Characterization of two models of drug-induced constipation in mice and evaluation of mustard oil in these models

Pharmacology

Volumn 84, Issue 4, 2009, Pages 227-233

  Kojima, Ryosuke ^a   Doihara, Hitoshi ^a   Nozawa, Katsura ^a   Kawabata Shoda, Eri ^a   Yokoyama, Toshihide ^a   Ito, Hiroyuki ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Atropine; Colonic transit; Constipation; Mouse; Tegaserod; TRPA1

Indexed keywords

ALLYL ISOTHIOCYANATE; ATROPINE; CLONIDINE; LOPERAMIDE; NALOXONE; TEGASEROD; YOHIMBINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONSTIPATION; CONTROLLED STUDY; DESCENDING COLON; DISEASE MODEL; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; INTESTINE MOTILITY; INTESTINE TRANSIT TIME; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ATROPINE; CLONIDINE; CONSTIPATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GASTROINTESTINAL TRANSIT; INDOLES; LOPERAMIDE; MALE; MICE; MICE, INBRED STRAINS; MUSTARD PLANT; NALOXONE; PLANT OILS; TRANSIENT RECEPTOR POTENTIAL CHANNELS; YOHIMBINE;

EID: 70049103269     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000236524     Document Type: Article

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