A, Karl T, Miller SP. Temporal and anatomic risk profile of brain injury with neonatal repair of congenital heart defects. Stroke. 2007;38:736-741.
10. Jobsis FF. Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. Science. 1977;198: 1264-1267.
11. Hagino I, Anttila V, Zurakowski D, Duebener LF, Lidov HG, Jonas RA. Tissue oxygenation index is a useful monitor of histologic and neurologic outcome after cardiopulmonary bypass in piglets. J Thorac Cardiovasc Surg. 2005;130:384-392.
12. Sakamoto T, Hatsuoka S, Stock UA, Duebener LF, Lidov HG, Holmes GL, Sperling JS, Munakata M, Laussen PC, Jonas RA. Prediction of safe duration of hypothermic circulatory arrest by near-infrared spectroscopy. J Thorac Cardiovasc Surg. 2001;122:339-350.
13. Austin EH III, Edmonds HL Jr, Auden SM, Seremet V, Niznik G, Sehic A, Sowell MK, Cheppo CD, Corlett KM. Benefit of neurophysiologic monitoring for pediatric cardiac surgery. J Thorac Cardiovasc Surg. 1997;114:707-715, 717.
14. Hoffman GM. Neurologic monitoring on cardiopulmonary bypass: what are we obligated to do? Ann Thorac Surg. 2006;81:S2373-S2380.
15. Kussman BD, Wypij D, DiNardo JA, Newburger JW, Mayer JE Jr, del Nido PJ, Bacha EA, Pigula F, McGrath E, Laussen PC. Cerebral oximetry during infant cardiac surgery: evaluation and relationship to early postoperative outcome. Anesth Analg. 2009;108:1122-1131.
16. Newburger JW, Jonas RA, Soul J, Kussman BD, Bellinger DC, Laussen PC, Robertson R, Mayer JE Jr, del Nido PJ, Bacha EA, Forbess JM, Pigula F, Roth SJ, Visconti KJ, du Plessis AJ, Farrell DM, McGrath E, Rappaport LA, Wypij D. Randomized trial of hematocrit 25% versus 35% during hypothermic cardiopulmonary bypass in infant heart surgery. J Thorac Cardiovasc Surg. 2008;135:347-354, e341-e344.
17. Kussman BD, Wypij D, DiNardo JA, Newburger J, Jonas RA, Bartlett J, McGrath E, Laussen PC. An evaluation of bilateral monitoring of cerebral oxygen saturation during pediatric cardiac surgery. Anesth Analg. 2005; 101:1294-1300.
18. Kurth CD, Levy WJ, McCann J. Near-infrared spectroscopy cerebral oxygen saturation thresholds for hypoxia-ischemia in piglets. J Cereb Blood Flow Metab. 2002;22:335-341.
19. Kurth CD, McCann JC, Wu J, Miles L, Loepke AW. Cerebral oxygen saturation-time threshold for hypoxic-ischemic injury in piglets. Anesth Analg. 2009;108:1268-1277.
20. Bayley N. Bayley Scales of Infant Development. 2nd ed. San Antonio, Tex: Psychological Corp; 1993.
21. Soul JS, Robertson RL, Wypij D, Bellinger DC, Visconti KJ, du Plessis AJ, Kussman BD, Scoppettuolo LA, Pigula F, Jonas RA, Newburger JW. Subtle hemorrhagic brain injury is associated with neurodevelopmental impairment in infants with repaired congenital heart disease. J Thorac Cardiovasc Surg. 2009;138:374-381.
22. Hollingshead AB. Four Factor Index of Social Status. New Haven, Conn: Yale University; 1975.
23. Ferrari M, Mottola L, Quaresima V. Principles, techniques, and limitations of near infrared spectroscopy. Can J Appl Physiol. 2004;29: 463-487.
24. Fenton KN, Freeman K, Glogowski K, Fogg S, Duncan KF. The significance of baseline cerebral oxygen saturation in children undergoing congenital heart surgery. Am J Surg. 2005;190:260-263.
25. Kurth CD, Steven JL, Montenegro LM, Watzman HM, Gaynor JW, Spray TL, Nicolson SC. Cerebral oxygen saturation before congenital heart surgery. Ann Thorac Surg. 2001;72:187-192.
26. Hanley FL. Religion, politics - deep hypothermic circulatory arrest. J Thorac Cardiovasc Surg. 2005;130:1236.
27. Ohye RG, Goldberg CS, Donohue J, Hirsch JC, Gaies M, Jacobs ML, Gurney JG. The quest to optimize neurodevelopmental outcomes in neonatal arch reconstruction: the perfusion techniques we use and why we believe in them. J Thorac Cardiovasc Surg. 2009;137:803-806.
28. Menache CC, du Plessis AJ, Wessel DL, Jonas RA, Newburger JW. Current incidence of acute neurologic complications after open-heart operations in children. Ann Thorac Surg. 2002;73:1752-1758.
29. Trittenwein G, Nardi A, Pansi H, Golej J, Burda G, Hermon M, Boigner H, Wollenek G. Early postoperative prediction of cerebral damage after pediatric cardiac surgery. Ann Thorac Surg. 2003;76:576-580.
30. Thavasothy M, Broadhead M, Elwell C, Peters M, Smith M. A comparison of cerebral oxygenation as measured by the NIRO 300 and the INVOS 5100 near-infrared spectrophotometers. Anaesthesia. 2002;57: 999-1006.
31. Dexter F, Hindman BJ. Theoretical analysis of cerebral venous blood hemoglobin oxygen saturation as an index of cerebral oxygenation during hypothermic cardiopulmonary bypass: a counterproposal to the "luxury perfusion" hypothesis. Anesthesiology. 1995;83:405-412.
32. Dexter F, Kern FH, Hindman BJ, Greeley WJ. The brain uses mostly dissolved oxygen during profoundly hypothermic cardiopulmonary bypass. Ann Thorac Surg. 1997;63:1725-1729.
33. Du Plessis AJ, Newburger J, Jonas RA, Hickey P, Naruse H, Tsuji M, Walsh A, Walter G, Wypij D, Volpe JJ. Cerebral oxygen supply and utilization during infant cardiac surgery. Ann Neurol. 1995;37:488-497.
34. Greeley WJ, Kern FH, Meliones JN, Ungerleider RM. Effect of deep hypothermia and circulatory arrest on cerebral blood flow and metabolism. Ann Thorac Surg. 1993;56:1464-1466.
35. Andropoulos DB, Stayer SA, McKenzie ED, Fraser CD Jr. Regional low-flow perfusion provides comparable blood flow and oxygenation to both cerebral hemispheres during neonatal aortic arch reconstruction. J Thorac Cardiovasc Surg. 2003;126:1712-1717.
36. Hoffman GM, Stuth EA, Jaquiss RD, Vanderwal PL, Staudt SR, Tro-shynski TJ, Ghanayem NS, Tweddell JS. Changes in cerebral and somatic oxygenation during stage 1 palliation of hypoplastic left heart syndrome using continuous regional cerebral perfusion. J Thorac Cardiovasc Surg. 2004;127:223-233.
37. Kurth CD, Steven JM, Nicolson SC. Cerebral oxygenation during pediatric cardiac surgery using deep hypothermic circulatory arrest. Anesthesiology. 1995;82:74-82.
38. Kussman BD, Gauvreau K, DiNardo JA, Newburger JW, Mackie AS, Booth KL, del Nido PJ, Roth SJ, Laussen PC. Cerebral perfusion and oxygenation after the Norwood procedure: comparison of right ventricle-pulmonary artery conduit with modified Blalock-Taussig shunt. J Thorac Cardiovasc Surg. 2007;133:648-655.
39. Smith M, Elwell C. Near-infrared spectroscopy: shedding light on the injured brain. Anesth Analg. 2009;108:1055-1057.
40. Elwell CE, Cope M, Edwards AD, Wyatt JS, Delpy DT, Reynolds EO. Quantification of adult cerebral hemodynamics by near-infrared spec-troscopy. J Appl Physiol. 1994;77:2753-2760.
41. Tachtsidis I, Tisdall MM, Leung TS, Pritchard C, Cooper CE, Smith M, Elwell CE. Relationship between brain tissue haemodynamics, oxygen-ation and metabolism in the healthy human adult brain during hyperoxia and hypercapnea. Adv Exp Med Biol. 2009;645:315-320.
42. Tisdall MM, Tachtsidis I, Leung TS, Elwell CE, Smith M. Near-infrared spectroscopic quantification of changes in the concentration of oxidized cytochrome c oxidase in the healthy human brain during hypoxemia. J Biomed Opt. 2007;12:024002.
43. Jonas RA, Bellinger DC, Rappaport LA, Wernovsky G, Hickey PR, Farrell DM, Newburger JW. Relation of pH strategy and developmental outcome after hypothermic circulatory arrest. J Thorac Cardiovasc Surg. 1993;106:362-368.
44. Galli KK, Zimmerman RA, Jarvik GP, Wernovsky G, Kuypers MK, Clancy RR, Montenegro LM, Mahle WT, Newman MF, Saunders AM, Nicolson SC, Spray TL, Gaynor JW. Periventricular leukomalacia is common after neonatal cardiac surgery. J Thorac Cardiovasc Surg. 2004; 127:692-704.
45. Andropoulos DB, Hunter JV, Nelson DP, Stayer SA, Stark AR, McKenzie ED, Heinle JS, Graves DE, Fraser CD Jr. Brain immaturity is associated with brain injury before and after neonatal cardiac surgery with high-flow bypass and cerebral oxygenation monitoring. J Thorac Cardiovasc Surg. 2010;139:543-556.